ABIN965831

antibody from antibodies-online

Targeting: CDC25A

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

ABIN965831

Provider

antibodies-online

Product name

anti-Cell Division Cycle 25 Homolog A (S. Pombe) (CDC25A) (pSer75) antibody

Antigen

The antiserum was produced against synthesized phosphopeptide derived from human cdc25A around the phosphorylation site of serine 75 (M-G-SP-S-E).

Reactivity

Human, Mouse, Rat

Host

Rabbit

Vial size

100ug

Concentration

100ug/100ul.

Storage

Store at -20°C/1 year.

References

Submitted references

SCFbeta-TRCP links Chk1 signaling to degradation of the Cdc25A protein phosphatase.

Jin J, Shirogane T, Xu L, Nalepa G, Qin J, Elledge SJ, Harper JW
Genes & development 2003 Dec 15;17(24):3062-74

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Chk1 is activated transiently and targets Cdc25A for degradation at the Xenopus midblastula transition.

Shimuta K, Nakajo N, Uto K, Hayano Y, Okazaki K, Sagata N
The EMBO journal 2002 Jul 15;21(14):3694-703