Antibody data
- Antibody Data
- Antigen structure
- References [6]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
Reference
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- Product number
- 12712-1-AP - Provider product page

- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#12712-1-AP, RRID:AB_10640439
- Product name
- GCNF antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated GCNF antibody (Cat. #12712-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references NR6A1 is essential for neural crest cell specification, formation and survival.
RalB uncoupling from exocyst is required for endothelial Weibel-Palade body exocytosis.
Mitofusin 2 Mediates the Protective Effect of NR6A1 Silencing Against Neuronal Injury in Experimental Stroke Models.
Establishment of a Prognostic Model for Hepatocellular Carcinoma Based on Bioinformatics and the Role of NR6A1 in the Progression of HCC.
Hippocampal NR6A1 impairs CREB-BDNF signaling and leads to the development of depression-like behaviors in mice.
microRNA-196a-5p inhibits testicular germ cell tumor progression via NR6A1/E-cadherin axis.
Moore Zajic EL, Muñoz WA, Dennis JF, Bhatt S, Sakai D, Achilleos A, Zhao R, Lamb M, Price AJ, Seidel C, Tiana M, Barral A, Clawson D, Manzanares M, Trainor PA
Nature communications 2026 Jan 29;17(1)
Nature communications 2026 Jan 29;17(1)
RalB uncoupling from exocyst is required for endothelial Weibel-Palade body exocytosis.
Yang M, Boye-Doe A, Ali M, Abosabie SAS, Barr AM, Mendez LM, Sharda AV
Molecular biology of the cell 2025 May 1;36(5):ar62
Molecular biology of the cell 2025 May 1;36(5):ar62
Mitofusin 2 Mediates the Protective Effect of NR6A1 Silencing Against Neuronal Injury in Experimental Stroke Models.
Xu B, Liu Z, Chen K, Zhao Q, Wen H, Lin J, Xu J, Wang H, Wang H, Wang Y
Molecular neurobiology 2025 Jun;62(6):6811-6826
Molecular neurobiology 2025 Jun;62(6):6811-6826
Establishment of a Prognostic Model for Hepatocellular Carcinoma Based on Bioinformatics and the Role of NR6A1 in the Progression of HCC.
Lin ZH, Zhang J, Zhuang LK, Xin YN, Xuan SY
Journal of clinical and translational hepatology 2022 Oct 28;10(5):901-912
Journal of clinical and translational hepatology 2022 Oct 28;10(5):901-912
Hippocampal NR6A1 impairs CREB-BDNF signaling and leads to the development of depression-like behaviors in mice.
Tan P, Xue T, Wang Y, Hu Z, Su J, Yang R, Ji J, Ye M, Chen Z, Huang C, Lu X
Neuropharmacology 2022 May 15;209:108990
Neuropharmacology 2022 May 15;209:108990
microRNA-196a-5p inhibits testicular germ cell tumor progression via NR6A1/E-cadherin axis.
Liu X, Fan Z, Li Y, Li Z, Zhou Z, Yu X, Wan J, Min Z, Yang L, Li D
Cancer medicine 2020 Dec;9(23):9107-9122
Cancer medicine 2020 Dec;9(23):9107-9122
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- PC-3 cells were subjected to SDS PAGE followed by western blot with 12712-1-AP(NR6A1 antibody) at dilution of 1:300
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- The GCNF antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human GCNF. This antibody recognizes human,mouse,rat antigen. The GCNF antibody has been validated for the following applications: ELISA, WB, IHC analysis.