Antibody data
- Antibody Data
- Antigen structure
- References [17]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
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Validation data
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- Product number
- 12319-2-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#12319-2-AP, RRID:AB_2289045
- Product name
- ACAA1 antibody
- Antibody type
- Polyclonal
- Description
- ACAA1 antibody (Cat. #12319-2-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Integration of metabolomics and transcriptomics to reveal the mechanism of Gerberae piloselloidis herba in alleviating bronchial asthma.
The Role of Neutral Sphingomyelinase-2 (NSM2) in the Control of Neutral Lipid Storage in T Cells.
MYC expression and fatty acid oxidation in EGFR-TKI acquired resistance.
Proteomics coupled transcriptomics reveals lipopolysaccharide inhibiting peroxisome proliferator-activated receptors signalling pathway to reduce lipid droplets accumulation in mouse liver.
Glycyrrhizic acid glycosides reduces extensive tripterygium glycosides-induced lipid deposition in hepatocytes.
Transmembrane protein 135 regulates lipid homeostasis through its role in peroxisomal DHA metabolism.
Comparative Genomic Analysis of the Thiolase Family and Functional Characterization of the Acetyl-Coenzyme A Acyltransferase-1 Gene for Milk Biosynthesis and Production of Buffalo and Cattle.
Peroxisomal L-bifunctional protein (EHHADH) deficiency causes male-specific kidney hypertrophy and proximal tubular injury in mice.
Murine deficiency of peroxisomal L-bifunctional protein (EHHADH) causes medium-chain 3-hydroxydicarboxylic aciduria and perturbs hepatic cholesterol homeostasis.
Short hairpin RNA attenuates liver fibrosis by regulating the PPAR‑γ and NF‑κB pathways in HBV‑induced liver fibrosis in mice.
High-Dose Dexamethasone Manipulates the Tumor Microenvironment and Internal Metabolic Pathways in Anti-Tumor Progression.
Super-resolution imaging reveals the sub-diffraction phenotype of Zellweger Syndrome ghosts and wild-type peroxisomes.
PPARγ maintains the metabolic heterogeneity and homeostasis of renal tubules.
Proteomic Analysis of Lysosomal Membrane Proteins in Bovine Mammary Epithelial Cells Illuminates Potential Novel Lysosome Functions in Lactation.
In vivo labeling of peroxisomes by photoconvertible mEos2 in myelinating glia of mice.
Functional analysis of PEX13 mutation in a Zellweger syndrome spectrum patient reveals novel homooligomerization of PEX13 and its role in human peroxisome biogenesis.
A role for myelin-associated peroxisomes in maintaining paranodal loops and axonal integrity.
Liu C, Fu C, Lu Y, Sun J, Liu T, Wang Y, Wang A, Huang Y, Li Y
Journal of ethnopharmacology 2024 May 10;325:117852
Journal of ethnopharmacology 2024 May 10;325:117852
The Role of Neutral Sphingomyelinase-2 (NSM2) in the Control of Neutral Lipid Storage in T Cells.
Schempp R, Eilts J, Schöl M, Grijalva Yépez MF, Fekete A, Wigger D, Schumacher F, Kleuser B, van Ham M, Jänsch L, Sauer M, Avota E
International journal of molecular sciences 2024 Mar 13;25(6)
International journal of molecular sciences 2024 Mar 13;25(6)
MYC expression and fatty acid oxidation in EGFR-TKI acquired resistance.
Wang G, Li T, Wan Y, Li Q
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 2024 Jan;72:101019
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 2024 Jan;72:101019
Proteomics coupled transcriptomics reveals lipopolysaccharide inhibiting peroxisome proliferator-activated receptors signalling pathway to reduce lipid droplets accumulation in mouse liver.
Ran H, Sun W, Wang L, Wang X, Yu H, Chen J, Liu F, Chao Z, Pu Q, Liu Y, Zeng Y, Li Z, Wan Y, Yuan J
Proteomics 2023 Oct;23(19):e2300043
Proteomics 2023 Oct;23(19):e2300043
Glycyrrhizic acid glycosides reduces extensive tripterygium glycosides-induced lipid deposition in hepatocytes.
Yang Y, Fu X, Xia B, Zhou L, Zhang H, Li C, Ye X, Liu T
Heliyon 2023 Jul;9(7):e17891
Heliyon 2023 Jul;9(7):e17891
Transmembrane protein 135 regulates lipid homeostasis through its role in peroxisomal DHA metabolism.
Landowski M, Bhute VJ, Grindel S, Haugstad Z, Gyening YK, Tytanic M, Brush RS, Moyer LJ, Nelson DW, Davis CR, Yen CE, Ikeda S, Agbaga MP, Ikeda A
Communications biology 2023 Jan 4;6(1):8
Communications biology 2023 Jan 4;6(1):8
Comparative Genomic Analysis of the Thiolase Family and Functional Characterization of the Acetyl-Coenzyme A Acyltransferase-1 Gene for Milk Biosynthesis and Production of Buffalo and Cattle.
Deng T, Wu J, Abdel-Shafy H, Wang X, Lv H, Shaukat A, Zhou X, Zhou Y, Sun H, Wei P, Sun N, Huang Q, Xu L, Liu M, Lin Y, Yang L, Hua G
Journal of agricultural and food chemistry 2023 Feb 13;
Journal of agricultural and food chemistry 2023 Feb 13;
Peroxisomal L-bifunctional protein (EHHADH) deficiency causes male-specific kidney hypertrophy and proximal tubular injury in mice.
Ranea-Robles P, Portman K, Bender A, Lee K, He JC, Mulholland DJ, Argmann C, Houten SM
Kidney360 2021 Sep;2(9):1441-1454
Kidney360 2021 Sep;2(9):1441-1454
Murine deficiency of peroxisomal L-bifunctional protein (EHHADH) causes medium-chain 3-hydroxydicarboxylic aciduria and perturbs hepatic cholesterol homeostasis.
Ranea-Robles P, Violante S, Argmann C, Dodatko T, Bhattacharya D, Chen H, Yu C, Friedman SL, Puchowicz M, Houten SM
Cellular and molecular life sciences : CMLS 2021 Jul;78(14):5631-5646
Cellular and molecular life sciences : CMLS 2021 Jul;78(14):5631-5646
Short hairpin RNA attenuates liver fibrosis by regulating the PPAR‑γ and NF‑κB pathways in HBV‑induced liver fibrosis in mice.
Ye L, Chen T, Cao J, Sun L, Li W, Zhang C
International journal of oncology 2020 Nov;57(5):1116-1128
International journal of oncology 2020 Nov;57(5):1116-1128
High-Dose Dexamethasone Manipulates the Tumor Microenvironment and Internal Metabolic Pathways in Anti-Tumor Progression.
Xu L, Xia H, Ni D, Hu Y, Liu J, Qin Y, Zhou Q, Yi Q, Xie Y
International journal of molecular sciences 2020 Mar 7;21(5)
International journal of molecular sciences 2020 Mar 7;21(5)
Super-resolution imaging reveals the sub-diffraction phenotype of Zellweger Syndrome ghosts and wild-type peroxisomes.
Soliman K, Göttfert F, Rosewich H, Thoms S, Gärtner J
Scientific reports 2018 May 17;8(1):7809
Scientific reports 2018 May 17;8(1):7809
PPARγ maintains the metabolic heterogeneity and homeostasis of renal tubules.
Lyu Z, Mao Z, Li Q, Xia Y, Liu Y, He Q, Wang Y, Zhao H, Lu Z, Zhou Q
EBioMedicine 2018 Dec;38:178-190
EBioMedicine 2018 Dec;38:178-190
Proteomic Analysis of Lysosomal Membrane Proteins in Bovine Mammary Epithelial Cells Illuminates Potential Novel Lysosome Functions in Lactation.
Luo C, Zhao S, Dai W, Zheng N, Wang J
Journal of agricultural and food chemistry 2018 Dec 12;66(49):13041-13049
Journal of agricultural and food chemistry 2018 Dec 12;66(49):13041-13049
In vivo labeling of peroxisomes by photoconvertible mEos2 in myelinating glia of mice.
Richert S, Kleinecke S, Günther J, Schaumburg F, Edgar J, Nienhaus GU, Nave KA, Kassmann CM
Biochimie 2014 Mar;98:127-34
Biochimie 2014 Mar;98:127-34
Functional analysis of PEX13 mutation in a Zellweger syndrome spectrum patient reveals novel homooligomerization of PEX13 and its role in human peroxisome biogenesis.
Krause C, Rosewich H, Woehler A, Gärtner J
Human molecular genetics 2013 Oct 1;22(19):3844-57
Human molecular genetics 2013 Oct 1;22(19):3844-57
A role for myelin-associated peroxisomes in maintaining paranodal loops and axonal integrity.
Kassmann CM, Quintes S, Rietdorf J, Möbius W, Sereda MW, Nientiedt T, Saher G, Baes M, Nave KA
FEBS letters 2011 Jul 21;585(14):2205-11
FEBS letters 2011 Jul 21;585(14):2205-11
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- L02 cells were subjected to SDS PAGE followed by western blot with 12319-2-AP(ACAA1 antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The ACAA1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human ACAA1. This antibody recognizes human,mouse,rat antigen. The ACAA1 antibody has been validated for the following applications: ELISA, WB, IF, IHC analysis.