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- Antigen structure
- References [19]
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- Western blot [1]
- Immunoprecipitation [1]
- Immunohistochemistry [2]
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- Product number
- 66039-1-Ig - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#66039-1-Ig, RRID:AB_11041710
- Product name
- CPT1A antibody
- Antibody type
- Monoclonal
- Description
- KD/KO validated CPT1A antibody (Cat. #66039-1-Ig) is a mouse monoclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- 5D8G9
- Vial size
- 20ul, 150ul
Submitted references Farnesoid X receptor overexpression prevents hepatic steatosis through inhibiting AIM2 inflammasome activation in nonalcoholic fatty liver disease.
Regulation of astrocyte metabolism by mitochondrial translocator protein 18kDa.
Angelica sinensis polysaccharide ameliorates nonalcoholic fatty liver disease via restoring estrogen-related receptor α expression in liver.
L-carnitine alleviates cardiac microvascular dysfunction in diabetic cardiomyopathy by enhancing PINK1-Parkin-dependent mitophagy through the CPT1a-PHB2-PARL pathways.
Impaired FXR-CPT1a signaling contributes to parenteral nutrition-induced villus atrophy in short-bowel syndrome.
Altered Peroxisome Proliferator-Activated Receptor Alpha Signaling in Variably Diseased Peripheral Arterial Segments.
Berberrubine, a Main Metabolite of Berberine, Alleviates Non-Alcoholic Fatty Liver Disease via Modulating Glucose and Lipid Metabolism and Restoring Gut Microbiota.
The serum acylcarnitines profile in epileptic children treated with valproic acid and the protective roles of peroxisome proliferator-activated receptor a activation in valproic acid-induced liver injury.
Lipidomics reveals the potential mechanism of honokiol against adenine-induced chronic kidney disease.
Hawk tea prevents high-fat diet-induced obesity in mice by activating the AMPK/ACC/SREBP1c signaling pathways and regulating the gut microbiota.
PD-1 signaling facilitates activation of lymphoid tissue inducer cells by restraining fatty acid oxidation.
MicroRNA-377-3p inhibits hepatocellular carcinoma growth and metastasis through negative regulation of CPT1C-mediated fatty acid oxidation.
The lncRNA MIAT regulates CPT-1a mediated cardiac hypertrophy through m(6)A RNA methylation reading protein Ythdf2.
Multi-Omics Analysis of Fatty Acid Metabolism in Thyroid Carcinoma.
CEPT1-Mediated Phospholipogenesis Regulates Endothelial Cell Function and Ischemia-Induced Angiogenesis Through PPARα.
Etomoxir regulates the differentiation of male germ cells by specifically reducing H3K27ac level.
Curcumin-enhanced antitumor effects of sorafenib via regulating the metabolism and tumor microenvironment.
Metabolomics reveal mitochondrial and fatty acid metabolism disorders that contribute to the development of DKD in T2DM patients.
Circadian and Dopaminergic Regulation of Fatty Acid Oxidation Pathway Genes in Retina and Photoreceptor Cells.
Xu S, Kong L, Li L, Wang C, Gu J, Luo H, Meng Q
Biochimica et biophysica acta. Molecular basis of disease 2024 Feb;1870(2):166930
Biochimica et biophysica acta. Molecular basis of disease 2024 Feb;1870(2):166930
Regulation of astrocyte metabolism by mitochondrial translocator protein 18kDa.
Firth W, Robb JL, Stewart D, Pye KR, Bamford R, Oguro-Ando A, Beall C, Ellacott KL
bioRxiv : the preprint server for biology 2023 Oct 2;
bioRxiv : the preprint server for biology 2023 Oct 2;
Angelica sinensis polysaccharide ameliorates nonalcoholic fatty liver disease via restoring estrogen-related receptor α expression in liver.
Luo L, Zhang H, Chen W, Zheng Z, He Z, Wang H, Wang K, Zhang Y
Phytotherapy research : PTR 2023 Nov;37(11):5407-5417
Phytotherapy research : PTR 2023 Nov;37(11):5407-5417
L-carnitine alleviates cardiac microvascular dysfunction in diabetic cardiomyopathy by enhancing PINK1-Parkin-dependent mitophagy through the CPT1a-PHB2-PARL pathways.
Li S, Liu M, Chen J, Chen Y, Yin M, Zhou Y, Li Q, Xu F, Li Y, Yan X, Xia Y, Chen A, Lu D, Li C, Shen L, Chen Z, Qian J, Ge J
Acta physiologica (Oxford, England) 2023 Jul;238(3):e13975
Acta physiologica (Oxford, England) 2023 Jul;238(3):e13975
Impaired FXR-CPT1a signaling contributes to parenteral nutrition-induced villus atrophy in short-bowel syndrome.
Zhao Y, Feng H, Wang Y, Jiang L, Yan J, Cai W
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Jan;37(1):e22713
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Jan;37(1):e22713
Altered Peroxisome Proliferator-Activated Receptor Alpha Signaling in Variably Diseased Peripheral Arterial Segments.
Engel C, Meade R, Harroun N, Penrose A, Shafqat M, Jin X, DeSilva G, Semenkovich C, Zayed M
Frontiers in cardiovascular medicine 2022;9:834199
Frontiers in cardiovascular medicine 2022;9:834199
Berberrubine, a Main Metabolite of Berberine, Alleviates Non-Alcoholic Fatty Liver Disease via Modulating Glucose and Lipid Metabolism and Restoring Gut Microbiota.
Yang S, Cao S, Li C, Zhang J, Liu C, Qiu F, Kang N
Frontiers in pharmacology 2022;13:913378
Frontiers in pharmacology 2022;13:913378
The serum acylcarnitines profile in epileptic children treated with valproic acid and the protective roles of peroxisome proliferator-activated receptor a activation in valproic acid-induced liver injury.
Ma Y, Wang M, Guo S, Li T, Liu X, Zhao L
Frontiers in pharmacology 2022;13:1048728
Frontiers in pharmacology 2022;13:1048728
Lipidomics reveals the potential mechanism of honokiol against adenine-induced chronic kidney disease.
Liu X, Gao L, Huang X, Deng R, Wei X, Lu J, Li S
Frontiers in pharmacology 2022;13:1019629
Frontiers in pharmacology 2022;13:1019629
Hawk tea prevents high-fat diet-induced obesity in mice by activating the AMPK/ACC/SREBP1c signaling pathways and regulating the gut microbiota.
Tao W, Cao W, Yu B, Chen H, Gong R, Luorong Q, Luo J, Yao L, Zhang D
Food & function 2022 Jun 6;13(11):6056-6071
Food & function 2022 Jun 6;13(11):6056-6071
PD-1 signaling facilitates activation of lymphoid tissue inducer cells by restraining fatty acid oxidation.
Wu D, Hu L, Han M, Deng Y, Zhang Y, Ren G, Zhao X, Li Z, Li P, Zhang Y, Chen S, Li J, Shi Y, Xue J, Wang P, Zhong C
Nature metabolism 2022 Jul;4(7):867-882
Nature metabolism 2022 Jul;4(7):867-882
MicroRNA-377-3p inhibits hepatocellular carcinoma growth and metastasis through negative regulation of CPT1C-mediated fatty acid oxidation.
Zhang T, Zhang Y, Liu J, Ma Y, Ye Q, Yan X, Ding L
Cancer & metabolism 2022 Jan 20;10(1):2
Cancer & metabolism 2022 Jan 20;10(1):2
The lncRNA MIAT regulates CPT-1a mediated cardiac hypertrophy through m(6)A RNA methylation reading protein Ythdf2.
Yang Y, Mbikyo MB, Zhang J, Zhang Y, Zhang N, Li Z
Cell death discovery 2022 Apr 5;8(1):167
Cell death discovery 2022 Apr 5;8(1):167
Multi-Omics Analysis of Fatty Acid Metabolism in Thyroid Carcinoma.
Lu J, Zhang Y, Sun M, Ding C, Zhang L, Kong Y, Cai M, Miccoli P, Ma C, Yue X
Frontiers in oncology 2021;11:737127
Frontiers in oncology 2021;11:737127
CEPT1-Mediated Phospholipogenesis Regulates Endothelial Cell Function and Ischemia-Induced Angiogenesis Through PPARα.
Zayed MA, Jin X, Yang C, Belaygorod L, Engel C, Desai K, Harroun N, Saffaf O, Patterson BW, Hsu FF, Semenkovich CF
Diabetes 2021 Feb;70(2):549-561
Diabetes 2021 Feb;70(2):549-561
Etomoxir regulates the differentiation of male germ cells by specifically reducing H3K27ac level.
Xu Y, Xie J
BMC developmental biology 2021 Feb 1;21(1):5
BMC developmental biology 2021 Feb 1;21(1):5
Curcumin-enhanced antitumor effects of sorafenib via regulating the metabolism and tumor microenvironment.
Man S, Yao J, Lv P, Liu Y, Yang L, Ma L
Food & function 2020 Jul 22;11(7):6422-6432
Food & function 2020 Jul 22;11(7):6422-6432
Metabolomics reveal mitochondrial and fatty acid metabolism disorders that contribute to the development of DKD in T2DM patients.
Li L, Wang C, Yang H, Liu S, Lu Y, Fu P, Liu J
Molecular bioSystems 2017 Oct 24;13(11):2392-2400
Molecular bioSystems 2017 Oct 24;13(11):2392-2400
Circadian and Dopaminergic Regulation of Fatty Acid Oxidation Pathway Genes in Retina and Photoreceptor Cells.
Vancura P, Wolloscheck T, Baba K, Tosini G, Iuvone PM, Spessert R
PloS one 2016;11(10):e0164665
PloS one 2016;11(10):e0164665
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- L02 cells were subjected to SDS PAGE followed by western blot with 66039-1-Ig(CPT1A antibody) at dilution of 1:500
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- IP Result of anti-CPT1A (IP:66039-1-Ig, 4ug; Detection:66039-1-Ig 1:500) with MCF-7 cells lysate 1200ug.
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human heart using 66039-1-Ig(CPT1A antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The CPT1A antibody from Proteintech is a mouse monoclonal antibody to a fusion protein of human CPT1A. This antibody recognizes human antigen. The CPT1A antibody has been validated for the following applications: ELISA, WB, IHC, IP analysis.
