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- Product number
- 15184-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#15184-1-AP, RRID:AB_2084676
- Product name
- CPT1A antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated CPT1A antibody (Cat. #15184-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IF, IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Cyanobacteria-derived near-infrared autofluorescent exosomes enabling synergistic brain lesion imaging and neuroprotection.
Interleukin-10 Derived Apoptotic Vesicles Enhance Scarless Skin Healing by Modulating Fibroblast Metabolism and Fibrosis Pathways.
Acox1 induces lipid peroxidation and metabolic shifting to promote PASMCs proliferation in hypoxia-induced pulmonary hypertension.
Xiayuxue decoction alleviates MASH by regulating gut microbiota, bile acid metabolism, and m(6)A modification.
Integrated Proteomics and Metabolomics Reveal the Direct Hepatic Protection of Propionate Against Alcoholic Liver Disease via the RGN-PPARα Pathway.
Asymmetric dimethylguanidino valeric acid as an independently associated risk factor for early hypertriglyceridemia and dyslipidemia.
Fermented Black Soybean and Dehulled Adlay Improve Metabolic Syndrome via AMPK-SIRT1 Activation and Gut Microbiota Modulation.
Dendrobium officinale polysaccharide ameliorate hyperlipidemia through LKB1/AMPK and CD36/PGC-1α/UCP1 activation and gut microbiota modulation.
cGAS-STING signaling pathway promotes ischemic kidney injury by regulating HK3-mediated lipid accumulation.
Atractylodin ameliorates obesity-associated hepatic steatosis by regulating the PLIN2-ATGL/CPT1A axis-mediated lipid droplet-mitochondria interactions.
Caveolin-1 deficiency exacerbates liver fibrosis by driving lipid metabolic reprogramming in hepatic stellate cells via DRP1-mediated mitochondrial fission.
Monascus pilosus SWM-008-Fermented Red Mold Rice and Its Monascinol Ameliorate Non-Alcoholic Fatty Liver Disease via Activation of the AMPK-ATGL Pathway and Enrichment of Butyrate-Producing Bacteria.
PGC-1α Transcriptionally Regulated by ChREBP Mitigates Neuropathic Pain Through Promoting Microglial Fatty Acid Oxidation and Anti-Inflammatory Response.
Thallium exposure disturbs gut microbiota composition, metabolic function, and host gut energy metabolism in aged mice.
Functional analysis and regulation mechanism of FGF19 on lipid metabolism in liver of large yellow croaker (Larimichthys crocea).
Baicalin attenuates pulmonary hypertension by targeting AMPK/CPT1A-mediated fatty acid metabolism.
Anti-Diabetic Effects of Ayanin, a Flavonoid Compound, in STZ/HFD-Induced Diabetic Mice by Upregulating GLUT4 and Suppressing Macrophage-Driven Inflammation in Adipose Tissues.
Lingguizhugan decoction improves cognitive impairment in APP/PS1 mice by promoting meningeal lymphatic drainage based on fatty acid degradation pathway.
Multi-omics analysis reveals that FABP2 suppresses colorectal cancer progression by regulating sphingomyelin metabolism via the PPAR signaling pathway.
ISG15 orchestrates dynamic crosstalk between mitochondrial fat oxidation and type 1 interferon in myeloid cells.
Integrated microbiota and metabolomic analysis demonstrates the growth-promoting effects of Lactobacillus plantarum in Nile tilapia (Oreochromis nilotica).
Effects of Piperine on Obese and Lean Nonalcoholic Fatty Liver Disease in Mice.
Cardiac PTN-SIRT1 axis alleviates oxidative stress and promotes mitochondrial energy reprogramming to mitigate doxorubicin-induced cardiotoxicity through AMPK/PGC1α signaling.
METTL5 promotes fatty acid metabolism by modulating peroxisome to induce hepatocellular carcinoma recurrence after thermal ablation.
Human FGF1(ΔHBS) Gene Therapy as Treatment for Metabolic Dysfunction-Associated Steatohepatitis in ApoE-KO Mice.
Diosgenin alleviates hepatic fibrosis via PI3K/Akt/mTOR mediated fatty acid metabolic reprogramming and NF-κB activation.
Fatty acid scavenging enables cancer escape from KRAS inhibition.
Dapagliflozin induces renal lipidomic remodeling and systemic metabolic improvement.
Astragaloside IV delays vascular aging by enhancing mitochondrial fatty acid β-oxidation via the MLXIPL-PPARα/PGC-1α axis.
Network toxicology and machine learning revealed the association between non-alcoholic fatty liver disease induced by polystyrene nanoplastics.
Palmitoyl-carnitine Regulates Lung Development by Promoting Pulmonary Mesenchyme Proliferation.
Aerobic exercise improved liver steatosis by modulating miR-34a-mediated PPARα/SIRT1-AMPK signaling pathway.
Hyodeoxycholic Acid Ameliorates Metabolic Syndrome Through Pathways of Primary Bile Acid Synthesis and Fatty Acid Degradation: Insights From a Rat Model.
Improved myocardial mitochondrial energy metabolism in rats with chronic heart failure by modifying fatty acid oxidation using an extract of sand-fired aconite (Jianchang gang processing).
Mechanistic insights into the PAI-1 inhibitor PAItrap3: enhancing lipid metabolism in adipose tissue of diabetic db/db mice.
FOXK2 regulates fatty acid metabolism and promotes cervical cancer progression by activating the mTOR/DRP1 signaling axis.
Reduction in within-litter variation of piglet birth weight through dietary supplementation of 3-hydroxyisobutyric acid in sows.
Chromatin remodeler BRD9 represses transcription of PPARα target genes, including CPT1A to suppress lipid metabolism.
Protective potential of bempedoic acid as an AMPK activator in tamoxifen-induced steatohepatitis in rats.
Selective and iron-independent ferroptosis in cancer cells induced by manipulation of mitochondrial fatty acid oxidation.
Cigarette smoke-induced PPAR signaling dysregulation accelerates Alzheimer's disease pathogenesis and cognitive decline in 5xFAD mice.
Mechanisms of metabolic-associated fatty liver disease induced by 48-week PCB138 exposure and theabrownin intervention.
Choline reduces inflammatory response and lipid accumulation in calf hepatocytes induced by NEFA via inhibiting ROS/ NF-κB/NLRP3 inflammasome axis.
Mitochondrial fatty acid oxidation dysfunction impairs autophagic flux through ATP deficiency-caused lysosomal pH abnormity.
Betaine decreases hepatic lipid deposition through DNA 5 mC and RNA m(6)A methylation-mediated regulation of fatty acid metabolic genes expression in laying hens.
Mitochondrial CCN1 drives ferroptosis via fatty acid β-oxidation.
Chronic Waterborne Exposure to Polystyrene Microplastics Induces Kupffer Cell Polarization Imbalance and Hepatic Lipid Accumulation.
Novel Pretreatment Autoantibodies Correlate with Enfortumab Vedotin-Related Dermatologic Events in Patients with Advanced Urothelial Cancer.
A galacturonan from sea buckthorn (Hippophae rhamnoides L.) berry modulates dyslipidemia by promoting hepatic lipolysis and mitochondrial oxidation.
PPARα activation attenuated heat-induced myocardial injury in mice.
Effect of rumen-protected guanidinoacetic acid provision as a dietary supplement on the growth, slaughter performance, and meat quality in simmental bulls.
Glia maturation factor-β deficiency improves insulin resistance by promoting CARM1-mediated lipid turnover.
TRIM34 inhibits triple-negative breast cancer progression by attenuating fatty acid synthesis via facilitating FASN ubiquitination.
ILF3 mediates lipid metabolism to promote pancreatic cancer development by regulating CPT1A-activated PPARa signaling pathway.
Network pharmacology and transcriptomics reveal complanatoside A regulates lipid metabolism in hyperlipidemia and nonalcoholic fatty liver disease via the AMPK pathway.
TRIM59 deficiency aggravates HFD-induced obesity in mice associated with increased adipose tissue inflammation, lipid accumulation, and apoptosis.
Fenofibrate alleviates sepsis-associated acute kidney injury by enhancing renal fatty acid oxidation.
MTCH2 modulates CPT1 activity to regulate lipid metabolism of adipocytes.
CPT1A inhibition alleviates plasmacytoid dendritic cell-mediated immune suppression in colon cancer through fatty acid oxidation modulation.
Salidroside improves bovine embryo quality by mitigating oxidative stress and regulating mitochondrial lipid metabolism.
Maternal exposure to high level of ursodeoxycholic acid during pregnancy promotes hepatic lipid deposition in the offspring by reducing the methylation level of Fasn gene.
Subacute exposure to thallium disrupts renal energy metabolism by impairing the function of subcellular organelles in aged mice of both sexes.
Syndecan-1 regulates lipid metabolism and mitigates fibrosis during the transition from acute kidney injury to chronic kidney disease.
The modulation of mTOR signaling on dietary carbohydrate utilization in largemouth bass (Micropterus salmoides).
Inflammation and Mitochondrial Dysfunction in Cirrhotic Cardiomyopathy: Therapeutic Implications.
NAT10-mediated lipid metabolic reprogramming drives EGFR-TKI resistance in non-small cell lung cancer via ac4C-dependent mRNA stabilization.
GSTK1 suppresses HCC aggravation via L-carnitine metabolism by PGAM5/DRP1 complex-mediated mitochondrial quality control.
Roseburia hominis enriched by baicalin reverses the non-response to metformin via upregulating linolenic acid metabolism.
Tau impedes glioma progression by enhancing fatty acid β-oxidation-induced cellular senescence.
Activation of TRPA1 prevents metabolic dysfunction-associated steatotic liver disease in diet-induced obese mice through stimulating the AMPK/CPT1A signaling pathway.
Aurantio-Obtusin Regulates Gut Microbiota and Serum Metabolism to Alleviate High-Fat Diet-Induced Obesity-Associated Non-Alcoholic Fatty Liver Disease in Mice.
AMPKα alleviates the inhibitory effect of NEFA on the function of bovine follicular granulosa cells cultured in vitro.
Steam explosion modified pea peptides alleviates hepatosteatosis by regulating lipid metabolism pathways and promoting autophagy.
LncRNA SNHG4 Regulates Lipid Metabolism and Inflammation in Non-Alcoholic Fatty Liver Disease by Targeting miR-34b-5p/XIAP Axis.
METTL3-Driven m6A Modification of Cpt1a Gene in High Fat Diet Related Liver Cancer Tumor Macrophages Facilitates Type II Macrophage Differentiation.
CPT1A/HIF-1α positive feedback loop induced fatty acid oxidation metabolic pathway contributes to the L-ascorbic acid-driven angiogenesis in breast cancer.
Dietary coconut oil lowered circulating fetuin-A levels and hepatic expression of fetuin-A in KK/TaJcl mice.
Alterations in PD-L1 succinylation shape anti-tumor immune responses in melanoma.
LncRNA Gm35585 transcriptionally activates the peroxidase EHHADH against diet-induced fatty liver.
The mediator subunit complex protein MED15 promotes lipid deposition and cancer progression during hypoxia.
Structural characterization of polysaccharides from Polygonatum Sibiricum and effect on alleviating hyperlipidemia in egg yolk emulsion-induced mice.
Meteorin-like protein alleviates intervertebral disc degeneration by suppressing lipid accumulation in nucleus pulposus cells via PPARα-CPT1A activation.
Parabacteroides distasonis promotes liver regeneration by increasing β-hydroxybutyric acid (BHB) production and BHB-driven STAT3 signals.
Qige Decoction attenuated non-alcoholic fatty liver disease through regulating SIRT6-PPARα-mediated fatty acid oxidation.
Impact of DNAH3 deficiency on sperm energy metabolism and motility leading to asthenozoospermia†.
Impaired fatty acid import or catabolism in macrophages restricts intracellular growth of Mycobacterium tuberculosis.
Membrane-associated ring-CH-type finger 2 protects against metabolic dysfunction-associated fatty liver disease by targeting fatty acid synthase.
Phosphatidylcholine Ameliorates Palmitic Acid-Induced Lipotoxicity by Facilitating Endoplasmic Reticulum and Mitochondria Contacts in Intervertebral Disc Degeneration.
Augmenting Macrophages Apoptosis Induced by Carnitine Palmitoyl Transferase 1A Inhibition via Acetyl-CoA-Associated Protein Acetylation.
Linghe granules reduces hepatic lipid accumulation in Non-alcoholic fatty liver disease through regulating lipid metabolism and redox balance.
Asprosin-FABP5 Interaction Modulates Mitochondrial Fatty Acid Oxidation through PPARα Contributing to MASLD Development.
Diallyl Trisulfide From Garlic Regulates RAB18 Phase Separation to Inhibit Lipophagy and Induce Cuproptosis in Hepatic Stellate Cells for Antifibrotic Effects.
Alisol B alleviates MASLD by activating liver autophagy and fatty acid oxidation via Ces2a.
Fatty Acid Oxidation Fuels Mitochondrial Respiration to Drive Epidermal Stem Cell Fate and Barrier Regeneration.
Alectinib and SALL4-Targeted Fatty Acid Oxidation: A Strategy to Combat Oxaliplatin Resistance in Gastric Cancer.
Alpha-synuclein mutations mislocalize cytoplasmic p300 compromising autophagy, which is rescued by ACLY inhibition.
Bavachin ameliorates cisplatin-induced nephrotoxicity by enhancing mitochondrial β-oxidation and lipid metabolism through MFN2.
Targeting EPAS-1/HIF-2α Pathway to Address Endocrine Resistance in Luminal A Type Breast Cancer.
OTUB1 enhances fatty acid oxidation in APAP-induced liver injury by mediating ACSL5 deubiquitination.
Anthraquinones of Cassiae Semen alleviate lipid accumulation in obesity by regulating brown adipose tissue and liver function.
Ultrasound-Guided Functionalized Extracellular Vesicles for Visualized, Controlled, and Efficient Renal Delivery for Enhanced Kidney Repair.
Hypoxia ameliorates high-fat-diet-induced hepatic lipid accumulation by modulating the HIF2α/PP4C signaling.
Early-life exercise extends healthspan but not lifespan in mice.
PRMT1-mediated methylation of UBE2m promoting calcium oxalate crystal-induced kidney injury by inhibiting fatty acid metabolism.
IGFBP1 orchestrates metabolic reprogramming to drive clear cell renal cell carcinoma progression through NR1H4-mediated lipid homeostasis disruption.
A lipid metabolism-related gene signature for risk stratification and prognosis prediction in patients with breast cancer.
Wenxia Changfu formula inhibits Lewis lung cancer metastasis by reprogramming tumor-associated macrophages through the PPAR-γ/CD36 pathway.
High-Fat Diet-Induced Diabetic Cardiomyopathy in Female Zebrafish: Cardiac Pathology and Functional Decline Mediated by Type 2 Diabetes.
Nicotinamide riboside promoted cardiac energetics and alleviated doxorubicin-induced cardiotoxicity via SIRT1/ERRα signal in human pluripotent stem cells-derived cardiomyocytes.
Fatty Acid Metabolism via CPT1A Supports Poll Gland Function and Rutting Activities in Male Bactrian Camels.
Citrus aurantium 'Changshan-huyou' physiological premature fruit drop: A promising prebiotic to tackle obesity.
Intermittent fasting triggers interorgan communication to suppress hair follicle regeneration.
Characteristics of different lipid droplet-mitochondrial contacts patterns during lipid droplet metabolism in T2DM-induced MASLD.
Autophagic flux-lipid droplet biogenesis cascade sustains mitochondrial fitness in colorectal cancer cells adapted to acidosis.
Sesamol Ameliorates Lipid Deposition by Maintaining the Integrity of the Lipid Droplet-Mitochondria Connection in Diabetic Nephropathy.
Moderate-intensity interval exercise exacerbates cardiac lipotoxicity in high-fat, high-calories diet-fed mice.
Impaired fatty acid import or catabolism in macrophages restricts intracellular growth of Mycobacterium tuberculosis.
The BET inhibitor JQ1 targets fat metabolism and counteracts obesity.
Isorhapontigenin alleviates acetaminophen-induced liver injury by promoting fatty acid oxidation.
Natural molecule isoliquiritigenin mitigates MASH and liver fibrosis in mice by promoting autophagy through the PI3K/Akt signaling pathway.
Trans 10, cis 12-conjugated linoleic acid in low concentration reduces while in high concentration enhances adipocyte metabolism but effectively improves hepatic steatosis of obese mice.
Succinylation enables IDE to act as a hub of larval tissue destruction and adult tissue reconstruction during insect metamorphosis.
Meteorin-like alleviates hepatic steatosis by regulating hepatic triglyceride secretion and fatty acid oxidation.
Vitisin A Outperforms Cyanidin-3-O-Glucoside in Triglyceride Reduction by Modulating Hepatic Lipogenesis and Fatty Acid β-Oxidation.
Ferulic acid from Angelica sinensis (Oliv.) Diels ameliorates lipid metabolism in alcoholic liver disease via AMPK/ACC and PI3K/AKT pathways.
PANAXADIOL SAPONIN ALLEVIATES LPS-INDUCED CARDIOMYOPATHY SIMILAR TO DEXAMETHASONE VIA IMPROVING MITOCHONDRIAL QUALITY CONTROL.
Kaili sour soup in alleviation of hepatic steatosis in rats via lycopene route: an experimental study.
Alpha Ketoglutaric Acid attenuates LPS Induced Inflammatory Response by Inhibiting the PKCε/MAPK/P65 Signaling Pathway and Inhibit Oxidative Stress in Kupffer Cells.
SIRT5 Facilitates Liver Steatosis Progression via Promoting SDH Desuccinylation During High-Fat Diet Feeding.
(-)-Guaiol Downregulates M2 Tumor-Associated Macrophage Polarization Through PPAR-γ Signaling to Suppress Lung Cancer.
Intestinal microbiota contributes to the heterogeneity of fat deposition by promoting mitochondrial fatty acid β-oxidation.
Riboflavin Increases Goat Sperm Motility via Enhancement of Mitochondrial β-Oxidation.
Machine learning-based identification of kbhb-affected tumor cell subsets as prognostic and therapeutic targets in breast cancer.
Knockdown of MiD49 and MiD51 alleviates collagen-induced arthritis and suppresses mitophagy and fatty acid oxidation (FAO) in rheumatoid arthritis fibroblast-like synoviocytes.
Genetic algorithm-back propagation artificial neural network model- and response surface methodology-based optimization of crude Lophatherum gracile Brongn. polysaccharides extraction and their anti-NAFLD effects via regulating liver-adipose tissue crosstalk.
Arachidonic acid metabolite prostaglandin E2 attenuates diethylhexyl phthalate-induced hepatotoxicity through promoting macrophage M2 polarization.
Inhibiting FAT1 Blocks Metabolic Bypass to Enhance Antitumor Efficacy of TCA Cycle Inhibition through Suppressing CPT1A-Dependent Fatty Acid Oxidation.
FGF21-MAPK1 Imbalance Disrupts Hepatic Lipid Metabolism in Dairy Cow Ketosis.
Inhibition of CPT1A activates the cGAS/STING pathway to enhance neutrophil-mediated tumor abrogation in triple-negative breast cancer.
Ergosterol from edible fungi: Enhancing fatty acid oxidation via CPT1A to protect against diabetic kidney disease.
Lactobacillus murinus alleviates insulin resistance via promoting L-citrulline synthesis.
Targeting Histone Deacetylase 11 with a Highly Selective Inhibitor for the Treatment of MASLD.
Distinct Hepatic Metabolic Reprogramming in Acute and Chronic Sleep Deprivation and the Protective Effects of the Chalcone Analogue TAK.
Inhibition Mechanism of Mulberry Prenylated Flavonoids Sanggenone D/Kuwanon G Against α-Glucosidase and the Regulation of Glucose via GLUT4 Pathway.
Pemafibrate modulates peroxisome proliferator-activated receptor alpha and prevents alcohol-associated liver disease in rats.
Cold-Induced DHRS4 Promotes Thermogenesis via Enhanced Fatty Acid β-Oxidation in Porcine Subcutaneous Adipocytes.
Artemether regulates liver glycogen and lipid utilization through mitochondrial pyruvate oxidation in db/db mice.
Bushen Huoxue formula attenuates lipid accumulation evoking excessive autophagy in premature ovarian insufficiency rats and palmitic acid-challenged KGN cells by modulating lipid metabolism.
Traditional Chinese Medicine formula Dai-Zong-Fang alleviating hepatic steatosis in db/db mice via gut microbiota modulation.
Palmitoylation of PKCδ by ZDHHC5 in hypothalamic microglia presents as a therapeutic target for fatty liver disease.
Identification of proteins related to SIS3 by iTRAQ and PRM-based comparative proteomic analysis in cisplatin-induced acute kidney injury.
Valine metabolite, 3-hydroxyisobutyrate, promotes lipid metabolism and cell proliferation in porcine mammary gland epithelial cells.
Inactivation of mitochondrial MUL1 E3 ubiquitin ligase deregulates mitophagy and prevents diet-induced obesity in mice.
Ethanol Extract of Propolis Attenuates Liver Lipid Metabolism Disorder in High-Fat Diet-Fed SAMP8 Mice.
ACAT1 suppresses clear cell renal cell carcinoma progression by AMPK mediated fatty acid metabolism.
Gentiopicroside ameliorates glucose and lipid metabolism in T2DM via targeting FGFR1.
The developmental pattern related to fatty acid uptake and oxidation in the yolk sac membrane and jejunum during embryogenesis in Muscovy duck.
NR2F2 Reactivation in Early-life Adipocyte Stem-like Cells Rescues Adipocyte Mitochondrial Oxidation.
Cpt1a Drives primed-to-naïve pluripotency transition through lipid remodeling.
Etomoxir repurposed as a promiscuous fatty acid mimetic chemoproteomic probe.
Clinopodium gracile Alleviates Metabolic Dysfunction-Associated Steatotic Liver Disease by Upregulating Peroxisome Proliferator-Activated Receptor α and Inhibiting Mitochondrial Oxidative Damage.
Hypothalamic SLC7A14 accounts for aging-reduced lipolysis in white adipose tissue of male mice.
FABP4 deficiency ameliorates alcoholic steatohepatitis in mice via inhibition of p53 signaling pathway.
Jujuboside A through YY1/CYP2E1 signaling alleviated type 2 diabetes-associated fatty liver disease by ameliorating hepatic lipid accumulation, inflammation, and oxidative stress.
Nicotinamide mononucleotide supplementation rescues mitochondrial and energy metabolism functions and ameliorates inflammatory states in the ovaries of aging mice.
Identification of serum metabolites associated with aristolochic acid nephropathy severity and insights into the underlying mechanism.
Dapagliflozin attenuates AKI to CKD transition in diabetes by activating SIRT3/PGC1-α signaling and alleviating aberrant metabolic reprogramming.
SMYD2 Promotes Calcium Oxalate-Induced Glycolysis in Renal Tubular Epithelial Cells via PTEN Methylation.
Berberine directly targets AKR1B10 protein to modulate lipid and glucose metabolism disorders in NAFLD.
Pea Albumin Alleviates Oleic Acid-Induced Lipid Accumulation in LO2 Cells Through Modulating Lipid Metabolism and Fatty Acid Oxidation Pathways.
MiR-21-3p inhibitor exerts myocardial protective effects by altering macrophage polarization state and reducing excessive mitophagy.
Oral Microbiome and CPT1A Function in Fatty Acid Metabolism in Oral Cancer.
Castration reshapes the liver by altering fatty acid composition and metabolism in male mice.
Rituximab induces ferroptosis and RSL3 overcomes rituximab resistance in diffuse large B-cell lymphoma cells.
The ZNF263/CPT1B axis regulates fatty acid β-oxidation to affect cisplatin resistance in lung adenocarcinoma.
HMGB1 Modulates Macrophage Metabolism and Polarization in Ulcerative Colitis by Inhibiting Cpt1a Expression.
Resistance Exercise Improves Glycolipid Metabolism and Mitochondrial Biogenesis in Skeletal Muscle of T2DM Mice via miR-30d-5p/SIRT1/PGC-1α Axis.
Deciphering Mechanisms of Adipocyte Differentiation in Abdominal Fat of Broilers.
Androgens exacerbate hepatic triglyceride accumulation in rats with polycystic ovary syndrome by downregulating MTTP expression.
A combined nanotherapeutic approach targeting farnesoid X receptor, ferroptosis, and fibrosis for nonalcoholic steatohepatitis treatment.
Probiotic-fermented tomato with hepatic lipid metabolism modulation effects: analysis of physicochemical properties, bioactivities, and potential bioactive compounds.
Transgenic female mice producing trans 10, cis 12-conjugated linoleic acid present excessive prostaglandin E2, adrenaline, corticosterone, glucagon, and FGF21.
APC/C-regulated CPT1C promotes tumor progression by upregulating the energy supply and accelerating the G1/S transition.
BNIP3 in hypoxia-induced mitophagy: Novel insights and promising target for non-alcoholic fatty liver disease.
Targeting carnitine palmitoyl transferase 1A (CPT1A) induces ferroptosis and synergizes with immunotherapy in lung cancer.
Targeting Erbin-mitochondria axis in platelets/megakaryocytes promotes B cell-mediated antitumor immunity.
Pennogenin 3-O-β-Chacotrioside Attenuates Hypertrophied Lipid Accumulation by Enhancing Mitochondrial Oxidative Capacity.
5-Heptadecylresorcinol Improves Aging-Associated Hepatic Fatty Acid Oxidation Dysfunction via Regulating Adipose Sirtuin 3.
Screening of CPT1A-Targeting Lipid Metabolism Modulators Using Mitochondrial Membrane Chromatography.
Testosterone regulates thymic remodeling by altering metabolic reprogramming in male rats.
miR-1268a Regulates Fatty Acid Metabolism by Targeting CD36 in Angiotensin II-induced Heart Failure.
Mechanistic of AMPK/ACC2 regulating myoblast differentiation by fatty acid oxidation of goat.
Deficiency of SDHC promotes metastasis by reprogramming fatty acid metabolism in colorectal cancer.
Chrysanthemum morifolium Ramat extract and probiotics combination ameliorates metabolic disorders through regulating gut microbiota and PPARα subcellular localization.
Penthorum chinense Pursh extract ameliorates alcohol-related fatty liver disease in mice via the SIRT1/AMPK signaling axis.
Redistribution of defective mitochondria-mediated dihydroorotate dehydrogenase imparts 5-fluorouracil resistance in colorectal cancer.
Tamoxifen upregulates the peroxisomal β-oxidation enzyme Enoyl CoA hydratase and 3-hydroxyacyl CoA hydratase ameliorating hepatic lipid accumulation in mice.
Regulation of astrocyte metabolism by mitochondrial translocator protein 18 kDa.
Luteolin alleviates cadmium-induced metabolism disorder through antioxidant and anti-inflammatory mechanisms in chicken kidney.
Lactobacillus rhamnosus NKU FL1-8 Isolated from Infant Feces Ameliorates the Alcoholic Liver Damage by Regulating the Gut Microbiota and Intestinal Barrier in C57BL/6J Mice.
Structural Variances in Curcumin Degradants: Impact on Obesity in Mice.
CPT1A loss disrupts BCAA metabolism to confer therapeutic vulnerability in TP53-mutated liver cancer.
Ginsenoside Rb1 regulates CPT1A deacetylation to inhibit intramuscular fat infiltration after rotator cuff tear.
Hypoxia induces mitochondrial protein lactylation to limit oxidative phosphorylation.
Effects of hazelnut soluble dietary fiber on lipid-lowering and gut microbiota in high-fat-diet-fed rats.
Prunella vulgaris L. attenuates gut dysbiosis and endotoxin leakage against alcoholic liver disease.
Endogenous Coriobacteriaceae enriched by a high-fat diet promotes colorectal tumorigenesis through the CPT1A-ERK axis.
Exploring the mechanism and phytochemicals in Psoraleae Fructus-induced hepatotoxicity based on RNA-seq, in vitro screening and molecular docking.
Acetyl-CoA synthetase 2 promotes diabetic renal tubular injury in mice by rewiring fatty acid metabolism through SIRT1/ChREBP pathway.
Hypoxia induced cell dormancy of salivary adenoid cystic carcinoma through miR-922/DEC2 axis.
FXR overexpression prevents hepatic steatosis through inhibiting AIM2 inflammasome activation in alcoholic liver disease.
ACACA reduces lipid accumulation through dual regulation of lipid metabolism and mitochondrial function via AMPK- PPARα- CPT1A axis.
Mitochondrial apolipoprotein MIC26 is a metabolic rheostat regulating central cellular fuel pathways.
Chlorogenic acid alleviates renal fibrosis by reducing lipid accumulation in diabetic kidney disease through suppressing the Notch1 and Stat3 signaling pathway.
Attenuation of high-fat diet-induced weight gain by apolipoprotein A4.
Sirt1-mediated deacetylation of PGC-1α alleviated hepatic steatosis in type 2 diabetes mellitus via improving mitochondrial fatty acid oxidation.
N6-methyladenosine regulates metabolic remodeling in kidney aging through transcriptional regulator GLIS1.
N1-methyladenosine RNA methylation patterns are associated with an increased risk to biochemical recurrence in prostate cancer and serve as a potential novel biomarker for patient stratification.
Carnitine palmitoyltransferase 1 facilitates fatty acid oxidation in a non-cell-autonomous manner.
Protective Effects of Dioscin and Diosgenin on Plateau Hyperuricemia by Attenuating Renal Inflammation via EPHX2.
CD9 Counteracts Liver Steatosis and Mediates GCGR Agonist Hepatic Effects.
CircHIPK3/miR-124 affects angiogenesis in early-onset preeclampsia via CPT1A-mediated fatty acid oxidation.
Regulatory effect of β-glucan secreted by Rhizobium pusense on triglyceride metabolism and their relationships with the modulation of intestinal microbiota in mice fed a high-fat diet.
Cryptotanshinone alleviates liver fibrosis via inhibiting STAT3/CPT1A-dependent fatty acid oxidation in hepatic stellate cells.
Moderate replacement of fish oil with palmitic acid-stimulated mitochondrial fusion promotes β-oxidation by Mfn2 interacting with Cpt1α via its GTPase-domain.
Targeting hepatic ceruloplasmin mitigates nonalcoholic steatohepatitis by modulating bile acid metabolism.
Beneficial Effects of High-Intensity Interval Training and Dietary Changes Intervention on Hepatic Fat Accumulation in HFD-Induced Obese Rats.
C6orf15 promotes liver metastasis via WNT/β-catenin signalling in colorectal cancer.
Complexes of Soluble Dietary Fiber and Polyphenols from Lotus Root Regulate High-Fat Diet-Induced Hyperlipidemia in Mice.
Herpetrione, a New Type of PPARα Ligand as a Therapeutic Strategy Against Nonalcoholic Steatohepatitis.
Loss of PPARα function promotes epigenetic dysregulation of lipid homeostasis driving ferroptosis and pyroptosis lipotoxicity in metabolic dysfunction associated Steatotic liver disease (MASLD).
Dihydroartemisinin Potentiates VEGFR-TKIs Antitumorigenic Effect on Osteosarcoma by Regulating Loxl2/VEGFA Expression and Lipid Metabolism Pathway.
Dapagliflozin alleviates renal fibrosis in a mouse model of adenine-induced renal injury by inhibiting TGF-β1/MAPK mediated mitochondrial damage.
FDXR drives primary and endocrine-resistant tumor cell growth in ER+ breast cancer via CPT1A-mediated fatty acid oxidation.
Berberine alleviates non-alcoholic hepatic steatosis partially by promoting SIRT1 deacetylation of CPT1A in mice.
Sustained IP3-linked Ca(2+) signaling promotes progression of triple negative breast cancer cells by regulating fatty acid metabolism.
Double-edged effect of sodium citrate in Nile tilapia (Oreochromis niloticus): Promoting lipid and protein deposition vs. causing hyperglycemia and insulin resistance.
γ-glutamylcysteine alleviates insulin resistance and hepatic steatosis by regulating adenylate cyclase and IGF-1R/IRS1/PI3K/Akt signaling pathways.
Metabolic characteristics of voriconazole - Induced liver injury in rats.
Hepatic conversion of acetyl-CoA to acetate plays crucial roles in energy stress.
Chlorogenic Acid from Burdock Roots Ameliorates Oleic Acid-Induced Steatosis in HepG2 Cells through AMPK/ACC/CPT-1 Pathway.
WTAP boosts lipid oxidation and induces diabetic cardiac fibrosis by enhancing AR methylation.
Metabolic and functional remodeling of colonic macrophages in response to high-fat diet-induced obesity.
C3aR Antagonist Alleviates C3a Induced Tubular Profibrotic Phenotype Transition via Restoring PPARα/CPT-1α Mediated Mitochondrial Fatty Acid Oxidation in Renin-Dependent Hypertension.
Korean red ginseng formula attenuates non-alcoholic fatty liver disease in oleic acid-induced HepG2 cells and high-fat diet-induced rats.
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Voltage-dependent anion channel 1 (VDAC1) overexpression alleviates cardiac fibroblast activation in cardiac fibrosis via regulating fatty acid metabolism.
Chitobiose exhibited a lipid-lowering effect in ob/ob(-/-) mice via butyric acid enrolled liver-gut crosstalk.
PBRM1 mutation and WDR72 expression as potential combinatorial biomarker for predicting the response to Nivolumab in patients with ccRCC: a tumor marker prognostic study.
Lactoferrin Alleviates Ethanol-Induced Injury via Promoting Nrf2 Nuclear Translocation in BRL-3A Rat Liver Cells.
Resensitizing Paclitaxel-Resistant Ovarian Cancer via Targeting Lipid Metabolism Key Enzymes CPT1A, SCD and FASN.
Calponin 2 harnesses metabolic reprogramming to determine kidney fibrosis.
Organelle interactions compartmentalize hepatic fatty acid trafficking and metabolism.
L-carnitine alleviates synovitis in knee osteoarthritis by regulating lipid accumulation and mitochondrial function through the AMPK-ACC-CPT1 signaling pathway.
Apolipoprotein A4 Elevates Sympathetic Activity and Thermogenesis in Male Mice.
Vinyl chloride enhances high-fat diet-induced proteome alterations in the mouse pancreas related to metabolic dysfunction.
Metrnl Alleviates Lipid Accumulation by Modulating Mitochondrial Homeostasis in Diabetic Nephropathy.
Developmental changes in lipid and fatty acid metabolism and the inhibition by in ovo feeding oleic acid in Muscovy duck embryogenesis.
Complementary hepatic metabolomics and proteomics reveal the adaptive mechanisms of dairy cows to the transition period.
CPT1A modulates PI3K/Akt/mTOR pathway to promote preeclampsia.
Extraction, characterization, and anti-nonalcoholic steatohepatitis activity of a (1,3) (1,6)-β-D-glucan from the Polyporus umbellatus (Pers.) Fries.
Mettl3-mediated m(6)A modification plays a role in lipid metabolism disorders and progressive liver damage in mice by regulating lipid metabolism-related gene expression.
Human umbilical cord mesenchymal stem cell-derived exosomes ameliorate liver steatosis by promoting fatty acid oxidation and reducing fatty acid synthesis.
Changes to PUFA-PPAR pathway during mesaconitine induced myocardial coagulative necrosis.
Cassiae Semen improves non-alcoholic fatty liver disease through autophagy-related pathway.
Modulation of the Microbiome-Fat-Liver Axis by Lactic Acid Bacteria: A Potential Alleviated Role in High-Fat-Diet-Induced Obese Mice.
High-intensity interval training induces renal injury and fibrosis in type 2 diabetic mice.
Hepatic DKK1-driven steatosis is CD36 dependent.
Sclareol ameliorates liver injury by inhibiting nuclear factor-kappa B/NOD-like receptor protein 3-mediated inflammation and lipid metabolism disorder in diabetic mice.
Ketogenic Diet Combined with Moderate Aerobic Exercise Training Ameliorates White Adipose Tissue Mass, Serum Biomarkers, and Hepatic Lipid Metabolism in High-Fat Diet-Induced Obese Mice.
Dietary l-carnitine regulates liver lipid metabolism via simultaneously activating fatty acid β-oxidation and suppressing endoplasmic reticulum stress in large yellow croaker fed with high-fat diets.
PPARα agonist fenofibrate prevents postoperative cognitive dysfunction by enhancing fatty acid oxidation in mice.
Gene therapy targeting miR‑212‑3p exerts therapeutic effects on MAFLD similar to those of exercise.
High cholesterol intake remodels cholesterol turnover and energy homeostasis in Nile tilapia (Oreochromis niloticus).
Malonyl-CoA Accumulation as a Compensatory Cytoprotective Mechanism in Cardiac Cells in Response to 7-Ketocholesterol-Induced Growth Retardation.
Is There a Role of Warburg Effect in Prostate Cancer Aggressiveness? Analysis of Expression of Enzymes of Lipidic Metabolism by Immunohistochemistry in Prostate Cancer Patients (DIAMOND Study).
Repair of airway epithelia requires metabolic rewiring towards fatty acid oxidation.
SIRT3 promotes metabolic maturation of human iPSC-derived cardiomyocytes via OPA1-controlled mitochondrial dynamics.
STAT6 promoting oxalate crystal deposition-induced renal fibrosis by mediating macrophage-to-myofibroblast transition via inhibiting fatty acid oxidation.
Exploratory metabolomic analysis based on UHPLC-Q-TOF-MS/MS to study hypoxia-reoxygenation energy metabolic alterations in HK-2 cells.
Mitochondrial dysfunction and endoplasmic reticulum stress induced by activation of PPARα leaded testicular to apoptosis in SD rats explored to di-(2-ethylhexyl) phthalate (DEHP).
Stimulator of interferon genes promotes diabetic sarcopenia by targeting peroxisome proliferator activated receptors γ degradation and inhibiting fatty acid oxidation.
Berberine ameliorates renal interstitial inflammation and fibrosis in mice with unilateral ureteral obstruction.
m6A-Modified circTET2 Interacting with HNRNPC Regulates Fatty Acid Oxidation to Promote the Proliferation of Chronic Lymphocytic Leukemia.
Aberrant centrosome biogenesis disrupts nephron and collecting duct progenitor growth and fate resulting in fibrocystic kidney disease.
α-Lactalbumin Peptide Asp-Gln-Trp Ameliorates Hepatic Steatosis and Oxidative Stress in Free Fatty Acids-Treated HepG2 Cells and High-Fat Diet-Induced NAFLD Mice by Activating the PPARα Pathway.
SIRT6 regulates obesity-induced oxidative stress via ENDOG/SOD2 signaling in the heart.
Novel treatment and insight for irradiation-induced injuries: Dibucaine ameliorates irradiation-induced testicular injury by inhibiting fatty acid oxidation in primary Leydig cells.
Melatonin alleviates cadmium-induced nonalcoholic fatty liver disease in ducks by alleviating autophagic flow arrest via PPAR-α and reducing oxidative stress.
Inhibition of pyruvate carboxylase reverses metformin resistance by activating AMPK in pancreatic cancer.
Cordycepin reprogramming lipid metabolism to block metastasis and EMT via ERO1A/mTOR/SREBP1 axis in cholangiocarcinoma.
Inhibition of Fatty Acid β-Oxidation by Fatty Acid Binding Protein 4 Induces Ferroptosis in HK2 Cells Under High Glucose Conditions.
Protopanaxadiol ameliorates NAFLD by regulating hepatocyte lipid metabolism through AMPK/SIRT1 signaling pathway.
Saturated fatty acids increase LPI to reduce FUNDC1 dimerization and stability and mitochondrial function.
RASAL2 Deficiency Attenuates Hepatic Steatosis by Promoting Hepatic VLDL Secretion via the AKT/TET1/MTTP Axis.
Distinct Transcriptional Responses of Skeletal Muscle to Short-Term Cold Exposure in Tibetan Pigs and Bama Pigs.
G-protein coupled receptor 19 (GPR19) knockout mice display sex-dependent metabolic dysfunction.
Aged green tea reduces high-fat diet-induced fat accumulation and inflammation via activating the AMP-activated protein kinase signaling pathway.
The Adaptive Characteristics of Cholesterol and Bile Acid Metabolism in Nile Tilapia Fed a High-Fat Diet.
Disturbance of Fatty Acid Metabolism Promoted Vascular Endothelial Cell Senescence via Acetyl-CoA-Induced Protein Acetylation Modification.
The GR-gp78 Pathway is involved in Hepatic Lipid Accumulation Induced by Overexpression of 11β-HSD1.
Atractylenolide III ameliorates Non-Alcoholic Fatty Liver Disease by activating Hepatic Adiponectin Receptor 1-Mediated AMPK Pathway.
Liver-specific overexpression of lipoprotein lipase improves glucose metabolism in high-fat diet-fed mice.
Canagliflozin Attenuates Hepatic Steatosis and Atherosclerosis Progression in Western Diet-Fed ApoE-Knockout Mice.
The effects of gut microbiota colonizing on the porcine hypothalamus revealed by whole transcriptome analysis.
D-Mannose Regulates Hepatocyte Lipid Metabolism via PI3K/Akt/mTOR Signaling Pathway and Ameliorates Hepatic Steatosis in Alcoholic Liver Disease.
Sleeve Gastrectomy-Induced AMPK Activation Attenuates Diabetic Cardiomyopathy by Maintaining Mitochondrial Homeostasis via NR4A1 Suppression in Rats.
Atorvastatin Restores PPARα Inhibition of Lipid Metabolism Disorders by Downregulating miR-21 Expression to Improve Mitochondrial Function and Alleviate Diabetic Nephropathy Progression.
Imbalance hepatic metabolism homeostasis in the F1 generation of endometrial DNMT3B conditional knockout female mice.
Mitochondrial STAT3 exacerbates LPS-induced sepsis by driving CPT1a-mediated fatty acid oxidation.
CD147 Mediates 5-Fluorouracil Resistance in Colorectal Cancer by Reprogramming Glycolipid Metabolism.
PTPRO represses colorectal cancer tumorigenesis and progression by reprogramming fatty acid metabolism.
Metabolic Syndrome Ameliorated by 4-Methylesculetin by Reducing Hepatic Lipid Accumulation.
Transcriptomic responses are sex-dependent in the skeletal muscle and liver in offspring of obese mice.
The HSF1-CPT1a Pathway Is Differentially Regulated in NAFLD Progression.
WY-14643 attenuates lipid deposition via activation of the PPARα/CPT1A axis by targeting Gly335 to inhibit cell proliferation and migration in ccRCC.
Maternal high-fructose corn syrup consumption causes insulin resistance and hyperlipidemia in offspring via DNA methylation of the Pparα promoter region.
Piperine Improves Lipid Dysregulation by Modulating Circadian Genes Bmal1 and Clock in HepG2 Cells.
SIRT1 prevents cigarette smoking-induced lung fibroblasts activation by regulating mitochondrial oxidative stress and lipid metabolism.
The Ameliorating Effects of Apple Polyphenol Extract on High-Fat-Diet-Induced Hepatic Steatosis Are SIRT1-Dependent: Evidence from Hepatic-Specific SIRT1 Heterozygous Mutant C57BL/6 Mice.
A roadmap for the characterization of energy metabolism in human cardiomyocytes derived from induced pluripotent stem cells.
In vitro absorption and lipid-lowering activity of baicalin esters synthesized by whole-cell catalyzed esterification.
Highland barley Monascus purpureus Went extract ameliorates high-fat, high-fructose, high-cholesterol diet induced nonalcoholic fatty liver disease by regulating lipid metabolism in golden hamsters.
Psoralen Suppresses Lipid Deposition by Alleviating Insulin Resistance and Promoting Autophagy in Oleate-Induced L02 Cells.
Short-term intermittent cigarette smoke exposure enhances alveolar type 2 cell stemness via fatty acid oxidation.
Increased fatty acid metabolism attenuates cardiac resistance to β-adrenoceptor activation via mitochondrial reactive oxygen species: A potential mechanism of hypoglycemia-induced myocardial injury in diabetes.
Inhibition of Fatty Acid Translocase (FAT/CD36) Palmitoylation Enhances Hepatic Fatty Acid β-Oxidation by Increasing Its Localization to Mitochondria and Interaction with Long-Chain Acyl-CoA Synthetase 1.
Diallyl disulfide ameliorates ethanol-induced liver steatosis and inflammation by maintaining the fatty acid catabolism and regulating the gut-liver axis.
Transcriptome Comparison Reveals the Difference in Liver Fat Metabolism between Different Sheep Breeds.
PP1A prevents ROS-induced pyroptosis by inhibiting MAPK/caspase-3 in mouse adipose tissue.
Exercise promotes angiogenesis by enhancing endothelial cell fatty acid utilization via liver-derived extracellular vesicle miR-122-5p.
Overexpression of carnitine palmitoyltransferase 1A promotes mitochondrial fusion and differentiation of glioblastoma stem cells.
Endurance exercise-mediated metabolic reshuffle attenuates high-caloric diet-induced non-alcoholic fatty liver disease.
Lactoferrin Prevents Chronic Alcoholic Injury by Regulating Redox Balance and Lipid Metabolism in Female C57BL/6J Mice.
Nutritional programming of large yellow croaker (Larimichthys crocea) larvae by dietary vegetable oil: effects on growth performance, lipid metabolism and antioxidant capacity.
Constituents of Morus alba var. multicaulis leaf improve lipid metabolism by activating the AMPK signaling pathway in HepG2 cells.
Chronic angiotensin receptor activation promotes hepatic triacylglycerol accumulation during an acute glucose challenge in obese-insulin-resistant OLETF rats.
Targeting Cpt1a-Bcl-2 interaction modulates apoptosis resistance and fibrotic remodeling.
Enhancement of Acylcarnitine Levels in Small Intestine of Abdominal Irradiation Rats Might Relate to Fatty Acid β-Oxidation Pathway Disequilibration.
Gestational bisphenol A exposure impairs hepatic lipid metabolism by altering mTOR/CRTC2/SREBP1 in male rat offspring.
Steatosis induced by nonylphenol in HepG2 cells and the intervention effect of curcumin.
Dopamine receptor D1 signaling stimulates lipolysis and browning of white adipocytes.
Isoliquiritigenin-mediated miR-23a-3p inhibition activates PGC-1α to alleviate alcoholic liver injury.
Mildronate triggers growth suppression and lipid accumulation in largemouth bass (Micropterus salmoides) through disturbing lipid metabolism.
Activation of PGC-1α via isoliquiritigenin-induced downregulation of miR-138-5p alleviates nonalcoholic fatty liver disease.
Ginsenoside CK ameliorates hepatic lipid accumulation via activating the LKB1/AMPK pathway in vitro and in vivo.
FUS Mutation Causes Disordered Lipid Metabolism in Skeletal Muscle Associated with ALS.
Ethanolic extract of root from Arctium lappa L ameliorates obesity and hepatic steatosis in rats by regulating the AMPK/ACC/CPT-1 pathway.
Hif-2α regulates lipid metabolism in alcoholic fatty liver disease through mitophagy.
A novel small compound TOIDC suppresses lipogenesis via SREBP1-dependent signaling to curb MAFLD.
Neutrophil trafficking to the site of infection requires Cpt1a-dependent fatty acid β-oxidation.
MPYS Modulates Fatty Acid Metabolism and Immune Tolerance at Homeostasis Independent of Type I IFNs.
Elevated thyroid hormones caused by high concentrate diets participate in hepatic metabolic disorders in dairy cows.
Metabolic reprogramming from glycolysis to fatty acid uptake and beta-oxidation in platinum-resistant cancer cells.
CRIP1 suppresses BBOX1-mediated carnitine metabolism to promote stemness in hepatocellular carcinoma.
Ketogenesis acts as an endogenous protective programme to restrain inflammatory macrophage activation during acute pancreatitis.
The activation of PPARγ enhances Treg responses through up-regulating CD36/CPT1-mediated fatty acid oxidation and subsequent N-glycan branching of TβRII/IL-2Rα.
L-theanine prevents progression of nonalcoholic hepatic steatosis by regulating hepatocyte lipid metabolic pathways via the CaMKKβ-AMPK signaling pathway.
Succinylation Regulators Promote Clear Cell Renal Cell Carcinoma by Immune Regulation and RNA N6-Methyladenosine Methylation.
Dendrobium officinale Regulates Fatty Acid Metabolism to Ameliorate Liver Lipid Accumulation in NAFLD Mice.
Recombinant Human Growth Hormone Inhibits Lipotoxicity, Oxidative Stress, and Apoptosis in a Mouse Model of Diabetic Cardiomyopathy.
ZLN005 protects against ischemia-reperfusion-induced kidney injury by mitigating oxidative stress through the restoration of mitochondrial fatty acid oxidation.
Activation of TAF9 via Danshensu-Induced Upregulation of HDAC1 Expression Alleviates Non-alcoholic Fatty Liver Disease.
High-Salt Attenuates the Efficacy of Dapagliflozin in Tubular Protection by Impairing Fatty Acid Metabolism in Diabetic Kidney Disease.
Endoplasmic Reticulum Stress Disturbs Lipid Homeostasis and Augments Inflammation in the Intestine and Isolated Intestinal Cells of Large Yellow Croaker (Larimichthys crocea).
Mitofusin 2 Deficiency Causes Pro-Inflammatory Effects in Human Primary Macrophages.
Antiproliferative, Antiangiogenic, and Antimetastatic Therapy Response by Mangiferin in a Syngeneic Immunocompetent Colorectal Cancer Mouse Model Involves Changes in Mitochondrial Energy Metabolism.
Lysosome-Dependent LXR and PPARδ Activation Upon Efferocytosis in Human Macrophages.
Effects of High Levels of Dietary Linseed Oil on the Growth Performance, Antioxidant Capacity, Hepatic Lipid Metabolism, and Expression of Inflammatory Genes in Large Yellow Croaker (Larimichthys crocea).
Daily Dose of Bovine Lactoferrin Prevents Ethanol-Induced Liver Injury and Death in Male Mice by Regulating Hepatic Alcohol Metabolism and Modulating Gut Microbiota.
Pterostilbene attenuates RIPK3-dependent hepatocyte necroptosis in alcoholic liver disease via SIRT2-mediated NFATc4 deacetylation.
CPT1A and fatty acid β-oxidation are essential for tumor cell growth and survival in hormone receptor-positive breast cancer.
Live Combined B. subtilis and E. faecium Alleviate Liver Inflammation, Improve Intestinal Barrier Function, and Modulate Gut Microbiota in Mice with Non-Alcoholic Fatty Liver Disease.
Exposure to ethephon compromises endometrial decidualization in mice during early pregnancy via GPR120.
Dihydroartemisinin regulates lipid droplet metabolism in hepatic stellate cells by inhibiting lncRNA-H19-induced AMPK signal.
Bioactive flavonoids and stilbenes from the leaf of Morus alba var. multicaulis.
PGC1α-Mediated Metabolic Reprogramming Drives the Stemness of Pancreatic Precursor Lesions.
Sex-specific genetic regulation of adipose mitochondria and metabolic syndrome by Ndufv2.
The modified mitochondrial outer membrane carrier MTCH2 links mitochondrial fusion to lipogenesis.
High-fat diet-induced obesity primes fatty acid β-oxidation impairment and consequent ovarian dysfunction during early pregnancy.
Danthron ameliorates obesity and MAFLD through activating the interplay between PPARα/RXRα heterodimer and adiponectin receptor 2.
Simultaneously targeting SOAT1 and CPT1A ameliorates hepatocellular carcinoma by disrupting lipid homeostasis.
Apple polyphenol extract alleviates lipid accumulation in free-fatty-acid-exposed HepG2 cells via activating autophagy mediated by SIRT1/AMPK signaling.
Glioma cells survival depends both on fatty acid oxidation and on functional carnitine transport by SLC22A5.
FGF1(ΔHBS) prevents diabetic cardiomyopathy by maintaining mitochondrial homeostasis and reducing oxidative stress via AMPK/Nur77 suppression.
Effect of selenium-enriched kiwifruit on body fat reduction and liver protection in hyperlipidaemic mice.
Icaritin ameliorates hepatic steatosis via promoting fatty acid β-oxidation and insulin sensitivity.
Marein ameliorates Ang II/hypoxia-induced abnormal glucolipid metabolism by modulating the HIF-1α/PPARα/γ pathway in H9c2 cells.
Deficiency of Mitochondrial Glycerol 3-Phosphate Dehydrogenase Exacerbates Podocyte Injury and the Progression of Diabetic Kidney Disease.
Carbohydrate response element-binding protein regulates lipid metabolism via mTOR complex1 in diabetic nephropathy.
Skip participates in formation and lipid metabolism of beige adipose and might mediate the effects of SIRT1 activator BTM-0512 on beige remodeling.
Proteomic Analysis Reveals the Effect of Trichostatin A and Bone Marrow-Derived Dendritic Cells on the Fatty Acid Metabolism of NIH3T3 Cells under Oxygen-Glucose Deprivation Conditions.
Cordycepin attenuates high-fat diet-induced non-alcoholic fatty liver disease via down-regulation of lipid metabolism and inflammatory responses.
Single Mutation in the NFU1 Gene Metabolically Reprograms Pulmonary Artery Smooth Muscle Cells.
Roles of acyl-CoA synthetase long-chain family member 5 and colony stimulating factor 2 in inhibition of palmitic or stearic acids in lung cancer cell proliferation and metabolism.
HRD1 inhibits fatty acid oxidation and tumorigenesis by ubiquitinating CPT2 in triple-negative breast cancer.
Gentisic acid prevents diet-induced obesity in mice by accelerating the thermogenesis of brown adipose tissue.
18β-glycyrrhetinic acid improves high-intensity exercise performance by promoting glucose-dependent energy production and inhibiting oxidative stress in mice.
NMR-based untargeted metabolomics approach to investigate the systemic lipid metabolism regulation of norisoboldine in collagen-induced arthritis rats.
Carnitine Palmitoyltransferase 1 Regulates Prostate Cancer Growth under Hypoxia.
FXR, a Key Regulator of Lipid Metabolism, Is Inhibited by ER Stress-Mediated Activation of JNK and p38 MAPK in Large Yellow Croakers (Larimichthys crocea) Fed High Fat Diets.
GEO data mining and TCGA analysis reveal altered branched chain amino acid metabolism in pancreatic cancer patients.
Echinacoside improves diabetic liver injury by regulating the AMPK/SIRT1 signaling pathway in db/db mice.
The Role of GPR109a Signaling in Niacin Induced Effects on Fed and Fasted Hepatic Metabolism.
Tributyrin Inhibits Ethanol-Induced Epigenetic Repression of CPT-1A and Attenuates Hepatic Steatosis and Injury.
Mogroside V Protects against Hepatic Steatosis in Mice on a High-Fat Diet and LO2 Cells Treated with Free Fatty Acids via AMPK Activation.
Mild Hypothermia Attenuates Hepatic Ischemia-Reperfusion Injury through Regulating the JAK2/STAT3-CPT1a-Dependent Fatty Acid β-Oxidation.
TET1 promotes fatty acid oxidation and inhibits NAFLD progression by hydroxymethylation of PPARα promoter.
Effects of canagliflozin on growth and metabolic reprograming in hepatocellular carcinoma cells: Multi-omics analysis of metabolomics and absolute quantification proteomics (iMPAQT).
UCHL1 regulates oxidative activity in skeletal muscle.
Fenofibrate-induced mitochondrial dysfunction and metabolic reprogramming reversal: the anti-tumor effects in gastric carcinoma cells mediated by the PPAR pathway.
High-Intensity Interval Training Restores Glycolipid Metabolism and Mitochondrial Function in Skeletal Muscle of Mice With Type 2 Diabetes.
Critical biomarkers for myocardial damage by fine particulate matter: Focused on PPARα-regulated energy metabolism.
Sirtuin 3-mediated deacetylation of acyl-CoA synthetase family member 3 by protocatechuic acid attenuates non-alcoholic fatty liver disease.
SGLT2 Inhibition Mediates Protection from Diabetic Kidney Disease by Promoting Ketone Body-Induced mTORC1 Inhibition.
Uncovering the mechanism of Astragali Radix against nephrotic syndrome by intergrating lipidomics and network pharmacology.
Peroxisomal proliferator-activated receptor α-b deficiency induces the reprogramming of nutrient metabolism in zebrafish.
Protective effect of Yi-Qi-Huo-Xue Decoction against ischemic heart disease by regulating cardiac lipid metabolism.
A substrate-trapping strategy to find E3 ubiquitin ligase substrates identifies Parkin and TRIM28 targets.
A novel bile acid analog, A17, ameliorated non-alcoholic steatohepatitis in high-fat diet-fed hamsters.
Effect and mechanism of ginsenoside Rg1-regulating hepatic steatosis in HepG2 cells induced by free fatty acid.
Melanoma Persister Cells Are Tolerant to BRAF/MEK Inhibitors via ACOX1-Mediated Fatty Acid Oxidation.
CPT1A Over-Expression Increases Reactive Oxygen Species in the Mitochondria and Promotes Antioxidant Defenses in Prostate Cancer.
RIPK3 Orchestrates Fatty Acid Metabolism in Tumor-Associated Macrophages and Hepatocarcinogenesis.
Sirt3 modulates fatty acid oxidation and attenuates cisplatin-induced AKI in mice.
Modulation of SIRT1-mediated signaling cascades in the liver contributes to the amelioration of nonalcoholic steatohepatitis in high fat fed middle-aged LDL receptor knockout mice by dihydromyricetin.
Yin Zhi Huang, a traditional Chinese herbal formula, ameliorates diet-induced obesity and hepatic steatosis by activating the AMPK/SREBP-1 and the AMPK/ACC/CPT1A pathways.
Low Expression of Sirtuin 1 in the Dairy Cows with Mild Fatty Liver Alters Hepatic Lipid Metabolism.
Prohibitin 2 deficiency impairs cardiac fatty acid oxidation and causes heart failure.
Severe hypoglycemia exacerbates myocardial dysfunction and metabolic remodeling in diabetic mice.
Hepatic HuR modulates lipid homeostasis in response to high-fat diet.
Identification of FABP5 as an immunometabolic marker in human hepatocellular carcinoma.
Spexin protects cardiomyocytes from hypoxia-induced metabolic and mitochondrial dysfunction.
Flavonoids extracted from mulberry (Morus alba L.) leaf improve skeletal muscle mitochondrial function by activating AMPK in type 2 diabetes.
Hepatic Synaptotagmin 1 is involved in the remodelling of liver plasma- membrane lipid composition and gene expression in male Apoe-deficient mice consuming a Western diet.
Targeting Fat Oxidation in Mouse Prostate Cancer Decreases Tumor Growth and Stimulates Anti-Cancer Immunity.
Dynamic Cardiolipin Synthesis Is Required for CD8(+) T Cell Immunity.
Hypertensive Rats Treated Chronically With N(ω)-Nitro-L-Arginine Methyl Ester (L-NAME) Induced Disorder of Hepatic Fatty Acid Metabolism and Intestinal Pathophysiology.
UPLC-QTOF/MS-based metabolomics analysis of plasma reveals an effect of Xue-Fu-Zhu-Yu capsules on blood-stasis syndrome in CHD rats.
Lin28 enhances de novo fatty acid synthesis to promote cancer progression via SREBP-1.
The contrary intracellular and extracellular functions of PEDF in HCC development.
Apple Polyphenol Extract Alleviates High-Fat-Diet-Induced Hepatic Steatosis in Male C57BL/6 Mice by Targeting LKB1/AMPK Pathway.
Loss of ubiquitin-conjugating enzyme E2 (Ubc9) in macrophages exacerbates multiple low-dose streptozotocin-induced diabetes by attenuating M2 macrophage polarization.
Regulation effects of rosemary (Rosmarinus officinalis Linn.) on hepatic lipid metabolism in OA induced NAFLD rats.
Role of ketone signaling in the hepatic response to fasting.
Integrated Metabolomics and Lipidomics Analyses Reveal Metabolic Reprogramming in Human Glioma with IDH1 Mutation.
MSC-regulated lncRNA MACC1-AS1 promotes stemness and chemoresistance through fatty acid oxidation in gastric cancer.
Impairment of Fatty Acid Oxidation in Alveolar Epithelial Cells Mediates Acute Lung Injury.
Coenzyme Q10 attenuates high-fat diet-induced non-alcoholic fatty liver disease through activation of the AMPK pathway.
Fe(3)O(4)@OA@Poloxamer nanoparticles lower triglyceride in hepatocytes through liposuction effect and nano-enzyme effect.
Adropin reduces blood glucose levels in mice by limiting hepatic glucose production.
CD36 plays a negative role in the regulation of lipophagy in hepatocytes through an AMPK-dependent pathway.
Inhibition of soluble epoxide hydrolase ameliorates hyperhomocysteinemia-induced hepatic steatosis by enhancing β-oxidation of fatty acid in mice.
A novel approach to target hypoxic cancer cells via combining β-oxidation inhibitor etomoxir with radiation.
GLP-1 receptor agonist ameliorates obesity-induced chronic kidney injury via restoring renal metabolism homeostasis.
Combinatorial treatment of Rhizoma Paridis saponins and sorafenib overcomes the intolerance of sorafenib.
YAP1 enhances NF-κB-dependent and independent effects on clock-mediated unfolded protein responses and autophagy in sarcoma.
Rosiglitazone ameliorates palmitic acid-induced cytotoxicity in TM4 Sertoli cells.
The protein acetylase GCN5L1 modulates hepatic fatty acid oxidation activity via acetylation of the mitochondrial β-oxidation enzyme HADHA.
IL-25 stimulates M2 macrophage polarization and thereby promotes mitochondrial respiratory capacity and lipolysis in adipose tissues against obesity.
Protective effects of dioscin against fructose-induced renal damage via adjusting Sirt3-mediated oxidative stress, fibrosis, lipid metabolism and inflammation.
Fibroblast growth factor 21 increases hepatic oxidative capacity but not physical activity or energy expenditure in hepatic peroxisome proliferator-activated receptor γ coactivator-1α-deficient mice.
Scutellaria baicalensis regulates FFA metabolism to ameliorate NAFLD through the AMPK-mediated SREBP signaling pathway.
Disrupting SOD1 activity inhibits cell growth and enhances lipid accumulation in nasopharyngeal carcinoma.
Chronic low-dose exposure of nonylphenol alters energy homeostasis in the reproductive system of female rats.
N-3 polyunsaturated fatty acids ameliorate hepatic steatosis via the PPAR-α/CPT-1α pathway in a mouse model of parenteral nutrition.
Polyacetylene glycoside attenuates ischemic kidney injury by co-inhibiting inflammation, mitochondria dysfunction and lipotoxicity.
Zoledronate dysregulates fatty acid metabolism in renal tubular epithelial cells to induce nephrotoxicity.
PIK3R3 regulates PPARα expression to stimulate fatty acid β-oxidation and decrease hepatosteatosis.
Adipose-specific lipin1 overexpression in mice protects against alcohol-induced liver injury.
The role of autophagy during murine primordial follicle assembly.
Quiescent Endothelial Cells Upregulate Fatty Acid β-Oxidation for Vasculoprotection via Redox Homeostasis.
Paeoniflorin Ameliorates Fructose-Induced Insulin Resistance and Hepatic Steatosis by Activating LKB1/AMPK and AKT Pathways.
Mitochondria-targeted ubiquinone (MitoQ) enhances acetaldehyde clearance by reversing alcohol-induced posttranslational modification of aldehyde dehydrogenase 2: A molecular mechanism of protection against alcoholic liver disease.
Fish oil feeding reverses hepatomegaly and disrupted hepatic function due to the lack of FXR signaling.
A signature of enhanced lipid metabolism, lipid peroxidation and aldehyde stress in therapy-induced senescence.
Kupffer cells activation promoted binge drinking-induced fatty liver by activating lipolysis in white adipose tissues.
Attenuation of hepatic steatosis by purple sweet potato colour is associated with blocking Src/ERK/C/EBPβ signalling in high-fat-diet-treated mice.
Mitochondrial Priming by CD28.
p38α MAPK antagonizing JNK to control the hepatic fat accumulation in pediatric patients onset intestinal failure.
Targeted Metabolomics Reveals Abnormal Hepatic Energy Metabolism by Depletion of β-Carotene Oxygenase 2 in Mice.
Xyloketal B Attenuates Fatty Acid-Induced Lipid Accumulation via the SREBP-1c Pathway in NAFLD Models.
Aerobic capacity mediates susceptibility for the transition from steatosis to steatohepatitis.
Pharmacological inhibition of NOX4 ameliorates alcohol-induced liver injury in mice through improving oxidative stress and mitochondrial function.
Calycosin attenuates triglyceride accumulation and hepatic fibrosis in murine model of non-alcoholic steatohepatitis via activating farnesoid X receptor.
RNA Binding Protein Ybx2 Regulates RNA Stability During Cold-Induced Brown Fat Activation.
Lipid catabolism inhibition sensitizes prostate cancer cells to antiandrogen blockade.
Hepatic overproduction of 13-HODE due to ALOX15 upregulation contributes to alcohol-induced liver injury in mice.
Medium-chain fatty acid reduces lipid accumulation by regulating expression of lipid-sensing genes in human liver cells with steatosis.
Sodium sulfite promotes the assembly and secretion of very low-density lipoprotein in HL-7702 hepatocytes.
Dysregulation of hepatic cAMP levels via altered Pde4b expression plays a critical role in alcohol-induced steatosis.
Molecular regulation of apoptotic machinery and lipid metabolism by mTORC1/mTORC2 dual inhibitors in preclinical models of HER2+/PIK3CAmut breast cancer.
High-fat diet enhances stemness and tumorigenicity of intestinal progenitors.
TXNIP regulates myocardial fatty acid oxidation via miR-33a signaling.
Effects of a block in cysteine catabolism on energy balance and fat metabolism in mice.
HDAC4 mediates IFN-γ induced disruption of energy expenditure-related gene expression by repressing SIRT1 transcription in skeletal muscle cells.
Foxp3 and Toll-like receptor signaling balance T(reg) cell anabolic metabolism for suppression.
A Novel Function of Hepatic FOG2 in Insulin Sensitivity and Lipid Metabolism Through PPARα.
Acetyl-coenzyme A carboxylase alpha promotion of glucose-mediated fatty acid synthesis enhances survival of hepatocellular carcinoma in mice and patients.
Diet rich in Docosahexaenoic Acid/Eicosapentaenoic Acid robustly ameliorates hepatic steatosis and insulin resistance in seipin deficient lipodystrophy mice.
Efficacy of Berberine in Patients with Non-Alcoholic Fatty Liver Disease.
AMP-Activated Protein Kinase Interacts with the Peroxisome Proliferator-Activated Receptor Delta to Induce Genes Affecting Fatty Acid Oxidation in Human Macrophages.
Niche-dependent regulations of metabolic balance in high-fat diet-induced diabetic mice by mesenchymal stromal cells.
Proteomics-based metabolic modeling reveals that fatty acid oxidation (FAO) controls endothelial cell (EC) permeability.
Astrocyte Elevated Gene-1 (AEG-1) Regulates Lipid Homeostasis.
High metastaticgastric and breast cancer cells consume oleic acid in an AMPK dependent manner.
Fatty acid oxidation is dispensable for human macrophage IL-4-induced polarization.
HIF-1-mediated suppression of acyl-CoA dehydrogenases and fatty acid oxidation is critical for cancer progression.
A compound heterozygous mutation in GPD1 causes hepatomegaly, steatohepatitis, and hypertriglyceridemia.
Inhibition of macrophage fatty acid β-oxidation exacerbates palmitate-induced inflammatory and endoplasmic reticulum stress responses.
Identification of 5' AMP-activated kinase as a target of reactive aldehydes during chronic ingestion of high concentrations of ethanol.
SIRT1 activation by methylene blue, a repurposed drug, leads to AMPK-mediated inhibition of steatosis and steatohepatitis.
KLF15 is a molecular link between endoplasmic reticulum stress and insulin resistance.
Chinese medicine formula lingguizhugan decoction improves Beta-oxidation and metabolism of Fatty Acid in high-fat-diet-induced rat model of Fatty liver disease.
Binge ethanol-induced HDAC3 down-regulates Cpt1α expression leading to hepatic steatosis and injury.
Anti-miR-33 therapy does not alter the progression of atherosclerosis in low-density lipoprotein receptor-deficient mice.
An iTRAQ proteomic study reveals an association between diet-induced enhanced fatty acid metabolism and the development of glucose intolerance in prediabetic mice.
Role of sirtuin 1 in the regulation of hepatic gene expression by thyroid hormone.
SILAC-based proteomics of human primary endothelial cell morphogenesis unveils tumor angiogenic markers.
An active metabolite of oltipraz (M2) increases mitochondrial fuel oxidation and inhibits lipogenesis in the liver by dually activating AMPK.
Binge alcohol-induced microvesicular liver steatosis and injury are associated with down-regulation of hepatic Hdac 1, 7, 9, 10, 11 and up-regulation of Hdac 3.
Genomic alterations with impact on survival in esophageal squamous cell carcinoma identified by array comparative genomic hybridization.
Establishing a relationship between prolactin and altered fatty acid β-oxidation via carnitine palmitoyl transferase 1 in breast cancer cells.
Expression of miR-33 from an SREBP2 intron inhibits cholesterol export and fatty acid oxidation.
Pan J, Wang Y, Feng Y, Wang J, Huang Q, Yan L, Zhou X, Sun H, Wang H, Wei Q
Bioactive materials 2026 Sep;63:718-731
Bioactive materials 2026 Sep;63:718-731
Interleukin-10 Derived Apoptotic Vesicles Enhance Scarless Skin Healing by Modulating Fibroblast Metabolism and Fibrosis Pathways.
Zou Y, Zhang J, Mao W, Jiang S, Xu C, Meng J, Dong H, Mou Y
Cell proliferation 2026 May;59(5):e70135
Cell proliferation 2026 May;59(5):e70135
Acox1 induces lipid peroxidation and metabolic shifting to promote PASMCs proliferation in hypoxia-induced pulmonary hypertension.
Liang Q, Wang Y, Zhang X, Guo D, Qu G, Sun N, Xu J, Niu X, Liu Y, Geng J, Luo H, Wang C, Xin M, Wang X, Li Y, Jin F, Hu L
Free radical biology & medicine 2026 May;248:469-484
Free radical biology & medicine 2026 May;248:469-484
Xiayuxue decoction alleviates MASH by regulating gut microbiota, bile acid metabolism, and m(6)A modification.
Shi J, Zhao C, Zhang D, Zhang L, Feng Q, Qi S, He X, Liu P, Mu Y, Chen G, Ma W, Peng D, Li R, Wang Y, Cheng Y, Liu W
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 May;154:158023
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 May;154:158023
Integrated Proteomics and Metabolomics Reveal the Direct Hepatic Protection of Propionate Against Alcoholic Liver Disease via the RGN-PPARα Pathway.
Wang H, Liu H, Wang M, Chi T, Liu F, Qu X, Mu Y, Xu Q, Wang Q
Nutrients 2026 Mar 9;18(5)
Nutrients 2026 Mar 9;18(5)
Asymmetric dimethylguanidino valeric acid as an independently associated risk factor for early hypertriglyceridemia and dyslipidemia.
Han Y, Xiong Q, Wang J, Wang A, Chen Q, Liu Y, Cheng K
Metabolomics : Official journal of the Metabolomic Society 2026 Mar 7;22(2)
Metabolomics : Official journal of the Metabolomic Society 2026 Mar 7;22(2)
Fermented Black Soybean and Dehulled Adlay Improve Metabolic Syndrome via AMPK-SIRT1 Activation and Gut Microbiota Modulation.
Kuo YR, Zheng YW, Ho PY, Lo YC, Tsai PJ, Pan MH
Journal of agricultural and food chemistry 2026 Mar 4;74(8):6864-6877
Journal of agricultural and food chemistry 2026 Mar 4;74(8):6864-6877
Dendrobium officinale polysaccharide ameliorate hyperlipidemia through LKB1/AMPK and CD36/PGC-1α/UCP1 activation and gut microbiota modulation.
Gong Y, Fang H, Wu L, Zhang J, Wen Y, Rao Y, Zhao Y
Naunyn-Schmiedeberg's archives of pharmacology 2026 Mar 4;
Naunyn-Schmiedeberg's archives of pharmacology 2026 Mar 4;
cGAS-STING signaling pathway promotes ischemic kidney injury by regulating HK3-mediated lipid accumulation.
Wang D, Zhou Z, Zhao Z, Liu M, Li Y, Mu L, Zhou H, Li X, Zhang F, Tian S, Zhou X, Shi Y
Free radical biology & medicine 2026 Jun;249:246-259
Free radical biology & medicine 2026 Jun;249:246-259
Atractylodin ameliorates obesity-associated hepatic steatosis by regulating the PLIN2-ATGL/CPT1A axis-mediated lipid droplet-mitochondria interactions.
Chen J, Wei Z, Song Z, Meng S, An J, Zhang Z, Biao Y, Zhang M, Zhang Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Jun;155:158134
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Jun;155:158134
Caveolin-1 deficiency exacerbates liver fibrosis by driving lipid metabolic reprogramming in hepatic stellate cells via DRP1-mediated mitochondrial fission.
Wang Y, Wang X, Lin J, Zhang W, Sun Y, Geng Q, Chen S, Zhang C, Jin L, Hu C
Free radical biology & medicine 2026 Jul;250:203-215
Free radical biology & medicine 2026 Jul;250:203-215
Monascus pilosus SWM-008-Fermented Red Mold Rice and Its Monascinol Ameliorate Non-Alcoholic Fatty Liver Disease via Activation of the AMPK-ATGL Pathway and Enrichment of Butyrate-Producing Bacteria.
Hsieh CP, Hsu YW, Pan TM, Lee CL
Molecular nutrition & food research 2026 Jan;70(1):e70342
Molecular nutrition & food research 2026 Jan;70(1):e70342
PGC-1α Transcriptionally Regulated by ChREBP Mitigates Neuropathic Pain Through Promoting Microglial Fatty Acid Oxidation and Anti-Inflammatory Response.
Hu Z, Pang J, Liu X, Zhao Y, Lu Y, Chen H, Zeng H, Yu Y, Zhao Y, Gao L, Zhang X, Jin J, Wang K, Shi Y, Zhan H, Wu W
CNS neuroscience & therapeutics 2026 Jan;32(1):e70744
CNS neuroscience & therapeutics 2026 Jan;32(1):e70744
Thallium exposure disturbs gut microbiota composition, metabolic function, and host gut energy metabolism in aged mice.
Yao H, Su Q, Dai Q, Li L, Li D
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2026 Jan;207:115793
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2026 Jan;207:115793
Functional analysis and regulation mechanism of FGF19 on lipid metabolism in liver of large yellow croaker (Larimichthys crocea).
Du J, Sun Y, Zhang J, Xu W, Mai K, Ai Q
Biochimica et biophysica acta. Molecular and cell biology of lipids 2026 Jan;1871(1):159700
Biochimica et biophysica acta. Molecular and cell biology of lipids 2026 Jan;1871(1):159700
Baicalin attenuates pulmonary hypertension by targeting AMPK/CPT1A-mediated fatty acid metabolism.
Chen M, He Y, Zhu X, Luo Y, Yan G, Li Y, Huang S, Shui X, Lei W
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Jan;150:157703
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Jan;150:157703
Anti-Diabetic Effects of Ayanin, a Flavonoid Compound, in STZ/HFD-Induced Diabetic Mice by Upregulating GLUT4 and Suppressing Macrophage-Driven Inflammation in Adipose Tissues.
Lv Y, Wu C, Yang W, Wang C, Huang J, Wang J, Xia X, Wu D, Yang K, Guo Z, Liao S
Food science & nutrition 2026 Jan;14(1):e71429
Food science & nutrition 2026 Jan;14(1):e71429
Lingguizhugan decoction improves cognitive impairment in APP/PS1 mice by promoting meningeal lymphatic drainage based on fatty acid degradation pathway.
Shen Z, Wu M, Sun S, Ling Y, Chen X, Zhang J, Zhou X, Zhou C
Journal of ethnopharmacology 2026 Jan 30;355(Pt B):120748
Journal of ethnopharmacology 2026 Jan 30;355(Pt B):120748
Multi-omics analysis reveals that FABP2 suppresses colorectal cancer progression by regulating sphingomyelin metabolism via the PPAR signaling pathway.
Wang P, Du K, Tian Y, Qiao X, Yang Y, Zheng G, He W, Kang J, Zhang J, Zhang Z, Feng F, Zheng J
Cancer cell international 2026 Jan 27;26(1):98
Cancer cell international 2026 Jan 27;26(1):98
ISG15 orchestrates dynamic crosstalk between mitochondrial fat oxidation and type 1 interferon in myeloid cells.
Gupta AK, Wu J, Das P, Sharma R, Das S, Han K, Klein RJ, Huffstutler RD, Combs C, Leonard WJ, Kemper C, West EE, Sack MN
bioRxiv : the preprint server for biology 2026 Jan 21;
bioRxiv : the preprint server for biology 2026 Jan 21;
Integrated microbiota and metabolomic analysis demonstrates the growth-promoting effects of Lactobacillus plantarum in Nile tilapia (Oreochromis nilotica).
Li L, Wang Y, Li Y, Wang T, Wang Z, Zhou N, Qiao F, Du ZY, Zhang ML
Animal microbiome 2026 Jan 14;8(1):14
Animal microbiome 2026 Jan 14;8(1):14
Effects of Piperine on Obese and Lean Nonalcoholic Fatty Liver Disease in Mice.
Fan JB, Qin LQ, Ding L, Zhang L, Shao MM, Tong X, Xu JY
Journal of gastroenterology and hepatology 2026 Feb;41(2):753-762
Journal of gastroenterology and hepatology 2026 Feb;41(2):753-762
Cardiac PTN-SIRT1 axis alleviates oxidative stress and promotes mitochondrial energy reprogramming to mitigate doxorubicin-induced cardiotoxicity through AMPK/PGC1α signaling.
Sun Y, Wei T, Xu H, Li H, Zhou C, Liu X, Li Y, Huang S, Zhang Q, Duan X
Acta biochimica et biophysica Sinica 2026 Feb 5;58(2):421-436
Acta biochimica et biophysica Sinica 2026 Feb 5;58(2):421-436
METTL5 promotes fatty acid metabolism by modulating peroxisome to induce hepatocellular carcinoma recurrence after thermal ablation.
Xie Z, Wang L, Wu Y, Zhang Y, Wang S, Zeng X, Liang R, Long J, Guo J, Peng S, Kuang M, Lin S, Dai Z, Chen S
Molecular therapy : the journal of the American Society of Gene Therapy 2026 Feb 4;34(2):1215-1233
Molecular therapy : the journal of the American Society of Gene Therapy 2026 Feb 4;34(2):1215-1233
Human FGF1(ΔHBS) Gene Therapy as Treatment for Metabolic Dysfunction-Associated Steatohepatitis in ApoE-KO Mice.
Li Y, Hui X, Gu C, Lin Q, Abdelbaset-Ismail A, Xu Z, Yadav S, Huang H, Xu J, Watson SE, Wintergerst KA, Cai L, Deng Z, Tan Y
Cells 2026 Feb 24;15(5)
Cells 2026 Feb 24;15(5)
Diosgenin alleviates hepatic fibrosis via PI3K/Akt/mTOR mediated fatty acid metabolic reprogramming and NF-κB activation.
Shi Y, Zhang Y, Liu D, Xiang S, Liang S, Lin W, Li S, Zhai X, Cheng B
Journal of ethnopharmacology 2026 Aug 10;367:121747
Journal of ethnopharmacology 2026 Aug 10;367:121747
Fatty acid scavenging enables cancer escape from KRAS inhibition.
Yuan Z, Lin B, Wang C, Miao Y, Zhang D, Meng Z, Wang G, Lowy AM, Karin M, Yang F, Sun B, Su H
bioRxiv : the preprint server for biology 2026 Apr 3;
bioRxiv : the preprint server for biology 2026 Apr 3;
Dapagliflozin induces renal lipidomic remodeling and systemic metabolic improvement.
Li A, Ye Y, Tang J, Hu J, Shi M, Wu Y, Ji C, Zhang H
Biology direct 2026 Apr 17;21(1)
Biology direct 2026 Apr 17;21(1)
Astragaloside IV delays vascular aging by enhancing mitochondrial fatty acid β-oxidation via the MLXIPL-PPARα/PGC-1α axis.
Chen X, Chen X, Xiao N, Yang Y, Li C, Pan Y, Huang H, Duan X, Deng Y, Chen C, Zeng S, Yang S, Huang Y, Huang D, Yang Y, Shu Z, Zhang L
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Apr 15;156:158183
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Apr 15;156:158183
Network toxicology and machine learning revealed the association between non-alcoholic fatty liver disease induced by polystyrene nanoplastics.
Zhang Y, Shi Y, Yang H, Li H, Li C, Liu M, Zhong Y, Huang C, Zhu L, Xu Y, Pan W
Ecotoxicology and environmental safety 2026 Apr 1;314:120058
Ecotoxicology and environmental safety 2026 Apr 1;314:120058
Palmitoyl-carnitine Regulates Lung Development by Promoting Pulmonary Mesenchyme Proliferation.
Liu X, Lam SM, Zheng Y, Mo L, Li M, Sun T, Long X, Peng S, Zhang X, Mei M, Shui G, Bao S
Research (Washington, D.C.) 2025;8:0620
Research (Washington, D.C.) 2025;8:0620
Aerobic exercise improved liver steatosis by modulating miR-34a-mediated PPARα/SIRT1-AMPK signaling pathway.
Wu B, Zhang Z, Xu C, Zhao J
PloS one 2025;20(11):e0333872
PloS one 2025;20(11):e0333872
Hyodeoxycholic Acid Ameliorates Metabolic Syndrome Through Pathways of Primary Bile Acid Synthesis and Fatty Acid Degradation: Insights From a Rat Model.
Chen M, Huang K, Luo W, Zhang F, Gan H, Yang Z
Drug design, development and therapy 2025;19:3611-3630
Drug design, development and therapy 2025;19:3611-3630
Improved myocardial mitochondrial energy metabolism in rats with chronic heart failure by modifying fatty acid oxidation using an extract of sand-fired aconite (Jianchang gang processing).
Zhang H, Huang Y, Yang S, Gong F, Gu Y, Xie Q, Ye Y, Lu X, Zhong L
Frontiers in pharmacology 2025;16:1600410
Frontiers in pharmacology 2025;16:1600410
Mechanistic insights into the PAI-1 inhibitor PAItrap3: enhancing lipid metabolism in adipose tissue of diabetic db/db mice.
Wang L, Zhang Z, Lin M, Qi L, Liu L, Chen Z, Tang S, Wang L
Frontiers in pharmacology 2025;16:1596655
Frontiers in pharmacology 2025;16:1596655
FOXK2 regulates fatty acid metabolism and promotes cervical cancer progression by activating the mTOR/DRP1 signaling axis.
Liao D, Zeng S, Li C, Yao Y, Guo M, Cui Y, Huang H
Frontiers in cell and developmental biology 2025;13:1615454
Frontiers in cell and developmental biology 2025;13:1615454
Reduction in within-litter variation of piglet birth weight through dietary supplementation of 3-hydroxyisobutyric acid in sows.
Che L, Niu L, Liu L, Li M, Huo W, Deng H, Chen W, Pang L, Xu M
Frontiers in veterinary science 2025;12:1646332
Frontiers in veterinary science 2025;12:1646332
Chromatin remodeler BRD9 represses transcription of PPARα target genes, including CPT1A to suppress lipid metabolism.
Yokoseki I, Nakano M, Kurosawa K, Higuchi Y, Uehara S, Yoneda N, Suemizu H, Fukami T, Nakajima M
Journal of lipid research 2025 Sep;66(9):100874
Journal of lipid research 2025 Sep;66(9):100874
Protective potential of bempedoic acid as an AMPK activator in tamoxifen-induced steatohepatitis in rats.
Mosaad M, El-Sayed EK, El Morsy EM
Naunyn-Schmiedeberg's archives of pharmacology 2025 Sep;398(9):12661-12672
Naunyn-Schmiedeberg's archives of pharmacology 2025 Sep;398(9):12661-12672
Selective and iron-independent ferroptosis in cancer cells induced by manipulation of mitochondrial fatty acid oxidation.
Gao Y, Song Z, Gan W, Zou X, Bai Y, Zhao X, Chen D, Qiao M
Biomaterials 2025 Sep;320:123259
Biomaterials 2025 Sep;320:123259
Cigarette smoke-induced PPAR signaling dysregulation accelerates Alzheimer's disease pathogenesis and cognitive decline in 5xFAD mice.
Xie Y, Wang H, Zhang Y, Lin B, Chen Y, Li K, Tang H, Sun Q
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2025 Sep;203:115596
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2025 Sep;203:115596
Mechanisms of metabolic-associated fatty liver disease induced by 48-week PCB138 exposure and theabrownin intervention.
Han J, Liu C, Chen Z, Ruan F, Xue F, Ye L, Yu Y, Zuo Z, He C
Environment international 2025 Sep;203:109780
Environment international 2025 Sep;203:109780
Choline reduces inflammatory response and lipid accumulation in calf hepatocytes induced by NEFA via inhibiting ROS/ NF-κB/NLRP3 inflammasome axis.
Zhang R, Du X, Hu H, Chen J, Yu J, Wang L, Yao J, Liu S, Wang J, Cao Y
Molecular immunology 2025 Sep;185:116-126
Molecular immunology 2025 Sep;185:116-126
Mitochondrial fatty acid oxidation dysfunction impairs autophagic flux through ATP deficiency-caused lysosomal pH abnormity.
Zhang YY, Lv ZD, Wang M, Wang JX, Limbu SM, Qiao F, Chen LQ, Zhang ML, Luo Y, Du ZY
The Journal of nutritional biochemistry 2025 Sep;143:109943
The Journal of nutritional biochemistry 2025 Sep;143:109943
Betaine decreases hepatic lipid deposition through DNA 5 mC and RNA m(6)A methylation-mediated regulation of fatty acid metabolic genes expression in laying hens.
Yang Y, Jin X, Lu D, Wu Y, Meng F, Zhang M, Wang J, Cui X, Li T, Wang S, Luo X, Hu Y
Poultry science 2025 Sep;104(9):105496
Poultry science 2025 Sep;104(9):105496
Mitochondrial CCN1 drives ferroptosis via fatty acid β-oxidation.
Guo W, Zhang C, Zhou Q, Chen T, Xu X, Zhang J, Yu X, Wu H, Zhang X, Ma L, Qian K, Klionsky DJ, Kang R, Kroemer G, Yu Y, Tang D, Wang J
Developmental cell 2025 Sep 8;60(17):2294-2312.e11
Developmental cell 2025 Sep 8;60(17):2294-2312.e11
Chronic Waterborne Exposure to Polystyrene Microplastics Induces Kupffer Cell Polarization Imbalance and Hepatic Lipid Accumulation.
Li T, Yao Z, Huang Y, Li R, Zhang L, Chen R, Gu W
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Sep 15;39(17):e70980
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Sep 15;39(17):e70980
Novel Pretreatment Autoantibodies Correlate with Enfortumab Vedotin-Related Dermatologic Events in Patients with Advanced Urothelial Cancer.
Vlachou E, Johnson BA 3rd, McConkey DJ, Hahn NM, Jing Y, Russell S, Stairiker D, Rosen A, Casciola-Rosen LA, Hoffman-Censits J
Cancer research communications 2025 Sep 1;5(9):1674-1680
Cancer research communications 2025 Sep 1;5(9):1674-1680
A galacturonan from sea buckthorn (Hippophae rhamnoides L.) berry modulates dyslipidemia by promoting hepatic lipolysis and mitochondrial oxidation.
Sun Y, Ni W, Wang D, Ren J, Zhao D, Yu S, Liu S, Zhang S, Wang S, Wang W, Liu M
Carbohydrate polymers 2025 Sep 1;363:123708
Carbohydrate polymers 2025 Sep 1;363:123708
PPARα activation attenuated heat-induced myocardial injury in mice.
Hu Z, Zhao L, Ma X, Li R, Qin L, Zhang L, Hou T, Zhang G, Liu C
Ecotoxicology and environmental safety 2025 Sep 1;302:118520
Ecotoxicology and environmental safety 2025 Sep 1;302:118520
Effect of rumen-protected guanidinoacetic acid provision as a dietary supplement on the growth, slaughter performance, and meat quality in simmental bulls.
Zhang J, Xue C, Lang J, Pei C, Liu Q
Meat science 2025 Oct;228:109889
Meat science 2025 Oct;228:109889
Glia maturation factor-β deficiency improves insulin resistance by promoting CARM1-mediated lipid turnover.
Xu J, Zhu L, Li J, Xu J, Cui T, Jia S, Zhu T, Shi S, Gao F, Jin C, Tian H, Wang J, Ou Q, Xu JY, Bi YL, Xu GT, Zhang X, Lu L
Pharmacological research 2025 Oct;220:107937
Pharmacological research 2025 Oct;220:107937
TRIM34 inhibits triple-negative breast cancer progression by attenuating fatty acid synthesis via facilitating FASN ubiquitination.
Li Y, Shan J, Liu S, Shen Y, Niu L, Mao Q, Chen X
Biochimica et biophysica acta. Molecular basis of disease 2025 Oct;1871(7):167958
Biochimica et biophysica acta. Molecular basis of disease 2025 Oct;1871(7):167958
ILF3 mediates lipid metabolism to promote pancreatic cancer development by regulating CPT1A-activated PPARa signaling pathway.
Zhan T, Chen M, Zhu Q, Liu M, Tan J, Chen X, Liu J, Han Z, Zou Y, Tian X, Huang X
Biochimica et biophysica acta. Molecular basis of disease 2025 Oct;1871(7):167919
Biochimica et biophysica acta. Molecular basis of disease 2025 Oct;1871(7):167919
Network pharmacology and transcriptomics reveal complanatoside A regulates lipid metabolism in hyperlipidemia and nonalcoholic fatty liver disease via the AMPK pathway.
Jiang S, Liang Z, Hua J, Li Y, Fan X, Qiao Z, Wang Z, Shen Y, Fan L, Wang J
The Journal of nutritional biochemistry 2025 Oct;144:109960
The Journal of nutritional biochemistry 2025 Oct;144:109960
TRIM59 deficiency aggravates HFD-induced obesity in mice associated with increased adipose tissue inflammation, lipid accumulation, and apoptosis.
Chen Y, Han X, Liu T, Ni Y, Deng X, Wei W, Jiang M
Cellular signalling 2025 Oct;134:111954
Cellular signalling 2025 Oct;134:111954
Fenofibrate alleviates sepsis-associated acute kidney injury by enhancing renal fatty acid oxidation.
Zeng S, Wang J, Guan C, Yao Z, Zhang Y, Li Y, Zheng J, Wang H
BMC pharmacology & toxicology 2025 Oct 7;26(1):160
BMC pharmacology & toxicology 2025 Oct 7;26(1):160
MTCH2 modulates CPT1 activity to regulate lipid metabolism of adipocytes.
Wu C, Wang T, Ghosh A, Long F, Sharma AK, Dahlby T, Noé F, Severi I, Colleluori G, Cinti S, Giordano A, Ding L, Khandelwal R, Kostidis S, Giera M, Balazova L, Gardeux V, Abu-Nawwas L, Deplancke B, Chourasia S, Kleiner S, Hamilton BS, Alcántara JMA, Ruiz JR, Blüher M, Pekcec A, Balaz M, Gross A, Neubauer H, Wolfrum C
Nature communications 2025 Oct 3;16(1):8831
Nature communications 2025 Oct 3;16(1):8831
CPT1A inhibition alleviates plasmacytoid dendritic cell-mediated immune suppression in colon cancer through fatty acid oxidation modulation.
Wu J, Zhu S, Zang G, Wang H, Yang N, Qiao Y, Wei Q, Wang L, Ren Z, Liu YJ, Chen J
Journal for immunotherapy of cancer 2025 Oct 23;13(10)
Journal for immunotherapy of cancer 2025 Oct 23;13(10)
Salidroside improves bovine embryo quality by mitigating oxidative stress and regulating mitochondrial lipid metabolism.
Liu LY, Yu XF, Chi ZC, Shi SM, Lan T, Leng JH, Li JH, He YY, Qu LY, Jia GL, Kong I, Zhang MJ, Jin YX
Theriogenology 2025 Nov;247:117570
Theriogenology 2025 Nov;247:117570
Maternal exposure to high level of ursodeoxycholic acid during pregnancy promotes hepatic lipid deposition in the offspring by reducing the methylation level of Fasn gene.
Hu D, Wu X, Hou M, Song P, Chen Q, Ni Y
Biochemical pharmacology 2025 Nov;241:117156
Biochemical pharmacology 2025 Nov;241:117156
Subacute exposure to thallium disrupts renal energy metabolism by impairing the function of subcellular organelles in aged mice of both sexes.
Yao H, Li L, Dai Q, Li D
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2025 Nov;205:115700
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2025 Nov;205:115700
Syndecan-1 regulates lipid metabolism and mitigates fibrosis during the transition from acute kidney injury to chronic kidney disease.
Shen D, Lin L, Su Y, Huang Y, Wang Y, Xu J, Jiang W, Zhang Z, Ding X, Xu X
Metabolism: clinical and experimental 2025 Nov;172:156374
Metabolism: clinical and experimental 2025 Nov;172:156374
The modulation of mTOR signaling on dietary carbohydrate utilization in largemouth bass (Micropterus salmoides).
Lv M, Yang K, Wang X, Liu C, Zhou H, Mai K, He G
The Journal of nutritional biochemistry 2025 Nov;145:110008
The Journal of nutritional biochemistry 2025 Nov;145:110008
Inflammation and Mitochondrial Dysfunction in Cirrhotic Cardiomyopathy: Therapeutic Implications.
Ding Y, Huang C, Yang G, Liu E, Wang Z, Su Y, Ge C
Journal of clinical and translational hepatology 2025 Nov 28;13(11):905-917
Journal of clinical and translational hepatology 2025 Nov 28;13(11):905-917
NAT10-mediated lipid metabolic reprogramming drives EGFR-TKI resistance in non-small cell lung cancer via ac4C-dependent mRNA stabilization.
Fang S, Zhu Y, Chen W, Mao W, Fang Y, Chen Z, Hong Z, Zhao X, Su W, Pan Y, Yao G, Wang J, Zhou C
Experimental hematology & oncology 2025 Nov 27;14(1):134
Experimental hematology & oncology 2025 Nov 27;14(1):134
GSTK1 suppresses HCC aggravation via L-carnitine metabolism by PGAM5/DRP1 complex-mediated mitochondrial quality control.
Shi Y, Zhang J, Song B, Zhang H, He J, Ding K, Wang F, Yu W, Zhangyuan G, Jin K, Zhang W, Sun B
Journal of experimental & clinical cancer research : CR 2025 Nov 24;45(1):1
Journal of experimental & clinical cancer research : CR 2025 Nov 24;45(1):1
Roseburia hominis enriched by baicalin reverses the non-response to metformin via upregulating linolenic acid metabolism.
Miao Z, Long J, Huang B, Yan D, Wang A
iScience 2025 Nov 21;28(11):113892
iScience 2025 Nov 21;28(11):113892
Tau impedes glioma progression by enhancing fatty acid β-oxidation-induced cellular senescence.
Han WH, Zhao WJ, He JW, Zhao WP, Lu HW, Lu ZW, Qiu XS, Chang C, Zhang YY, Xie YY, Geng YY, Zhang BC, Wang ZX
Zoological research 2025 Nov 18;46(6):1304-1316
Zoological research 2025 Nov 18;46(6):1304-1316
Activation of TRPA1 prevents metabolic dysfunction-associated steatotic liver disease in diet-induced obese mice through stimulating the AMPK/CPT1A signaling pathway.
Wang D, Liu S, Wan J, Chen S, Feng K, Hou J, Yang Y, Wang P
Journal of physiology and biochemistry 2025 May;81(2):359-373
Journal of physiology and biochemistry 2025 May;81(2):359-373
Aurantio-Obtusin Regulates Gut Microbiota and Serum Metabolism to Alleviate High-Fat Diet-Induced Obesity-Associated Non-Alcoholic Fatty Liver Disease in Mice.
Li Z, Jin Y, Zhao H, Gu Y, Zhang Y, Cheng S, Zhang L, He P, Liu X, Jia Y
Phytotherapy research : PTR 2025 May;39(5):1946-1965
Phytotherapy research : PTR 2025 May;39(5):1946-1965
AMPKα alleviates the inhibitory effect of NEFA on the function of bovine follicular granulosa cells cultured in vitro.
Zhao C, Xu R, Xin S, Jiang B, Feng S, Wang X, Xia C
Animal reproduction science 2025 May;276:107831
Animal reproduction science 2025 May;276:107831
Steam explosion modified pea peptides alleviates hepatosteatosis by regulating lipid metabolism pathways and promoting autophagy.
Zhang J, Song L, Li T, Zhu L, Wang T, Zhao P, Ma Y, Zhao J, Huang X
Food research international (Ottawa, Ont.) 2025 May;208:116182
Food research international (Ottawa, Ont.) 2025 May;208:116182
LncRNA SNHG4 Regulates Lipid Metabolism and Inflammation in Non-Alcoholic Fatty Liver Disease by Targeting miR-34b-5p/XIAP Axis.
Ding Y, Zheng S, Fu XN, Ma C, Juan Y
The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology 2025 May 5;36(10):629-640
The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology 2025 May 5;36(10):629-640
METTL3-Driven m6A Modification of Cpt1a Gene in High Fat Diet Related Liver Cancer Tumor Macrophages Facilitates Type II Macrophage Differentiation.
Zhu L, Li X, Wang W
Frontiers in bioscience (Landmark edition) 2025 May 26;30(5):36971
Frontiers in bioscience (Landmark edition) 2025 May 26;30(5):36971
CPT1A/HIF-1α positive feedback loop induced fatty acid oxidation metabolic pathway contributes to the L-ascorbic acid-driven angiogenesis in breast cancer.
Ma X, Zhang B, Yin X, Yang S, Lin Z, Yang Y, Zhou X
Breast cancer research : BCR 2025 May 12;27(1):74
Breast cancer research : BCR 2025 May 12;27(1):74
Dietary coconut oil lowered circulating fetuin-A levels and hepatic expression of fetuin-A in KK/TaJcl mice.
Iizuka Y, Kitagawa C, Tamura T, Ueshiba H, Hirako S, Osaka T, Kim H, Yanagisawa N
Journal of clinical biochemistry and nutrition 2025 Mar;76(2):131-138
Journal of clinical biochemistry and nutrition 2025 Mar;76(2):131-138
Alterations in PD-L1 succinylation shape anti-tumor immune responses in melanoma.
Liang L, Kuang X, He Y, Zhu L, Lau P, Li X, Luo D, Gong L, Zhou W, Zhang F, Liang X, Li Z, Hu B, Liu D, Ding T, Li H, Zhao S, Su J, Hung MC, Liu J, Liu H, Chen X
Nature genetics 2025 Mar;57(3):680-693
Nature genetics 2025 Mar;57(3):680-693
LncRNA Gm35585 transcriptionally activates the peroxidase EHHADH against diet-induced fatty liver.
Jin M, Lu Q, Xia N, Fan X, Zhang Z, Huang X, Sun L, Zhang L, Jiang Z, Yu Q
Experimental & molecular medicine 2025 Mar;57(3):652-666
Experimental & molecular medicine 2025 Mar;57(3):652-666
The mediator subunit complex protein MED15 promotes lipid deposition and cancer progression during hypoxia.
Zhang B, Zhu Y, Tang Y, Liu L, Liu Y, Li Y, Yu W, Lu L
The Journal of biological chemistry 2025 Mar;301(3):108296
The Journal of biological chemistry 2025 Mar;301(3):108296
Structural characterization of polysaccharides from Polygonatum Sibiricum and effect on alleviating hyperlipidemia in egg yolk emulsion-induced mice.
Zhao L, Peng Y, Huang J, Liu N, Zou X, Li J, Fan Y, Li P, Tang L, Wang J, Zeng Y, Wu Y, Zhu G
International journal of biological macromolecules 2025 Mar;296:139808
International journal of biological macromolecules 2025 Mar;296:139808
Meteorin-like protein alleviates intervertebral disc degeneration by suppressing lipid accumulation in nucleus pulposus cells via PPARα-CPT1A activation.
Huang Z, Shi M, Zhang C, Deng Z, Qin T, Wu J, Zhang X, Han W, Li S, Gao B, Xiao Y, Huang D, Ye W
Biochimica et biophysica acta. Molecular basis of disease 2025 Mar;1871(3):167635
Biochimica et biophysica acta. Molecular basis of disease 2025 Mar;1871(3):167635
Parabacteroides distasonis promotes liver regeneration by increasing β-hydroxybutyric acid (BHB) production and BHB-driven STAT3 signals.
Guo M, Jiang X, Ouyang H, Zhang X, Zhang S, Wang P, Bi G, Wu T, Zhou W, Liang F, Yang X, Fan S, Fang JH, Chen P, Bi H
Acta pharmaceutica Sinica. B 2025 Mar;15(3):1430-1446
Acta pharmaceutica Sinica. B 2025 Mar;15(3):1430-1446
Qige Decoction attenuated non-alcoholic fatty liver disease through regulating SIRT6-PPARα-mediated fatty acid oxidation.
Fan S, Chen W, Li Y, Guo K, Tang H, Ye J, Zhou Z, Tan M, Wei H, Huang X, Huang K, Ke X
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Mar;138:156395
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Mar;138:156395
Impact of DNAH3 deficiency on sperm energy metabolism and motility leading to asthenozoospermia†.
Li J, Liu Y, Kong P, Chang Q, Chen S, Yang W, Liu W, Teng X, Guo Y
Biology of reproduction 2025 Mar 16;112(3):501-512
Biology of reproduction 2025 Mar 16;112(3):501-512
Impaired fatty acid import or catabolism in macrophages restricts intracellular growth of Mycobacterium tuberculosis.
Simwela NV, Jaecklein E, Sassetti CM, Russell DG
eLife 2025 Mar 13;13
eLife 2025 Mar 13;13
Membrane-associated ring-CH-type finger 2 protects against metabolic dysfunction-associated fatty liver disease by targeting fatty acid synthase.
Ni D, Qi Z, Ma S, Wang Y, Liang D, Zhang X, Man Y, Chen J, Dou K, Li G
Molecular metabolism 2025 Jun;96:102137
Molecular metabolism 2025 Jun;96:102137
Phosphatidylcholine Ameliorates Palmitic Acid-Induced Lipotoxicity by Facilitating Endoplasmic Reticulum and Mitochondria Contacts in Intervertebral Disc Degeneration.
Tu S, Dong Y, Li C, Jiang M, Duan L, Zhang W, Chen X
JOR spine 2025 Jun;8(2):e70062
JOR spine 2025 Jun;8(2):e70062
Augmenting Macrophages Apoptosis Induced by Carnitine Palmitoyl Transferase 1A Inhibition via Acetyl-CoA-Associated Protein Acetylation.
Shi G, Wang R, Huang C
Immunology 2025 Jun;175(2):214-225
Immunology 2025 Jun;175(2):214-225
Linghe granules reduces hepatic lipid accumulation in Non-alcoholic fatty liver disease through regulating lipid metabolism and redox balance.
Hu Y, Li N, Zhang R, Wang J, Fang D, Zhou Q, Zhang H, Cai H, Lu Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jun;141:156654
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jun;141:156654
Asprosin-FABP5 Interaction Modulates Mitochondrial Fatty Acid Oxidation through PPARα Contributing to MASLD Development.
Yu YY, Feng M, Chen Y, Jia HL, Zhang Q, Tong M, Li YX, Zhao Y, Liu XX, Cao SF, Wang ZK, Li HW, Liu X, Zhang Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Jun;12(21):e2415846
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Jun;12(21):e2415846
Diallyl Trisulfide From Garlic Regulates RAB18 Phase Separation to Inhibit Lipophagy and Induce Cuproptosis in Hepatic Stellate Cells for Antifibrotic Effects.
Tian H, Sun S, Qiu X, Wang J, Gao Y, Chen J, Han X, Bao Z, Guo X, Sun Y, Lin Y, Hu M, Zhang F, Zhang Z, Wang F, Zheng S, Shao J
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Jun;12(21):e2415325
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Jun;12(21):e2415325
Alisol B alleviates MASLD by activating liver autophagy and fatty acid oxidation via Ces2a.
Zhang C, Chen L, Jiang Y, Qiu J, Lin Y, Ren G, Xu F, Xi J, Yu Z, Rong X, Dou X
International immunopharmacology 2025 Jun 5;157:114768
International immunopharmacology 2025 Jun 5;157:114768
Fatty Acid Oxidation Fuels Mitochondrial Respiration to Drive Epidermal Stem Cell Fate and Barrier Regeneration.
Mandinova A, Todorova K, Sol S, Boncimino F, Clocchiatti A, Takagaki K, Gantumur E, Ruseva M, Cadieux M, Liu M, Neel V, Colwell A, Lian C, Murphy G, Carmeliet P
Research square 2025 Jun 4;
Research square 2025 Jun 4;
Alectinib and SALL4-Targeted Fatty Acid Oxidation: A Strategy to Combat Oxaliplatin Resistance in Gastric Cancer.
Xiao Y, Fang K, Liao J, Zhou H, Zhu W, Liu Z, Ouyang H, Liu K
The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology 2025 Jun 23;36(12):813-821
The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology 2025 Jun 23;36(12):813-821
Alpha-synuclein mutations mislocalize cytoplasmic p300 compromising autophagy, which is rescued by ACLY inhibition.
Son SM, Siddiqi FH, Lopez A, Ansari R, Tyrkalska SD, Park SJ, Kunath T, Metzakopian E, Fleming A, Rubinsztein DC
Neuron 2025 Jun 18;113(12):1908-1924.e13
Neuron 2025 Jun 18;113(12):1908-1924.e13
Bavachin ameliorates cisplatin-induced nephrotoxicity by enhancing mitochondrial β-oxidation and lipid metabolism through MFN2.
Luo S, Yang M, Jiang N, Li C, Liu Y, Sun L
Molecular medicine (Cambridge, Mass.) 2025 Jun 11;31(1):234
Molecular medicine (Cambridge, Mass.) 2025 Jun 11;31(1):234
Targeting EPAS-1/HIF-2α Pathway to Address Endocrine Resistance in Luminal A Type Breast Cancer.
Luo E, Lee S, Agarwal NM, Choi J
Translational oncology 2025 Jul;57:102415
Translational oncology 2025 Jul;57:102415
OTUB1 enhances fatty acid oxidation in APAP-induced liver injury by mediating ACSL5 deubiquitination.
Guo S, Zhao Y, Wang Y, Lin M, Luan Q, Hu Z, Zhao X, Tian X, Wang Z, Yao J
Biochemical pharmacology 2025 Jul;237:116957
Biochemical pharmacology 2025 Jul;237:116957
Anthraquinones of Cassiae Semen alleviate lipid accumulation in obesity by regulating brown adipose tissue and liver function.
Li Y, Wu R, Li X, Li J, Zhang Y, Huang Y, Fan G, Li X
Chinese herbal medicines 2025 Jul;17(3):488-499
Chinese herbal medicines 2025 Jul;17(3):488-499
Ultrasound-Guided Functionalized Extracellular Vesicles for Visualized, Controlled, and Efficient Renal Delivery for Enhanced Kidney Repair.
Chen Y, Sheng C, Xiao T, Jiang B, Xu X, Cui S, Shen W, Zheng X, Guo X, Chen X, Zhang C, Cai G
Advanced healthcare materials 2025 Jul;14(17):e2404719
Advanced healthcare materials 2025 Jul;14(17):e2404719
Hypoxia ameliorates high-fat-diet-induced hepatic lipid accumulation by modulating the HIF2α/PP4C signaling.
Liu Z, Hou J, Tian M, Zhang Y, Huang D, Zhao N, Ma Y, Cui S
Cellular signalling 2025 Jul;131:111751
Cellular signalling 2025 Jul;131:111751
Early-life exercise extends healthspan but not lifespan in mice.
Feng M, Li M, Lou J, Wu G, Gao T, Wu F, Tan Y, Zhang N, Zhao Y, Zhao L, Li J, Shi C, Zhang X, Liu J, Gao F
Nature communications 2025 Jul 9;16(1):6328
Nature communications 2025 Jul 9;16(1):6328
PRMT1-mediated methylation of UBE2m promoting calcium oxalate crystal-induced kidney injury by inhibiting fatty acid metabolism.
Yuan T, Ye Z, Mei S, Zhang M, Wu M, Lin F, Yu W, Li W, Zhou X, Cheng F
Cell death & disease 2025 Jul 31;16(1):579
Cell death & disease 2025 Jul 31;16(1):579
IGFBP1 orchestrates metabolic reprogramming to drive clear cell renal cell carcinoma progression through NR1H4-mediated lipid homeostasis disruption.
Sun Y, Hao Y, Peng F, Ling H, Sun K, Qiu J, Yang T, Zhao L, Xia Q
Cancer cell international 2025 Jul 28;25(1):284
Cancer cell international 2025 Jul 28;25(1):284
A lipid metabolism-related gene signature for risk stratification and prognosis prediction in patients with breast cancer.
Mai W, Jiao Y, Deng T
Scientific reports 2025 Jul 26;15(1):27281
Scientific reports 2025 Jul 26;15(1):27281
Wenxia Changfu formula inhibits Lewis lung cancer metastasis by reprogramming tumor-associated macrophages through the PPAR-γ/CD36 pathway.
Yin X, Sun X, Li A, Ruan J, Niu H, Zhou Y, Chen G, Guo J, He Q, Ji X
Journal of ethnopharmacology 2025 Jul 24;351:120103
Journal of ethnopharmacology 2025 Jul 24;351:120103
High-Fat Diet-Induced Diabetic Cardiomyopathy in Female Zebrafish: Cardiac Pathology and Functional Decline Mediated by Type 2 Diabetes.
Huang S, Chen Z, Li H, Zou Y, Wang B, Zhao W, Zheng L, Zhou Z, Peng X, Tang C
Nutrients 2025 Jul 2;17(13)
Nutrients 2025 Jul 2;17(13)
Nicotinamide riboside promoted cardiac energetics and alleviated doxorubicin-induced cardiotoxicity via SIRT1/ERRα signal in human pluripotent stem cells-derived cardiomyocytes.
Wang R, Zhang H, Yi Q, Wang YP, Xu H, Tan B, Zhu J
Life sciences 2025 Jul 15;373:123685
Life sciences 2025 Jul 15;373:123685
Fatty Acid Metabolism via CPT1A Supports Poll Gland Function and Rutting Activities in Male Bactrian Camels.
Ma Q, Zhang B, Zhou B, Zhang Q, Gao Y
Biomolecules 2025 Jul 11;15(7)
Biomolecules 2025 Jul 11;15(7)
Citrus aurantium 'Changshan-huyou' physiological premature fruit drop: A promising prebiotic to tackle obesity.
Wang C, Peng M, Gao Z, Fu F, Li G, Su D, Huang L, Guo J, Shan Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jan;136:156347
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jan;136:156347
Intermittent fasting triggers interorgan communication to suppress hair follicle regeneration.
Chen H, Liu C, Cui S, Xia Y, Zhang K, Cheng H, Peng J, Yu X, Li L, Yu H, Zhang J, Zheng JS, Zhang B
Cell 2025 Jan 9;188(1):157-174.e22
Cell 2025 Jan 9;188(1):157-174.e22
Characteristics of different lipid droplet-mitochondrial contacts patterns during lipid droplet metabolism in T2DM-induced MASLD.
Xu Y, Zhang Y, Sun W, Tang Q, Feng W, Xiao H, Wang J, Yuan X, Xiang M, Gao Y, Zhang H, Lu J
Scientific reports 2025 Jan 27;15(1):3399
Scientific reports 2025 Jan 27;15(1):3399
Autophagic flux-lipid droplet biogenesis cascade sustains mitochondrial fitness in colorectal cancer cells adapted to acidosis.
Liu X, Sun X, Mu W, Li Y, Bu W, Yang T, Zhang J, Liu R, Ren J, Zhou J, Li P, Shi Y, Shao C
Cell death discovery 2025 Jan 25;11(1):21
Cell death discovery 2025 Jan 25;11(1):21
Sesamol Ameliorates Lipid Deposition by Maintaining the Integrity of the Lipid Droplet-Mitochondria Connection in Diabetic Nephropathy.
Yang M, Liu C, Jiang N, Liu Y, Luo S, Li C, Zhao H, Han Y, Li L, Xiao L, Chen W, Sun L
Journal of agricultural and food chemistry 2025 Jan 22;73(3):2124-2137
Journal of agricultural and food chemistry 2025 Jan 22;73(3):2124-2137
Moderate-intensity interval exercise exacerbates cardiac lipotoxicity in high-fat, high-calories diet-fed mice.
Geng J, Zhang X, Guo Y, Wen H, Guo D, Liang Q, Pu S, Wang Y, Liu M, Li Z, Hu W, Yang X, Chang P, Hu L, Li Y
Nature communications 2025 Jan 12;16(1):613
Nature communications 2025 Jan 12;16(1):613
Impaired fatty acid import or catabolism in macrophages restricts intracellular growth of Mycobacterium tuberculosis.
Simwela NV, Jaecklein E, Sassetti CM, Russell DG
bioRxiv : the preprint server for biology 2025 Jan 11;
bioRxiv : the preprint server for biology 2025 Jan 11;
The BET inhibitor JQ1 targets fat metabolism and counteracts obesity.
Fornelli C, Sofia Cento A, Nevi L, Mastrocola R, Ferreira Alves G, Caretti G, Collino M, Penna F
Journal of advanced research 2025 Feb;68:403-413
Journal of advanced research 2025 Feb;68:403-413
Isorhapontigenin alleviates acetaminophen-induced liver injury by promoting fatty acid oxidation.
Zha H, Lv S, Hu Y, Xie Y, Wang L, Yang C, Li G, Gong S, Ping L, Zhu D, Wang J, Weng Q, He Q, Wang J
Biochimica et biophysica acta. Molecular basis of disease 2025 Feb;1871(2):167575
Biochimica et biophysica acta. Molecular basis of disease 2025 Feb;1871(2):167575
Natural molecule isoliquiritigenin mitigates MASH and liver fibrosis in mice by promoting autophagy through the PI3K/Akt signaling pathway.
Liu R, Zhang Y, Liu M, Shang Z, Song S, Zhang Y, Zhou Y, Tu C
The Journal of nutritional biochemistry 2025 Feb;136:109808
The Journal of nutritional biochemistry 2025 Feb;136:109808
Trans 10, cis 12-conjugated linoleic acid in low concentration reduces while in high concentration enhances adipocyte metabolism but effectively improves hepatic steatosis of obese mice.
Rao Y, Yu S, Liang L, Wang Q, Lu J, Wang B, Gou K
The Journal of nutritional biochemistry 2025 Feb;136:109801
The Journal of nutritional biochemistry 2025 Feb;136:109801
Succinylation enables IDE to act as a hub of larval tissue destruction and adult tissue reconstruction during insect metamorphosis.
Li YX, Shao BY, Hou MY, Dong DJ
Science advances 2025 Feb 7;11(6):eads0643
Science advances 2025 Feb 7;11(6):eads0643
Meteorin-like alleviates hepatic steatosis by regulating hepatic triglyceride secretion and fatty acid oxidation.
Song L, Huang Y, Liu L, Chang X, Hu L, Wang G, Xu L, Zhang T, Wang Y, Xiao Y, Yang H, Ran S, Shi Q, Wang T, Shi M, Zhou Y, Guo B
Cell reports 2025 Feb 25;44(2):115246
Cell reports 2025 Feb 25;44(2):115246
Vitisin A Outperforms Cyanidin-3-O-Glucoside in Triglyceride Reduction by Modulating Hepatic Lipogenesis and Fatty Acid β-Oxidation.
Li Y, Li X, Liu J, Jayavanth P, Bai W, Jiao R
International journal of molecular sciences 2025 Feb 11;26(4)
International journal of molecular sciences 2025 Feb 11;26(4)
Ferulic acid from Angelica sinensis (Oliv.) Diels ameliorates lipid metabolism in alcoholic liver disease via AMPK/ACC and PI3K/AKT pathways.
Lu J, Wang C
Journal of ethnopharmacology 2025 Feb 10;338(Pt 3):119118
Journal of ethnopharmacology 2025 Feb 10;338(Pt 3):119118
PANAXADIOL SAPONIN ALLEVIATES LPS-INDUCED CARDIOMYOPATHY SIMILAR TO DEXAMETHASONE VIA IMPROVING MITOCHONDRIAL QUALITY CONTROL.
Yang Z, Gao Y, Li D, Zhao L, Du Y
Shock (Augusta, Ga.) 2025 Feb 1;63(2):282-291
Shock (Augusta, Ga.) 2025 Feb 1;63(2):282-291
Kaili sour soup in alleviation of hepatic steatosis in rats via lycopene route: an experimental study.
Li Y, Cong S, Chen R, Tang J, Zhai L, Liu Y
Annals of medicine 2025 Dec;57(1):2479585
Annals of medicine 2025 Dec;57(1):2479585
Alpha Ketoglutaric Acid attenuates LPS Induced Inflammatory Response by Inhibiting the PKCε/MAPK/P65 Signaling Pathway and Inhibit Oxidative Stress in Kupffer Cells.
Li Y, Kuang H, Fan G, Yang X
Inflammation 2025 Dec;48(6):4020-4030
Inflammation 2025 Dec;48(6):4020-4030
SIRT5 Facilitates Liver Steatosis Progression via Promoting SDH Desuccinylation During High-Fat Diet Feeding.
Liu Z, Hu J, Lin Y, Ge C, Shao Y, Bao M, Liu M, Jia S, Li Y, Xu X, Li R, Jiang Q, Yan F, Xiao F, Ye J
Liver international : official journal of the International Association for the Study of the Liver 2025 Dec;45(12):e70433
Liver international : official journal of the International Association for the Study of the Liver 2025 Dec;45(12):e70433
(-)-Guaiol Downregulates M2 Tumor-Associated Macrophage Polarization Through PPAR-γ Signaling to Suppress Lung Cancer.
Zhao ZY, Wu JC, Luo YB, Wang YL, Wang X, Tian JH, Zhang B, Li Y
Biological procedures online 2025 Dec 5;28(1):1
Biological procedures online 2025 Dec 5;28(1):1
Intestinal microbiota contributes to the heterogeneity of fat deposition by promoting mitochondrial fatty acid β-oxidation.
Li L, Zhou N, Wang Z, Wang T, Wang Y, Qiao F, Du ZY, Zhang ML
Gut microbes 2025 Dec 31;17(1):2593076
Gut microbes 2025 Dec 31;17(1):2593076
Riboflavin Increases Goat Sperm Motility via Enhancement of Mitochondrial β-Oxidation.
Wang Q, Zhang N, Sun L, Ding P, Zhao S, Ma D, Kou X, Zhu Z, Min L
Biology 2025 Dec 31;15(1)
Biology 2025 Dec 31;15(1)
Machine learning-based identification of kbhb-affected tumor cell subsets as prognostic and therapeutic targets in breast cancer.
Yuan Q, Sha Y, Ye R, Yu H, Ni L, Han J, Deng L
Journal of translational medicine 2025 Dec 11;24(1):71
Journal of translational medicine 2025 Dec 11;24(1):71
Knockdown of MiD49 and MiD51 alleviates collagen-induced arthritis and suppresses mitophagy and fatty acid oxidation (FAO) in rheumatoid arthritis fibroblast-like synoviocytes.
Liu J, Zhang C, Ma R, Yin C, Ren J, Yang S, Zhao Y, Tang Y, Wei J, Li X
Free radical biology & medicine 2025 Dec 1;240:514-531
Free radical biology & medicine 2025 Dec 1;240:514-531
Genetic algorithm-back propagation artificial neural network model- and response surface methodology-based optimization of crude Lophatherum gracile Brongn. polysaccharides extraction and their anti-NAFLD effects via regulating liver-adipose tissue crosstalk.
Wu C, Chen QC, Ni Q, Cai WF, Jiang CP, Yi YK, Liu L, Shen CY
International journal of biological macromolecules 2025 Aug;320(Pt 1):145806
International journal of biological macromolecules 2025 Aug;320(Pt 1):145806
Arachidonic acid metabolite prostaglandin E2 attenuates diethylhexyl phthalate-induced hepatotoxicity through promoting macrophage M2 polarization.
Xu M, You L, Tian Y, Yan J, Shi L, Wan Y, Jia X, Yang H, Hu W
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2025 Aug;202:115501
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2025 Aug;202:115501
Inhibiting FAT1 Blocks Metabolic Bypass to Enhance Antitumor Efficacy of TCA Cycle Inhibition through Suppressing CPT1A-Dependent Fatty Acid Oxidation.
Chen F, Yang J, Popoola DO, Yang F, Liu Y, Wang D, Qin ZS, Chen Z, Saba NF, Chen ZG, Li Y, Teng Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Aug;12(30):e02146
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Aug;12(30):e02146
FGF21-MAPK1 Imbalance Disrupts Hepatic Lipid Metabolism in Dairy Cow Ketosis.
Xu JJ, Yang F, Chen ZX, Wang ZP, Wang ZX, Deng ZH, Xu CJ, Chen FH, Zhang W, Liu Y, Cai YF
Life (Basel, Switzerland) 2025 Aug 24;15(9)
Life (Basel, Switzerland) 2025 Aug 24;15(9)
Inhibition of CPT1A activates the cGAS/STING pathway to enhance neutrophil-mediated tumor abrogation in triple-negative breast cancer.
Li C, Gao T, Zhao Q, Li Z, Wang Z, Ding S, Zhang M, Qin Y, Xue X, Zhang X, Tian G, Bian XW, Yang Y
Cancer letters 2025 Aug 16;633:217991
Cancer letters 2025 Aug 16;633:217991
Ergosterol from edible fungi: Enhancing fatty acid oxidation via CPT1A to protect against diabetic kidney disease.
Dong Z, Li X, Wang X, Xu J, Xu W
Food & function 2025 Aug 11;16(16):6599-6611
Food & function 2025 Aug 11;16(16):6599-6611
Lactobacillus murinus alleviates insulin resistance via promoting L-citrulline synthesis.
Long J, Shi Z, Miao Z, Dong L, Yan D
Journal of endocrinological investigation 2025 Apr;48(4):1005-1015
Journal of endocrinological investigation 2025 Apr;48(4):1005-1015
Targeting Histone Deacetylase 11 with a Highly Selective Inhibitor for the Treatment of MASLD.
Zhang F, Yue K, Sun S, Lu S, Jia G, Zha Y, Zhang S, Chou CJ, Liao C, Li X, Duan Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Apr;12(15):e2412903
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Apr;12(15):e2412903
Distinct Hepatic Metabolic Reprogramming in Acute and Chronic Sleep Deprivation and the Protective Effects of the Chalcone Analogue TAK.
Wang Y, Hu Y, Wang P, Hu R, Chen Z, Zhang T, Liu J, Noda M, Long J, Peng Y
International journal of molecular sciences 2025 Apr 8;26(8)
International journal of molecular sciences 2025 Apr 8;26(8)
Inhibition Mechanism of Mulberry Prenylated Flavonoids Sanggenone D/Kuwanon G Against α-Glucosidase and the Regulation of Glucose via GLUT4 Pathway.
Wu E, Zhu Y, Wei Q, Lu H, Zou Y, Liu F, Li Q
Nutrients 2025 Apr 30;17(9)
Nutrients 2025 Apr 30;17(9)
Pemafibrate modulates peroxisome proliferator-activated receptor alpha and prevents alcohol-associated liver disease in rats.
Saito T, George J, Ozaki K, Tsuchishima M, Tsutsumi M
Molecular medicine (Cambridge, Mass.) 2025 Apr 22;31(1):145
Molecular medicine (Cambridge, Mass.) 2025 Apr 22;31(1):145
Cold-Induced DHRS4 Promotes Thermogenesis via Enhanced Fatty Acid β-Oxidation in Porcine Subcutaneous Adipocytes.
Ma X, Ye Z, Li M, Wei W, Chen J, Zhang L
Animals : an open access journal from MDPI 2025 Apr 22;15(9)
Animals : an open access journal from MDPI 2025 Apr 22;15(9)
Artemether regulates liver glycogen and lipid utilization through mitochondrial pyruvate oxidation in db/db mice.
Weng W, Shen L, Yu X, Yuan R, Shao M, Han P, Sun H
American journal of translational research 2024;16(1):27-38
American journal of translational research 2024;16(1):27-38
Bushen Huoxue formula attenuates lipid accumulation evoking excessive autophagy in premature ovarian insufficiency rats and palmitic acid-challenged KGN cells by modulating lipid metabolism.
Li T, Wei Y, Jiao B, Hao R, Zhou B, Bian X, Wang P, Zhou Y, Sun X, Zhang J
Frontiers in pharmacology 2024;15:1425844
Frontiers in pharmacology 2024;15:1425844
Traditional Chinese Medicine formula Dai-Zong-Fang alleviating hepatic steatosis in db/db mice via gut microbiota modulation.
Zhang LW, Zhu LL, Zhu XY, Fu SQ, Liu XM
Frontiers in pharmacology 2024;15:1337057
Frontiers in pharmacology 2024;15:1337057
Palmitoylation of PKCδ by ZDHHC5 in hypothalamic microglia presents as a therapeutic target for fatty liver disease.
Wang YH, Chen X, Bai YZ, Gao P, Yang Z, Guo Q, Lu YY, Zheng J, Liu D, Yang J, Tu PF, Zeng KW
Theranostics 2024;14(3):988-1009
Theranostics 2024;14(3):988-1009
Identification of proteins related to SIS3 by iTRAQ and PRM-based comparative proteomic analysis in cisplatin-induced acute kidney injury.
Huang J, Ye J, Gao Y, Wang Y, Zhao Q, Lou T, Lai W
PeerJ 2024;12:e17485
PeerJ 2024;12:e17485
Valine metabolite, 3-hydroxyisobutyrate, promotes lipid metabolism and cell proliferation in porcine mammary gland epithelial cells.
Che L, Liu L, Xu M, Fan Z, Niu L, Chen Y, Chang X, Zhou P, Li M, Deng H, Chen W
Frontiers in nutrition 2024;11:1524738
Frontiers in nutrition 2024;11:1524738
Inactivation of mitochondrial MUL1 E3 ubiquitin ligase deregulates mitophagy and prevents diet-induced obesity in mice.
Cilenti L, Di Gregorio J, Mahar R, Liu F, Ambivero CT, Periasamy M, Merritt ME, Zervos AS
Frontiers in molecular biosciences 2024;11:1397565
Frontiers in molecular biosciences 2024;11:1397565
Ethanol Extract of Propolis Attenuates Liver Lipid Metabolism Disorder in High-Fat Diet-Fed SAMP8 Mice.
Xie QY, Shu X, Liu T, Chen LL, Luo LP
Molecular nutrition & food research 2024 Sep;68(17):e2400297
Molecular nutrition & food research 2024 Sep;68(17):e2400297
ACAT1 suppresses clear cell renal cell carcinoma progression by AMPK mediated fatty acid metabolism.
Zheng M, Zhang S, Zhou J, Lin M, Liao Y
Translational oncology 2024 Sep;47:102043
Translational oncology 2024 Sep;47:102043
Gentiopicroside ameliorates glucose and lipid metabolism in T2DM via targeting FGFR1.
Xu Z, Huang J, Wen M, Zhang X, Lyu D, Li S, Xiao H, Li M, Shen C, Huang H
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Sep;132:155780
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Sep;132:155780
The developmental pattern related to fatty acid uptake and oxidation in the yolk sac membrane and jejunum during embryogenesis in Muscovy duck.
Li H, Zhang X, Wang X, Wu Q, Zheng W, Liu C, Wei S, Zuo X, Xiao W, Ye H, Wang W, Yang L, Zhu Y
Poultry science 2024 Sep;103(9):103929
Poultry science 2024 Sep;103(9):103929
NR2F2 Reactivation in Early-life Adipocyte Stem-like Cells Rescues Adipocyte Mitochondrial Oxidation.
Das S, Varshney R, Farriester JW, Kyere-Davies G, Martinez AE, Hill K, Kinter M, Mullen GP, Nagareddy PR, Rudolph MC
bioRxiv : the preprint server for biology 2024 Sep 9;
bioRxiv : the preprint server for biology 2024 Sep 9;
Cpt1a Drives primed-to-naïve pluripotency transition through lipid remodeling.
Ma Z, Huang X, Kuang J, Wang Q, Qin Y, Huang T, Liang Z, Li W, Fu Y, Li P, Fan Y, Zhai Z, Wang X, Ming J, Zhao C, Wang B, Pei D
Communications biology 2024 Sep 30;7(1):1223
Communications biology 2024 Sep 30;7(1):1223
Etomoxir repurposed as a promiscuous fatty acid mimetic chemoproteomic probe.
Choi J, Smith DM, Lee YJ, Cai D, Hossain MJ, O'Connor TJ, Deme P, Haughey NJ, Scafidi S, Riddle RC, Wolfgang MJ
iScience 2024 Sep 20;27(9):110642
iScience 2024 Sep 20;27(9):110642
Clinopodium gracile Alleviates Metabolic Dysfunction-Associated Steatotic Liver Disease by Upregulating Peroxisome Proliferator-Activated Receptor α and Inhibiting Mitochondrial Oxidative Damage.
Ren M, Ren J, Zheng J, Sha X, Lin Y, Wu F
Antioxidants (Basel, Switzerland) 2024 Sep 20;13(9)
Antioxidants (Basel, Switzerland) 2024 Sep 20;13(9)
Hypothalamic SLC7A14 accounts for aging-reduced lipolysis in white adipose tissue of male mice.
Jiang X, Liu K, Luo P, Li Z, Xiao F, Jiang H, Wu S, Tang M, Yuan F, Li X, Shu Y, Peng B, Chen S, Ni S, Guo F
Nature communications 2024 Sep 11;15(1):7948
Nature communications 2024 Sep 11;15(1):7948
FABP4 deficiency ameliorates alcoholic steatohepatitis in mice via inhibition of p53 signaling pathway.
Xing H, Wu Z, Jiang K, Yuan G, Guo Z, Yu S, He S, Zhong F
Scientific reports 2024 Sep 10;14(1):21135
Scientific reports 2024 Sep 10;14(1):21135
Jujuboside A through YY1/CYP2E1 signaling alleviated type 2 diabetes-associated fatty liver disease by ameliorating hepatic lipid accumulation, inflammation, and oxidative stress.
Zhang W, Cheng Q, Yin L, Liu Y, Chen L, Jiang Z, Jiang X, Qian S, Li B, Wu M, Yin X, Wang T, Lu Q, Yang T
Chemico-biological interactions 2024 Sep 1;400:111157
Chemico-biological interactions 2024 Sep 1;400:111157
Nicotinamide mononucleotide supplementation rescues mitochondrial and energy metabolism functions and ameliorates inflammatory states in the ovaries of aging mice.
Liang J, Huang F, Hao X, Zhang P, Chen R
MedComm 2024 Oct;5(10):e727
MedComm 2024 Oct;5(10):e727
Identification of serum metabolites associated with aristolochic acid nephropathy severity and insights into the underlying mechanism.
Liu X, Peng Y, Wu S, Huang X, Gao L, Deng R, Lu J
Toxicology letters 2024 Oct;400:24-34
Toxicology letters 2024 Oct;400:24-34
Dapagliflozin attenuates AKI to CKD transition in diabetes by activating SIRT3/PGC1-α signaling and alleviating aberrant metabolic reprogramming.
Li H, Xia Y, Zha H, Zhang Y, Shi L, Wang J, Huang H, Yue R, Hu B, Zhu J, Song Z
Biochimica et biophysica acta. Molecular basis of disease 2024 Oct;1870(7):167433
Biochimica et biophysica acta. Molecular basis of disease 2024 Oct;1870(7):167433
SMYD2 Promotes Calcium Oxalate-Induced Glycolysis in Renal Tubular Epithelial Cells via PTEN Methylation.
Pan S, Yuan T, Xia Y, Yu W, Li H, Rao T, Ye Z, Li L, Zhou X, Cheng F
Biomedicines 2024 Oct 8;12(10)
Biomedicines 2024 Oct 8;12(10)
Berberine directly targets AKR1B10 protein to modulate lipid and glucose metabolism disorders in NAFLD.
Yang S, Cao SJ, Li CY, Zhang Q, Zhang BL, Qiu F, Kang N
Journal of ethnopharmacology 2024 Oct 5;332:118354
Journal of ethnopharmacology 2024 Oct 5;332:118354
Pea Albumin Alleviates Oleic Acid-Induced Lipid Accumulation in LO2 Cells Through Modulating Lipid Metabolism and Fatty Acid Oxidation Pathways.
Fang B, Luo J, Cui Z, Liu R, Wang P, Zhang J
Foods (Basel, Switzerland) 2024 Oct 30;13(21)
Foods (Basel, Switzerland) 2024 Oct 30;13(21)
MiR-21-3p inhibitor exerts myocardial protective effects by altering macrophage polarization state and reducing excessive mitophagy.
Huang Y, Huang Y, Cai Z, Ferrari MW, Li C, Zhang T, Lyu G, Wang Z
Communications biology 2024 Oct 22;7(1):1371
Communications biology 2024 Oct 22;7(1):1371
Oral Microbiome and CPT1A Function in Fatty Acid Metabolism in Oral Cancer.
Praveen Z, Choi SW, Lee JH, Park JY, Oh HJ, Kwon IJ, Park JH, Kim MK
International journal of molecular sciences 2024 Oct 10;25(20)
International journal of molecular sciences 2024 Oct 10;25(20)
Castration reshapes the liver by altering fatty acid composition and metabolism in male mice.
Yao H, Li D, Cao X, Han X, He J, Cheng D, Shang J, Song T, Zeng X
Biochemical and biophysical research communications 2024 Oct 1;727:150319
Biochemical and biophysical research communications 2024 Oct 1;727:150319
Rituximab induces ferroptosis and RSL3 overcomes rituximab resistance in diffuse large B-cell lymphoma cells.
Wu H, Zou L, Jin Y, Wang G, Cho WC, Li W, Cai Y, Song G
Archives of biochemistry and biophysics 2024 Nov;761:110188
Archives of biochemistry and biophysics 2024 Nov;761:110188
The ZNF263/CPT1B axis regulates fatty acid β-oxidation to affect cisplatin resistance in lung adenocarcinoma.
Yan R, Zheng C, Qian S, Li K, Kong X, Liao S
The pharmacogenomics journal 2024 Nov 5;24(6):33
The pharmacogenomics journal 2024 Nov 5;24(6):33
HMGB1 Modulates Macrophage Metabolism and Polarization in Ulcerative Colitis by Inhibiting Cpt1a Expression.
Wang F, Luo L, Wu Z, Wan L, Li F, Wen Z
Frontiers in bioscience (Landmark edition) 2024 Nov 19;29(11):387
Frontiers in bioscience (Landmark edition) 2024 Nov 19;29(11):387
Resistance Exercise Improves Glycolipid Metabolism and Mitochondrial Biogenesis in Skeletal Muscle of T2DM Mice via miR-30d-5p/SIRT1/PGC-1α Axis.
Zheng L, Rao Z, Wu J, Ma X, Jiang Z, Xiao W
International journal of molecular sciences 2024 Nov 19;25(22)
International journal of molecular sciences 2024 Nov 19;25(22)
Deciphering Mechanisms of Adipocyte Differentiation in Abdominal Fat of Broilers.
Sun X, Liu X, Wang C, Ren Z, Yang X, Liu Y
Journal of agricultural and food chemistry 2024 Nov 13;72(45):25403-25413
Journal of agricultural and food chemistry 2024 Nov 13;72(45):25403-25413
Androgens exacerbate hepatic triglyceride accumulation in rats with polycystic ovary syndrome by downregulating MTTP expression.
Wang D, Zhao H, Xing C, Lv B, Wang X, He B
Endocrine 2024 May;84(2):735-744
Endocrine 2024 May;84(2):735-744
A combined nanotherapeutic approach targeting farnesoid X receptor, ferroptosis, and fibrosis for nonalcoholic steatohepatitis treatment.
Fu J, Zhang P, Sun Z, Lu G, Cao Q, Chen Y, Wu W, Zhang J, Zhuang C, Sheng C, Xu J, Lu Y, Wang P
Acta pharmaceutica Sinica. B 2024 May;14(5):2228-2246
Acta pharmaceutica Sinica. B 2024 May;14(5):2228-2246
Probiotic-fermented tomato with hepatic lipid metabolism modulation effects: analysis of physicochemical properties, bioactivities, and potential bioactive compounds.
Wei B, Zheng W, Peng Z, Xiao M, Huang T, Xie M, Xiong T
Food & function 2024 May 7;15(9):4874-4886
Food & function 2024 May 7;15(9):4874-4886
Transgenic female mice producing trans 10, cis 12-conjugated linoleic acid present excessive prostaglandin E2, adrenaline, corticosterone, glucagon, and FGF21.
Rao Y, Liang LW, Li MJ, Wang YY, Wang BZ, Gou KM
Scientific reports 2024 May 30;14(1):12430
Scientific reports 2024 May 30;14(1):12430
APC/C-regulated CPT1C promotes tumor progression by upregulating the energy supply and accelerating the G1/S transition.
Zhao H, Cheng X, Yan L, Mi F, Wang W, Hu Y, Liu X, Fan Y, Min Q, Wang Y, Zhang W, Wu Q, Zhan Q
Cell communication and signaling : CCS 2024 May 23;22(1):283
Cell communication and signaling : CCS 2024 May 23;22(1):283
BNIP3 in hypoxia-induced mitophagy: Novel insights and promising target for non-alcoholic fatty liver disease.
Tian M, Hou J, Liu Z, Li Z, Huang D, Zhang Y, Ma Y
The international journal of biochemistry & cell biology 2024 Mar;168:106517
The international journal of biochemistry & cell biology 2024 Mar;168:106517
Targeting carnitine palmitoyl transferase 1A (CPT1A) induces ferroptosis and synergizes with immunotherapy in lung cancer.
Ma L, Chen C, Zhao C, Li T, Ma L, Jiang J, Duan Z, Si Q, Chuang TH, Xiang R, Luo Y
Signal transduction and targeted therapy 2024 Mar 7;9(1):64
Signal transduction and targeted therapy 2024 Mar 7;9(1):64
Targeting Erbin-mitochondria axis in platelets/megakaryocytes promotes B cell-mediated antitumor immunity.
Zhang Z, Xu X, Zhang D, Zhao S, Wang C, Zhang G, Chen W, Liu J, Gong H, Rixiati Y, Li S, Shen T, Li J
Cell metabolism 2024 Mar 5;36(3):541-556.e9
Cell metabolism 2024 Mar 5;36(3):541-556.e9
Pennogenin 3-O-β-Chacotrioside Attenuates Hypertrophied Lipid Accumulation by Enhancing Mitochondrial Oxidative Capacity.
Yu S, Lee HM, Lee J, Hwang JT, Choi HK, Lee YG
International journal of molecular sciences 2024 Mar 4;25(5)
International journal of molecular sciences 2024 Mar 4;25(5)
5-Heptadecylresorcinol Improves Aging-Associated Hepatic Fatty Acid Oxidation Dysfunction via Regulating Adipose Sirtuin 3.
Zhang K, Jiang L, Xue L, Wang Y, Sun Y, Fan M, Qian H, Wang L, Li Y
Nutrients 2024 Mar 27;16(7)
Nutrients 2024 Mar 27;16(7)
Screening of CPT1A-Targeting Lipid Metabolism Modulators Using Mitochondrial Membrane Chromatography.
Su W, Xu F, Zhong J, Hu R, Wang L, Li H, Yang Z, Ge S, He H, Han S, Xie X, Guo H, He L, Liu J, Yi T, Kong Y, Long J
ACS applied materials & interfaces 2024 Mar 13;16(10):13234-13246
ACS applied materials & interfaces 2024 Mar 13;16(10):13234-13246
Testosterone regulates thymic remodeling by altering metabolic reprogramming in male rats.
Li D, Yao H, Ren Y, Shang J, Han X, Cao X, Song T, Zeng X
General and comparative endocrinology 2024 Mar 1;348:114448
General and comparative endocrinology 2024 Mar 1;348:114448
miR-1268a Regulates Fatty Acid Metabolism by Targeting CD36 in Angiotensin II-induced Heart Failure.
Xu G, Xu Y, Zhang Y, Kao G, Li J
Cell biochemistry and biophysics 2024 Jun;82(2):1193-1201
Cell biochemistry and biophysics 2024 Jun;82(2):1193-1201
Mechanistic of AMPK/ACC2 regulating myoblast differentiation by fatty acid oxidation of goat.
Kang Z, Zhang Z, Li J, Deng K, Wang F, Fan Y
International journal of biological macromolecules 2024 Jun;270(Pt 2):132243
International journal of biological macromolecules 2024 Jun;270(Pt 2):132243
Deficiency of SDHC promotes metastasis by reprogramming fatty acid metabolism in colorectal cancer.
Ding Z, Wei Y, Dai J, Pan C, Yang L, Li Q, Zhang Y, Yan Q, Wu C, Li A, Lan Z, Liu S, Wang X
Journal of translational medicine 2024 Jun 6;22(1):544
Journal of translational medicine 2024 Jun 6;22(1):544
Chrysanthemum morifolium Ramat extract and probiotics combination ameliorates metabolic disorders through regulating gut microbiota and PPARα subcellular localization.
Gao X, Zhu Z, Bao Y, Li Y, Zhu W, He X, Ge X, Huang W, Wang H, Wei W, Du J, Chen L, Li H, Sheng L
Chinese medicine 2024 Jun 3;19(1):76
Chinese medicine 2024 Jun 3;19(1):76
Penthorum chinense Pursh extract ameliorates alcohol-related fatty liver disease in mice via the SIRT1/AMPK signaling axis.
Zhuge H, Pan Y, Lai S, Chang K, Ding Q, Cao W, Song Q, Li S, Dou X, Ding B
Heliyon 2024 Jun 15;10(11):e31195
Heliyon 2024 Jun 15;10(11):e31195
Redistribution of defective mitochondria-mediated dihydroorotate dehydrogenase imparts 5-fluorouracil resistance in colorectal cancer.
Dong S, Zhang M, Cheng Z, Zhang X, Liang W, Li S, Li L, Xu Q, Song S, Liu Z, Yang G, Zhao X, Tao Z, Liang S, Wang K, Zhang G, Hu S
Redox biology 2024 Jul;73:103207
Redox biology 2024 Jul;73:103207
Tamoxifen upregulates the peroxisomal β-oxidation enzyme Enoyl CoA hydratase and 3-hydroxyacyl CoA hydratase ameliorating hepatic lipid accumulation in mice.
Zhang Z, Yang Q, Jin M, Wang J, Chai Y, Zhang L, Jiang Z, Yu Q
The international journal of biochemistry & cell biology 2024 Jul;172:106585
The international journal of biochemistry & cell biology 2024 Jul;172:106585
Regulation of astrocyte metabolism by mitochondrial translocator protein 18 kDa.
Firth W, Robb JL, Stewart D, Pye KR, Bamford R, Oguro-Ando A, Beall C, Ellacott KLJ
Journal of neurochemistry 2024 Jul;168(7):1374-1401
Journal of neurochemistry 2024 Jul;168(7):1374-1401
Luteolin alleviates cadmium-induced metabolism disorder through antioxidant and anti-inflammatory mechanisms in chicken kidney.
Wang X, Zhang K, Ali W, Li J, Huang Q, Liu D, Liu G, Ran D, Liu Z
Poultry science 2024 Jul;103(7):103817
Poultry science 2024 Jul;103(7):103817
Lactobacillus rhamnosus NKU FL1-8 Isolated from Infant Feces Ameliorates the Alcoholic Liver Damage by Regulating the Gut Microbiota and Intestinal Barrier in C57BL/6J Mice.
Liu H, Fan D, Wang J, Wang Y, Li A, Wu S, Zhang B, Liu J, Wang S
Nutrients 2024 Jul 4;16(13)
Nutrients 2024 Jul 4;16(13)
Structural Variances in Curcumin Degradants: Impact on Obesity in Mice.
Koh YC, Hsu HW, Ho PY, Hsu KY, Lin WS, Nagabhushanam K, Ho CT, Pan MH
Journal of agricultural and food chemistry 2024 Jul 3;72(26):14786-14798
Journal of agricultural and food chemistry 2024 Jul 3;72(26):14786-14798
CPT1A loss disrupts BCAA metabolism to confer therapeutic vulnerability in TP53-mutated liver cancer.
Liu Y, Wang F, Yan G, Tong Y, Guo W, Li S, Qian Y, Li Q, Shu Y, Zhang L, Zhang Y, Xia Q
Cancer letters 2024 Jul 28;595:217006
Cancer letters 2024 Jul 28;595:217006
Ginsenoside Rb1 regulates CPT1A deacetylation to inhibit intramuscular fat infiltration after rotator cuff tear.
Yin Y, Wang Z, Yang Y, Shen M, Hu H, Chen C, Zhou H, Li Z, Wu S
iScience 2024 Jul 19;27(7):110331
iScience 2024 Jul 19;27(7):110331
Hypoxia induces mitochondrial protein lactylation to limit oxidative phosphorylation.
Mao Y, Zhang J, Zhou Q, He X, Zheng Z, Wei Y, Zhou K, Lin Y, Yu H, Zhang H, Zhou Y, Lin P, Wu B, Yuan Y, Zhao J, Xu W, Zhao S
Cell research 2024 Jan;34(1):13-30
Cell research 2024 Jan;34(1):13-30
Effects of hazelnut soluble dietary fiber on lipid-lowering and gut microbiota in high-fat-diet-fed rats.
Lin H, Li J, Sun M, Wang X, Zhao J, Zhang W, Lv G, Wang Y, Lin Z
International journal of biological macromolecules 2024 Jan;256(Pt 2):128538
International journal of biological macromolecules 2024 Jan;256(Pt 2):128538
Prunella vulgaris L. attenuates gut dysbiosis and endotoxin leakage against alcoholic liver disease.
Rao PL, Shen YH, Song YJ, Xu Y, Xu HX
Journal of ethnopharmacology 2024 Jan 30;319(Pt 2):117237
Journal of ethnopharmacology 2024 Jan 30;319(Pt 2):117237
Endogenous Coriobacteriaceae enriched by a high-fat diet promotes colorectal tumorigenesis through the CPT1A-ERK axis.
Tang Q, Huang H, Xu H, Xia H, Zhang C, Ye D, Bi F
NPJ biofilms and microbiomes 2024 Jan 20;10(1):5
NPJ biofilms and microbiomes 2024 Jan 20;10(1):5
Exploring the mechanism and phytochemicals in Psoraleae Fructus-induced hepatotoxicity based on RNA-seq, in vitro screening and molecular docking.
Shang H, Liu X, Pan J, Cheng H, Ma Z, Xiao C, Gao Y
Scientific reports 2024 Jan 19;14(1):1696
Scientific reports 2024 Jan 19;14(1):1696
Acetyl-CoA synthetase 2 promotes diabetic renal tubular injury in mice by rewiring fatty acid metabolism through SIRT1/ChREBP pathway.
Lu J, Li XQ, Chen PP, Zhang JX, Li L, Wang GH, Liu XQ, Jiang CM, Ma KL
Acta pharmacologica Sinica 2024 Feb;45(2):366-377
Acta pharmacologica Sinica 2024 Feb;45(2):366-377
Hypoxia induced cell dormancy of salivary adenoid cystic carcinoma through miR-922/DEC2 axis.
Dai L, Xian H, Wang H, Li M, Zhang M, Liang XH, Tang YL
Translational oncology 2024 Feb;40:101868
Translational oncology 2024 Feb;40:101868
FXR overexpression prevents hepatic steatosis through inhibiting AIM2 inflammasome activation in alcoholic liver disease.
Li L, Kong L, Xu S, Wang C, Gu J, Luo H, Meng Q
Hepatology international 2024 Feb;18(1):188-205
Hepatology international 2024 Feb;18(1):188-205
ACACA reduces lipid accumulation through dual regulation of lipid metabolism and mitochondrial function via AMPK- PPARα- CPT1A axis.
Dong J, Li M, Peng R, Zhang Y, Qiao Z, Sun N
Journal of translational medicine 2024 Feb 23;22(1):196
Journal of translational medicine 2024 Feb 23;22(1):196
Mitochondrial apolipoprotein MIC26 is a metabolic rheostat regulating central cellular fuel pathways.
Damiecki M, Naha R, Schaumkessel Y, Westhoff P, Atanelov N, Stefanski A, Petzsch P, Stühler K, Köhrer K, Weber AP, Anand R, Reichert AS, Kondadi AK
Life science alliance 2024 Dec;7(12)
Life science alliance 2024 Dec;7(12)
Chlorogenic acid alleviates renal fibrosis by reducing lipid accumulation in diabetic kidney disease through suppressing the Notch1 and Stat3 signaling pathway.
Yang XY, Jiang D, Wang YZ, Duan MY, Huang YW, Wang XJ, Xiang ZM, Sheng J, Zhu QQ
Renal failure 2024 Dec;46(2):2371988
Renal failure 2024 Dec;46(2):2371988
Attenuation of high-fat diet-induced weight gain by apolipoprotein A4.
Kuo HN, LaRussa Z, Xu FM, Consitt LA, Liu M, Davidson WS, Puri V, Coschigano KT, Shi H, Lo CC
Obesity (Silver Spring, Md.) 2024 Dec;32(12):2321-2333
Obesity (Silver Spring, Md.) 2024 Dec;32(12):2321-2333
Sirt1-mediated deacetylation of PGC-1α alleviated hepatic steatosis in type 2 diabetes mellitus via improving mitochondrial fatty acid oxidation.
Pang J, Yin L, Jiang W, Wang H, Cheng Q, Jiang Z, Cao Y, Zhu X, Li B, Qian S, Yin X, Wang T, Lu Q, Yang T
Cellular signalling 2024 Dec;124:111478
Cellular signalling 2024 Dec;124:111478
N6-methyladenosine regulates metabolic remodeling in kidney aging through transcriptional regulator GLIS1.
Xu L, Chen S, Fan Q, Zhu Y, Mei H, Wang J, Yu H, Chen Y, Liu F
BMC biology 2024 Dec 31;22(1):302
BMC biology 2024 Dec 31;22(1):302
N1-methyladenosine RNA methylation patterns are associated with an increased risk to biochemical recurrence in prostate cancer and serve as a potential novel biomarker for patient stratification.
Deng Y, Tan Z, Cai S, Feng Y, Tang Z, Li J, He H, Wu Z, Liu R, Huang H, Ye J, Han Z, Zhong W
International immunopharmacology 2024 Dec 25;143(Pt 2):113404
International immunopharmacology 2024 Dec 25;143(Pt 2):113404
Carnitine palmitoyltransferase 1 facilitates fatty acid oxidation in a non-cell-autonomous manner.
Choi J, Smith DM, Scafidi S, Riddle RC, Wolfgang MJ
Cell reports 2024 Dec 24;43(12):115006
Cell reports 2024 Dec 24;43(12):115006
Protective Effects of Dioscin and Diosgenin on Plateau Hyperuricemia by Attenuating Renal Inflammation via EPHX2.
Dang W, Li F, Gao R, Zhang C, Cheng H, Wu Z, Yang T, Pan J, Tang X, Gao Y
International journal of molecular sciences 2024 Dec 13;25(24)
International journal of molecular sciences 2024 Dec 13;25(24)
CD9 Counteracts Liver Steatosis and Mediates GCGR Agonist Hepatic Effects.
Zheng Y, Wang Y, Xiong X, Zhang L, Zhu J, Huang B, Liu X, Liu J, Zhu Z, Yang G, Qu H, Zheng H
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Aug;11(29):e2400819
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Aug;11(29):e2400819
CircHIPK3/miR-124 affects angiogenesis in early-onset preeclampsia via CPT1A-mediated fatty acid oxidation.
Wu Y, Huang J, Liu L, Zhang X, Zhang W, Li Q
Journal of molecular medicine (Berlin, Germany) 2024 Aug;102(8):1037-1049
Journal of molecular medicine (Berlin, Germany) 2024 Aug;102(8):1037-1049
Regulatory effect of β-glucan secreted by Rhizobium pusense on triglyceride metabolism and their relationships with the modulation of intestinal microbiota in mice fed a high-fat diet.
Zhang B, Zhao W, Song D, Lyu X
Food & function 2024 Aug 27;15(17):8759-8774
Food & function 2024 Aug 27;15(17):8759-8774
Cryptotanshinone alleviates liver fibrosis via inhibiting STAT3/CPT1A-dependent fatty acid oxidation in hepatic stellate cells.
Li Z, Zheng Y, Zhang L, Xu E
Chemico-biological interactions 2024 Aug 25;399:111119
Chemico-biological interactions 2024 Aug 25;399:111119
Moderate replacement of fish oil with palmitic acid-stimulated mitochondrial fusion promotes β-oxidation by Mfn2 interacting with Cpt1α via its GTPase-domain.
Song YF, Wang LJ, Luo Z, Hogstrand C, Lai XH, Zheng FF
The Journal of nutritional biochemistry 2024 Apr;126:109559
The Journal of nutritional biochemistry 2024 Apr;126:109559
Targeting hepatic ceruloplasmin mitigates nonalcoholic steatohepatitis by modulating bile acid metabolism.
Jiang Q, Wang N, Lu S, Xiong J, Yuan Y, Liu J, Chen S
Journal of molecular cell biology 2024 Apr 4;15(9)
Journal of molecular cell biology 2024 Apr 4;15(9)
Beneficial Effects of High-Intensity Interval Training and Dietary Changes Intervention on Hepatic Fat Accumulation in HFD-Induced Obese Rats.
Yuan XM, Xiang MQ, Ping Y, Zhang PW, Liu YT, Liu XW, Wei J, Tang Q, Zhang Y
Physiological research 2024 Apr 30;73(2):273-284
Physiological research 2024 Apr 30;73(2):273-284
C6orf15 promotes liver metastasis via WNT/β-catenin signalling in colorectal cancer.
Yu J, Sun J, Tang J, Xu J, Qian G, Zhou J
Cancer cell international 2024 Apr 23;24(1):146
Cancer cell international 2024 Apr 23;24(1):146
Complexes of Soluble Dietary Fiber and Polyphenols from Lotus Root Regulate High-Fat Diet-Induced Hyperlipidemia in Mice.
Zheng Z, Gao W, Zhu Z, Li S, Chen X, Cravotto G, Sui Y, Zhou L
Antioxidants (Basel, Switzerland) 2024 Apr 16;13(4)
Antioxidants (Basel, Switzerland) 2024 Apr 16;13(4)
Herpetrione, a New Type of PPARα Ligand as a Therapeutic Strategy Against Nonalcoholic Steatohepatitis.
Linghu L, Zong W, Liao Y, Chen Q, Meng F, Wang G, Liao Z, Lan X, Chen M
Research (Washington, D.C.) 2023;6:0276
Research (Washington, D.C.) 2023;6:0276
Loss of PPARα function promotes epigenetic dysregulation of lipid homeostasis driving ferroptosis and pyroptosis lipotoxicity in metabolic dysfunction associated Steatotic liver disease (MASLD).
Theys C, Vanderhaeghen T, Van Dijck E, Peleman C, Scheepers A, Ibrahim J, Mateiu L, Timmermans S, Vanden Berghe T, Francque SM, Van Hul W, Libert C, Vanden Berghe W
Frontiers in molecular medicine 2023;3:1283170
Frontiers in molecular medicine 2023;3:1283170
Dihydroartemisinin Potentiates VEGFR-TKIs Antitumorigenic Effect on Osteosarcoma by Regulating Loxl2/VEGFA Expression and Lipid Metabolism Pathway.
Ding X, Zhang Y, Liang J, Li Q, Hu H, Zhou Y, Zhang B
Journal of Cancer 2023;14(5):809-820
Journal of Cancer 2023;14(5):809-820
Dapagliflozin alleviates renal fibrosis in a mouse model of adenine-induced renal injury by inhibiting TGF-β1/MAPK mediated mitochondrial damage.
Zeng J, Huang H, Zhang Y, Lv X, Cheng J, Zou SJ, Han Y, Wang S, Gong L, Peng Z
Frontiers in pharmacology 2023;14:1095487
Frontiers in pharmacology 2023;14:1095487
FDXR drives primary and endocrine-resistant tumor cell growth in ER+ breast cancer via CPT1A-mediated fatty acid oxidation.
Yan C, Gao R, Gao C, Hong K, Cheng M, Liu X, Zhang Q, Zhang J
Frontiers in oncology 2023;13:1105117
Frontiers in oncology 2023;13:1105117
Berberine alleviates non-alcoholic hepatic steatosis partially by promoting SIRT1 deacetylation of CPT1A in mice.
Wang P, Li R, Li Y, Tan S, Jiang J, Liu H, Wei X
Gastroenterology report 2023;11:goad032
Gastroenterology report 2023;11:goad032
Sustained IP3-linked Ca(2+) signaling promotes progression of triple negative breast cancer cells by regulating fatty acid metabolism.
Filadi R, De Mario A, Audano M, Romani P, Pedretti S, Cardenas C, Dupont S, Mammucari C, Mitro N, Pizzo P
Frontiers in cell and developmental biology 2023;11:1071037
Frontiers in cell and developmental biology 2023;11:1071037
Double-edged effect of sodium citrate in Nile tilapia (Oreochromis niloticus): Promoting lipid and protein deposition vs. causing hyperglycemia and insulin resistance.
Wang JX, Qiao F, Zhang ML, Chen LQ, Du ZY, Luo Y
Animal nutrition (Zhongguo xu mu shou yi xue hui) 2023 Sep;14:303-314
Animal nutrition (Zhongguo xu mu shou yi xue hui) 2023 Sep;14:303-314
γ-glutamylcysteine alleviates insulin resistance and hepatic steatosis by regulating adenylate cyclase and IGF-1R/IRS1/PI3K/Akt signaling pathways.
Zhou J, Shi Y, Yang C, Lu S, Zhao L, Liu X, Zhou D, Luo L, Yin Z
The Journal of nutritional biochemistry 2023 Sep;119:109404
The Journal of nutritional biochemistry 2023 Sep;119:109404
Metabolic characteristics of voriconazole - Induced liver injury in rats.
Du Q, Teng M, Yang L, Meng C, Qiu Y, Wang C, Chen J, Wang T, Chen S, Luo Y, Sun J, Dong Y
Chemico-biological interactions 2023 Sep 25;383:110693
Chemico-biological interactions 2023 Sep 25;383:110693
Hepatic conversion of acetyl-CoA to acetate plays crucial roles in energy stress.
Wang J, Wen Y, Zhao W, Zhang Y, Lin F, Ouyang C, Wang H, Yao L, Ma H, Zhuo Y, Huang H, Shi X, Feng L, Lin D, Jiang B, Li Q
eLife 2023 Oct 30;12
eLife 2023 Oct 30;12
Chlorogenic Acid from Burdock Roots Ameliorates Oleic Acid-Induced Steatosis in HepG2 Cells through AMPK/ACC/CPT-1 Pathway.
Ma K, Sheng W, Song X, Song J, Li Y, Huang W, Liu Y
Molecules (Basel, Switzerland) 2023 Oct 25;28(21)
Molecules (Basel, Switzerland) 2023 Oct 25;28(21)
WTAP boosts lipid oxidation and induces diabetic cardiac fibrosis by enhancing AR methylation.
Song K, Sun H, Tu B, Zhou Y, Lin LC, Liu ZY, Li R, Yang JJ, Zhang Y, Zhao JY, Tao H
iScience 2023 Oct 20;26(10):107931
iScience 2023 Oct 20;26(10):107931
Metabolic and functional remodeling of colonic macrophages in response to high-fat diet-induced obesity.
Castoldi A, Sanin DE, van Teijlingen Bakker N, Aguiar CF, de Brito Monteiro L, Rana N, Grzes KM, Kabat AM, Curtis J, Cameron AM, Caputa G, Antônio de Souza T, Souto FO, Buescher JM, Edwards-Hicks J, Pearce EL, Pearce EJ, Saraiva Camara NO
iScience 2023 Oct 20;26(10):107719
iScience 2023 Oct 20;26(10):107719
C3aR Antagonist Alleviates C3a Induced Tubular Profibrotic Phenotype Transition via Restoring PPARα/CPT-1α Mediated Mitochondrial Fatty Acid Oxidation in Renin-Dependent Hypertension.
Wang C, Wang Z, Xu J, Ma H, Jin K, Xu T, Pan X, Feng X, Zhang W
Frontiers in bioscience (Landmark edition) 2023 Oct 17;28(10):238
Frontiers in bioscience (Landmark edition) 2023 Oct 17;28(10):238
Korean red ginseng formula attenuates non-alcoholic fatty liver disease in oleic acid-induced HepG2 cells and high-fat diet-induced rats.
Zheng M, Li Y, Dong Z, Zhang Y, Xi Z, Yuan M, Xu H
Heliyon 2023 Nov;9(11):e21846
Heliyon 2023 Nov;9(11):e21846
Letter comments on: Google, ChatGPT and breast reconstruction.
Kleebayoon A, Wiwanitkit V
Journal of plastic, reconstructive & aesthetic surgery : JPRAS 2023 Nov;86:269-270
Journal of plastic, reconstructive & aesthetic surgery : JPRAS 2023 Nov;86:269-270
Voltage-dependent anion channel 1 (VDAC1) overexpression alleviates cardiac fibroblast activation in cardiac fibrosis via regulating fatty acid metabolism.
Tian G, Zhou J, Quan Y, Kong Q, Li J, Xin Y, Wu W, Tang X, Liu X
Redox biology 2023 Nov;67:102907
Redox biology 2023 Nov;67:102907
Chitobiose exhibited a lipid-lowering effect in ob/ob(-/-) mice via butyric acid enrolled liver-gut crosstalk.
Zhuang X, Zhao M, Ji X, Yang S, Yin H, Zhao L
Bioresources and bioprocessing 2023 Nov 9;10(1):79
Bioresources and bioprocessing 2023 Nov 9;10(1):79
PBRM1 mutation and WDR72 expression as potential combinatorial biomarker for predicting the response to Nivolumab in patients with ccRCC: a tumor marker prognostic study.
Chang Q, Sun J, Zhao S, Li L, Zhang N, Yan L, Fan Y, Liu J
Aging 2023 Nov 30;15(23):13753-13775
Aging 2023 Nov 30;15(23):13753-13775
Lactoferrin Alleviates Ethanol-Induced Injury via Promoting Nrf2 Nuclear Translocation in BRL-3A Rat Liver Cells.
Li D, Ding L, Yan Y, Xing Y, Xu J, Qin L
International journal of molecular sciences 2023 Nov 28;24(23)
International journal of molecular sciences 2023 Nov 28;24(23)
Resensitizing Paclitaxel-Resistant Ovarian Cancer via Targeting Lipid Metabolism Key Enzymes CPT1A, SCD and FASN.
Ma Q, Liu Z, Wang T, Zhao P, Liu M, Wang Y, Zhao W, Yuan Y, Li S
International journal of molecular sciences 2023 Nov 19;24(22)
International journal of molecular sciences 2023 Nov 19;24(22)
Calponin 2 harnesses metabolic reprogramming to determine kidney fibrosis.
Gui Y, Wang Y, Palanza Z, Wang JL, Gupta P, Tao J, Qiao Y, Hargis G, Kreutzer DL, Bastacky SI, Yu Y, Wang Y, Liu S, Fu H, Zhou D
Molecular metabolism 2023 May;71:101712
Molecular metabolism 2023 May;71:101712
Organelle interactions compartmentalize hepatic fatty acid trafficking and metabolism.
Najt CP, Adhikari S, Heden TD, Cui W, Gansemer ER, Rauckhorst AJ, Markowski TW, Higgins L, Kerr EW, Boyum MD, Alvarez J, Brunko S, Mehra D, Puchner EM, Taylor EB, Mashek DG
Cell reports 2023 May 30;42(5):112435
Cell reports 2023 May 30;42(5):112435
L-carnitine alleviates synovitis in knee osteoarthritis by regulating lipid accumulation and mitochondrial function through the AMPK-ACC-CPT1 signaling pathway.
Liao T, Mei W, Zhang L, Ding L, Yang N, Wang P, Zhang L
Journal of orthopaedic surgery and research 2023 May 26;18(1):386
Journal of orthopaedic surgery and research 2023 May 26;18(1):386
Apolipoprotein A4 Elevates Sympathetic Activity and Thermogenesis in Male Mice.
Kuo HN, LaRussa Z, Xu FM, West K, Consitt L, Davidson WS, Liu M, Coschigano KT, Shi H, Lo CC
Nutrients 2023 May 26;15(11)
Nutrients 2023 May 26;15(11)
Vinyl chloride enhances high-fat diet-induced proteome alterations in the mouse pancreas related to metabolic dysfunction.
Ge Y, Bruno M, Nash MS, Coates NH, Chorley BN, Cave MC, Beier JI
Toxicological sciences : an official journal of the Society of Toxicology 2023 May 12;193(1):103-114
Toxicological sciences : an official journal of the Society of Toxicology 2023 May 12;193(1):103-114
Metrnl Alleviates Lipid Accumulation by Modulating Mitochondrial Homeostasis in Diabetic Nephropathy.
Zhou Y, Liu L, Jin B, Wu Y, Xu L, Chang X, Hu L, Wang G, Huang Y, Song L, Zhang T, Wang Y, Xiao Y, Zhang F, Shi M, Liu L, Wang T, Yan R, Guo B
Diabetes 2023 May 1;72(5):611-626
Diabetes 2023 May 1;72(5):611-626
Developmental changes in lipid and fatty acid metabolism and the inhibition by in ovo feeding oleic acid in Muscovy duck embryogenesis.
Zhang X, Wu Q, Zheng W, Liu C, Huang L, Zuo X, Xiao W, Han X, Ye H, Wang W, Yang L, Zhu Y
Animal nutrition (Zhongguo xu mu shou yi xue hui) 2023 Mar;12:321-333
Animal nutrition (Zhongguo xu mu shou yi xue hui) 2023 Mar;12:321-333
Complementary hepatic metabolomics and proteomics reveal the adaptive mechanisms of dairy cows to the transition period.
Zhang J, Gaowa N, Wang Y, Li H, Cao Z, Yang H, Zhang X, Li S
Journal of dairy science 2023 Mar;106(3):2071-2088
Journal of dairy science 2023 Mar;106(3):2071-2088
CPT1A modulates PI3K/Akt/mTOR pathway to promote preeclampsia.
Chen M, Chao B, Xu J, Liu Z, Tao Y, He J, Wang J, Yang H, Luo X, Qi H
Placenta 2023 Mar 3;133:23-31
Placenta 2023 Mar 3;133:23-31
Extraction, characterization, and anti-nonalcoholic steatohepatitis activity of a (1,3) (1,6)-β-D-glucan from the Polyporus umbellatus (Pers.) Fries.
Gao W, Zhang L, Wu J, Xu Y, Qi S, Liu W, Liu P, Shi S, Wang H, Zhang Q, Wang Y, Wang S
International journal of biological macromolecules 2023 Mar 1;230:123252
International journal of biological macromolecules 2023 Mar 1;230:123252
Mettl3-mediated m(6)A modification plays a role in lipid metabolism disorders and progressive liver damage in mice by regulating lipid metabolism-related gene expression.
Dai G, Huang S, Li Y, Tu X, Xia J, Zhou Z, Chen W, Zhang A, Lin J, Li Y, He D, Lin T, Cong J, Lei Y, Han L, Yao Z, Liu W, Zhou Y, Li Q, Li J, Zhang Y, Wu A, Xiao D, Wang W, Zhao W, Jia J, Lin X
Aging 2023 Jun 16;15(12):5550-5568
Aging 2023 Jun 16;15(12):5550-5568
Human umbilical cord mesenchymal stem cell-derived exosomes ameliorate liver steatosis by promoting fatty acid oxidation and reducing fatty acid synthesis.
Yang F, Wu Y, Chen Y, Xi J, Chu Y, Jin J, Yan Y
JHEP reports : innovation in hepatology 2023 Jul;5(7):100746
JHEP reports : innovation in hepatology 2023 Jul;5(7):100746
Changes to PUFA-PPAR pathway during mesaconitine induced myocardial coagulative necrosis.
Chen Q, Deng X, Zhang K, Kang Y, Jiao M, Zhang J, Wang C, Li F
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Jul;177:113831
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Jul;177:113831
Cassiae Semen improves non-alcoholic fatty liver disease through autophagy-related pathway.
Ding M, Zhou F, Li Y, Liu C, Gu Y, Wu J, Fan G, Li Y, Li X
Chinese herbal medicines 2023 Jul;15(3):421-429
Chinese herbal medicines 2023 Jul;15(3):421-429
Modulation of the Microbiome-Fat-Liver Axis by Lactic Acid Bacteria: A Potential Alleviated Role in High-Fat-Diet-Induced Obese Mice.
Wei B, Peng Z, Xiao M, Huang T, Yang S, Liu K, Wu M, Zheng W, Xie M, Xiong T
Journal of agricultural and food chemistry 2023 Jul 12;71(27):10361-10374
Journal of agricultural and food chemistry 2023 Jul 12;71(27):10361-10374
High-intensity interval training induces renal injury and fibrosis in type 2 diabetic mice.
Zheng L, Qin R, Rao Z, Xiao W
Life sciences 2023 Jul 1;324:121740
Life sciences 2023 Jul 1;324:121740
Hepatic DKK1-driven steatosis is CD36 dependent.
Yang Z, Huang X, Zhang J, You K, Xiong Y, Fang J, Getachew A, Cheng Z, Yu X, Wang Y, Wu F, Wang N, Feng S, Lin X, Yang F, Chen Y, Wei H, Li YX
Life science alliance 2023 Jan;6(1)
Life science alliance 2023 Jan;6(1)
Sclareol ameliorates liver injury by inhibiting nuclear factor-kappa B/NOD-like receptor protein 3-mediated inflammation and lipid metabolism disorder in diabetic mice.
Tang L, Mei X, Ye M, Liu Y, Huang Y, Yu J, Zhang L, Zhuge S, Jiang G, Zhu J
International journal of immunopathology and pharmacology 2023 Jan-Dec;37:3946320231223644
International journal of immunopathology and pharmacology 2023 Jan-Dec;37:3946320231223644
Ketogenic Diet Combined with Moderate Aerobic Exercise Training Ameliorates White Adipose Tissue Mass, Serum Biomarkers, and Hepatic Lipid Metabolism in High-Fat Diet-Induced Obese Mice.
Yan J, Ren C, Dong Y, Wali JA, Song H, Zhang Y, Zhang H, Kou G, Raubenheimer D, Cui Z
Nutrients 2023 Jan 3;15(1)
Nutrients 2023 Jan 3;15(1)
Dietary l-carnitine regulates liver lipid metabolism via simultaneously activating fatty acid β-oxidation and suppressing endoplasmic reticulum stress in large yellow croaker fed with high-fat diets.
Li JM, Zhang Z, Kong A, Lai W, Xu W, Cao X, Zhao M, Li J, Shentu J, Guo X, Mai K, Ai Q
The British journal of nutrition 2023 Jan 14;129(1):29-40
The British journal of nutrition 2023 Jan 14;129(1):29-40
PPARα agonist fenofibrate prevents postoperative cognitive dysfunction by enhancing fatty acid oxidation in mice.
Liu T, Chen X, Wei Z, Han X, Liu Y, Ma Z, Xia T, Gu X
Translational neuroscience 2023 Jan 1;14(1):20220317
Translational neuroscience 2023 Jan 1;14(1):20220317
Gene therapy targeting miR‑212‑3p exerts therapeutic effects on MAFLD similar to those of exercise.
Sun B, Zhang Y, Zhang M, Liu R, Yang W
International journal of molecular medicine 2023 Feb;51(2)
International journal of molecular medicine 2023 Feb;51(2)
High cholesterol intake remodels cholesterol turnover and energy homeostasis in Nile tilapia (Oreochromis niloticus).
Li RX, Chen LY, Limbu SM, Qian YC, Zhou WH, Chen LQ, Luo Y, Qiao F, Zhang ML, Du ZY
Marine life science & technology 2023 Feb;5(1):56-74
Marine life science & technology 2023 Feb;5(1):56-74
Malonyl-CoA Accumulation as a Compensatory Cytoprotective Mechanism in Cardiac Cells in Response to 7-Ketocholesterol-Induced Growth Retardation.
Cheng ML, Yang CH, Wu PT, Li YC, Sun HW, Lin G, Ho HY
International journal of molecular sciences 2023 Feb 23;24(5)
International journal of molecular sciences 2023 Feb 23;24(5)
Is There a Role of Warburg Effect in Prostate Cancer Aggressiveness? Analysis of Expression of Enzymes of Lipidic Metabolism by Immunohistochemistry in Prostate Cancer Patients (DIAMOND Study).
Russo GI, Asmundo MG, Lo Giudice A, Trefiletti G, Cimino S, Ferro M, Lombardo R, De Nunzio C, Morgia G, Piombino E, Failla M, Caltabiano R, Broggi G
Cancers 2023 Feb 2;15(3)
Cancers 2023 Feb 2;15(3)
Repair of airway epithelia requires metabolic rewiring towards fatty acid oxidation.
Crotta S, Villa M, Major J, Finsterbusch K, Llorian M, Carmeliet P, Buescher J, Wack A
Nature communications 2023 Feb 13;14(1):721
Nature communications 2023 Feb 13;14(1):721
SIRT3 promotes metabolic maturation of human iPSC-derived cardiomyocytes via OPA1-controlled mitochondrial dynamics.
Wang R, Xu H, Tan B, Yi Q, Sun Y, Xiang H, Chen T, Liu H, Xie Q, Wang L, Tian J, Zhu J
Free radical biology & medicine 2023 Feb 1;195:270-282
Free radical biology & medicine 2023 Feb 1;195:270-282
STAT6 promoting oxalate crystal deposition-induced renal fibrosis by mediating macrophage-to-myofibroblast transition via inhibiting fatty acid oxidation.
Yuan T, Xia Y, Pan S, Li B, Ye Z, Yan X, Hu W, Li L, Song B, Yu W, Li H, Rao T, Lin F, Zhou X, Cheng F
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2023 Dec;72(12):2111-2126
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2023 Dec;72(12):2111-2126
Exploratory metabolomic analysis based on UHPLC-Q-TOF-MS/MS to study hypoxia-reoxygenation energy metabolic alterations in HK-2 cells.
Yang X, Kang A, Lu Y, Li Y, Guo L, Li R, Zhou X
Renal failure 2023 Dec;45(1):2186715
Renal failure 2023 Dec;45(1):2186715
Mitochondrial dysfunction and endoplasmic reticulum stress induced by activation of PPARα leaded testicular to apoptosis in SD rats explored to di-(2-ethylhexyl) phthalate (DEHP).
Zhang H, Ran M, Jiang L, Sun X, Qiu T, Li J, Wang N, Yao X, Zhang C, Deng H, Wang S, Yang G
Ecotoxicology and environmental safety 2023 Dec;268:115711
Ecotoxicology and environmental safety 2023 Dec;268:115711
Stimulator of interferon genes promotes diabetic sarcopenia by targeting peroxisome proliferator activated receptors γ degradation and inhibiting fatty acid oxidation.
Yan SB, Liang H, Zhan P, Zheng H, Zhao QX, Zheng ZJ, Lu HX, Shang GK, Ji XP
Journal of cachexia, sarcopenia and muscle 2023 Dec;14(6):2623-2641
Journal of cachexia, sarcopenia and muscle 2023 Dec;14(6):2623-2641
Berberine ameliorates renal interstitial inflammation and fibrosis in mice with unilateral ureteral obstruction.
Tan E, Gao Z, Wang Q, Han B, Shi H, Wang L, Zhu G, Hou Y
Basic & clinical pharmacology & toxicology 2023 Dec;133(6):757-769
Basic & clinical pharmacology & toxicology 2023 Dec;133(6):757-769
m6A-Modified circTET2 Interacting with HNRNPC Regulates Fatty Acid Oxidation to Promote the Proliferation of Chronic Lymphocytic Leukemia.
Wu Z, Zuo X, Zhang W, Li Y, Gui R, Leng J, Shen H, Pan B, Fan L, Li J, Jin H
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Dec;10(34):e2304895
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Dec;10(34):e2304895
Aberrant centrosome biogenesis disrupts nephron and collecting duct progenitor growth and fate resulting in fibrocystic kidney disease.
Cheng T, Agwu C, Shim K, Wang B, Jain S, Mahjoub MR
Development (Cambridge, England) 2023 Dec 15;150(24)
Development (Cambridge, England) 2023 Dec 15;150(24)
α-Lactalbumin Peptide Asp-Gln-Trp Ameliorates Hepatic Steatosis and Oxidative Stress in Free Fatty Acids-Treated HepG2 Cells and High-Fat Diet-Induced NAFLD Mice by Activating the PPARα Pathway.
Chen H, Ma Y, Qi X, Tian J, Ma Y, Niu T
Molecular nutrition & food research 2023 Aug;67(16):e2200499
Molecular nutrition & food research 2023 Aug;67(16):e2200499
SIRT6 regulates obesity-induced oxidative stress via ENDOG/SOD2 signaling in the heart.
Gao S, Yang Q, Peng Y, Kong W, Liu Z, Li Z, Chen J, Bao M, Li X, Zhang Y, Bian X, Jin L, Zhang H, Zhang Y, Sanchis D, Yan F, Ye J
Cell biology and toxicology 2023 Aug;39(4):1489-1507
Cell biology and toxicology 2023 Aug;39(4):1489-1507
Novel treatment and insight for irradiation-induced injuries: Dibucaine ameliorates irradiation-induced testicular injury by inhibiting fatty acid oxidation in primary Leydig cells.
Ran L, Chen Q, Lu X, Gao Z, Cui F, Liu X, Xue B
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Aug;164:114903
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Aug;164:114903
Melatonin alleviates cadmium-induced nonalcoholic fatty liver disease in ducks by alleviating autophagic flow arrest via PPAR-α and reducing oxidative stress.
Sun J, Bian Y, Ma Y, Ali W, Wang T, Yuan Y, Gu J, Bian J, Liu Z, Zou H
Poultry science 2023 Aug;102(8):102835
Poultry science 2023 Aug;102(8):102835
Inhibition of pyruvate carboxylase reverses metformin resistance by activating AMPK in pancreatic cancer.
Liu C, Zhou X, Ju H, Zhang Y
Life sciences 2023 Aug 15;327:121817
Life sciences 2023 Aug 15;327:121817
Cordycepin reprogramming lipid metabolism to block metastasis and EMT via ERO1A/mTOR/SREBP1 axis in cholangiocarcinoma.
Zhou X, Li Y, Yang C, Chen D, Wang T, Liu T, Yan W, Su Z, Peng B, Ren X
Life sciences 2023 Aug 15;327:121698
Life sciences 2023 Aug 15;327:121698
Inhibition of Fatty Acid β-Oxidation by Fatty Acid Binding Protein 4 Induces Ferroptosis in HK2 Cells Under High Glucose Conditions.
Chen J, Wu K, Lei Y, Huang M, Cheng L, Guan H, Lin J, Zhong M, Wang X, Zheng Z
Endocrinology and metabolism (Seoul, Korea) 2023 Apr;38(2):226-244
Endocrinology and metabolism (Seoul, Korea) 2023 Apr;38(2):226-244
Protopanaxadiol ameliorates NAFLD by regulating hepatocyte lipid metabolism through AMPK/SIRT1 signaling pathway.
Li Y, Liu Y, Chen Z, Tang K, Yang L, Jiang Y, Wang J, Huang P, Wang J, Zheng P, Song H
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Apr;160:114319
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Apr;160:114319
Saturated fatty acids increase LPI to reduce FUNDC1 dimerization and stability and mitochondrial function.
Chen L, Zhang Q, Meng Y, Zhao T, Mu C, Fu C, Deng C, Feng J, Du S, Liu W, Geng G, Ma K, Cheng H, Liu Q, Luo Q, Zhang J, Du Z, Cao L, Wang H, Liu Y, Lin J, Chen G, Liu L, Lam SM, Shui G, Zhu Y, Chen Q
EMBO reports 2023 Apr 5;24(4):e54731
EMBO reports 2023 Apr 5;24(4):e54731
RASAL2 Deficiency Attenuates Hepatic Steatosis by Promoting Hepatic VLDL Secretion via the AKT/TET1/MTTP Axis.
Ding H, Yu JH, Ge G, Ma YY, Wang JC, Zhang J, Liu J
Journal of clinical and translational hepatology 2023 Apr 28;11(2):261-272
Journal of clinical and translational hepatology 2023 Apr 28;11(2):261-272
Distinct Transcriptional Responses of Skeletal Muscle to Short-Term Cold Exposure in Tibetan Pigs and Bama Pigs.
Yang C, Cao C, Liu J, Zhao Y, Pan J, Tao C, Wang Y
International journal of molecular sciences 2023 Apr 18;24(8)
International journal of molecular sciences 2023 Apr 18;24(8)
G-protein coupled receptor 19 (GPR19) knockout mice display sex-dependent metabolic dysfunction.
Mushala BAS, Xie B, Sipula IJ, Stoner MW, Thapa D, Manning JR, Bugga P, Vandevender AM, Jurczak MJ, Scott I
Scientific reports 2023 Apr 15;13(1):6134
Scientific reports 2023 Apr 15;13(1):6134
Aged green tea reduces high-fat diet-induced fat accumulation and inflammation via activating the AMP-activated protein kinase signaling pathway.
Chen R, Lai X, Xiang L, Li Q, Sun L, Lai Z, Li Z, Zhang W, Wen S, Cao J, Sun S
Food & nutrition research 2022;66
Food & nutrition research 2022;66
The Adaptive Characteristics of Cholesterol and Bile Acid Metabolism in Nile Tilapia Fed a High-Fat Diet.
Li RX, Qian YF, Zhou WH, Wang JX, Zhang YY, Luo Y, Qiao F, Chen LQ, Zhang ML, Du ZY
Aquaculture nutrition 2022;2022:8016616
Aquaculture nutrition 2022;2022:8016616
Disturbance of Fatty Acid Metabolism Promoted Vascular Endothelial Cell Senescence via Acetyl-CoA-Induced Protein Acetylation Modification.
Lin T, Yang WQ, Luo WW, Zhang LL, Mai YQ, Li ZQ, Liu ST, Jiang LJ, Liu PQ, Li ZM
Oxidative medicine and cellular longevity 2022;2022:1198607
Oxidative medicine and cellular longevity 2022;2022:1198607
The GR-gp78 Pathway is involved in Hepatic Lipid Accumulation Induced by Overexpression of 11β-HSD1.
Hu M, Han T, Pan Q, Ni D, Gao F, Wang L, Ren H, Zhang X, Jiao H, Wang Y, Dai D, Man Y, Tang W, Sun Y, Li W, Li J, Li G
International journal of biological sciences 2022;18(8):3107-3121
International journal of biological sciences 2022;18(8):3107-3121
Atractylenolide III ameliorates Non-Alcoholic Fatty Liver Disease by activating Hepatic Adiponectin Receptor 1-Mediated AMPK Pathway.
Li Q, Tan JX, He Y, Bai F, Li SW, Hou YW, Ji LS, Gao YT, Zhang X, Zhou ZH, Yu Z, Fang M, Gao YQ, Li M
International journal of biological sciences 2022;18(4):1594-1611
International journal of biological sciences 2022;18(4):1594-1611
Liver-specific overexpression of lipoprotein lipase improves glucose metabolism in high-fat diet-fed mice.
Shimizu K, Nishimuta S, Fukumura Y, Michinaga S, Egusa Y, Hase T, Terada T, Sakurai F, Mizuguchi H, Tomita K, Nishinaka T
PloS one 2022;17(9):e0274297
PloS one 2022;17(9):e0274297
Canagliflozin Attenuates Hepatic Steatosis and Atherosclerosis Progression in Western Diet-Fed ApoE-Knockout Mice.
Zuo Q, Zhang G, He L, Ma S, Ma H, Zhai J, Wang Z, Zhang T, Wang Y, Guo Y
Drug design, development and therapy 2022;16:4161-4177
Drug design, development and therapy 2022;16:4161-4177
The effects of gut microbiota colonizing on the porcine hypothalamus revealed by whole transcriptome analysis.
Qi R, Wang J, Sun J, Qiu X, Liu X, Wang Q, Yang F, Ge L, Liu Z
Frontiers in microbiology 2022;13:970470
Frontiers in microbiology 2022;13:970470
D-Mannose Regulates Hepatocyte Lipid Metabolism via PI3K/Akt/mTOR Signaling Pathway and Ameliorates Hepatic Steatosis in Alcoholic Liver Disease.
Hu M, Chen Y, Deng F, Chang B, Luo J, Dong L, Lu X, Zhang Y, Chen Z, Zhou J
Frontiers in immunology 2022;13:877650
Frontiers in immunology 2022;13:877650
Sleeve Gastrectomy-Induced AMPK Activation Attenuates Diabetic Cardiomyopathy by Maintaining Mitochondrial Homeostasis via NR4A1 Suppression in Rats.
Li S, Dong S, Xu Q, Shi B, Li L, Zhang W, Zhu J, Cheng Y, Zhang G, Zhong M
Frontiers in physiology 2022;13:837798
Frontiers in physiology 2022;13:837798
Atorvastatin Restores PPARα Inhibition of Lipid Metabolism Disorders by Downregulating miR-21 Expression to Improve Mitochondrial Function and Alleviate Diabetic Nephropathy Progression.
Xiang J, Zhang H, Zhou X, Wang D, Chen R, Tan W, Liang L, Shi M, Zhang F, Xiao Y, Zhou Y, Wang Y, Guo B
Frontiers in pharmacology 2022;13:819787
Frontiers in pharmacology 2022;13:819787
Imbalance hepatic metabolism homeostasis in the F1 generation of endometrial DNMT3B conditional knockout female mice.
Li W, Gao R, Ding Y, Chen X, Liu X, He J, Li F, Long J, Lu S, Yang C, Wang Y
Frontiers in physiology 2022;13:1042449
Frontiers in physiology 2022;13:1042449
Mitochondrial STAT3 exacerbates LPS-induced sepsis by driving CPT1a-mediated fatty acid oxidation.
Li R, Li X, Zhao J, Meng F, Yao C, Bao E, Sun N, Chen X, Cheng W, Hua H, Li X, Wang B, Wang H, Pan X, You H, Yang J, Ikezoe T
Theranostics 2022;12(2):976-998
Theranostics 2022;12(2):976-998
CD147 Mediates 5-Fluorouracil Resistance in Colorectal Cancer by Reprogramming Glycolipid Metabolism.
Dong S, Li S, Wang X, Liang S, Zhang W, Li L, Xu Q, Shi B, Cheng Z, Zhang X, Zhong M, Zhang G, Hu S
Frontiers in oncology 2022;12:813852
Frontiers in oncology 2022;12:813852
PTPRO represses colorectal cancer tumorigenesis and progression by reprogramming fatty acid metabolism.
Dai W, Xiang W, Han L, Yuan Z, Wang R, Ma Y, Yang Y, Cai S, Xu Y, Mo S, Li Q, Cai G
Cancer communications (London, England) 2022 Sep;42(9):848-867
Cancer communications (London, England) 2022 Sep;42(9):848-867
Metabolic Syndrome Ameliorated by 4-Methylesculetin by Reducing Hepatic Lipid Accumulation.
Li L, Zhu G, Fu G, Zha W, Li H
International journal of molecular sciences 2022 Sep 9;23(18)
International journal of molecular sciences 2022 Sep 9;23(18)
Transcriptomic responses are sex-dependent in the skeletal muscle and liver in offspring of obese mice.
Kelly AC, J Rosario F, Chan J, Cox LA, Powell TL, Jansson T
American journal of physiology. Endocrinology and metabolism 2022 Oct 1;323(4):E336-E353
American journal of physiology. Endocrinology and metabolism 2022 Oct 1;323(4):E336-E353
The HSF1-CPT1a Pathway Is Differentially Regulated in NAFLD Progression.
Breternitz W, Sandkühler F, Grohmann F, Hampe J, Brosch M, Herrmann A, Schafmayer C, Meinhardt C, Schreiber S, Arlt A, Geismann C
Cells 2022 Nov 4;11(21)
Cells 2022 Nov 4;11(21)
WY-14643 attenuates lipid deposition via activation of the PPARα/CPT1A axis by targeting Gly335 to inhibit cell proliferation and migration in ccRCC.
Wang R, Zhao J, Jin J, Tian Y, Lan L, Wang X, Zhu L, Wang J
Lipids in health and disease 2022 Nov 16;21(1):121
Lipids in health and disease 2022 Nov 16;21(1):121
Maternal high-fructose corn syrup consumption causes insulin resistance and hyperlipidemia in offspring via DNA methylation of the Pparα promoter region.
Ando Y, Yamada H, Munetsuna E, Yamazaki M, Kageyama I, Teshigawara A, Nouchi Y, Fujii R, Mizuno G, Sadamoto N, Ishikawa H, Suzuki K, Hashimoto S, Ohashi K
The Journal of nutritional biochemistry 2022 May;103:108951
The Journal of nutritional biochemistry 2022 May;103:108951
Piperine Improves Lipid Dysregulation by Modulating Circadian Genes Bmal1 and Clock in HepG2 Cells.
Zhang W, Ho CT, Lu M
International journal of molecular sciences 2022 May 17;23(10)
International journal of molecular sciences 2022 May 17;23(10)
SIRT1 prevents cigarette smoking-induced lung fibroblasts activation by regulating mitochondrial oxidative stress and lipid metabolism.
Zhang Y, Li T, Pan M, Wang W, Huang W, Yuan Y, Xie Z, Chen Y, Peng J, Li X, Meng Y
Journal of translational medicine 2022 May 14;20(1):222
Journal of translational medicine 2022 May 14;20(1):222
The Ameliorating Effects of Apple Polyphenol Extract on High-Fat-Diet-Induced Hepatic Steatosis Are SIRT1-Dependent: Evidence from Hepatic-Specific SIRT1 Heterozygous Mutant C57BL/6 Mice.
Yin Y, Li D, Liu F, Wang X, Cui Y, Li S, Li X
Journal of agricultural and food chemistry 2022 May 11;70(18):5579-5594
Journal of agricultural and food chemistry 2022 May 11;70(18):5579-5594
A roadmap for the characterization of energy metabolism in human cardiomyocytes derived from induced pluripotent stem cells.
Emanuelli G, Zoccarato A, Reumiller CM, Papadopoulos A, Chong M, Rebs S, Betteridge K, Beretta M, Streckfuss-Bömeke K, Shah AM
Journal of molecular and cellular cardiology 2022 Mar;164:136-147
Journal of molecular and cellular cardiology 2022 Mar;164:136-147
In vitro absorption and lipid-lowering activity of baicalin esters synthesized by whole-cell catalyzed esterification.
Zhang M, Xin X, Zhao G, Zou Y, Li XF
Bioorganic chemistry 2022 Mar;120:105628
Bioorganic chemistry 2022 Mar;120:105628
Highland barley Monascus purpureus Went extract ameliorates high-fat, high-fructose, high-cholesterol diet induced nonalcoholic fatty liver disease by regulating lipid metabolism in golden hamsters.
Zhao CZ, Jiang W, Zhu YY, Wang CZ, Zhong WH, Wu G, Chen J, Zhu MN, Wu QL, Du XL, Luo YY, Li M, Wang HL, Zhao H, Ma QG, Zhong GY, Wei RR
Journal of ethnopharmacology 2022 Mar 25;286:114922
Journal of ethnopharmacology 2022 Mar 25;286:114922
Psoralen Suppresses Lipid Deposition by Alleviating Insulin Resistance and Promoting Autophagy in Oleate-Induced L02 Cells.
Wang Y, Wang Y, Li F, Zou J, Li X, Xu M, Yu D, Ma Y, Huang W, Sun X, Zhang Y
Cells 2022 Mar 22;11(7)
Cells 2022 Mar 22;11(7)
Short-term intermittent cigarette smoke exposure enhances alveolar type 2 cell stemness via fatty acid oxidation.
Irie H, Ozaki M, Chubachi S, Hegab AE, Tsutsumi A, Kameyama N, Sakurai K, Nakayama S, Kagawa S, Wada S, Ishii M, Betsuyaku T, Fukunaga K
Respiratory research 2022 Mar 2;23(1):41
Respiratory research 2022 Mar 2;23(1):41
Increased fatty acid metabolism attenuates cardiac resistance to β-adrenoceptor activation via mitochondrial reactive oxygen species: A potential mechanism of hypoglycemia-induced myocardial injury in diabetes.
Huang L, Chen Z, Chen R, Lin L, Ren L, Zhang M, Liu L
Redox biology 2022 Jun;52:102320
Redox biology 2022 Jun;52:102320
Inhibition of Fatty Acid Translocase (FAT/CD36) Palmitoylation Enhances Hepatic Fatty Acid β-Oxidation by Increasing Its Localization to Mitochondria and Interaction with Long-Chain Acyl-CoA Synthetase 1.
Zeng S, Wu F, Chen M, Li Y, You M, Zhang Y, Yang P, Wei L, Ruan XZ, Zhao L, Chen Y
Antioxidants & redox signaling 2022 Jun;36(16-18):1081-1100
Antioxidants & redox signaling 2022 Jun;36(16-18):1081-1100
Diallyl disulfide ameliorates ethanol-induced liver steatosis and inflammation by maintaining the fatty acid catabolism and regulating the gut-liver axis.
Liu SX, Liu H, Wang S, Zhang CL, Guo FF, Zeng T
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2022 Jun;164:113108
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2022 Jun;164:113108
Transcriptome Comparison Reveals the Difference in Liver Fat Metabolism between Different Sheep Breeds.
Li T, Jin M, Fei X, Yuan Z, Wang Y, Quan K, Wang T, Yang J, He M, Wei C
Animals : an open access journal from MDPI 2022 Jun 27;12(13)
Animals : an open access journal from MDPI 2022 Jun 27;12(13)
PP1A prevents ROS-induced pyroptosis by inhibiting MAPK/caspase-3 in mouse adipose tissue.
Chen Y, Che M, Li C, Li Y, Zhang T, Li X, Sun C
The FEBS journal 2022 Jul;289(13):3839-3853
The FEBS journal 2022 Jul;289(13):3839-3853
Exercise promotes angiogenesis by enhancing endothelial cell fatty acid utilization via liver-derived extracellular vesicle miR-122-5p.
Lou J, Wu J, Feng M, Dang X, Wu G, Yang H, Wang Y, Li J, Zhao Y, Shi C, Liu J, Zhao L, Zhang X, Gao F
Journal of sport and health science 2022 Jul;11(4):495-508
Journal of sport and health science 2022 Jul;11(4):495-508
Overexpression of carnitine palmitoyltransferase 1A promotes mitochondrial fusion and differentiation of glioblastoma stem cells.
Luo M, Liu YQ, Zhang H, Luo CH, Liu Q, Wang WY, He ZC, Chen C, Zhang XN, Mao M, Yang KD, Wang C, Chen XQ, Fu WJ, Niu Q, Bian XW, Shi Y, Ping YF
Laboratory investigation; a journal of technical methods and pathology 2022 Jul;102(7):722-730
Laboratory investigation; a journal of technical methods and pathology 2022 Jul;102(7):722-730
Endurance exercise-mediated metabolic reshuffle attenuates high-caloric diet-induced non-alcoholic fatty liver disease.
Cook JJ, Wei M, Segovia B, Cosio-Lima L, Simpson J, Taylor S, Koh Y, Kim S, Lee Y
Annals of hepatology 2022 Jul-Aug;27(4):100709
Annals of hepatology 2022 Jul-Aug;27(4):100709
Lactoferrin Prevents Chronic Alcoholic Injury by Regulating Redox Balance and Lipid Metabolism in Female C57BL/6J Mice.
Li DM, Wu YX, Hu ZQ, Wang TC, Zhang LL, Zhou Y, Tong X, Xu JY, Qin LQ
Antioxidants (Basel, Switzerland) 2022 Jul 31;11(8)
Antioxidants (Basel, Switzerland) 2022 Jul 31;11(8)
Nutritional programming of large yellow croaker (Larimichthys crocea) larvae by dietary vegetable oil: effects on growth performance, lipid metabolism and antioxidant capacity.
Liu Y, Yao C, Cui K, Hao T, Yin Z, Xu W, Huang W, Mai K, Ai Q
The British journal of nutrition 2022 Jul 11;:1-14
The British journal of nutrition 2022 Jul 11;:1-14
Constituents of Morus alba var. multicaulis leaf improve lipid metabolism by activating the AMPK signaling pathway in HepG2 cells.
Huang P, Hao M, Gao Q, Ruan J, Yang S, Liu M, Chen Q, Zhang Y, Wang T
Journal of natural medicines 2022 Jan;76(1):200-209
Journal of natural medicines 2022 Jan;76(1):200-209
Chronic angiotensin receptor activation promotes hepatic triacylglycerol accumulation during an acute glucose challenge in obese-insulin-resistant OLETF rats.
Godoy-Lugo JA, Thorwald MA, Hui DY, Nishiyama A, Nakano D, Soñanez-Organis JG, Ortiz RM
Endocrine 2022 Jan;75(1):92-107
Endocrine 2022 Jan;75(1):92-107
Targeting Cpt1a-Bcl-2 interaction modulates apoptosis resistance and fibrotic remodeling.
Gu L, Surolia R, Larson-Casey JL, He C, Davis D, Kang J, Antony VB, Carter AB
Cell death and differentiation 2022 Jan;29(1):118-132
Cell death and differentiation 2022 Jan;29(1):118-132
Enhancement of Acylcarnitine Levels in Small Intestine of Abdominal Irradiation Rats Might Relate to Fatty Acid β-Oxidation Pathway Disequilibration.
Liu HX, Lu X, Zhao H, Li S, Gao L, Tian M, Liu QJ
Dose-response : a publication of International Hormesis Society 2022 Jan-Mar;20(1):15593258221075118
Dose-response : a publication of International Hormesis Society 2022 Jan-Mar;20(1):15593258221075118
Gestational bisphenol A exposure impairs hepatic lipid metabolism by altering mTOR/CRTC2/SREBP1 in male rat offspring.
Yang Q, Mao Y, Wang J, Yu H, Zhang X, Pei X, Duan Z, Xiao C, Ma M
Human & experimental toxicology 2022 Jan-Dec;41:9603271221129852
Human & experimental toxicology 2022 Jan-Dec;41:9603271221129852
Steatosis induced by nonylphenol in HepG2 cells and the intervention effect of curcumin.
Shan D, Wang J, Di Q, Jiang Q, Xu Q
Food & function 2022 Jan 4;13(1):327-343
Food & function 2022 Jan 4;13(1):327-343
Dopamine receptor D1 signaling stimulates lipolysis and browning of white adipocytes.
Yu J, Zhu J, Deng J, Shen J, Du F, Wu X, Chen Y, Li M, Wen Q, Xiao Z, Zhao Y
Biochemical and biophysical research communications 2022 Jan 15;588:83-89
Biochemical and biophysical research communications 2022 Jan 15;588:83-89
Isoliquiritigenin-mediated miR-23a-3p inhibition activates PGC-1α to alleviate alcoholic liver injury.
Wang L, Kong L, Xu S, Wang X, Huang K, Wang S, Wu J, Wang C, Sun H, Liu K, Meng Q
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Feb;96:153845
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Feb;96:153845
Mildronate triggers growth suppression and lipid accumulation in largemouth bass (Micropterus salmoides) through disturbing lipid metabolism.
Wang JX, Rahimnejad S, Zhang YY, Ren J, Wang J, Qiao F, Zhang ML, Du ZY
Fish physiology and biochemistry 2022 Feb;48(1):145-159
Fish physiology and biochemistry 2022 Feb;48(1):145-159
Activation of PGC-1α via isoliquiritigenin-induced downregulation of miR-138-5p alleviates nonalcoholic fatty liver disease.
Wang L, Wang X, Kong L, Li Y, Huang K, Wu J, Wang C, Sun H, Sun P, Gu J, Luo H, Liu K, Meng Q
Phytotherapy research : PTR 2022 Feb;36(2):899-913
Phytotherapy research : PTR 2022 Feb;36(2):899-913
Ginsenoside CK ameliorates hepatic lipid accumulation via activating the LKB1/AMPK pathway in vitro and in vivo.
Zhang J, Ma X, Fan D
Food & function 2022 Feb 7;13(3):1153-1167
Food & function 2022 Feb 7;13(3):1153-1167
FUS Mutation Causes Disordered Lipid Metabolism in Skeletal Muscle Associated with ALS.
Zhou B, Zheng Y, Li X, Dong H, Yu J, Zou Y, Zhu M, Yu Y, Fang X, Zhou M, Zhang W, Yuan Y, Wang Z, Deng J, Hong D
Molecular neurobiology 2022 Dec;59(12):7265-7277
Molecular neurobiology 2022 Dec;59(12):7265-7277
Ethanolic extract of root from Arctium lappa L ameliorates obesity and hepatic steatosis in rats by regulating the AMPK/ACC/CPT-1 pathway.
Ma K, Sheng W, Gao R, Feng J, Huang W, Cui L, Liu J, Li Y
Journal of food biochemistry 2022 Dec;46(12):e14455
Journal of food biochemistry 2022 Dec;46(12):e14455
Hif-2α regulates lipid metabolism in alcoholic fatty liver disease through mitophagy.
Wu MF, Zhang GD, Liu TT, Shen JH, Cheng JL, Shen J, Yang TY, Huang C, Zhang L
Cell & bioscience 2022 Dec 7;12(1):198
Cell & bioscience 2022 Dec 7;12(1):198
A novel small compound TOIDC suppresses lipogenesis via SREBP1-dependent signaling to curb MAFLD.
Shao Y, Yao Z, Zhou J, Yu M, Chen S, Yuan Y, Han L, Jiang L, Liu J
Nutrition & metabolism 2022 Dec 6;19(1):80
Nutrition & metabolism 2022 Dec 6;19(1):80
Neutrophil trafficking to the site of infection requires Cpt1a-dependent fatty acid β-oxidation.
Pham L, Komalavilas P, Eddie AM, Thayer TE, Greenwood DL, Liu KH, Weinberg J, Patterson A, Fessel JP, Boyd KL, Schafer JC, Kuck JL, Shaver AC, Flaherty DK, Matlock BK, Wijers CDM, Serezani CH, Jones DP, Brittain EL, Rathmell JC, Noto MJ
Communications biology 2022 Dec 13;5(1):1366
Communications biology 2022 Dec 13;5(1):1366
MPYS Modulates Fatty Acid Metabolism and Immune Tolerance at Homeostasis Independent of Type I IFNs.
Mansouri S, Gogoi H, Patel S, Katikaneni DS, Singh A, Aybar-Torres A, de Lartigue G, Jin L
Journal of immunology (Baltimore, Md. : 1950) 2022 Dec 1;209(11):2114-2132
Journal of immunology (Baltimore, Md. : 1950) 2022 Dec 1;209(11):2114-2132
Elevated thyroid hormones caused by high concentrate diets participate in hepatic metabolic disorders in dairy cows.
Chen Q, Wu C, Yao Z, Cai L, Ni Y, Mao S
Animal bioscience 2022 Aug;35(8):1184-1194
Animal bioscience 2022 Aug;35(8):1184-1194
Metabolic reprogramming from glycolysis to fatty acid uptake and beta-oxidation in platinum-resistant cancer cells.
Tan Y, Li J, Zhao G, Huang KC, Cardenas H, Wang Y, Matei D, Cheng JX
Nature communications 2022 Aug 5;13(1):4554
Nature communications 2022 Aug 5;13(1):4554
CRIP1 suppresses BBOX1-mediated carnitine metabolism to promote stemness in hepatocellular carcinoma.
Wang J, Zhou Y, Zhang D, Zhao W, Lu Y, Liu C, Lin W, Zhang Y, Chen K, Wang H, Zhao L
The EMBO journal 2022 Aug 1;41(15):e110218
The EMBO journal 2022 Aug 1;41(15):e110218
Ketogenesis acts as an endogenous protective programme to restrain inflammatory macrophage activation during acute pancreatitis.
Zhang L, Shi J, Du D, Niu N, Liu S, Yang X, Lu P, Shen X, Shi N, Yao L, Zhang R, Hu G, Lu G, Zhu Q, Zeng T, Liu T, Xia Q, Huang W, Xue J
EBioMedicine 2022 Apr;78:103959
EBioMedicine 2022 Apr;78:103959
The activation of PPARγ enhances Treg responses through up-regulating CD36/CPT1-mediated fatty acid oxidation and subsequent N-glycan branching of TβRII/IL-2Rα.
Miao Y, Zhang C, Yang L, Zeng X, Hu Y, Xue X, Dai Y, Wei Z
Cell communication and signaling : CCS 2022 Apr 7;20(1):48
Cell communication and signaling : CCS 2022 Apr 7;20(1):48
L-theanine prevents progression of nonalcoholic hepatic steatosis by regulating hepatocyte lipid metabolic pathways via the CaMKKβ-AMPK signaling pathway.
Liang J, Gu L, Liu X, Yan X, Bi X, Fan X, Zhou J, Lu S, Luo L, Yin Z
Nutrition & metabolism 2022 Apr 15;19(1):29
Nutrition & metabolism 2022 Apr 15;19(1):29
Succinylation Regulators Promote Clear Cell Renal Cell Carcinoma by Immune Regulation and RNA N6-Methyladenosine Methylation.
Lu W, Che X, Qu X, Zheng C, Yang X, Bao B, Li Z, Wang D, Jin Y, Wang Y, Xiao J, Qi J, Liu Y
Frontiers in cell and developmental biology 2021;9:622198
Frontiers in cell and developmental biology 2021;9:622198
Dendrobium officinale Regulates Fatty Acid Metabolism to Ameliorate Liver Lipid Accumulation in NAFLD Mice.
Lei SS, Zhang NY, Zhou FC, He X, Wang HY, Li LZ, Zheng X, Dong YJ, Luo R, Li B, Jin HY, Yu QX, Lv GY, Chen SH
Evidence-based complementary and alternative medicine : eCAM 2021;2021:6689727
Evidence-based complementary and alternative medicine : eCAM 2021;2021:6689727
Recombinant Human Growth Hormone Inhibits Lipotoxicity, Oxidative Stress, and Apoptosis in a Mouse Model of Diabetic Cardiomyopathy.
Pei Z, Wang X, Yang C, Dong M, Wang F
Oxidative medicine and cellular longevity 2021;2021:3899356
Oxidative medicine and cellular longevity 2021;2021:3899356
ZLN005 protects against ischemia-reperfusion-induced kidney injury by mitigating oxidative stress through the restoration of mitochondrial fatty acid oxidation.
Wang Z, Fu Z, Wang C, Xu J, Ma H, Jiang M, Xu T, Feng X, Zhang W
American journal of translational research 2021;13(9):10014-10037
American journal of translational research 2021;13(9):10014-10037
Activation of TAF9 via Danshensu-Induced Upregulation of HDAC1 Expression Alleviates Non-alcoholic Fatty Liver Disease.
Wang R, Wang Z, Sun R, Fu R, Sun Y, Zhu M, Geng Y, Gao D, Tian X, Zhao Y, Yao J
Frontiers in pharmacology 2021;12:775528
Frontiers in pharmacology 2021;12:775528
High-Salt Attenuates the Efficacy of Dapagliflozin in Tubular Protection by Impairing Fatty Acid Metabolism in Diabetic Kidney Disease.
Zou M, Chen Y, Zheng Z, Sheng S, Jia Y, Wang X, Ren S, Yang Y, Li X, Dong W, Guan M, Zhang Q, Xue Y
Frontiers in pharmacology 2021;12:741087
Frontiers in pharmacology 2021;12:741087
Endoplasmic Reticulum Stress Disturbs Lipid Homeostasis and Augments Inflammation in the Intestine and Isolated Intestinal Cells of Large Yellow Croaker (Larimichthys crocea).
Fang W, Chen Q, Li J, Liu Y, Zhao Z, Shen Y, Mai K, Ai Q
Frontiers in immunology 2021;12:738143
Frontiers in immunology 2021;12:738143
Mitofusin 2 Deficiency Causes Pro-Inflammatory Effects in Human Primary Macrophages.
Khodzhaeva V, Schreiber Y, Geisslinger G, Brandes RP, Brüne B, Namgaladze D
Frontiers in immunology 2021;12:723683
Frontiers in immunology 2021;12:723683
Antiproliferative, Antiangiogenic, and Antimetastatic Therapy Response by Mangiferin in a Syngeneic Immunocompetent Colorectal Cancer Mouse Model Involves Changes in Mitochondrial Energy Metabolism.
Rodriguez-Gonzalez JC, Hernández-Balmaseda I, Declerck K, Pérez-Novo C, Logie E, Theys C, Jakubek P, Quiñones-Maza OL, Dantas-Cassali G, Carlos Dos Reis D, Van Camp G, Lopes Paz MT, Rodeiro-Guerra I, Delgado-Hernández R, Vanden Berghe W
Frontiers in pharmacology 2021;12:670167
Frontiers in pharmacology 2021;12:670167
Lysosome-Dependent LXR and PPARδ Activation Upon Efferocytosis in Human Macrophages.
Mota AC, Dominguez M, Weigert A, Snodgrass RG, Namgaladze D, Brüne B
Frontiers in immunology 2021;12:637778
Frontiers in immunology 2021;12:637778
Effects of High Levels of Dietary Linseed Oil on the Growth Performance, Antioxidant Capacity, Hepatic Lipid Metabolism, and Expression of Inflammatory Genes in Large Yellow Croaker (Larimichthys crocea).
Li X, Chen Q, Li Q, Li J, Cui K, Zhang Y, Kong A, Zhang Y, Wan M, Mai K, Ai Q
Frontiers in physiology 2021;12:631850
Frontiers in physiology 2021;12:631850
Daily Dose of Bovine Lactoferrin Prevents Ethanol-Induced Liver Injury and Death in Male Mice by Regulating Hepatic Alcohol Metabolism and Modulating Gut Microbiota.
Li D, He Q, Yang H, Du Y, Yu K, Yang J, Tong X, Guo Y, Xu J, Qin L
Molecular nutrition & food research 2021 Sep;65(18):e2100253
Molecular nutrition & food research 2021 Sep;65(18):e2100253
Pterostilbene attenuates RIPK3-dependent hepatocyte necroptosis in alcoholic liver disease via SIRT2-mediated NFATc4 deacetylation.
Shao Y, Wang X, Zhou Y, Jiang Y, Wu R, Lu C
Toxicology 2021 Sep;461:152923
Toxicology 2021 Sep;461:152923
CPT1A and fatty acid β-oxidation are essential for tumor cell growth and survival in hormone receptor-positive breast cancer.
Jariwala N, Mehta GA, Bhatt V, Hussein S, Parker KA, Yunus N, Parker JS, Guo JY, Gatza ML
NAR cancer 2021 Sep;3(3):zcab035
NAR cancer 2021 Sep;3(3):zcab035
Live Combined B. subtilis and E. faecium Alleviate Liver Inflammation, Improve Intestinal Barrier Function, and Modulate Gut Microbiota in Mice with Non-Alcoholic Fatty Liver Disease.
Jiang J, Xiong J, Ni J, Chen C, Wang K
Medical science monitor : international medical journal of experimental and clinical research 2021 Sep 5;27:e931143
Medical science monitor : international medical journal of experimental and clinical research 2021 Sep 5;27:e931143
Exposure to ethephon compromises endometrial decidualization in mice during early pregnancy via GPR120.
Huang C, Wang D, Li N, Yang C, Chen X, Liu X, He J, Ding Y, Tong C, Peng C, Li F, Wang Y, Gao R
Ecotoxicology and environmental safety 2021 Sep 1;220:112361
Ecotoxicology and environmental safety 2021 Sep 1;220:112361
Dihydroartemisinin regulates lipid droplet metabolism in hepatic stellate cells by inhibiting lncRNA-H19-induced AMPK signal.
Xia S, Wang Z, Chen L, Zhou Y, Li Y, Wang S, Chen A, Xu X, Shao J, Zhang Z, Tan S, Zhang F, Zheng S
Biochemical pharmacology 2021 Oct;192:114730
Biochemical pharmacology 2021 Oct;192:114730
Bioactive flavonoids and stilbenes from the leaf of Morus alba var. multicaulis.
Hao M, Huang P, Ruan J, Sun F, Han L, Liu M, Zhang Y, Wang T
Fitoterapia 2021 Oct;154:105018
Fitoterapia 2021 Oct;154:105018
PGC1α-Mediated Metabolic Reprogramming Drives the Stemness of Pancreatic Precursor Lesions.
Nimmakayala RK, Rauth S, Chirravuri Venkata R, Marimuthu S, Nallasamy P, Vengoji R, Lele SM, Rachagani S, Mallya K, Malafa MP, Ponnusamy MP, Batra SK
Clinical cancer research : an official journal of the American Association for Cancer Research 2021 Oct 1;27(19):5415-5429
Clinical cancer research : an official journal of the American Association for Cancer Research 2021 Oct 1;27(19):5415-5429
Sex-specific genetic regulation of adipose mitochondria and metabolic syndrome by Ndufv2.
Chella Krishnan K, Vergnes L, Acín-Pérez R, Stiles L, Shum M, Ma L, Mouisel E, Pan C, Moore TM, Péterfy M, Romanoski CE, Reue K, Björkegren JLM, Laakso M, Liesa M, Lusis AJ
Nature metabolism 2021 Nov;3(11):1552-1568
Nature metabolism 2021 Nov;3(11):1552-1568
The modified mitochondrial outer membrane carrier MTCH2 links mitochondrial fusion to lipogenesis.
Labbé K, Mookerjee S, Le Vasseur M, Gibbs E, Lerner C, Nunnari J
The Journal of cell biology 2021 Nov 1;220(11)
The Journal of cell biology 2021 Nov 1;220(11)
High-fat diet-induced obesity primes fatty acid β-oxidation impairment and consequent ovarian dysfunction during early pregnancy.
Li Q, Guo S, Yang C, Liu X, Chen X, He J, Tong C, Ding Y, Peng C, Geng Y, Mu X, Liu T, Li F, Wang Y, Gao R
Annals of translational medicine 2021 May;9(10):887
Annals of translational medicine 2021 May;9(10):887
Danthron ameliorates obesity and MAFLD through activating the interplay between PPARα/RXRα heterodimer and adiponectin receptor 2.
Ma C, Wang Z, Xia R, Wei L, Zhang C, Zhang J, Zhao L, Wu H, Kang L, Yang S
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 May;137:111344
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 May;137:111344
Simultaneously targeting SOAT1 and CPT1A ameliorates hepatocellular carcinoma by disrupting lipid homeostasis.
Ren M, Xu H, Xia H, Tang Q, Bi F
Cell death discovery 2021 May 29;7(1):125
Cell death discovery 2021 May 29;7(1):125
Apple polyphenol extract alleviates lipid accumulation in free-fatty-acid-exposed HepG2 cells via activating autophagy mediated by SIRT1/AMPK signaling.
Li D, Cui Y, Wang X, Liu F, Li X
Phytotherapy research : PTR 2021 Mar;35(3):1416-1431
Phytotherapy research : PTR 2021 Mar;35(3):1416-1431
Glioma cells survival depends both on fatty acid oxidation and on functional carnitine transport by SLC22A5.
Juraszek B, Czarnecka-Herok J, Nałęcz KA
Journal of neurochemistry 2021 Mar;156(5):642-657
Journal of neurochemistry 2021 Mar;156(5):642-657
FGF1(ΔHBS) prevents diabetic cardiomyopathy by maintaining mitochondrial homeostasis and reducing oxidative stress via AMPK/Nur77 suppression.
Wang D, Yin Y, Wang S, Zhao T, Gong F, Zhao Y, Wang B, Huang Y, Cheng Z, Zhu G, Wang Z, Wang Y, Ren J, Liang G, Li X, Huang Z
Signal transduction and targeted therapy 2021 Mar 24;6(1):133
Signal transduction and targeted therapy 2021 Mar 24;6(1):133
Effect of selenium-enriched kiwifruit on body fat reduction and liver protection in hyperlipidaemic mice.
Zhang X, Xia H, Wang J, Leng R, Zhou X, Gao Q, He K, Liu D, Huang B
Food & function 2021 Mar 15;12(5):2044-2057
Food & function 2021 Mar 15;12(5):2044-2057
Icaritin ameliorates hepatic steatosis via promoting fatty acid β-oxidation and insulin sensitivity.
Xiong Y, Chen Y, Huang X, Yang Z, Zhang J, Yu X, Fang J, Tao J, You K, Cheng Z, Tan S, Xu Y, Yuan F, Liu Y, Zhuang Y, Yang F, Li Y
Life sciences 2021 Mar 1;268:119000
Life sciences 2021 Mar 1;268:119000
Marein ameliorates Ang II/hypoxia-induced abnormal glucolipid metabolism by modulating the HIF-1α/PPARα/γ pathway in H9c2 cells.
Niu G, Zhou M, Wang F, Yang J, Huang J, Zhu Z
Drug development research 2021 Jun;82(4):523-532
Drug development research 2021 Jun;82(4):523-532
Deficiency of Mitochondrial Glycerol 3-Phosphate Dehydrogenase Exacerbates Podocyte Injury and the Progression of Diabetic Kidney Disease.
Qu H, Gong X, Liu X, Zhang R, Wang Y, Huang B, Zhang L, Zheng H, Zheng Y
Diabetes 2021 Jun;70(6):1372-1387
Diabetes 2021 Jun;70(6):1372-1387
Carbohydrate response element-binding protein regulates lipid metabolism via mTOR complex1 in diabetic nephropathy.
Chen N, Mu L, Yang Z, Du C, Wu M, Song S, Yuan C, Shi Y
Journal of cellular physiology 2021 Jan;236(1):625-640
Journal of cellular physiology 2021 Jan;236(1):625-640
Skip participates in formation and lipid metabolism of beige adipose and might mediate the effects of SIRT1 activator BTM-0512 on beige remodeling.
Liao ZM, Li AN, Cai Y, Chen JJ, Xu Y, Sui LH, Wang JL, Jin P, Wang KS, Yang ZC
Biochemical and biophysical research communications 2021 Jan 22;537:109-117
Biochemical and biophysical research communications 2021 Jan 22;537:109-117
Proteomic Analysis Reveals the Effect of Trichostatin A and Bone Marrow-Derived Dendritic Cells on the Fatty Acid Metabolism of NIH3T3 Cells under Oxygen-Glucose Deprivation Conditions.
Wang X, Song T, Sun Y, Men L, Gu Y, Zhang S, Chen X
Journal of proteome research 2021 Jan 1;20(1):960-971
Journal of proteome research 2021 Jan 1;20(1):960-971
Cordycepin attenuates high-fat diet-induced non-alcoholic fatty liver disease via down-regulation of lipid metabolism and inflammatory responses.
Gong X, Li T, Wan R, Sha L
International immunopharmacology 2021 Feb;91:107173
International immunopharmacology 2021 Feb;91:107173
Single Mutation in the NFU1 Gene Metabolically Reprograms Pulmonary Artery Smooth Muscle Cells.
James J, Zemskova M, Eccles CA, Varghese MV, Niihori M, Barker NK, Luo M, Mandarino LJ, Langlais PR, Rafikova O, Rafikov R
Arteriosclerosis, thrombosis, and vascular biology 2021 Feb;41(2):734-754
Arteriosclerosis, thrombosis, and vascular biology 2021 Feb;41(2):734-754
Roles of acyl-CoA synthetase long-chain family member 5 and colony stimulating factor 2 in inhibition of palmitic or stearic acids in lung cancer cell proliferation and metabolism.
Zhang L, Lv J, Chen C, Wang X
Cell biology and toxicology 2021 Feb;37(1):15-34
Cell biology and toxicology 2021 Feb;37(1):15-34
HRD1 inhibits fatty acid oxidation and tumorigenesis by ubiquitinating CPT2 in triple-negative breast cancer.
Guo X, Wang A, Wang W, Wang Y, Chen H, Liu X, Xia T, Zhang A, Chen D, Qi H, Ling T, Piao HL, Wang HJ
Molecular oncology 2021 Feb;15(2):642-656
Molecular oncology 2021 Feb;15(2):642-656
Gentisic acid prevents diet-induced obesity in mice by accelerating the thermogenesis of brown adipose tissue.
Han X, Guo J, Gao Y, Zhan J, You Y, Huang W
Food & function 2021 Feb 15;12(3):1262-1270
Food & function 2021 Feb 15;12(3):1262-1270
18β-glycyrrhetinic acid improves high-intensity exercise performance by promoting glucose-dependent energy production and inhibiting oxidative stress in mice.
Ma X, Chen H, Cao L, Zhao S, Zhao C, Yin S, Hu H
Phytotherapy research : PTR 2021 Dec;35(12):6932-6943
Phytotherapy research : PTR 2021 Dec;35(12):6932-6943
NMR-based untargeted metabolomics approach to investigate the systemic lipid metabolism regulation of norisoboldine in collagen-induced arthritis rats.
Fang Y, Duan C, Zhang J, Dai Y, Xia Y
European journal of pharmacology 2021 Dec 5;912:174608
European journal of pharmacology 2021 Dec 5;912:174608
Carnitine Palmitoyltransferase 1 Regulates Prostate Cancer Growth under Hypoxia.
Rios-Colon L, Kumar P, Kim S, Sharma M, Su Y, Kumar A, Singh S, Stocks N, Liu L, Joshi M, Schlaepfer IR, Kumar D, Deep G
Cancers 2021 Dec 15;13(24)
Cancers 2021 Dec 15;13(24)
FXR, a Key Regulator of Lipid Metabolism, Is Inhibited by ER Stress-Mediated Activation of JNK and p38 MAPK in Large Yellow Croakers (Larimichthys crocea) Fed High Fat Diets.
Du J, Xiang X, Xu D, Zhang J, Fang W, Xu W, Mai K, Ai Q
Nutrients 2021 Dec 1;13(12)
Nutrients 2021 Dec 1;13(12)
GEO data mining and TCGA analysis reveal altered branched chain amino acid metabolism in pancreatic cancer patients.
Li JY, Sun F, Yang CL, Zhou HF, Gao M, Zhang Q, Chen H, Zhou P, Xiao J, Fan H
Aging 2021 Apr 21;13(8):11907-11918
Aging 2021 Apr 21;13(8):11907-11918
Echinacoside improves diabetic liver injury by regulating the AMPK/SIRT1 signaling pathway in db/db mice.
Yang L, Zhang X, Liao M, Hao Y
Life sciences 2021 Apr 15;271:119237
Life sciences 2021 Apr 15;271:119237
The Role of GPR109a Signaling in Niacin Induced Effects on Fed and Fasted Hepatic Metabolism.
Geisler CE, Miller KE, Ghimire S, Renquist BJ
International journal of molecular sciences 2021 Apr 13;22(8)
International journal of molecular sciences 2021 Apr 13;22(8)
Tributyrin Inhibits Ethanol-Induced Epigenetic Repression of CPT-1A and Attenuates Hepatic Steatosis and Injury.
Donde H, Ghare S, Joshi-Barve S, Zhang J, Vadhanam MV, Gobejishvili L, Lorkiewicz P, Srivastava S, McClain CJ, Barve S
Cellular and molecular gastroenterology and hepatology 2020;9(4):569-585
Cellular and molecular gastroenterology and hepatology 2020;9(4):569-585
Mogroside V Protects against Hepatic Steatosis in Mice on a High-Fat Diet and LO2 Cells Treated with Free Fatty Acids via AMPK Activation.
Li L, Zheng W, Wang C, Qi J, Li H
Evidence-based complementary and alternative medicine : eCAM 2020;2020:7826874
Evidence-based complementary and alternative medicine : eCAM 2020;2020:7826874
Mild Hypothermia Attenuates Hepatic Ischemia-Reperfusion Injury through Regulating the JAK2/STAT3-CPT1a-Dependent Fatty Acid β-Oxidation.
Wang W, Hu X, Xia Z, Liu Z, Zhong Z, Lu Z, Liu A, Ye S, Cao Q, Wang Y, Zhu F, Ye Q
Oxidative medicine and cellular longevity 2020;2020:5849794
Oxidative medicine and cellular longevity 2020;2020:5849794
TET1 promotes fatty acid oxidation and inhibits NAFLD progression by hydroxymethylation of PPARα promoter.
Wang J, Zhang Y, Zhuo Q, Tseng Y, Wang J, Ma Y, Zhang J, Liu J
Nutrition & metabolism 2020;17:46
Nutrition & metabolism 2020;17:46
Effects of canagliflozin on growth and metabolic reprograming in hepatocellular carcinoma cells: Multi-omics analysis of metabolomics and absolute quantification proteomics (iMPAQT).
Nakano D, Kawaguchi T, Iwamoto H, Hayakawa M, Koga H, Torimura T
PloS one 2020;15(4):e0232283
PloS one 2020;15(4):e0232283
UCHL1 regulates oxidative activity in skeletal muscle.
Gao H, Antony R, Srinivasan R, Wu P, Wang X, Li Y
PloS one 2020;15(11):e0241716
PloS one 2020;15(11):e0241716
Fenofibrate-induced mitochondrial dysfunction and metabolic reprogramming reversal: the anti-tumor effects in gastric carcinoma cells mediated by the PPAR pathway.
Chen L, Peng J, Wang Y, Jiang H, Wang W, Dai J, Tang M, Wei Y, Kuang H, Xu G, Xu H, Zhou F
American journal of translational research 2020;12(2):428-446
American journal of translational research 2020;12(2):428-446
High-Intensity Interval Training Restores Glycolipid Metabolism and Mitochondrial Function in Skeletal Muscle of Mice With Type 2 Diabetes.
Zheng L, Rao Z, Guo Y, Chen P, Xiao W
Frontiers in endocrinology 2020;11:561
Frontiers in endocrinology 2020;11:561
Critical biomarkers for myocardial damage by fine particulate matter: Focused on PPARα-regulated energy metabolism.
Zhang Z, Su H, Ahmed RZ, Zheng Y, Jin X
Environmental pollution (Barking, Essex : 1987) 2020 Sep;264:114659
Environmental pollution (Barking, Essex : 1987) 2020 Sep;264:114659
Sirtuin 3-mediated deacetylation of acyl-CoA synthetase family member 3 by protocatechuic acid attenuates non-alcoholic fatty liver disease.
Sun R, Kang X, Zhao Y, Wang Z, Wang R, Fu R, Li Y, Hu Y, Wang Z, Shan W, Zhou J, Tian X, Yao J
British journal of pharmacology 2020 Sep;177(18):4166-4180
British journal of pharmacology 2020 Sep;177(18):4166-4180
SGLT2 Inhibition Mediates Protection from Diabetic Kidney Disease by Promoting Ketone Body-Induced mTORC1 Inhibition.
Tomita I, Kume S, Sugahara S, Osawa N, Yamahara K, Yasuda-Yamahara M, Takeda N, Chin-Kanasaki M, Kaneko T, Mayoux E, Mark M, Yanagita M, Ogita H, Araki SI, Maegawa H
Cell metabolism 2020 Sep 1;32(3):404-419.e6
Cell metabolism 2020 Sep 1;32(3):404-419.e6
Uncovering the mechanism of Astragali Radix against nephrotic syndrome by intergrating lipidomics and network pharmacology.
Li AP, Yang L, Cui T, Zhang LC, Liu YT, Yan Y, Li K, Qin XM
Phytomedicine : international journal of phytotherapy and phytopharmacology 2020 Oct;77:153274
Phytomedicine : international journal of phytotherapy and phytopharmacology 2020 Oct;77:153274
Peroxisomal proliferator-activated receptor α-b deficiency induces the reprogramming of nutrient metabolism in zebrafish.
Li LY, Lv HB, Jiang ZY, Qiao F, Chen LQ, Zhang ML, Du ZY
The Journal of physiology 2020 Oct;598(20):4537-4553
The Journal of physiology 2020 Oct;598(20):4537-4553
Protective effect of Yi-Qi-Huo-Xue Decoction against ischemic heart disease by regulating cardiac lipid metabolism.
Li FH, Huang XL, Wang H, Guo SW, Li P
Chinese journal of natural medicines 2020 Oct;18(10):779-792
Chinese journal of natural medicines 2020 Oct;18(10):779-792
A substrate-trapping strategy to find E3 ubiquitin ligase substrates identifies Parkin and TRIM28 targets.
Watanabe M, Saeki Y, Takahashi H, Ohtake F, Yoshida Y, Kasuga Y, Kondo T, Yaguchi H, Suzuki M, Ishida H, Tanaka K, Hatakeyama S
Communications biology 2020 Oct 20;3(1):592
Communications biology 2020 Oct 20;3(1):592
A novel bile acid analog, A17, ameliorated non-alcoholic steatohepatitis in high-fat diet-fed hamsters.
Wang Y, Zhu Y, Niu J, Deng Q, Guo S, Jiang H, Peng Z, Xue Y, Peng H, Xuan L, Pan G
Toxicology and applied pharmacology 2020 Oct 1;404:115169
Toxicology and applied pharmacology 2020 Oct 1;404:115169
Effect and mechanism of ginsenoside Rg1-regulating hepatic steatosis in HepG2 cells induced by free fatty acid.
Gao Y, Zhang S, Li J, Zhao J, Xiao Q, Zhu Y, Zhang J, Huang W
Bioscience, biotechnology, and biochemistry 2020 Nov;84(11):2228-2240
Bioscience, biotechnology, and biochemistry 2020 Nov;84(11):2228-2240
Melanoma Persister Cells Are Tolerant to BRAF/MEK Inhibitors via ACOX1-Mediated Fatty Acid Oxidation.
Shen S, Faouzi S, Souquere S, Roy S, Routier E, Libenciuc C, André F, Pierron G, Scoazec JY, Robert C
Cell reports 2020 Nov 24;33(8):108421
Cell reports 2020 Nov 24;33(8):108421
CPT1A Over-Expression Increases Reactive Oxygen Species in the Mitochondria and Promotes Antioxidant Defenses in Prostate Cancer.
Joshi M, Kim J, D'Alessandro A, Monk E, Bruce K, Elajaili H, Nozik-Grayck E, Goodspeed A, Costello JC, Schlaepfer IR
Cancers 2020 Nov 18;12(11)
Cancers 2020 Nov 18;12(11)
RIPK3 Orchestrates Fatty Acid Metabolism in Tumor-Associated Macrophages and Hepatocarcinogenesis.
Wu L, Zhang X, Zheng L, Zhao H, Yan G, Zhang Q, Zhou Y, Lei J, Zhang J, Wang J, Xin R, Jiang L, Peng J, Chen Q, Lam SM, Shui G, Miao H, Li Y
Cancer immunology research 2020 May;8(5):710-721
Cancer immunology research 2020 May;8(5):710-721
Sirt3 modulates fatty acid oxidation and attenuates cisplatin-induced AKI in mice.
Li M, Li CM, Ye ZC, Huang J, Li Y, Lai W, Peng H, Lou TQ
Journal of cellular and molecular medicine 2020 May;24(9):5109-5121
Journal of cellular and molecular medicine 2020 May;24(9):5109-5121
Modulation of SIRT1-mediated signaling cascades in the liver contributes to the amelioration of nonalcoholic steatohepatitis in high fat fed middle-aged LDL receptor knockout mice by dihydromyricetin.
Zeng Y, Hua YQ, Wang W, Zhang H, Xu XL
Biochemical pharmacology 2020 May;175:113927
Biochemical pharmacology 2020 May;175:113927
Yin Zhi Huang, a traditional Chinese herbal formula, ameliorates diet-induced obesity and hepatic steatosis by activating the AMPK/SREBP-1 and the AMPK/ACC/CPT1A pathways.
Yao Q, Li S, Cheng X, Zou Y, Shen Y, Zhang S
Annals of translational medicine 2020 Mar;8(5):231
Annals of translational medicine 2020 Mar;8(5):231
Low Expression of Sirtuin 1 in the Dairy Cows with Mild Fatty Liver Alters Hepatic Lipid Metabolism.
Li Y, Zou S, Ding H, Hao N, Huang Y, Tang J, Cheng J, Feng S, Li J, Wang X, Wu J
Animals : an open access journal from MDPI 2020 Mar 27;10(4)
Animals : an open access journal from MDPI 2020 Mar 27;10(4)
Prohibitin 2 deficiency impairs cardiac fatty acid oxidation and causes heart failure.
Wu D, Jian C, Peng Q, Hou T, Wu K, Shang B, Zhao M, Wang Y, Zheng W, Ma Q, Li CY, Cheng H, Wang X, Zhao L
Cell death & disease 2020 Mar 12;11(3):181
Cell death & disease 2020 Mar 12;11(3):181
Severe hypoglycemia exacerbates myocardial dysfunction and metabolic remodeling in diabetic mice.
Huang L, Zhou Y, Chen Z, Zhang M, Zhan Z, Wang L, Liu L
Molecular and cellular endocrinology 2020 Mar 1;503:110692
Molecular and cellular endocrinology 2020 Mar 1;503:110692
Hepatic HuR modulates lipid homeostasis in response to high-fat diet.
Zhang Z, Zong C, Jiang M, Hu H, Cheng X, Ni J, Yi X, Jiang B, Tian F, Chang MW, Su W, Zhu L, Li J, Xiang X, Miao C, Gorospe M, de Cabo R, Dou Y, Ju Z, Yang J, Jiang C, Yang Z, Wang W
Nature communications 2020 Jun 16;11(1):3067
Nature communications 2020 Jun 16;11(1):3067
Identification of FABP5 as an immunometabolic marker in human hepatocellular carcinoma.
Liu F, Liu W, Zhou S, Yang C, Tian M, Jia G, Wang H, Zhu B, Feng M, Lu Y, Qiao T, Wang X, Cao W, Wang X, Shi Y, Wu D
Journal for immunotherapy of cancer 2020 Jul;8(2)
Journal for immunotherapy of cancer 2020 Jul;8(2)
Spexin protects cardiomyocytes from hypoxia-induced metabolic and mitochondrial dysfunction.
Liu Y, Sun L, Zheng L, Su M, Liu H, Wei Y, Li D, Wang Y, Dai C, Gong Y, Zhao C, Li Y
Naunyn-Schmiedeberg's archives of pharmacology 2020 Jan;393(1):25-33
Naunyn-Schmiedeberg's archives of pharmacology 2020 Jan;393(1):25-33
Flavonoids extracted from mulberry (Morus alba L.) leaf improve skeletal muscle mitochondrial function by activating AMPK in type 2 diabetes.
Meng Q, Qi X, Fu Y, Chen Q, Cheng P, Yu X, Sun X, Wu J, Li W, Zhang Q, Li Y, Wang A, Bian H
Journal of ethnopharmacology 2020 Feb 10;248:112326
Journal of ethnopharmacology 2020 Feb 10;248:112326
Hepatic Synaptotagmin 1 is involved in the remodelling of liver plasma- membrane lipid composition and gene expression in male Apoe-deficient mice consuming a Western diet.
Sancho-Knapik S, Pastor O, Barranquero C, Herrera Marcos LV, Guillén N, Arnal C, Gascón S, Navarro MA, Rodríguez-Yoldi MJ, Busto R, Lasunción MA, Osada J
Biochimica et biophysica acta. Molecular and cell biology of lipids 2020 Dec;1865(12):158790
Biochimica et biophysica acta. Molecular and cell biology of lipids 2020 Dec;1865(12):158790
Targeting Fat Oxidation in Mouse Prostate Cancer Decreases Tumor Growth and Stimulates Anti-Cancer Immunity.
Guth A, Monk E, Agarwal R, Bergman BC, Zemski-Berry KA, Minic A, Jordan K, Schlaepfer IR
International journal of molecular sciences 2020 Dec 18;21(24)
International journal of molecular sciences 2020 Dec 18;21(24)
Dynamic Cardiolipin Synthesis Is Required for CD8(+) T Cell Immunity.
Corrado M, Edwards-Hicks J, Villa M, Flachsmann LJ, Sanin DE, Jacobs M, Baixauli F, Stanczak M, Anderson E, Azuma M, Quintana A, Curtis JD, Clapes T, Grzes KM, Kabat AM, Kyle R, Patterson AE, Geltink RK, Amulic B, Steward CG, Strathdee D, Trompouki E, O'Sullivan D, Pearce EJ, Pearce EL
Cell metabolism 2020 Dec 1;32(6):981-995.e7
Cell metabolism 2020 Dec 1;32(6):981-995.e7
Hypertensive Rats Treated Chronically With N(ω)-Nitro-L-Arginine Methyl Ester (L-NAME) Induced Disorder of Hepatic Fatty Acid Metabolism and Intestinal Pathophysiology.
Li B, He X, Lei SS, Zhou FC, Zhang NY, Chen YH, Wang YZ, Su J, Yu JJ, Li LZ, Zheng X, Luo R, Kołodyńska D, Xiong S, Lv GY, Chen SH
Frontiers in pharmacology 2019;10:1677
Frontiers in pharmacology 2019;10:1677
UPLC-QTOF/MS-based metabolomics analysis of plasma reveals an effect of Xue-Fu-Zhu-Yu capsules on blood-stasis syndrome in CHD rats.
Zhao Y, Nie S, Yi M, Wu N, Wang W, Zhang Z, Yao Y, Wang D
Journal of ethnopharmacology 2019 Sep 15;241:111908
Journal of ethnopharmacology 2019 Sep 15;241:111908
Lin28 enhances de novo fatty acid synthesis to promote cancer progression via SREBP-1.
Zhang Y, Li C, Hu C, Wu Q, Cai Y, Xing S, Lu H, Wang L, Huang D, Sun L, Li T, He X, Zhong X, Wang J, Gao P, Smith ZJ, Jia W, Zhang H
EMBO reports 2019 Oct 4;20(10):e48115
EMBO reports 2019 Oct 4;20(10):e48115
The contrary intracellular and extracellular functions of PEDF in HCC development.
Li C, Huang Z, Zhu L, Yu X, Gao T, Feng J, Hong H, Yin H, Zhou T, Qi W, Yang Z, Liu C, Yang X, Gao G
Cell death & disease 2019 Oct 3;10(10):742
Cell death & disease 2019 Oct 3;10(10):742
Apple Polyphenol Extract Alleviates High-Fat-Diet-Induced Hepatic Steatosis in Male C57BL/6 Mice by Targeting LKB1/AMPK Pathway.
Li D, Liu F, Wang X, Li X
Journal of agricultural and food chemistry 2019 Nov 6;67(44):12208-12218
Journal of agricultural and food chemistry 2019 Nov 6;67(44):12208-12218
Loss of ubiquitin-conjugating enzyme E2 (Ubc9) in macrophages exacerbates multiple low-dose streptozotocin-induced diabetes by attenuating M2 macrophage polarization.
Wang F, Sun F, Luo J, Yue T, Chen L, Zhou H, Zhang J, Yang C, Luo X, Zhou Q, Zhu H, Li J, Yang P, Xiong F, Yu Q, Zhang H, Zhang W, Xu A, Zhou Z, Lu Q, Eizirik DL, Zhang S, Wang CY
Cell death & disease 2019 Nov 26;10(12):892
Cell death & disease 2019 Nov 26;10(12):892
Regulation effects of rosemary (Rosmarinus officinalis Linn.) on hepatic lipid metabolism in OA induced NAFLD rats.
Wang SJ, Chen Q, Liu MY, Yu HY, Xu JQ, Wu JQ, Zhang Y, Wang T
Food & function 2019 Nov 1;10(11):7356-7365
Food & function 2019 Nov 1;10(11):7356-7365
Role of ketone signaling in the hepatic response to fasting.
Geisler CE, Ghimire S, Bogan RL, Renquist BJ
American journal of physiology. Gastrointestinal and liver physiology 2019 May 1;316(5):G623-G631
American journal of physiology. Gastrointestinal and liver physiology 2019 May 1;316(5):G623-G631
Integrated Metabolomics and Lipidomics Analyses Reveal Metabolic Reprogramming in Human Glioma with IDH1 Mutation.
Zhou L, Wang Z, Hu C, Zhang C, Kovatcheva-Datchary P, Yu D, Liu S, Ren F, Wang X, Li Y, Hou X, Piao H, Lu X, Zhang Y, Xu G
Journal of proteome research 2019 Mar 1;18(3):960-969
Journal of proteome research 2019 Mar 1;18(3):960-969
MSC-regulated lncRNA MACC1-AS1 promotes stemness and chemoresistance through fatty acid oxidation in gastric cancer.
He W, Liang B, Wang C, Li S, Zhao Y, Huang Q, Liu Z, Yao Z, Wu Q, Liao W, Zhang S, Liu Y, Xiang Y, Liu J, Shi M
Oncogene 2019 Jun;38(23):4637-4654
Oncogene 2019 Jun;38(23):4637-4654
Impairment of Fatty Acid Oxidation in Alveolar Epithelial Cells Mediates Acute Lung Injury.
Cui H, Xie N, Banerjee S, Ge J, Guo S, Liu G
American journal of respiratory cell and molecular biology 2019 Feb;60(2):167-178
American journal of respiratory cell and molecular biology 2019 Feb;60(2):167-178
Coenzyme Q10 attenuates high-fat diet-induced non-alcoholic fatty liver disease through activation of the AMPK pathway.
Chen K, Chen X, Xue H, Zhang P, Fang W, Chen X, Ling W
Food & function 2019 Feb 20;10(2):814-823
Food & function 2019 Feb 20;10(2):814-823
Fe(3)O(4)@OA@Poloxamer nanoparticles lower triglyceride in hepatocytes through liposuction effect and nano-enzyme effect.
Sun Y, Shi F, Niu Y, Zhang Y, Xiong F
Colloids and surfaces. B, Biointerfaces 2019 Dec 1;184:110528
Colloids and surfaces. B, Biointerfaces 2019 Dec 1;184:110528
Adropin reduces blood glucose levels in mice by limiting hepatic glucose production.
Thapa D, Xie B, Manning JR, Zhang M, Stoner MW, Huckestein BR, Edmunds LR, Zhang X, Dedousis NL, O'Doherty RM, Jurczak MJ, Scott I
Physiological reports 2019 Apr;7(8):e14043
Physiological reports 2019 Apr;7(8):e14043
CD36 plays a negative role in the regulation of lipophagy in hepatocytes through an AMPK-dependent pathway.
Li Y, Yang P, Zhao L, Chen Y, Zhang X, Zeng S, Wei L, Varghese Z, Moorhead JF, Chen Y, Ruan XZ
Journal of lipid research 2019 Apr;60(4):844-855
Journal of lipid research 2019 Apr;60(4):844-855
Inhibition of soluble epoxide hydrolase ameliorates hyperhomocysteinemia-induced hepatic steatosis by enhancing β-oxidation of fatty acid in mice.
Yao L, Cao B, Cheng Q, Cai W, Ye C, Liang J, Liu W, Tan L, Yan M, Li B, He J, Hwang SH, Zhang X, Wang C, Ai D, Hammock BD, Zhu Y
American journal of physiology. Gastrointestinal and liver physiology 2019 Apr 1;316(4):G527-G538
American journal of physiology. Gastrointestinal and liver physiology 2019 Apr 1;316(4):G527-G538
A novel approach to target hypoxic cancer cells via combining β-oxidation inhibitor etomoxir with radiation.
Dheeraj A, Agarwal C, Schlaepfer IR, Raben D, Singh R, Agarwal R, Deep G
Hypoxia (Auckland, N.Z.) 2018;6:23-33
Hypoxia (Auckland, N.Z.) 2018;6:23-33
GLP-1 receptor agonist ameliorates obesity-induced chronic kidney injury via restoring renal metabolism homeostasis.
Wang C, Li L, Liu S, Liao G, Li L, Chen Y, Cheng J, Lu Y, Liu J
PloS one 2018;13(3):e0193473
PloS one 2018;13(3):e0193473
Combinatorial treatment of Rhizoma Paridis saponins and sorafenib overcomes the intolerance of sorafenib.
Yao J, Man S, Dong H, Yang L, Ma L, Gao W
The Journal of steroid biochemistry and molecular biology 2018 Oct;183:159-166
The Journal of steroid biochemistry and molecular biology 2018 Oct;183:159-166
YAP1 enhances NF-κB-dependent and independent effects on clock-mediated unfolded protein responses and autophagy in sarcoma.
Rivera-Reyes A, Ye S, E Marino G, Egolf S, E Ciotti G, Chor S, Liu Y, Posimo JM, Park PMC, Pak K, Babichev Y, Sostre-Colón J, Tameire F, Leli NM, Koumenis C, C Brady D, Mancuso A, Weber K, Gladdy R, Qi J, Eisinger-Mathason TSK
Cell death & disease 2018 Oct 31;9(11):1108
Cell death & disease 2018 Oct 31;9(11):1108
Rosiglitazone ameliorates palmitic acid-induced cytotoxicity in TM4 Sertoli cells.
Ge X, Pan P, Jing J, Hu X, Chen L, Qiu X, Ma R, Jueraitetibaike K, Huang X, Yao B
Reproductive biology and endocrinology : RB&E 2018 Oct 17;16(1):98
Reproductive biology and endocrinology : RB&E 2018 Oct 17;16(1):98
The protein acetylase GCN5L1 modulates hepatic fatty acid oxidation activity via acetylation of the mitochondrial β-oxidation enzyme HADHA.
Thapa D, Wu K, Stoner MW, Xie B, Zhang M, Manning JR, Lu Z, Li JH, Chen Y, Gucek M, Playford MP, Mehta NN, Harmon D, O'Doherty RM, Jurczak MJ, Sack MN, Scott I
The Journal of biological chemistry 2018 Nov 16;293(46):17676-17684
The Journal of biological chemistry 2018 Nov 16;293(46):17676-17684
IL-25 stimulates M2 macrophage polarization and thereby promotes mitochondrial respiratory capacity and lipolysis in adipose tissues against obesity.
Feng J, Li L, Ou Z, Li Q, Gong B, Zhao Z, Qi W, Zhou T, Zhong J, Cai W, Yang X, Zhao A, Gao G, Yang Z
Cellular & molecular immunology 2018 May;15(5):493-505
Cellular & molecular immunology 2018 May;15(5):493-505
Protective effects of dioscin against fructose-induced renal damage via adjusting Sirt3-mediated oxidative stress, fibrosis, lipid metabolism and inflammation.
Qiao Y, Xu L, Tao X, Yin L, Qi Y, Xu Y, Han X, Tang Z, Ma X, Liu K, Peng J
Toxicology letters 2018 Mar 1;284:37-45
Toxicology letters 2018 Mar 1;284:37-45
Fibroblast growth factor 21 increases hepatic oxidative capacity but not physical activity or energy expenditure in hepatic peroxisome proliferator-activated receptor γ coactivator-1α-deficient mice.
Fletcher JA, Linden MA, Sheldon RD, Meers GM, Morris EM, Butterfield A, Perfield JW 2nd, Rector RS, Thyfault JP
Experimental physiology 2018 Mar 1;103(3):408-418
Experimental physiology 2018 Mar 1;103(3):408-418
Scutellaria baicalensis regulates FFA metabolism to ameliorate NAFLD through the AMPK-mediated SREBP signaling pathway.
Chen Q, Liu M, Yu H, Li J, Wang S, Zhang Y, Qiu F, Wang T
Journal of natural medicines 2018 Jun;72(3):655-666
Journal of natural medicines 2018 Jun;72(3):655-666
Disrupting SOD1 activity inhibits cell growth and enhances lipid accumulation in nasopharyngeal carcinoma.
Li S, Fu L, Tian T, Deng L, Li H, Xia W, Gong Q
Cell communication and signaling : CCS 2018 Jun 11;16(1):28
Cell communication and signaling : CCS 2018 Jun 11;16(1):28
Chronic low-dose exposure of nonylphenol alters energy homeostasis in the reproductive system of female rats.
Di QN, Cao WX, Xu R, Lu L, Xu Q, Wang XB
Toxicology and applied pharmacology 2018 Jun 1;348:67-75
Toxicology and applied pharmacology 2018 Jun 1;348:67-75
N-3 polyunsaturated fatty acids ameliorate hepatic steatosis via the PPAR-α/CPT-1α pathway in a mouse model of parenteral nutrition.
Tian F, Wang J, Sun H, Yang J, Wang P, Wan S, Gao X, Zhang L, Li J, Wang X
Biochemical and biophysical research communications 2018 Jul 2;501(4):974-981
Biochemical and biophysical research communications 2018 Jul 2;501(4):974-981
Polyacetylene glycoside attenuates ischemic kidney injury by co-inhibiting inflammation, mitochondria dysfunction and lipotoxicity.
Zhou Y, Du D, Liu S, Zhao M, Yuan Y, Li L, Chen Y, Lu Y, Cheng J, Liu J
Life sciences 2018 Jul 1;204:55-64
Life sciences 2018 Jul 1;204:55-64
Zoledronate dysregulates fatty acid metabolism in renal tubular epithelial cells to induce nephrotoxicity.
Cheng L, Ge M, Lan Z, Ma Z, Chi W, Kuang W, Sun K, Zhao X, Liu Y, Feng Y, Huang Y, Luo M, Li L, Zhang B, Hu X, Xu L, Liu X, Huo Y, Deng H, Yang J, Xi Q, Zhang Y, Siegenthaler JA, Chen L
Archives of toxicology 2018 Jan;92(1):469-485
Archives of toxicology 2018 Jan;92(1):469-485
PIK3R3 regulates PPARα expression to stimulate fatty acid β-oxidation and decrease hepatosteatosis.
Yang X, Fu Y, Hu F, Luo X, Hu J, Wang G
Experimental & molecular medicine 2018 Jan 19;50(1):e431
Experimental & molecular medicine 2018 Jan 19;50(1):e431
Adipose-specific lipin1 overexpression in mice protects against alcohol-induced liver injury.
Zhang W, Zhong W, Sun Q, Sun X, Zhou Z
Scientific reports 2018 Jan 11;8(1):408
Scientific reports 2018 Jan 11;8(1):408
The role of autophagy during murine primordial follicle assembly.
Sun YC, Wang YY, Sun XF, Cheng SF, Li L, Zhao Y, Shen W, Chen H
Aging 2018 Feb 5;10(2):197-211
Aging 2018 Feb 5;10(2):197-211
Quiescent Endothelial Cells Upregulate Fatty Acid β-Oxidation for Vasculoprotection via Redox Homeostasis.
Kalucka J, Bierhansl L, Conchinha NV, Missiaen R, Elia I, Brüning U, Scheinok S, Treps L, Cantelmo AR, Dubois C, de Zeeuw P, Goveia J, Zecchin A, Taverna F, Morales-Rodriguez F, Brajic A, Conradi LC, Schoors S, Harjes U, Vriens K, Pilz GA, Chen R, Cubbon R, Thienpont B, Cruys B, Wong BW, Ghesquière B, Dewerchin M, De Bock K, Sagaert X, Jessberger S, Jones EAV, Gallez B, Lambrechts D, Mazzone M, Eelen G, Li X, Fendt SM, Carmeliet P
Cell metabolism 2018 Dec 4;28(6):881-894.e13
Cell metabolism 2018 Dec 4;28(6):881-894.e13
Paeoniflorin Ameliorates Fructose-Induced Insulin Resistance and Hepatic Steatosis by Activating LKB1/AMPK and AKT Pathways.
Li YC, Qiao JY, Wang BY, Bai M, Shen JD, Cheng YX
Nutrients 2018 Aug 5;10(8)
Nutrients 2018 Aug 5;10(8)
Mitochondria-targeted ubiquinone (MitoQ) enhances acetaldehyde clearance by reversing alcohol-induced posttranslational modification of aldehyde dehydrogenase 2: A molecular mechanism of protection against alcoholic liver disease.
Hao L, Sun Q, Zhong W, Zhang W, Sun X, Zhou Z
Redox biology 2018 Apr;14:626-636
Redox biology 2018 Apr;14:626-636
Fish oil feeding reverses hepatomegaly and disrupted hepatic function due to the lack of FXR signaling.
Miyata M, Shinno K, Kinoshita T, Kinoshita Y, Sugiura Y
The Journal of toxicological sciences 2017;42(6):671-681
The Journal of toxicological sciences 2017;42(6):671-681
A signature of enhanced lipid metabolism, lipid peroxidation and aldehyde stress in therapy-induced senescence.
Flor AC, Wolfgeher D, Wu D, Kron SJ
Cell death discovery 2017;3:17075
Cell death discovery 2017;3:17075
Kupffer cells activation promoted binge drinking-induced fatty liver by activating lipolysis in white adipose tissues.
Zhao YY, Yang R, Xiao M, Guan MJ, Zhao N, Zeng T
Toxicology 2017 Sep 1;390:53-60
Toxicology 2017 Sep 1;390:53-60
Attenuation of hepatic steatosis by purple sweet potato colour is associated with blocking Src/ERK/C/EBPβ signalling in high-fat-diet-treated mice.
Wang X, Zhang ZF, Zheng GH, Wang AM, Sun CH, Qin SP, Zhuang J, Lu J, Ma DF, Zheng YL
Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme 2017 Oct;42(10):1082-1091
Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme 2017 Oct;42(10):1082-1091
Mitochondrial Priming by CD28.
Klein Geltink RI, O'Sullivan D, Corrado M, Bremser A, Buck MD, Buescher JM, Firat E, Zhu X, Niedermann G, Caputa G, Kelly B, Warthorst U, Rensing-Ehl A, Kyle RL, Vandersarren L, Curtis JD, Patterson AE, Lawless S, Grzes K, Qiu J, Sanin DE, Kretz O, Huber TB, Janssens S, Lambrecht BN, Rambold AS, Pearce EJ, Pearce EL
Cell 2017 Oct 5;171(2):385-397.e11
Cell 2017 Oct 5;171(2):385-397.e11
p38α MAPK antagonizing JNK to control the hepatic fat accumulation in pediatric patients onset intestinal failure.
Xiao Y, Wang J, Yan W, Zhou K, Cao Y, Cai W
Cell death & disease 2017 Oct 12;8(10):e3110
Cell death & disease 2017 Oct 12;8(10):e3110
Targeted Metabolomics Reveals Abnormal Hepatic Energy Metabolism by Depletion of β-Carotene Oxygenase 2 in Mice.
Wu L, Guo X, Lyu Y, Clarke SL, Lucas EA, Smith BJ, Hildebrand D, Wang W, Medeiros DM, Shen X, Lin D
Scientific reports 2017 Nov 7;7(1):14624
Scientific reports 2017 Nov 7;7(1):14624
Xyloketal B Attenuates Fatty Acid-Induced Lipid Accumulation via the SREBP-1c Pathway in NAFLD Models.
Zhang Y, Meng T, Zuo L, Bei Y, Zhang Q, Su Z, Huang Y, Pang J, Xiang Q, Yang H
Marine drugs 2017 Jun 3;15(6)
Marine drugs 2017 Jun 3;15(6)
Aerobic capacity mediates susceptibility for the transition from steatosis to steatohepatitis.
Morris EM, McCoin CS, Allen JA, Gastecki ML, Koch LG, Britton SL, Fletcher JA, Fu X, Ding WX, Burgess SC, Rector RS, Thyfault JP
The Journal of physiology 2017 Jul 15;595(14):4909-4926
The Journal of physiology 2017 Jul 15;595(14):4909-4926
Pharmacological inhibition of NOX4 ameliorates alcohol-induced liver injury in mice through improving oxidative stress and mitochondrial function.
Sun Q, Zhang W, Zhong W, Sun X, Zhou Z
Biochimica et biophysica acta. General subjects 2017 Jan;1861(1 Pt A):2912-2921
Biochimica et biophysica acta. General subjects 2017 Jan;1861(1 Pt A):2912-2921
Calycosin attenuates triglyceride accumulation and hepatic fibrosis in murine model of non-alcoholic steatohepatitis via activating farnesoid X receptor.
Duan X, Meng Q, Wang C, Liu Z, Liu Q, Sun H, Sun P, Yang X, Huo X, Peng J, Liu K
Phytomedicine : international journal of phytotherapy and phytopharmacology 2017 Feb 15;25:83-92
Phytomedicine : international journal of phytotherapy and phytopharmacology 2017 Feb 15;25:83-92
RNA Binding Protein Ybx2 Regulates RNA Stability During Cold-Induced Brown Fat Activation.
Xu D, Xu S, Kyaw AMM, Lim YC, Chia SY, Chee Siang DT, Alvarez-Dominguez JR, Chen P, Leow MK, Sun L
Diabetes 2017 Dec;66(12):2987-3000
Diabetes 2017 Dec;66(12):2987-3000
Lipid catabolism inhibition sensitizes prostate cancer cells to antiandrogen blockade.
Flaig TW, Salzmann-Sullivan M, Su LJ, Zhang Z, Joshi M, Gijón MA, Kim J, Arcaroli JJ, Van Bokhoven A, Lucia MS, La Rosa FG, Schlaepfer IR
Oncotarget 2017 Aug 22;8(34):56051-56065
Oncotarget 2017 Aug 22;8(34):56051-56065
Hepatic overproduction of 13-HODE due to ALOX15 upregulation contributes to alcohol-induced liver injury in mice.
Zhang W, Zhong W, Sun Q, Sun X, Zhou Z
Scientific reports 2017 Aug 21;7(1):8976
Scientific reports 2017 Aug 21;7(1):8976
Medium-chain fatty acid reduces lipid accumulation by regulating expression of lipid-sensing genes in human liver cells with steatosis.
Wang B, Fu J, Li L, Gong D, Wen X, Yu P, Zeng Z
International journal of food sciences and nutrition 2016;67(3):288-97
International journal of food sciences and nutrition 2016;67(3):288-97
Sodium sulfite promotes the assembly and secretion of very low-density lipoprotein in HL-7702 hepatocytes.
Bai J, Lei P, Zhao C, Wang Y, Yan D, Yang S
Toxicology reports 2016;3:98-104
Toxicology reports 2016;3:98-104
Dysregulation of hepatic cAMP levels via altered Pde4b expression plays a critical role in alcohol-induced steatosis.
Avila DV, Barker DF, Zhang J, McClain CJ, Barve S, Gobejishvili L
The Journal of pathology 2016 Sep;240(1):96-107
The Journal of pathology 2016 Sep;240(1):96-107
Molecular regulation of apoptotic machinery and lipid metabolism by mTORC1/mTORC2 dual inhibitors in preclinical models of HER2+/PIK3CAmut breast cancer.
Qian J, Chen Y, Meng T, Ma L, Meng L, Wang X, Yu T, Zask A, Shen J, Yu K
Oncotarget 2016 Oct 11;7(41):67071-67086
Oncotarget 2016 Oct 11;7(41):67071-67086
High-fat diet enhances stemness and tumorigenicity of intestinal progenitors.
Beyaz S, Mana MD, Roper J, Kedrin D, Saadatpour A, Hong SJ, Bauer-Rowe KE, Xifaras ME, Akkad A, Arias E, Pinello L, Katz Y, Shinagare S, Abu-Remaileh M, Mihaylova MM, Lamming DW, Dogum R, Guo G, Bell GW, Selig M, Nielsen GP, Gupta N, Ferrone CR, Deshpande V, Yuan GC, Orkin SH, Sabatini DM, Yilmaz ÖH
Nature 2016 Mar 3;531(7592):53-8
Nature 2016 Mar 3;531(7592):53-8
TXNIP regulates myocardial fatty acid oxidation via miR-33a signaling.
Chen J, Young ME, Chatham JC, Crossman DK, Dell'Italia LJ, Shalev A
American journal of physiology. Heart and circulatory physiology 2016 Jul 1;311(1):H64-75
American journal of physiology. Heart and circulatory physiology 2016 Jul 1;311(1):H64-75
Effects of a block in cysteine catabolism on energy balance and fat metabolism in mice.
Niewiadomski J, Zhou JQ, Roman HB, Liu X, Hirschberger LL, Locasale JW, Stipanuk MH
Annals of the New York Academy of Sciences 2016 Jan;1363(1):99-115
Annals of the New York Academy of Sciences 2016 Jan;1363(1):99-115
HDAC4 mediates IFN-γ induced disruption of energy expenditure-related gene expression by repressing SIRT1 transcription in skeletal muscle cells.
Fang M, Fan Z, Tian W, Zhao Y, Li P, Xu H, Zhou B, Zhang L, Wu X, Xu Y
Biochimica et biophysica acta 2016 Feb;1859(2):294-305
Biochimica et biophysica acta 2016 Feb;1859(2):294-305
Foxp3 and Toll-like receptor signaling balance T(reg) cell anabolic metabolism for suppression.
Gerriets VA, Kishton RJ, Johnson MO, Cohen S, Siska PJ, Nichols AG, Warmoes MO, de Cubas AA, MacIver NJ, Locasale JW, Turka LA, Wells AD, Rathmell JC
Nature immunology 2016 Dec;17(12):1459-1466
Nature immunology 2016 Dec;17(12):1459-1466
A Novel Function of Hepatic FOG2 in Insulin Sensitivity and Lipid Metabolism Through PPARα.
Guo Y, Yu J, Deng J, Liu B, Xiao Y, Li K, Xiao F, Yuan F, Liu Y, Chen S, Guo F
Diabetes 2016 Aug;65(8):2151-63
Diabetes 2016 Aug;65(8):2151-63
Acetyl-coenzyme A carboxylase alpha promotion of glucose-mediated fatty acid synthesis enhances survival of hepatocellular carcinoma in mice and patients.
Wang MD, Wu H, Fu GB, Zhang HL, Zhou X, Tang L, Dong LW, Qin CJ, Huang S, Zhao LH, Zeng M, Wu MC, Yan HX, Wang HY
Hepatology (Baltimore, Md.) 2016 Apr;63(4):1272-86
Hepatology (Baltimore, Md.) 2016 Apr;63(4):1272-86
Diet rich in Docosahexaenoic Acid/Eicosapentaenoic Acid robustly ameliorates hepatic steatosis and insulin resistance in seipin deficient lipodystrophy mice.
Xu P, Wang H, Kayoumu A, Wang M, Huang W, Liu G
Nutrition & metabolism 2015;12:58
Nutrition & metabolism 2015;12:58
Efficacy of Berberine in Patients with Non-Alcoholic Fatty Liver Disease.
Yan HM, Xia MF, Wang Y, Chang XX, Yao XZ, Rao SX, Zeng MS, Tu YF, Feng R, Jia WP, Liu J, Deng W, Jiang JD, Gao X
PloS one 2015;10(8):e0134172
PloS one 2015;10(8):e0134172
AMP-Activated Protein Kinase Interacts with the Peroxisome Proliferator-Activated Receptor Delta to Induce Genes Affecting Fatty Acid Oxidation in Human Macrophages.
Kemmerer M, Finkernagel F, Cavalcante MF, Abdalla DS, Müller R, Brüne B, Namgaladze D
PloS one 2015;10(6):e0130893
PloS one 2015;10(6):e0130893
Niche-dependent regulations of metabolic balance in high-fat diet-induced diabetic mice by mesenchymal stromal cells.
Ji AT, Chang YC, Fu YJ, Lee OK, Ho JH
Diabetes 2015 Mar;64(3):926-36
Diabetes 2015 Mar;64(3):926-36
Proteomics-based metabolic modeling reveals that fatty acid oxidation (FAO) controls endothelial cell (EC) permeability.
Patella F, Schug ZT, Persi E, Neilson LJ, Erami Z, Avanzato D, Maione F, Hernandez-Fernaud JR, Mackay G, Zheng L, Reid S, Frezza C, Giraudo E, Fiorio Pla A, Anderson K, Ruppin E, Gottlieb E, Zanivan S
Molecular & cellular proteomics : MCP 2015 Mar;14(3):621-34
Molecular & cellular proteomics : MCP 2015 Mar;14(3):621-34
Astrocyte Elevated Gene-1 (AEG-1) Regulates Lipid Homeostasis.
Robertson CL, Srivastava J, Siddiq A, Gredler R, Emdad L, Rajasekaran D, Akiel M, Shen XN, Corwin F, Sundaresan G, Zweit J, Croniger C, Gao X, Ghosh S, Hylemon PB, Subler MA, Windle JJ, Fisher PB, Sarkar D
The Journal of biological chemistry 2015 Jul 17;290(29):18227-18236
The Journal of biological chemistry 2015 Jul 17;290(29):18227-18236
High metastaticgastric and breast cancer cells consume oleic acid in an AMPK dependent manner.
Li S, Zhou T, Li C, Dai Z, Che D, Yao Y, Li L, Ma J, Yang X, Gao G
PloS one 2014;9(5):e97330
PloS one 2014;9(5):e97330
Fatty acid oxidation is dispensable for human macrophage IL-4-induced polarization.
Namgaladze D, Brüne B
Biochimica et biophysica acta 2014 Sep;1841(9):1329-35
Biochimica et biophysica acta 2014 Sep;1841(9):1329-35
HIF-1-mediated suppression of acyl-CoA dehydrogenases and fatty acid oxidation is critical for cancer progression.
Huang D, Li T, Li X, Zhang L, Sun L, He X, Zhong X, Jia D, Song L, Semenza GL, Gao P, Zhang H
Cell reports 2014 Sep 25;8(6):1930-1942
Cell reports 2014 Sep 25;8(6):1930-1942
A compound heterozygous mutation in GPD1 causes hepatomegaly, steatohepatitis, and hypertriglyceridemia.
Joshi M, Eagan J, Desai NK, Newton SA, Towne MC, Marinakis NS, Esteves KM, De Ferranti S, Bennett MJ, McIntyre A, Beggs AH, Berry GT, Agrawal PB
European journal of human genetics : EJHG 2014 Oct;22(10):1229-32
European journal of human genetics : EJHG 2014 Oct;22(10):1229-32
Inhibition of macrophage fatty acid β-oxidation exacerbates palmitate-induced inflammatory and endoplasmic reticulum stress responses.
Namgaladze D, Lips S, Leiker TJ, Murphy RC, Ekroos K, Ferreiros N, Geisslinger G, Brüne B
Diabetologia 2014 May;57(5):1067-77
Diabetologia 2014 May;57(5):1067-77
Identification of 5' AMP-activated kinase as a target of reactive aldehydes during chronic ingestion of high concentrations of ethanol.
Shearn CT, Backos DS, Orlicky DJ, Smathers-McCullough RL, Petersen DR
The Journal of biological chemistry 2014 May 30;289(22):15449-62
The Journal of biological chemistry 2014 May 30;289(22):15449-62
SIRT1 activation by methylene blue, a repurposed drug, leads to AMPK-mediated inhibition of steatosis and steatohepatitis.
Shin SY, Kim TH, Wu H, Choi YH, Kim SG
European journal of pharmacology 2014 Mar 15;727:115-24
European journal of pharmacology 2014 Mar 15;727:115-24
KLF15 is a molecular link between endoplasmic reticulum stress and insulin resistance.
Jung DY, Chalasani U, Pan N, Friedline RH, Prosdocimo DA, Nam M, Azuma Y, Maganti R, Yu K, Velagapudi A, O'Sullivan-Murphy B, Sartoretto JL, Jain MK, Cooper MP, Urano F, Kim JK, Gray S
PloS one 2013;8(10):e77851
PloS one 2013;8(10):e77851
Chinese medicine formula lingguizhugan decoction improves Beta-oxidation and metabolism of Fatty Acid in high-fat-diet-induced rat model of Fatty liver disease.
Liu T, Yang LL, Zou L, Li DF, Wen HZ, Zheng PY, Xing LJ, Song HY, Tang XD, Ji G
Evidence-based complementary and alternative medicine : eCAM 2013;2013:429738
Evidence-based complementary and alternative medicine : eCAM 2013;2013:429738
Binge ethanol-induced HDAC3 down-regulates Cpt1α expression leading to hepatic steatosis and injury.
Kirpich I, Zhang J, Gobejishvili L, Kharebava G, Barker D, Ghare S, Joshi-Barve S, McClain CJ, Barve S
Alcoholism, clinical and experimental research 2013 Nov;37(11):1920-9
Alcoholism, clinical and experimental research 2013 Nov;37(11):1920-9
Anti-miR-33 therapy does not alter the progression of atherosclerosis in low-density lipoprotein receptor-deficient mice.
Marquart TJ, Wu J, Lusis AJ, Baldán Á
Arteriosclerosis, thrombosis, and vascular biology 2013 Mar;33(3):455-8
Arteriosclerosis, thrombosis, and vascular biology 2013 Mar;33(3):455-8
An iTRAQ proteomic study reveals an association between diet-induced enhanced fatty acid metabolism and the development of glucose intolerance in prediabetic mice.
Ho JH, Lee OK, Fu YJ, Shih HT, Tseng CY, Chung CC, Han CL, Chen YJ
Journal of proteome research 2013 Mar 1;12(3):1120-33
Journal of proteome research 2013 Mar 1;12(3):1120-33
Role of sirtuin 1 in the regulation of hepatic gene expression by thyroid hormone.
Thakran S, Sharma P, Attia RR, Hori RT, Deng X, Elam MB, Park EA
The Journal of biological chemistry 2013 Jan 11;288(2):807-18
The Journal of biological chemistry 2013 Jan 11;288(2):807-18
SILAC-based proteomics of human primary endothelial cell morphogenesis unveils tumor angiogenic markers.
Zanivan S, Maione F, Hein MY, Hernández-Fernaud JR, Ostasiewicz P, Giraudo E, Mann M
Molecular & cellular proteomics : MCP 2013 Dec;12(12):3599-611
Molecular & cellular proteomics : MCP 2013 Dec;12(12):3599-611
An active metabolite of oltipraz (M2) increases mitochondrial fuel oxidation and inhibits lipogenesis in the liver by dually activating AMPK.
Kim TH, Eom JS, Lee CG, Yang YM, Lee YS, Kim SG
British journal of pharmacology 2013 Apr;168(7):1647-61
British journal of pharmacology 2013 Apr;168(7):1647-61
Binge alcohol-induced microvesicular liver steatosis and injury are associated with down-regulation of hepatic Hdac 1, 7, 9, 10, 11 and up-regulation of Hdac 3.
Kirpich I, Ghare S, Zhang J, Gobejishvili L, Kharebava G, Barve SJ, Barker D, Moghe A, McClain CJ, Barve S
Alcoholism, clinical and experimental research 2012 Sep;36(9):1578-86
Alcoholism, clinical and experimental research 2012 Sep;36(9):1578-86
Genomic alterations with impact on survival in esophageal squamous cell carcinoma identified by array comparative genomic hybridization.
Shi ZZ, Liang JW, Zhan T, Wang BS, Lin DC, Liu SG, Hao JJ, Yang H, Zhang Y, Zhan QM, Zhang KT, Wang MR
Genes, chromosomes & cancer 2011 Jul;50(7):518-26
Genes, chromosomes & cancer 2011 Jul;50(7):518-26
Establishing a relationship between prolactin and altered fatty acid β-oxidation via carnitine palmitoyl transferase 1 in breast cancer cells.
Linher-Melville K, Zantinge S, Sanli T, Gerstein H, Tsakiridis T, Singh G
BMC cancer 2011 Feb 4;11:56
BMC cancer 2011 Feb 4;11:56
Expression of miR-33 from an SREBP2 intron inhibits cholesterol export and fatty acid oxidation.
Gerin I, Clerbaux LA, Haumont O, Lanthier N, Das AK, Burant CF, Leclercq IA, MacDougald OA, Bommer GT
The Journal of biological chemistry 2010 Oct 29;285(44):33652-61
The Journal of biological chemistry 2010 Oct 29;285(44):33652-61
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HepG2 cells were subjected to SDS PAGE followed by western blot with 15184-1-AP(CPT1A antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of Hela cells, using CPT1A antibody 15184-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- IP Result of anti-CPT1A (IP:15184-1-AP, 3ug; Detection:15184-1-AP 1:300) with HepG2 cells lysate 2000ug.
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human liver cancer using 15184-1-AP(CPT1A antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human liver cancer using 15184-1-AP(CPT1A antibody) at dilution of 1:100 (under 40x lens)
- Sample type
- tissue
