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- References [20]
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- Western blot [1]
- Immunohistochemistry [2]
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- Product number
- 16619-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#16619-1-AP, RRID:AB_2143821
- Product name
- ME1 antibody
- Antibody type
- Polyclonal
- Description
- ME1 antibody (Cat. #16619-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Inhibiting G6PD by quercetin promotes degradation of EGFR T790M mutation.
Malic Enzyme 1 as a Novel Anti-Ferroptotic Regulator in Hepatic Ischemia/Reperfusion Injury.
Targeting CXCR1 alleviates hyperoxia-induced lung injury through promoting glutamine metabolism.
Proteomic analysis identifies Stomatin as a biological marker for psychological stress.
PGAM5 deacetylation mediated by SIRT2 facilitates lipid metabolism and liver cancer proliferation.
Non-oxidative pentose phosphate pathway controls regulatory T cell function by integrating metabolism and epigenetics.
miR-885-5p Inhibits Invasion and Metastasis in Gastric Cancer by Targeting Malic Enzyme 1.
USP19 exacerbates lipogenesis and colorectal carcinogenesis by stabilizing ME1.
Fasting Induces Hepatocellular Carcinoma Cell Apoptosis by Inhibiting SET8 Expression.
Short hairpin RNA attenuates liver fibrosis by regulating the PPAR‑γ and NF‑κB pathways in HBV‑induced liver fibrosis in mice.
Malic enzyme 1 is important for uterine decidualization in response to progesterone/cAMP/PKA/HB-EGF pathway.
Dissecting cell-type-specific metabolism in pancreatic ductal adenocarcinoma.
Dynamic Regulation of ME1 Phosphorylation and Acetylation Affects Lipid Metabolism and Colorectal Tumorigenesis.
Malic Enzyme 1 (ME1) is pro-oncogenic in Apc(Min/+) mice.
CDC5L drives FAH expression to promote metabolic reprogramming in melanoma.
cMyc-mediated activation of serine biosynthesis pathway is critical for cancer progression under nutrient deprivation conditions.
Enhanced gastrointestinal expression of cytosolic malic enzyme (ME1) induces intestinal and liver lipogenic gene expression and intestinal cell proliferation in mice.
Cytosolic malic enzyme 1 (ME1) mediates high fat diet-induced adiposity, endocrine profile, and gastrointestinal tract proliferation-associated biomarkers in male mice.
Nrf2 redirects glucose and glutamine into anabolic pathways in metabolic reprogramming.
Proteomic profiling of adipose tissue from Zmpste24-/- mice, a model of lipodystrophy and premature aging, reveals major changes in mitochondrial function and vimentin processing.
Ge Z, Xu M, Ge Y, Huang G, Chen D, Ye X, Xiao Y, Zhu H, Yin R, Shen H, Ma G, Qi L, Wei G, Li D, Wei S, Zhu M, Ma H, Shi Z, Wang X, Ge X, Qian X
Cell reports 2023 Nov 28;42(11):113417
Cell reports 2023 Nov 28;42(11):113417
Malic Enzyme 1 as a Novel Anti-Ferroptotic Regulator in Hepatic Ischemia/Reperfusion Injury.
Fang X, Zhang J, Li Y, Song Y, Yu Y, Cai Z, Lian F, Yang J, Min J, Wang F
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 May;10(13):e2205436
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 May;10(13):e2205436
Targeting CXCR1 alleviates hyperoxia-induced lung injury through promoting glutamine metabolism.
Qin H, Zhuang W, Liu X, Wu J, Li S, Wang Y, Liu X, Chen C, Zhang H
Cell reports 2023 Jul 25;42(7):112745
Cell reports 2023 Jul 25;42(7):112745
Proteomic analysis identifies Stomatin as a biological marker for psychological stress.
Cao Y, Ying SQ, Qiu XY, Guo J, Chen C, Li SJ, Dou G, Zheng CX, Chen D, Qiu JY, Jin Y, Sui BD, Jin F
Neurobiology of stress 2023 Jan;22:100513
Neurobiology of stress 2023 Jan;22:100513
PGAM5 deacetylation mediated by SIRT2 facilitates lipid metabolism and liver cancer proliferation.
Fu G, Li ST, Jiang Z, Mao Q, Xiong N, Li X, Hao Y, Zhang H
Acta biochimica et biophysica Sinica 2023 Aug 15;55(9):1370-1379
Acta biochimica et biophysica Sinica 2023 Aug 15;55(9):1370-1379
Non-oxidative pentose phosphate pathway controls regulatory T cell function by integrating metabolism and epigenetics.
Liu Q, Zhu F, Liu X, Lu Y, Yao K, Tian N, Tong L, Figge DA, Wang X, Han Y, Li Y, Zhu Y, Hu L, Ji Y, Xu N, Li D, Gu X, Liang R, Gan G, Wu L, Zhang P, Xu T, Hu H, Hu Z, Xu H, Ye D, Yang H, Li B, Tong X
Nature metabolism 2022 May;4(5):559-574
Nature metabolism 2022 May;4(5):559-574
miR-885-5p Inhibits Invasion and Metastasis in Gastric Cancer by Targeting Malic Enzyme 1.
Jiang Z, Cui H, Zeng S, Li L
DNA and cell biology 2021 May;40(5):694-705
DNA and cell biology 2021 May;40(5):694-705
USP19 exacerbates lipogenesis and colorectal carcinogenesis by stabilizing ME1.
Zhu Y, Gu L, Lin X, Zhou X, Lu B, Liu C, Lei C, Zhou F, Zhao Q, Prochownik EV, Li Y
Cell reports 2021 Dec 28;37(13):110174
Cell reports 2021 Dec 28;37(13):110174
Fasting Induces Hepatocellular Carcinoma Cell Apoptosis by Inhibiting SET8 Expression.
Qi J, Chen X, Wu Q, Wang J, Zhang H, Mao A, Zhu M, Miao C
Oxidative medicine and cellular longevity 2020;2020:3985089
Oxidative medicine and cellular longevity 2020;2020:3985089
Short hairpin RNA attenuates liver fibrosis by regulating the PPAR‑γ and NF‑κB pathways in HBV‑induced liver fibrosis in mice.
Ye L, Chen T, Cao J, Sun L, Li W, Zhang C
International journal of oncology 2020 Nov;57(5):1116-1128
International journal of oncology 2020 Nov;57(5):1116-1128
Malic enzyme 1 is important for uterine decidualization in response to progesterone/cAMP/PKA/HB-EGF pathway.
Yu HF, Duan CC, Yang ZQ, Wang YS, Yue ZP, Guo B
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Mar;34(3):3820-3837
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Mar;34(3):3820-3837
Dissecting cell-type-specific metabolism in pancreatic ductal adenocarcinoma.
Lau AN, Li Z, Danai LV, Westermark AM, Darnell AM, Ferreira R, Gocheva V, Sivanand S, Lien EC, Sapp KM, Mayers JR, Biffi G, Chin CR, Davidson SM, Tuveson DA, Jacks T, Matheson NJ, Yilmaz O, Vander Heiden MG
eLife 2020 Jul 10;9
eLife 2020 Jul 10;9
Dynamic Regulation of ME1 Phosphorylation and Acetylation Affects Lipid Metabolism and Colorectal Tumorigenesis.
Zhu Y, Gu L, Lin X, Liu C, Lu B, Cui K, Zhou F, Zhao Q, Prochownik EV, Fan C, Li Y
Molecular cell 2020 Jan 2;77(1):138-149.e5
Molecular cell 2020 Jan 2;77(1):138-149.e5
Malic Enzyme 1 (ME1) is pro-oncogenic in Apc(Min/+) mice.
Fernandes LM, Al-Dwairi A, Simmen RCM, Marji M, Brown DM, Jewell SW, Simmen FA
Scientific reports 2018 Sep 24;8(1):14268
Scientific reports 2018 Sep 24;8(1):14268
CDC5L drives FAH expression to promote metabolic reprogramming in melanoma.
Gu Z, Zhang H, Li Y, Shen S, Yin X, Zhang W, Cheng R, Zhang Y, Zhang X, Chen H, Huang B, Cao Y
Oncotarget 2017 Dec 26;8(69):114328-114343
Oncotarget 2017 Dec 26;8(69):114328-114343
cMyc-mediated activation of serine biosynthesis pathway is critical for cancer progression under nutrient deprivation conditions.
Sun L, Song L, Wan Q, Wu G, Li X, Wang Y, Wang J, Liu Z, Zhong X, He X, Shen S, Pan X, Li A, Wang Y, Gao P, Tang H, Zhang H
Cell research 2015 Apr;25(4):429-44
Cell research 2015 Apr;25(4):429-44
Enhanced gastrointestinal expression of cytosolic malic enzyme (ME1) induces intestinal and liver lipogenic gene expression and intestinal cell proliferation in mice.
Al-Dwairi A, Brown AR, Pabona JM, Van TH, Hamdan H, Mercado CP, Quick CM, Wight PA, Simmen RC, Simmen FA
PloS one 2014;9(11):e113058
PloS one 2014;9(11):e113058
Cytosolic malic enzyme 1 (ME1) mediates high fat diet-induced adiposity, endocrine profile, and gastrointestinal tract proliferation-associated biomarkers in male mice.
Al-Dwairi A, Pabona JM, Simmen RC, Simmen FA
PloS one 2012;7(10):e46716
PloS one 2012;7(10):e46716
Nrf2 redirects glucose and glutamine into anabolic pathways in metabolic reprogramming.
Mitsuishi Y, Taguchi K, Kawatani Y, Shibata T, Nukiwa T, Aburatani H, Yamamoto M, Motohashi H
Cancer cell 2012 Jul 10;22(1):66-79
Cancer cell 2012 Jul 10;22(1):66-79
Proteomic profiling of adipose tissue from Zmpste24-/- mice, a model of lipodystrophy and premature aging, reveals major changes in mitochondrial function and vimentin processing.
Peinado JR, Quirós PM, Pulido MR, Mariño G, Martínez-Chantar ML, Vázquez-Martínez R, Freije JM, López-Otín C, Malagón MM
Molecular & cellular proteomics : MCP 2011 Nov;10(11):M111.008094
Molecular & cellular proteomics : MCP 2011 Nov;10(11):M111.008094
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse liver tissue were subjected to SDS PAGE followed by western blot with 16619-1-AP(ME1 antibody) at dilution of 1:2000
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human liver using 16619-1-AP(ME1 antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The ME1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human ME1. This antibody recognizes human,mouse,rat antigen. The ME1 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
