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- Antibody Data
- Antigen structure
- References [10]
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- Validations
- Flow cytometry [1]
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- Product number
- AF-242-PB - Provider product page
- Provider
- R&D Systems
- Product name
- Human TGF-beta RIII Antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified. Detects human TGF-beta RIII in direct ELISAs and Western blots. In direct ELISAs, approximately 25% cross-reactivity with recombinant mouse (rm) TGF-beta RIII is observed, and less than 1% cross-reactivity with recombinant human (rh) TGF-beta RI, rhTGF-beta RII, rhTGF-beta RIIB, and rmTGF-beta RI is observed.
- Reactivity
- Human
- Host
- Goat
- Conjugate
- Unconjugated
- Antigen sequence
AAA67061- Isotype
- IgG
- Vial size
- 250 ug
- Concentration
- LYOPH
- Storage
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Submitted references Altering the Proteoglycan State of Transforming Growth Factor β Type III Receptor (TβRIII)/Betaglycan Modulates Canonical Wnt/β-Catenin Signaling.
TWIST1-Induced miR-424 Reversibly Drives Mesenchymal Programming while Inhibiting Tumor Initiation.
Molecular signatures and transcriptional regulatory networks of human immature decidual NK and mature peripheral NK cells.
Expression of growth factors and growth factor receptor in non-healing and healing ischaemic ulceration.
Inhibin alpha-subunit and the inhibin coreceptor betaglycan are downregulated in endometrial carcinoma.
Extracellular domain of TGFbeta type III receptor inhibits angiogenesis and tumor growth in human cancer cells.
TGF-beta1 regulates TGF-beta1 and FGF-2 mRNA expression during fibroblast wound healing.
TGF-beta1 regulates TGF-beta1 and FGF-2 mRNA expression during fibroblast wound healing.
Transforming growth factor-beta1 regulation of growth zone chondrocytes is mediated by multiple interacting pathways.
Transforming growth factor-beta1 regulation of growth zone chondrocytes is mediated by multiple interacting pathways.
Jenkins LM, Singh P, Varadaraj A, Lee NY, Shah S, Flores HV, O'Connell K, Mythreye K
The Journal of biological chemistry 2016 Dec 2;291(49):25716-25728
The Journal of biological chemistry 2016 Dec 2;291(49):25716-25728
TWIST1-Induced miR-424 Reversibly Drives Mesenchymal Programming while Inhibiting Tumor Initiation.
Drasin DJ, Guarnieri AL, Neelakantan D, Kim J, Cabrera JH, Wang CA, Zaberezhnyy V, Gasparini P, Cascione L, Huebner K, Tan AC, Ford HL
Cancer research 2015 May 1;75(9):1908-21
Cancer research 2015 May 1;75(9):1908-21
Molecular signatures and transcriptional regulatory networks of human immature decidual NK and mature peripheral NK cells.
Wang F, Zhou Y, Fu B, Wu Y, Zhang R, Sun R, Tian Z, Wei H
European journal of immunology 2014 Sep;44(9):2771-84
European journal of immunology 2014 Sep;44(9):2771-84
Expression of growth factors and growth factor receptor in non-healing and healing ischaemic ulceration.
Murphy MO, Ghosh J, Fulford P, Khwaja N, Halka AT, Carter A, Turner NJ, Walker MG
European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery 2006 May;31(5):516-22
European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery 2006 May;31(5):516-22
Inhibin alpha-subunit and the inhibin coreceptor betaglycan are downregulated in endometrial carcinoma.
Florio P, Ciarmela P, Reis FM, Toti P, Galleri L, Santopietro R, Tiso E, Tosi P, Petraglia F
European journal of endocrinology 2005 Feb;152(2):277-84
European journal of endocrinology 2005 Feb;152(2):277-84
Extracellular domain of TGFbeta type III receptor inhibits angiogenesis and tumor growth in human cancer cells.
Bandyopadhyay A, Zhu Y, Malik SN, Kreisberg J, Brattain MG, Sprague EA, Luo J, López-Casillas F, Sun LZ
Oncogene 2002 May 16;21(22):3541-51
Oncogene 2002 May 16;21(22):3541-51
TGF-beta1 regulates TGF-beta1 and FGF-2 mRNA expression during fibroblast wound healing.
Song QH, Klepeis VE, Nugent MA, Trinkaus-Randall V
Molecular pathology : MP 2002 Jun;55(3):164-76
Molecular pathology : MP 2002 Jun;55(3):164-76
TGF-beta1 regulates TGF-beta1 and FGF-2 mRNA expression during fibroblast wound healing.
Song QH, Klepeis VE, Nugent MA, Trinkaus-Randall V
Molecular pathology : MP 2002 Jun;55(3):164-76
Molecular pathology : MP 2002 Jun;55(3):164-76
Transforming growth factor-beta1 regulation of growth zone chondrocytes is mediated by multiple interacting pathways.
Rosado E, Schwartz Z, Sylvia VL, Dean DD, Boyan BD
Biochimica et biophysica acta 2002 Jun 12;1590(1-3):1-15
Biochimica et biophysica acta 2002 Jun 12;1590(1-3):1-15
Transforming growth factor-beta1 regulation of growth zone chondrocytes is mediated by multiple interacting pathways.
Rosado E, Schwartz Z, Sylvia VL, Dean DD, Boyan BD
Biochimica et biophysica acta 2002 Jun 12;1590(1-3):1-15
Biochimica et biophysica acta 2002 Jun 12;1590(1-3):1-15
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Supportive validation
- Submitted by
- R&D Systems (provider)
- Main image
- Experimental details
- Detection of TGF-beta RIII in PC-3 Human Cell Line by Flow Cytometry. PC-3 human prostate cancer cell line was stained with Goat Anti-Human TGF-beta RIII Antigen Affinity-purified Polyclonal Antibody (Catalog # AF-242-PB, filled histogram) or isotype control antibody (Catalog # AB-108-C, open histogram), followed by Fluorescein-conjugated Anti-Goat IgG Secondary Antibody (Catalog # F0109).
