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- References [3]
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- Product number
- ABIN389532 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Cell Division Cycle 25 Homolog A (S. Pombe) (CDC25A) (pThr506) antibody
- Antibody type
- Polyclonal
- Antigen
- This antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T506 of human Cdc25A.
- Reactivity
- Human
- Host
- Rabbit
- Vial size
- 400 µL
- Concentration
- 0.25 mg/ml
- Storage
- Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
Submitted references Pro-apoptotic role of Cdc25A: activation of cyclin B1/Cdc2 by the Cdc25A C-terminal domain.
14-3-3gamma mediates Cdc25A proteolysis to block premature mitotic entry after DNA damage.
DNA damage during the spindle-assembly checkpoint degrades CDC25A, inhibits cyclin-CDC2 complexes, and reverses cells to interphase.
Chou ST, Yen YC, Lee CM, Chen MS
The Journal of biological chemistry 2010 Jun 4;285(23):17833-45
The Journal of biological chemistry 2010 Jun 4;285(23):17833-45
14-3-3gamma mediates Cdc25A proteolysis to block premature mitotic entry after DNA damage.
Kasahara K, Goto H, Enomoto M, Tomono Y, Kiyono T, Inagaki M
The EMBO journal 2010 Aug 18;29(16):2802-12
The EMBO journal 2010 Aug 18;29(16):2802-12
DNA damage during the spindle-assembly checkpoint degrades CDC25A, inhibits cyclin-CDC2 complexes, and reverses cells to interphase.
Chow JP, Siu WY, Fung TK, Chan WM, Lau A, Arooz T, Ng CP, Yamashita K, Poon RY
Molecular biology of the cell 2003 Oct;14(10):3989-4002
Molecular biology of the cell 2003 Oct;14(10):3989-4002
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