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- Product number
- ABIN2847257 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Heart and Neural Crest Derivatives Expressed 1 (HAND1) (AA 76-105), (Center) antibody
- Antibody type
- Polyclonal
- Description
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Reactivity
- Human
- Host
- Rabbit
- Epitope
- AA 76-105, Center
- Antibody clone number
- RB34361
- Vial size
- 80 μL
- Storage
- HAND1 Antibody (Center) can be refrigerated at 2-8°C for up to 6 months. For long term storage, place the at -20°C.
Submitted references A functional genetic study identifies HAND1 mutations in septation defects of the human heart.
HAND1 gene expression is negatively regulated by the High Mobility Group A1 proteins and is drastically reduced in human thyroid carcinomas.
A loss-of-function mutation in the binding domain of HAND1 predicts hypoplasia of the human hearts.
MEF2-dependent recruitment of the HAND1 transcription factor results in synergistic activation of target promoters.
Reamon-Buettner SM, Ciribilli Y, Traverso I, Kuhls B, Inga A, Borlak J
Human molecular genetics 2009 Oct 1;18(19):3567-78
Human molecular genetics 2009 Oct 1;18(19):3567-78
HAND1 gene expression is negatively regulated by the High Mobility Group A1 proteins and is drastically reduced in human thyroid carcinomas.
Martinez Hoyos J, Ferraro A, Sacchetti S, Keller S, De Martino I, Borbone E, Pallante P, Fedele M, Montanaro D, Esposito F, Cserjesi P, Chiariotti L, Troncone G, Fusco A
Oncogene 2009 Feb 12;28(6):876-85
Oncogene 2009 Feb 12;28(6):876-85
A loss-of-function mutation in the binding domain of HAND1 predicts hypoplasia of the human hearts.
Reamon-Buettner SM, Ciribilli Y, Inga A, Borlak J
Human molecular genetics 2008 May 15;17(10):1397-405
Human molecular genetics 2008 May 15;17(10):1397-405
MEF2-dependent recruitment of the HAND1 transcription factor results in synergistic activation of target promoters.
Morin S, Pozzulo G, Robitaille L, Cross J, Nemer M
The Journal of biological chemistry 2005 Sep 16;280(37):32272-8
The Journal of biological chemistry 2005 Sep 16;280(37):32272-8
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