Antibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Immunohistochemistry [1]
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Validation data
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- Product number
- HPA008880 - Provider product page
- Provider
- Atlas Antibodies
- Proper citation
- Atlas Antibodies Cat#HPA008880, RRID:AB_1853702
- Product name
- Anti-ME2
- Antibody type
- Polyclonal
- Description
- Polyclonal Antibody against Human ME2, Gene description: malic enzyme 2, NAD(+)-dependent, mitochondrial, Validated applications: WB, IHC, Uniprot ID: P23368, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µl
- Concentration
- 0.1 mg/ml
- Storage
- Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Handling
- The antibody solution should be gently mixed before use.
Submitted references Mitochondrial Malic Enzyme 3 Is Important for Insulin Secretion in Pancreatic β-Cells
Mitochondrial malic enzyme (ME2) in pancreatic islets of the human, rat and mouse and clonal insulinoma cells
Succinate is the controller of O 2 − /H2O2 release at mitochondrial complex I : negative modulation by malate, positive by cyanide
Chronic Reduction of the Cytosolic or Mitochondrial NAD(P)-malic Enzyme Does Not Affect Insulin Secretion in a Rat Insulinoma Cell Line
Mitochondrial malic enzyme (ME2) in pancreatic islets of the human, rat and mouse and clonal insulinoma cells.
Hasan N, Longacre M, Stoker S, Kendrick M, MacDonald M
Molecular Endocrinology 2015;29(3):396-410
Molecular Endocrinology 2015;29(3):396-410
Mitochondrial malic enzyme (ME2) in pancreatic islets of the human, rat and mouse and clonal insulinoma cells
MacDonald M, Longacre M, Kendrick M
Archives of Biochemistry and Biophysics 2009;488(2):100-104
Archives of Biochemistry and Biophysics 2009;488(2):100-104
Succinate is the controller of O 2 − /H2O2 release at mitochondrial complex I : negative modulation by malate, positive by cyanide
Zoccarato F, Cavallini L, Alexandre A
Journal of Bioenergetics and Biomembranes 2009;41(4):387-393
Journal of Bioenergetics and Biomembranes 2009;41(4):387-393
Chronic Reduction of the Cytosolic or Mitochondrial NAD(P)-malic Enzyme Does Not Affect Insulin Secretion in a Rat Insulinoma Cell Line
Brown L, Longacre M, Hasan N, Kendrick M, Stoker S, MacDonald M
Journal of Biological Chemistry 2009;284(51):35359-35367
Journal of Biological Chemistry 2009;284(51):35359-35367
Mitochondrial malic enzyme (ME2) in pancreatic islets of the human, rat and mouse and clonal insulinoma cells.
MacDonald MJ, Longacre MJ, Kendrick MA
Archives of biochemistry and biophysics 2009 Aug 15;488(2):100-4
Archives of biochemistry and biophysics 2009 Aug 15;488(2):100-4
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Supportive validation
- Submitted by
- Atlas Antibodies (provider)
- Enhanced method
- Orthogonal validation
- Main image
- Experimental details
- Immunohistochemistry analysis in human duodenum and liver tissues using Anti-ME2 antibody. Corresponding ME2 RNA-seq data are presented for the same tissues.
- Sample type
- Human
- Protocol
- Protocol