orb1088492

antibody from Biorbyt

Targeting: TNFRSF14 ATAR, CD270, HVEA, HVEM, LIGHTR, TR2

Western blot (Data presented on provider website)

ELISA (Data presented on provider website)

Immunocytochemistry (Data presented on provider website)

Immunoprecipitation (Data presented on provider website)

Flow cytometry (Data presented on provider website)

Antibody Data

Product number

orb1088492

Provider

Biorbyt

Product name

Anti-Hu CD270 Purified

Antibody type

Monoclonal

Description

CD270 is a type I transmembrane protein of the TNFR superfamily, which is expressed on resting T cells, monocytes, and immature dendritic cells. Its ligands, CD258 and CD272, differ in effect on CD270 signaling. Whereas binding to CD258 provides a costimulatory signal, binding to CD272 gives to the cell an inhibitory signal. CD270 also is recognized by herpes simplex glycoprotein D. CD258-CD270 interaction and signaling is implicated in macrophage-derived foam cell-mediated development of atherosclerotic lesions.

Reactivity

Human

Host

Mouse

Antibody clone number

CW10

Vial size

0.1 mg

Concentration

1 mg/ml

Storage

Store at 2-8°C. Do not freeze.