Antibody data
- Antibody Data
- Antigen structure
- References [13]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- 24840-1-AP - Provider product page

- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#24840-1-AP, RRID:AB_2737406
- Product name
- SETD7 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated SETD7 antibody (Cat. #24840-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Dynamic hydrogels orchestrate the differentiation fate of mesenchymal stem cells through epigenetic regulation of SETD7 to accelerate bone defect repair.
Inhibition of Setd7 protects against cardiomyocyte hypertrophy via inhibiting lipid oxidation.
Integrated stress response promotes acute liver failure by activating SETD7 and enhancing NLRP3 methylation.
SETD7 promotes LC3B methylation and degradation in ovarian cancer.
DANCR maintained colon epithelial homeostasis by regulating the TNFα/NF-κB pathway.
Combined SET7/9 and CDK4 inhibition act synergistically against osteosarcoma.
ZKSCAN5 activates LAPTM5 expression by recruiting SETD7 to promote metastasis in pancreatic ductal adenocarcinoma.
ACAT2 suppresses the ubiquitination of YAP1 to enhance the proliferation and metastasis ability of gastric cancer via the upregulation of SETD7.
DDB1 regulates the activation-induced apoptosis of T cells via downregulating the expression of histone methyltransferase SETD7.
Proteomic analysis of DZIP3 interactome and its role in proliferation and metastasis in gastric cancer cells.
SETD7 mediates the vascular invasion in articular cartilage and chondrocytes apoptosis in osteoarthriis.
Histone-lysine N-methyltransferase SETD7 is a potential serum biomarker for colorectal cancer patients.
SETD7 is a prognosis predicting factor of breast cancer and regulates redox homeostasis.
Xie X, Hu L, Zhang Y, Mi B, Xu X, Ding C, Li Y, Al-Smadi F, Chu X, Xiong Y, Zhang K, Bian L, Liu G
Bioactive materials 2026 Jul;61:136-149
Bioactive materials 2026 Jul;61:136-149
Inhibition of Setd7 protects against cardiomyocyte hypertrophy via inhibiting lipid oxidation.
Su HB, Wang JH, Zhang YY, Xu J, Liu JY, Li YH, Xiao CX, Wang CY, Chang J, Liu XH
Acta pharmacologica Sinica 2026 Feb;47(2):344-356
Acta pharmacologica Sinica 2026 Feb;47(2):344-356
Integrated stress response promotes acute liver failure by activating SETD7 and enhancing NLRP3 methylation.
Nie Z, Liu X, Zhang H, Chen Z, Sun X, Li Y, Kong Y, Shu H, Chen W
Molecular therapy : the journal of the American Society of Gene Therapy 2026 Feb 16;
Molecular therapy : the journal of the American Society of Gene Therapy 2026 Feb 16;
SETD7 promotes LC3B methylation and degradation in ovarian cancer.
Zhang Z, Li M, Hou Y, Huang T, Zhang B, Lin Q, Shao G
The Journal of biological chemistry 2025 Feb;301(2):108134
The Journal of biological chemistry 2025 Feb;301(2):108134
DANCR maintained colon epithelial homeostasis by regulating the TNFα/NF-κB pathway.
Peng L, Shi Y, Deng J, Chen J, Xiang P, Zhong X
Biochemical and biophysical research communications 2024 Sep 3;723:150176
Biochemical and biophysical research communications 2024 Sep 3;723:150176
Combined SET7/9 and CDK4 inhibition act synergistically against osteosarcoma.
Shi Y, Wang Z, Shao Y, Guang Q, Zhang J, Liu B, Wu C, Wang Y, Sui P
Biochemical and biophysical research communications 2024 May 14;708:149808
Biochemical and biophysical research communications 2024 May 14;708:149808
ZKSCAN5 activates LAPTM5 expression by recruiting SETD7 to promote metastasis in pancreatic ductal adenocarcinoma.
Yang Y, Xie W, Qiao X, Yang J, Yao D, Zhu D
Histology and histopathology 2024 Jun;39(6):747-760
Histology and histopathology 2024 Jun;39(6):747-760
ACAT2 suppresses the ubiquitination of YAP1 to enhance the proliferation and metastasis ability of gastric cancer via the upregulation of SETD7.
Zhang M, Cai F, Guo J, Liu S, Ma G, Cai M, Zhang R, Deng J
Cell death & disease 2024 Apr 26;15(4):297
Cell death & disease 2024 Apr 26;15(4):297
DDB1 regulates the activation-induced apoptosis of T cells via downregulating the expression of histone methyltransferase SETD7.
Wu R, Wu X, Zou L, Zhou L, Mao Y
Medical oncology (Northwood, London, England) 2023 Apr 12;40(5):146
Medical oncology (Northwood, London, England) 2023 Apr 12;40(5):146
Proteomic analysis of DZIP3 interactome and its role in proliferation and metastasis in gastric cancer cells.
Qiu R, Zhao S, Lu C, Xu Z, Shu E, Weng Q, Chen W, Fang S, Chen W, Zheng L, Zhao Z, Yang Y, Ji J
Experimental cell research 2023 Apr 1;425(1):113525
Experimental cell research 2023 Apr 1;425(1):113525
SETD7 mediates the vascular invasion in articular cartilage and chondrocytes apoptosis in osteoarthriis.
Xiaoshi J, Maoquan L, Jiwei W, Jinqiu N, Ke Z
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Mar;35(3):e21283
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Mar;35(3):e21283
Histone-lysine N-methyltransferase SETD7 is a potential serum biomarker for colorectal cancer patients.
Duan B, Bai J, Qiu J, Wang J, Tong C, Wang X, Miao J, Li Z, Li W, Yang J, Huang C
EBioMedicine 2018 Nov;37:134-143
EBioMedicine 2018 Nov;37:134-143
SETD7 is a prognosis predicting factor of breast cancer and regulates redox homeostasis.
Huang R, Li X, Yu Y, Ma L, Liu S, Zong X, Zheng Q
Oncotarget 2017 Nov 7;8(55):94080-94090
Oncotarget 2017 Nov 7;8(55):94080-94090
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Supportive validation
- Submitted by
- Proteintech Group (provider)
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- Experimental details
- The SETD7 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human SETD7. This antibody recognizes human, mouse, rat antigen. The SETD7 antibody has been validated for the following applications: ELISA, WB analysis.