Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations [0]
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- Product number
- ABIN362127 - Provider product page
- Provider
- antibodies-online
- Proper citation
- Antibodies-Online Cat#ABIN362127, RRID:AB_10954159
- Product name
- anti-Cell Division Cycle 25 Homolog A (S. Pombe) (CDC25A) (pSer76) antibody
- Antibody type
- Polyclonal
- Antigen
- Peptide sequence around phosphorylation site of pSer76 (M-G-S (p) -S-E) derived from Human cdc25A. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.
- Description
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Epitope
- pSer76
- Isotype
- IgG
- Vial size
- 50 μL
- Concentration
- 1 mg/mL
- Storage
- Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Submitted references CK1ε targets Cdc25A for ubiquitin-mediated proteolysis under normal conditions and in response to checkpoint activation.
SCFbeta-TRCP links Chk1 signaling to degradation of the Cdc25A protein phosphatase.
Chk1 is activated transiently and targets Cdc25A for degradation at the Xenopus midblastula transition.
Piao S, Lee SJ, Xu Y, Gwak J, Oh S, Park BJ, Ha NC
Cell cycle (Georgetown, Tex.) 2011 Feb 1;10(3):531-7
Cell cycle (Georgetown, Tex.) 2011 Feb 1;10(3):531-7
SCFbeta-TRCP links Chk1 signaling to degradation of the Cdc25A protein phosphatase.
Jin J, Shirogane T, Xu L, Nalepa G, Qin J, Elledge SJ, Harper JW
Genes & development 2003 Dec 15;17(24):3062-74
Genes & development 2003 Dec 15;17(24):3062-74
Chk1 is activated transiently and targets Cdc25A for degradation at the Xenopus midblastula transition.
Shimuta K, Nakajo N, Uto K, Hayano Y, Okazaki K, Sagata N
The EMBO journal 2002 Jul 15;21(14):3694-703
The EMBO journal 2002 Jul 15;21(14):3694-703
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