BS6775
antibody from Bioworld Technology, Inc
Targeting: TNFRSF14
ATAR, CD270, HVEA, HVEM, LIGHTR, TR2
Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- BS6775 - Provider product page
- Provider
- Bioworld Technology, Inc
- Product name
- TNFRSF14 polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- Recombinant full length Human TNFRSF14.
- Description
- HVEM (herpes virus entry mediator A), also known as TR2, ATAR, HVEA, LIGHTR or TNFRSF14 (tumor necrosis factor receptor superfamily, member 14), is a 283 amino acid single-pass type I membrane protein that is widely expressed, with highest expression in lung, spleen and thymus. A member of the TNF receptor superfamily, HVEM mediates the entry of herpes simplex virus (HSV) 1 and 2 into T lymphocytes by serving as an attachment site for the HSV envelope glycoprotein D (gD).HVEM acts as a receptor for two cellular ligands, secreted lymphotoxin and LIGHT. A member of the TNF superfamily produced by activated T-cell, LIGHT is suggested to induce apoptosis and suppress tumor formation. Consisting of three TNFR-Cys repeats, HVEM plays a critical role in HSV pathogenesis. HVEM is encoded by a gene located on human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome.
- Reactivity
- Human
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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Supportive validation
- Submitted by
- Bioworld Technology, Inc (provider)
- Main image
- Experimental details
- Western blot analysis of extracts of HL-60 cell lines, using TNFRSF14 antibody.