66862-1-Ig

antibody from Proteintech Group

Targeting: PCK1 PEPCK-C

Western blot (Data presented on provider website)

ELISA (Data presented on provider website)

Immunocytochemistry (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

66862-1-Ig

Provider

Proteintech Group

Product name

PCK1 antibody

Antibody type

Monoclonal

Description

PCK1 antibody (Cat. #66862-1-Ig) is a mouse monoclonal antibody that shows reactivity with mouse, rat, pig, human and has been validated for the following applications: IF, IHC, WB, ELISA.

Reactivity

Human, Mouse, Rat, Porcine

Host

Mouse

Conjugate

Unconjugated

Isotype

IgG

Antibody clone number

2F11B5

Vial size

20ul, 150ul

References

Submitted references

Pck1 Deficiency Drives Mitochondrial Dysfunction and Cellular Senescence in Adipocytes.

Lei Y, Yang M, Jiang X, Zhang Y, Chen Y, Xie W, Dai Q, Qin W, Deng X, Zhang X, Zhou Z, Huang G, Liu X
Aging cell 2026 Apr;25(4):e70462

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PCK1 inhibits cGAS-STING activation by consumption of GTP to promote tumor immune evasion.

Qin W, Duan Y, Hu Z, Hou Y, Wen T, Ouyang Y, Wang Z, Sun X, Chen X, Wang KL, Luo S, Ji G, Shen Y, Dong B, Lin Y, Tian Q, Guo Z, Wu S, Xiao L, Li M, Xiao L, Wu Q, Meng Y, Liu G, Zhang W, Duan S, Bai X, Liu T, He J, Lu Z, Xu D
The Journal of experimental medicine 2025 May 5;222(5)

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Pathology-oriented multiplexing enables integrative disease mapping.

Kuehl M, Okabayashi Y, Wong MN, Gernhold L, Gut G, Kaiser N, Schwerk M, Gräfe SK, Ma FY, Tanevski J, Schäfer PSL, Mezher S, Sarabia Del Castillo J, Goldbeck-Strieder T, Zolotareva O, Hartung M, Delgado Chaves FM, Klinkert L, Gnirck AC, Spehr M, Fleck D, Joodaki M, Parra V, Shaigan M, Diebold M, Prinz M, Kranz J, Kux JM, Braun F, Kretz O, Wu H, Grahammer F, Heins S, Zimmermann M, Haas F, Kylies D, Wanner N, Czogalla J, Dumoulin B, Zolotarev N, Lindenmeyer M, Karlson P, Nyengaard JR, Sebode M, Weidemann S, Wiech T, Groene HJ, Tomas NM, Meyer-Schwesinger C, Kuppe C, Kramann R, Karras A, Bruneval P, Tharaux PL, Pastene D, Yard B, Schaub JA, McCown PJ, Pyle L, Choi YJ, Yokoo T, Baumbach J, Sáez PJ, Costa I, Turner JE, Hodgin JB, Saez-Rodriguez J, Huber TB, Bjornstad P, Kretzler M, Lenoir O, Nikolic-Paterson DJ, Pelkmans L, Bonn S, Puelles VG
Nature 2025 Aug;644(8076):516-526

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Porcine reproductive and respiratory syndrome virus activates lipid synthesis through a ROS-dependent AKT/PCK1/INSIG/SREBPs axis.

Ma YX, Han YQ, Wang PZ, Wang MY, Yang GY, Li JL, Wang J, Chu BB
International journal of biological macromolecules 2024 Dec;282(Pt 1):136720