Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- BS1359 - Provider product page
- Provider
- Bioworld Technology, Inc
- Proper citation
- Bioworld Technology Cat#BS1359, RRID:AB_1663472
- Product name
- TGFÏ« (R139) polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- Synthetic peptide, corresponding to amino acids 111-160 of Human TGFÏ«.
- Description
- Transforming growth factor Ï« (TGFÏ«) is an acid- and heat-stable 50 amino acid protein originally found in rodents and humans. TGFÏ« is 33% homologous at the amino acid level to epidermal growth factor (EGF). TGFÏ« binds to the EGF receptor, mediates tyrosine phosphorylation of the receptor and promotes anchorage-independent growth of normal rat fibroblasts in soft agar in the presence of transforming growth factor ÉÇ. TGFÏ« is secreted by a variety of transformed cells and tumors, embryonic cells and some normal adult cells. TGFÏ« bioactivity has been found in the urine of cancer patients. It has been suggested that it may act as an autocrine growth factor for the induction or maintenance of malignancy.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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Supportive validation
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- Bioworld Technology, Inc (provider)
- Main image
- Experimental details
- Western blot (WB) analysis of TGF¦Á (R139) pAb at 1:500 dilutionLane1: HEK293T cell lysateLane2:Mouse kidney tissue lysateLane3:Mouse liver tissue lysateLane4:Rat kidney tissue lysate