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- References [7]
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- Product number
- 24944-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- ME2 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated ME2 antibody (Cat. #24944-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IHC, IP, WB, ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Glutamine supports human cytomegalovirus induced lipidome remodeling through reductive carboxylation.
Sirtuin 3-mediated delactylation of malic enzyme 2 disrupts redox balance and inhibits colorectal cancer growth.
SIRT5-mediated ME2 desuccinylation promotes cancer growth by enhancing mitochondrial respiration.
AKT1 phosphorylation of cytoplasmic ME2 induces a metabolic switch to glycolysis for tumorigenesis.
Differential Inhibition of Anaplerotic Pyruvate Carboxylation and Glutaminolysis-Fueled Anabolism Underlies Distinct Toxicity of Selenium Agents in Human Lung Cancer.
SUCLG2 Regulates Mitochondrial Dysfunction through Succinylation in Lung Adenocarcinoma.
cMyc-mediated activation of serine biosynthesis pathway is critical for cancer progression under nutrient deprivation conditions.
Mokry RL, de Lacy CB, Purdy JG
bioRxiv : the preprint server for biology 2026 Jan 27;
bioRxiv : the preprint server for biology 2026 Jan 27;
Sirtuin 3-mediated delactylation of malic enzyme 2 disrupts redox balance and inhibits colorectal cancer growth.
Li C, Ge C, Wang Q, Teng P, Jia H, Yao S, Huang Z
Cellular oncology (Dordrecht, Netherlands) 2025 Aug;48(4):979-990
Cellular oncology (Dordrecht, Netherlands) 2025 Aug;48(4):979-990
SIRT5-mediated ME2 desuccinylation promotes cancer growth by enhancing mitochondrial respiration.
Teng P, Cui K, Yao S, Fei B, Ling F, Li C, Huang Z
Cell death and differentiation 2024 Jan;31(1):65-77
Cell death and differentiation 2024 Jan;31(1):65-77
AKT1 phosphorylation of cytoplasmic ME2 induces a metabolic switch to glycolysis for tumorigenesis.
Chen T, Xie S, Cheng J, Zhao Q, Wu H, Jiang P, Du W
Nature communications 2024 Jan 23;15(1):686
Nature communications 2024 Jan 23;15(1):686
Differential Inhibition of Anaplerotic Pyruvate Carboxylation and Glutaminolysis-Fueled Anabolism Underlies Distinct Toxicity of Selenium Agents in Human Lung Cancer.
Fan TW, Winnike J, Al-Attar A, Belshoff AC, Lorkiewicz PK, Tan JL, Wu M, Higashi RM, Lane AN
Metabolites 2023 Jun 21;13(7)
Metabolites 2023 Jun 21;13(7)
SUCLG2 Regulates Mitochondrial Dysfunction through Succinylation in Lung Adenocarcinoma.
Hu Q, Xu J, Wang L, Yuan Y, Luo R, Gan M, Wang K, Zhao T, Wang Y, Han T, Wang JB
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Dec;10(35):e2303535
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Dec;10(35):e2303535
cMyc-mediated activation of serine biosynthesis pathway is critical for cancer progression under nutrient deprivation conditions.
Sun L, Song L, Wan Q, Wu G, Li X, Wang Y, Wang J, Liu Z, Zhong X, He X, Shen S, Pan X, Li A, Wang Y, Gao P, Tang H, Zhang H
Cell research 2015 Apr;25(4):429-44
Cell research 2015 Apr;25(4):429-44
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The ME2 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human ME2. This antibody recognizes human antigen. The ME2 antibody has been validated for the following applications: ELISA, WB analysis.
