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Flow cytometryAntibody data
- Antibody Data
- Antigen structure
- References [7]
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- Validations
- Flow cytometry [1]
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- Product number
- FAB1278P - Provider product page
- Provider
- R&D Systems
- Product name
- Human TREM-1 PE-conjugated Antibody
- Antibody type
- Monoclonal
- Description
- Protein A or G purified from hybridoma culture supernatant. Detects human TREM-1 in ELISAs.
- Reactivity
- Human
- Host
- Mouse
- Antigen sequence
Q9NP99- Isotype
- IgG
- Antibody clone number
- 193015
- Vial size
- 100 Tests
- Storage
- Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied.
Submitted references Activation and Regulation of Blood Vδ2 T Cells Are Amplified by TREM-1+ during Active Pulmonary Tuberculosis.
Urine TREM-1 as a marker of urinary tract infection in children.
TREM-1low is a novel characteristic for tumor-associated macrophages in lung cancer.
Differential pattern of cell-surface and soluble TREM-1 between sepsis and SIRS.
Role of MMPs in orchestrating inflammatory response in human monocytes via a TREM-1-PI3K-NF-κB pathway.
Hypoxia modulates the gene expression profile of immunoregulatory receptors in human mature dendritic cells: identification of TREM-1 as a novel hypoxic marker in vitro and in vivo.
Effects of TREM-1 activation in human neutrophils: activation of signaling pathways, recruitment into lipid rafts and association with TLR4.
Wu Y, Fang YM, Ding L, Liu X, Francisco NM, Wen J, Liao C, Ma Z, Li Z, Li M, Ming S, Liu T, Zhang M, Wu M, Jacobs M, Gong S, Huang X
Journal of immunology (Baltimore, Md. : 1950) 2018 Mar 1;200(5):1627-1638
Journal of immunology (Baltimore, Md. : 1950) 2018 Mar 1;200(5):1627-1638
Urine TREM-1 as a marker of urinary tract infection in children.
Sierra-Diaz E, Bravo Cuéllar A, Ortiz Lazareno PC, García Gutiérrez M, Georgina HF, Anaya Prado R
The Journal of international medical research 2017 Apr;45(2):631-638
The Journal of international medical research 2017 Apr;45(2):631-638
TREM-1low is a novel characteristic for tumor-associated macrophages in lung cancer.
Zhang G, Liu H, Huang J, Chen S, Pan X, Huang H, Wang L
Oncotarget 2016 Jun 28;7(26):40508-40517
Oncotarget 2016 Jun 28;7(26):40508-40517
Differential pattern of cell-surface and soluble TREM-1 between sepsis and SIRS.
Oku R, Oda S, Nakada TA, Sadahiro T, Nakamura M, Hirayama Y, Abe R, Tateishi Y, Ito M, Iseki T, Hirasawa H
Cytokine 2013 Jan;61(1):112-7
Cytokine 2013 Jan;61(1):112-7
Role of MMPs in orchestrating inflammatory response in human monocytes via a TREM-1-PI3K-NF-κB pathway.
Gómez-Piña V, Martínez E, Fernández-Ruíz I, Del Fresno C, Soares-Schanoski A, Jurado T, Siliceo M, Toledano V, Fernández-Palomares R, García-Rio F, Arnalich F, Biswas SK, López-Collazo E
Journal of leukocyte biology 2012 Jun;91(6):933-45
Journal of leukocyte biology 2012 Jun;91(6):933-45
Hypoxia modulates the gene expression profile of immunoregulatory receptors in human mature dendritic cells: identification of TREM-1 as a novel hypoxic marker in vitro and in vivo.
Bosco MC, Pierobon D, Blengio F, Raggi F, Vanni C, Gattorno M, Eva A, Novelli F, Cappello P, Giovarelli M, Varesio L
Blood 2011 Mar 3;117(9):2625-39
Blood 2011 Mar 3;117(9):2625-39
Effects of TREM-1 activation in human neutrophils: activation of signaling pathways, recruitment into lipid rafts and association with TLR4.
Fortin CF, Lesur O, Fulop T Jr
International immunology 2007 Jan;19(1):41-50
International immunology 2007 Jan;19(1):41-50
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Supportive validation
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- R&D Systems (provider)
- Main image
- Experimental details
- Detection of TREM-1 in Human Blood Granulocytes by Flow Cytometry. Human peripheral blood granulocytes were stained with Mouse Anti-Human TREM-1 PE-conjugated Monoclonal Antibody (Catalog # FAB1278P, filled histogram) or isotype control antibody (Catalog # IC002P, open histogram). View our protocol for Staining Membrane-associated Proteins.
