PAB0427

antibody from Abnova Corporation

Targeting: CDC25A

Immunohistochemistry (Supportive data in Antibodypedia)

Antibody Data

Product number

PAB0427

Provider

Abnova Corporation

Proper citation

Abnova Corporation Cat#PAB0427, RRID:AB_982422

Product name

CDC25A (phospho S278) polyclonal antibody

Antibody type

Polyclonal

Description

Rabbit polyclonal antibody raised against synthetic phosphopeptide of CDC25A.

Storage

Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.

References

Submitted references

Cdc25A and cdc25B expression in malignant lymphoma of the thyroid: correlation with histological subtypes and cell proliferation.

Ito Y, Yoshida H, Matsuzuka F, Matsuura N, Nakamura Y, Nakamine H, Kakudo K, Kuma K, Miyauchi A
International journal of molecular medicine 2004 Mar;13(3):431-5

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Activation of the Raf-1/MEK/Erk kinase pathway by a novel Cdc25 inhibitor in human prostate cancer cells.

Nemoto K, Vogt A, Oguri T, Lazo JS
The Prostate 2004 Jan 1;58(1):95-102

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Regulation of human Cdc25A stability by Serine 75 phosphorylation is not sufficient to activate a S phase checkpoint.

Goloudina A, Yamaguchi H, Chervyakova DB, Appella E, Fornace AJ Jr, Bulavin DV
Cell cycle (Georgetown, Tex.) 2003 Sep-Oct;2(5):473-8

Immunohistochemistry

Supportive validation

Submitted by

Abnova Corporation (provider)

Main image

Experimental details

Formalin-fixed and paraffin-embedded human cancer tissue reacted with CDC25A (phospho S278) polyclonal antibody (Cat # PAB0427) which was peroxidase-conjugated to the secondary antibody followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma.

Validation comment

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)