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- Antibody Data
- Antigen structure
- References [5]
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- Validations
- Immunocytochemistry [1]
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- Product number
- HPA027452 - Provider product page
- Provider
- Atlas Antibodies
- Proper citation
- Atlas Antibodies Cat#HPA027452, RRID:AB_1854490
- Product name
- Anti-PPP1R8
- Antibody type
- Polyclonal
- Description
- Polyclonal Antibody against Human PPP1R8, Gene description: protein phosphatase 1, regulatory subunit 8, Alternative Gene Names: ard-1, ARD1, NIPP-1, NIPP1, PRO2047, Validated applications: ICC, WB, Uniprot ID: Q12972, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µl
- Concentration
- 0.1 mg/ml
- Storage
- Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Handling
- The antibody solution should be gently mixed before use.
Submitted references Alternating binding and p97-mediated dissociation of SDS22 and I3 recycles active PP1 between holophosphatases
PP1 regulatory subunit NIPP1 regulates transcription of E2F1 target genes following DNA damage
Protein phosphatase 1 activity controls a balance between collective and single cell modes of migration
The deletion of the protein phosphatase 1 regulator NIPP1 in testis causes hyperphosphorylation and degradation of the histone methyltransferase EZH2
A substrate-trapping strategy for protein phosphatase PP1 holoenzymes using hypoactive subunit fusions
Kueck A, van den Boom J, Koska S, Ron D, Meyer H
Proceedings of the National Academy of Sciences 2024;121(36)
Proceedings of the National Academy of Sciences 2024;121(36)
PP1 regulatory subunit NIPP1 regulates transcription of E2F1 target genes following DNA damage
Hanaki S, Habara M, Masaki T, Maeda K, Sato Y, Nakanishi M, Shimada M
Cancer Science 2021;112(7):2739-2752
Cancer Science 2021;112(7):2739-2752
Protein phosphatase 1 activity controls a balance between collective and single cell modes of migration
Chen Y, Kotian N, Aranjuez G, Chen L, Messer C, Burtscher A, Sawant K, Ramel D, Wang X, McDonald J
eLife 2020;9
eLife 2020;9
The deletion of the protein phosphatase 1 regulator NIPP1 in testis causes hyperphosphorylation and degradation of the histone methyltransferase EZH2
Ferreira M, Verbinnen I, Fardilha M, Van Eynde A, Bollen M
Journal of Biological Chemistry 2018;293(47):18031-18039
Journal of Biological Chemistry 2018;293(47):18031-18039
A substrate-trapping strategy for protein phosphatase PP1 holoenzymes using hypoactive subunit fusions
Wu D, De Wever V, Derua R, Winkler C, Beullens M, Van Eynde A, Bollen M
Journal of Biological Chemistry 2018;293(39):15152-15162
Journal of Biological Chemistry 2018;293(39):15152-15162
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Supportive validation
- Submitted by
- Atlas Antibodies (provider)
- Main image
- Experimental details
- Immunofluorescent staining of human cell line A-431 shows localization to nuclear speckles.
- Sample type
- Human
