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Learn18658-1-AP
antibody from Proteintech Group
Targeting: NR5A1
AD4BP, ELP, FTZ1, FTZF1, hSF-1, SF-1, SF1
Western blot
ELISAAntibody data
- Antibody Data
- Antigen structure
- References [14]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
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- Product number
- 18658-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#18658-1-AP, RRID:AB_10596916
- Product name
- NR5A1 antibody
- Antibody type
- Polyclonal
- Description
- NR5A1 antibody (Cat. #18658-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Pharmacogenomic analysis in adrenocortical carcinoma reveals genetic features associated with mitotane sensitivity and potential therapeutics.
Seasonal changes of vitamin D(3) and ovarian steroidogenesis in the wild ground squirrels (Citellus dauricus Brandt).
Expression of cholesterol synthesis and steroidogenic markers in females of the Chinese brown frog (Rana dybowskii) during prespawning and prehibernation.
Identification of Key Differentially Methylated/Expressed Genes and Pathways for Ovarian Endometriosis by Bioinformatics Analysis.
Nicotinamide N-Methyltransferase inhibits HBV replication by suppressing NR5A1 expression invitro.
Icariin promotes mouse Leydig cell testosterone synthesis via the Esr1/Src/Akt/Creb/Sf-1 pathway.
Pde8b haploinsufficiency in mice is associated with modest adrenal defects, impaired steroidogenesis, and male infertility, unaltered by concurrent PKA or Wnt activation.
Screening and Identification of Differential Ovarian Proteins before and after Induced Ovulation via Seminal Plasma in Bactrian Camels.
PRMT5 regulates ovarian follicle development by facilitating Wt1 translation.
Seasonal expressions of SF-1, StAR and P450scc in the scent glands of the muskrats (Ondatra zibethicus).
Inactivation of Wt1 causes pre-granulosa cell to steroidogenic cell transformation and defect of ovary development†.
Transactivation of miR-202-5p by Steroidogenic Factor 1 (SF1) Induces Apoptosis in Goat Granulosa Cells by Targeting TGFβR2.
Icariin protects mouse Leydig cell testosterone synthesis from the adverse effects of di(2-ethylhexyl) phthalate.
Induction of Sertoli-like cells from human fibroblasts by NR5A1 and GATA4.
Zhang J, Wu L, Su T, Liu H, Jiang L, Jiang Y, Wu Z, Chen L, Li H, Zheng J, Sun Y, Peng H, Han R, Ning G, Ye L, Wang W
Frontiers in endocrinology 2024;15:1365321
Frontiers in endocrinology 2024;15:1365321
Seasonal changes of vitamin D(3) and ovarian steroidogenesis in the wild ground squirrels (Citellus dauricus Brandt).
Lu W, Zhou Y, Liu Y, Zhang H, Yuan Z, Han Y, Weng Q
The Journal of steroid biochemistry and molecular biology 2023 Nov;234:106385
The Journal of steroid biochemistry and molecular biology 2023 Nov;234:106385
Expression of cholesterol synthesis and steroidogenic markers in females of the Chinese brown frog (Rana dybowskii) during prespawning and prehibernation.
Chen Y, Liu Y, Wang Y, Zhang Y, Xie W, Zhang H, Weng Q, Xu M
American journal of physiology. Regulatory, integrative and comparative physiology 2023 Dec 1;325(6):R750-R758
American journal of physiology. Regulatory, integrative and comparative physiology 2023 Dec 1;325(6):R750-R758
Identification of Key Differentially Methylated/Expressed Genes and Pathways for Ovarian Endometriosis by Bioinformatics Analysis.
Zhang H, Wu J, Li Y, Jin G, Tian Y, Kang S
Reproductive sciences (Thousand Oaks, Calif.) 2022 May;29(5):1630-1643
Reproductive sciences (Thousand Oaks, Calif.) 2022 May;29(5):1630-1643
Nicotinamide N-Methyltransferase inhibits HBV replication by suppressing NR5A1 expression invitro.
Fan SY, Long SY, Liu JJ, Zhang WL, Hu JL
Biochemical and biophysical research communications 2022 Jul 23;614:70-77
Biochemical and biophysical research communications 2022 Jul 23;614:70-77
Icariin promotes mouse Leydig cell testosterone synthesis via the Esr1/Src/Akt/Creb/Sf-1 pathway.
Sun J, Xu W, Zheng S, Lv C, Lin J, Chen S, Qiu Y, Jiang X, Draz E, Wang S
Toxicology and applied pharmacology 2022 Apr 15;441:115969
Toxicology and applied pharmacology 2022 Apr 15;441:115969
Pde8b haploinsufficiency in mice is associated with modest adrenal defects, impaired steroidogenesis, and male infertility, unaltered by concurrent PKA or Wnt activation.
Leal LF, Szarek E, Berthon A, Nesterova M, Faucz FR, London E, Mercier C, Abu-Asab M, Starost MF, Dye L, Bilinska B, Kotula-Balak M, Antonini SR, Stratakis CA
Molecular and cellular endocrinology 2021 Feb 15;522:111117
Molecular and cellular endocrinology 2021 Feb 15;522:111117
Screening and Identification of Differential Ovarian Proteins before and after Induced Ovulation via Seminal Plasma in Bactrian Camels.
Wang Q, Zhang Q, Li Y, Zhao X, Zhang Y
Animals : an open access journal from MDPI 2021 Dec 9;11(12)
Animals : an open access journal from MDPI 2021 Dec 9;11(12)
PRMT5 regulates ovarian follicle development by facilitating Wt1 translation.
Chen M, Dong F, Chen M, Shen Z, Wu H, Cen C, Cui X, Bao S, Gao F
eLife 2021 Aug 27;10
eLife 2021 Aug 27;10
Seasonal expressions of SF-1, StAR and P450scc in the scent glands of the muskrats (Ondatra zibethicus).
Xie W, Tang Z, Xu L, Zhong J, Zhang H, Han Y, Yuan Z, Weng Q
The Journal of steroid biochemistry and molecular biology 2020 Nov;204:105766
The Journal of steroid biochemistry and molecular biology 2020 Nov;204:105766
Inactivation of Wt1 causes pre-granulosa cell to steroidogenic cell transformation and defect of ovary development†.
Cen C, Chen M, Zhou J, Zhang L, Duo S, Jiang L, Hou X, Gao F
Biology of reproduction 2020 Jun 23;103(1):60-69
Biology of reproduction 2020 Jun 23;103(1):60-69
Transactivation of miR-202-5p by Steroidogenic Factor 1 (SF1) Induces Apoptosis in Goat Granulosa Cells by Targeting TGFβR2.
Ding Q, Jin M, Wang Y, Liu J, Kalds P, Wang Y, Yang Y, Wang X, Chen Y
Cells 2020 Feb 14;9(2)
Cells 2020 Feb 14;9(2)
Icariin protects mouse Leydig cell testosterone synthesis from the adverse effects of di(2-ethylhexyl) phthalate.
Sun J, Wang D, Lin J, Liu Y, Xu L, Lv R, Mo K, Lian X, Xie M, Xu S, Wang S
Toxicology and applied pharmacology 2019 Sep 1;378:114612
Toxicology and applied pharmacology 2019 Sep 1;378:114612
Induction of Sertoli-like cells from human fibroblasts by NR5A1 and GATA4.
Liang J, Wang N, He J, Du J, Guo Y, Li L, Wu W, Yao C, Li Z, Kee K
eLife 2019 Nov 11;8
eLife 2019 Nov 11;8
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse ovary tissue were subjected to SDS PAGE followed by western blot with 18658-1-AP(NR5A1 antibody) at dilution of 1:1000
- Sample type
- tissue
Supportive validation
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The NR5A1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human NR5A1. This antibody recognizes human,mouse,rat antigen. The NR5A1 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human liver using 18658-1-AP(NR5A1 antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
