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- Antibody Data
- Antigen structure
- References [4]
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- Validations
- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- ABIN500501 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-ArfGAP with GTPase Domain, Ankyrin Repeat and PH Domain 2 (AGAP2) (C-Term) antibody
- Antibody type
- Polyclonal
- Antigen
- PIKE antibody was raised against a peptide corresponding to 15 amino acids near theC-terminus of human PIKE.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 0.1 mg
- Storage
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer. Avoid repeatedfreezing and thawing. Shelf life: one year from despatch.
Submitted references PIKE (phosphatidylinositol 3-kinase enhancer)-A GTPase stimulates Akt activity and mediates cellular invasion.
PI3 kinase enhancer-Homer complex couples mGluRI to PI3 kinase, preventing neuronal apoptosis.
Cytohesins and centaurins: mediators of PI 3-kinase-regulated Arf signaling.
Pike. A nuclear gtpase that enhances PI3kinase activity and is regulated by protein 4.1N.
Ahn JY, Rong R, Kroll TG, Van Meir EG, Snyder SH, Ye K
The Journal of biological chemistry 2004 Apr 16;279(16):16441-51
The Journal of biological chemistry 2004 Apr 16;279(16):16441-51
PI3 kinase enhancer-Homer complex couples mGluRI to PI3 kinase, preventing neuronal apoptosis.
Rong R, Ahn JY, Huang H, Nagata E, Kalman D, Kapp JA, Tu J, Worley PF, Snyder SH, Ye K
Nature neuroscience 2003 Nov;6(11):1153-61
Nature neuroscience 2003 Nov;6(11):1153-61
Cytohesins and centaurins: mediators of PI 3-kinase-regulated Arf signaling.
Jackson TR, Kearns BG, Theibert AB
Trends in biochemical sciences 2000 Oct;25(10):489-95
Trends in biochemical sciences 2000 Oct;25(10):489-95
Pike. A nuclear gtpase that enhances PI3kinase activity and is regulated by protein 4.1N.
Ye K, Hurt KJ, Wu FY, Fang M, Luo HR, Hong JJ, Blackshaw S, Ferris CD, Snyder SH
Cell 2000 Dec 8;103(6):919-30
Cell 2000 Dec 8;103(6):919-30
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Western blot analysis of PIKE in mouse brain cell lysates with AP30672PU-N at (A) 0.5, (B) 1, and (C) 2 ?g/ml.
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Immunohistochemistry of PIKE in mouse brain tissue with AP30672PU-N at 10 ?g/ml.
