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LearnPP-H7147-00
antibody from Novus Biologicals
Targeting: NR2F2
ARP1, COUP-TFII, COUPTF2, COUPTFB, NF-E3, SVP40, TFCOUP2
Western blotAntibody data
- Antibody Data
- Antigen structure
- References [21]
- Comments [0]
- Validations [0]
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- Product number
- PP-H7147-00 - Provider product page
- Provider
- Novus Biologicals
- Product name
- Mouse Monoclonal COUP-TF II/NR2F2 Antibody
- Antibody type
- Monoclonal
- Description
- Protein A or G purified from ascites. This antibody specifically recognizes human COUP-TF II and cross-reacts with rat COUP-TF II. This antibody does not cross-react with human COUP-TF I or EAR2. Not yet tested in other species.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 ug
- Storage
- This antibody is stable for greater than six months when held at -20degrees C in a manual defrost freezer or at -70degrees C. Upon thawing, the antibody can be stored at 2degrees - 8degrees C for at least 1 month without detectable loss of activity. Avoid repeated freeze-thaw cycles.
Submitted references Retinoic Acid Regulates Endothelial β-catenin Expression and Pericyte Numbers in the Developing Brain Vasculature.
Abnormal arterial-venous fusions and fate specification in mouse embryos lacking blood flow.
Human and nonhuman primate meninges harbor lymphatic vessels that can be visualized noninvasively by MRI.
Distinct cortical and sub-cortical neurogenic domains for GABAergic interneuron precursor transcription factors NKX2.1, OLIG2 and COUP-TFII in early fetal human telencephalon.
Human Pluripotent Stem Cell-Derived Atrial and Ventricular Cardiomyocytes Develop from Distinct Mesoderm Populations.
The Transcription Factor Foxg1 Promotes Optic Fissure Closure in the Mouse by Suppressing Wnt8b in the Nasal Optic Stalk.
COUP-TFII regulates satellite cell function and muscular dystrophy.
Diverse Functions of Retinoic Acid in Brain Vascular Development.
Dysregulation of miRNAs-COUP-TFII-FOXM1-CENPF axis contributes to the metastasis of prostate cancer.
Instruction of circulating endothelial progenitors in vitro towards specialized blood-brain barrier and arterial phenotypes.
Molecular identification of venous progenitors in the dorsal aorta reveals an aortic origin for the cardinal vein in mammals.
Gremlin 2 promotes differentiation of embryonic stem cells to atrial fate by activation of the JNK signaling pathway.
COUP-TFII inhibits NFkappaB activation in endocrine-resistant breast cancer cells.
Endogenous purification reveals GREB1 as a key estrogen receptor regulatory factor.
Identification and characterization of nucleolin as a COUP-TFII coactivator of retinoic acid receptor β transcription in breast cancer cells.
Proposed role for COUP-TFII in regulating fetal Leydig cell steroidogenesis, perturbation of which leads to masculinization disorders in rodents.
Chicken ovalbumin upstream promoter transcription factor II regulates renin gene expression.
A regulatory circuitry comprised of miR-302 and the transcription factors OCT4 and NR2F2 regulates human embryonic stem cell differentiation.
Direct transcriptional regulation of neuropilin-2 by COUP-TFII modulates multiple steps in murine lymphatic vessel development.
SCF induces gamma-globin gene expression by regulating downstream transcription factor COUP-TFII.
The transcription factor COUP-TFII is negatively regulated by insulin and glucose via Foxo1- and ChREBP-controlled pathways.
Bonney S, Dennison BJC, Wendlandt M, Siegenthaler JA
Frontiers in cellular neuroscience 2018;12:476
Frontiers in cellular neuroscience 2018;12:476
Abnormal arterial-venous fusions and fate specification in mouse embryos lacking blood flow.
Hwa JJ, Beckouche N, Huang L, Kram Y, Lindskog H, Wang RA
Scientific reports 2017 Sep 20;7(1):11965
Scientific reports 2017 Sep 20;7(1):11965
Human and nonhuman primate meninges harbor lymphatic vessels that can be visualized noninvasively by MRI.
Absinta M, Ha SK, Nair G, Sati P, Luciano NJ, Palisoc M, Louveau A, Zaghloul KA, Pittaluga S, Kipnis J, Reich DS
eLife 2017 Oct 3;6
eLife 2017 Oct 3;6
Distinct cortical and sub-cortical neurogenic domains for GABAergic interneuron precursor transcription factors NKX2.1, OLIG2 and COUP-TFII in early fetal human telencephalon.
Alzu'bi A, Lindsay S, Kerwin J, Looi SJ, Khalil F, Clowry GJ
Brain structure & function 2017 Jul;222(5):2309-2328
Brain structure & function 2017 Jul;222(5):2309-2328
Human Pluripotent Stem Cell-Derived Atrial and Ventricular Cardiomyocytes Develop from Distinct Mesoderm Populations.
Lee JH, Protze SI, Laksman Z, Backx PH, Keller GM
Cell stem cell 2017 Aug 3;21(2):179-194.e4
Cell stem cell 2017 Aug 3;21(2):179-194.e4
The Transcription Factor Foxg1 Promotes Optic Fissure Closure in the Mouse by Suppressing Wnt8b in the Nasal Optic Stalk.
Smith R, Huang YT, Tian T, Vojtasova D, Mesalles-Naranjo O, Pollard SM, Pratt T, Price DJ, Fotaki V
The Journal of neuroscience : the official journal of the Society for Neuroscience 2017 Aug 16;37(33):7975-7993
The Journal of neuroscience : the official journal of the Society for Neuroscience 2017 Aug 16;37(33):7975-7993
COUP-TFII regulates satellite cell function and muscular dystrophy.
Xie X, Tsai SY, Tsai MJ
The Journal of clinical investigation 2016 Oct 3;126(10):3929-3941
The Journal of clinical investigation 2016 Oct 3;126(10):3929-3941
Diverse Functions of Retinoic Acid in Brain Vascular Development.
Bonney S, Harrison-Uy S, Mishra S, MacPherson AM, Choe Y, Li D, Jaminet SC, Fruttiger M, Pleasure SJ, Siegenthaler JA
The Journal of neuroscience : the official journal of the Society for Neuroscience 2016 Jul 20;36(29):7786-801
The Journal of neuroscience : the official journal of the Society for Neuroscience 2016 Jul 20;36(29):7786-801
Dysregulation of miRNAs-COUP-TFII-FOXM1-CENPF axis contributes to the metastasis of prostate cancer.
Lin SC, Kao CY, Lee HJ, Creighton CJ, Ittmann MM, Tsai SJ, Tsai SY, Tsai MJ
Nature communications 2016 Apr 25;7:11418
Nature communications 2016 Apr 25;7:11418
Instruction of circulating endothelial progenitors in vitro towards specialized blood-brain barrier and arterial phenotypes.
Boyer-Di Ponio J, El-Ayoubi F, Glacial F, Ganeshamoorthy K, Driancourt C, Godet M, Perrière N, Guillevic O, Couraud PO, Uzan G
PloS one 2014;9(1):e84179
PloS one 2014;9(1):e84179
Molecular identification of venous progenitors in the dorsal aorta reveals an aortic origin for the cardinal vein in mammals.
Lindskog H, Kim YH, Jelin EB, Kong Y, Guevara-Gallardo S, Kim TN, Wang RA
Development (Cambridge, England) 2014 Mar;141(5):1120-8
Development (Cambridge, England) 2014 Mar;141(5):1120-8
Gremlin 2 promotes differentiation of embryonic stem cells to atrial fate by activation of the JNK signaling pathway.
Tanwar V, Bylund JB, Hu J, Yan J, Walthall JM, Mukherjee A, Heaton WH, Wang WD, Potet F, Rai M, Kupershmidt S, Knapik EW, Hatzopoulos AK
Stem cells (Dayton, Ohio) 2014 Jul;32(7):1774-88
Stem cells (Dayton, Ohio) 2014 Jul;32(7):1774-88
COUP-TFII inhibits NFkappaB activation in endocrine-resistant breast cancer cells.
Litchfield LM, Appana SN, Datta S, Klinge CM
Molecular and cellular endocrinology 2014 Jan 25;382(1):358-367
Molecular and cellular endocrinology 2014 Jan 25;382(1):358-367
Endogenous purification reveals GREB1 as a key estrogen receptor regulatory factor.
Mohammed H, D'Santos C, Serandour AA, Ali HR, Brown GD, Atkins A, Rueda OM, Holmes KA, Theodorou V, Robinson JL, Zwart W, Saadi A, Ross-Innes CS, Chin SF, Menon S, Stingl J, Palmieri C, Caldas C, Carroll JS
Cell reports 2013 Feb 21;3(2):342-9
Cell reports 2013 Feb 21;3(2):342-9
Identification and characterization of nucleolin as a COUP-TFII coactivator of retinoic acid receptor β transcription in breast cancer cells.
Litchfield LM, Riggs KA, Hockenberry AM, Oliver LD, Barnhart KG, Cai J, Pierce WM Jr, Ivanova MM, Bates PJ, Appana SN, Datta S, Kulesza P, McBryan J, Young LS, Klinge CM
PloS one 2012;7(5):e38278
PloS one 2012;7(5):e38278
Proposed role for COUP-TFII in regulating fetal Leydig cell steroidogenesis, perturbation of which leads to masculinization disorders in rodents.
van den Driesche S, Walker M, McKinnell C, Scott HM, Eddie SL, Mitchell RT, Seckl JR, Drake AJ, Smith LB, Anderson RA, Sharpe RM
PloS one 2012;7(5):e37064
PloS one 2012;7(5):e37064
Chicken ovalbumin upstream promoter transcription factor II regulates renin gene expression.
Mayer S, Roeser M, Lachmann P, Ishii S, Suh JM, Harlander S, Desch M, Brunssen C, Morawietz H, Tsai SY, Tsai MJ, Hohenstein B, Hugo C, Todorov VT
The Journal of biological chemistry 2012 Jul 13;287(29):24483-91
The Journal of biological chemistry 2012 Jul 13;287(29):24483-91
A regulatory circuitry comprised of miR-302 and the transcription factors OCT4 and NR2F2 regulates human embryonic stem cell differentiation.
Rosa A, Brivanlou AH
The EMBO journal 2011 Jan 19;30(2):237-48
The EMBO journal 2011 Jan 19;30(2):237-48
Direct transcriptional regulation of neuropilin-2 by COUP-TFII modulates multiple steps in murine lymphatic vessel development.
Lin FJ, Chen X, Qin J, Hong YK, Tsai MJ, Tsai SY
The Journal of clinical investigation 2010 May;120(5):1694-707
The Journal of clinical investigation 2010 May;120(5):1694-707
SCF induces gamma-globin gene expression by regulating downstream transcription factor COUP-TFII.
Aerbajinai W, Zhu J, Kumkhaek C, Chin K, Rodgers GP
Blood 2009 Jul 2;114(1):187-94
Blood 2009 Jul 2;114(1):187-94
The transcription factor COUP-TFII is negatively regulated by insulin and glucose via Foxo1- and ChREBP-controlled pathways.
Perilhou A, Tourrel-Cuzin C, Kharroubi I, Henique C, Fauveau V, Kitamura T, Magnan C, Postic C, Prip-Buus C, Vasseur-Cognet M
Molecular and cellular biology 2008 Nov;28(21):6568-79
Molecular and cellular biology 2008 Nov;28(21):6568-79
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