MAB2926

antibody from R&D Systems

Targeting: BMP10

Western blot (Recommended by provider)

Blocking/Neutralizing (Recommended by provider)

Antibody Data

Product number

MAB2926

Provider

R&D Systems

Product name

Anti-Human/Mouse BMP-10 Monoclonal Antibody (Clone 462732)

Antibody type

Monoclonal

Antigen

Chinese hamster ovary cell line CHO-derived recombinant human BMP-10, Asn317-Arg424

Description

Protein A or G purified from hybridoma culture supernatant

Reactivity

Human, Mouse

Host

Mouse

Antigen sequence

O95393


Isotype

IgG

Vial size

500 µg

References

Submitted references

A heterodimer formed by bone morphogenetic protein 9 (BMP9) and BMP10 provides most BMP biological activity in plasma.

Tillet E, Ouarné M, Desroches-Castan A, Mallet C, Subileau M, Didier R, Lioutsko A, Belthier G, Feige JJ, Bailly S
The Journal of biological chemistry 2018 Jul 13;293(28):10963-10974

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A mouse model of hereditary hemorrhagic telangiectasia generated by transmammary-delivered immunoblocking of BMP9 and BMP10.

Ruiz S, Zhao H, Chandakkar P, Chatterjee PK, Papoin J, Blanc L, Metz CN, Campagne F, Marambaud P
Scientific reports 2016 Nov 22;5:37366

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BMP9 and BMP10 are necessary for proper closure of the ductus arteriosus.

Levet S, Ouarné M, Ciais D, Coutton C, Subileau M, Mallet C, Ricard N, Bidart M, Debillon T, Faravelli F, Rooryck C, Feige JJ, Tillet E, Bailly S
Proceedings of the National Academy of Sciences of the United States of America 2015 Jun 23;112(25):E3207-15

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BMP9 and BMP10 are critical for postnatal retinal vascular remodeling.

Ricard N, Ciais D, Levet S, Subileau M, Mallet C, Zimmers TA, Lee SJ, Bidart M, Feige JJ, Bailly S
Blood 2012 Jun 21;119(25):6162-71

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Systematic analysis of gene expression differences between left and right atria in different mouse strains and in human atrial tissue.

Kahr PC, Piccini I, Fabritz L, Greber B, Schöler H, Scheld HH, Hoffmeier A, Brown NA, Kirchhof P
PloS one 2011;6(10):e26389