28034-1-AP

antibody from Proteintech Group

Targeting: FADS2 D6D, DES6, FADSD6, LLCDL2, SLL0262, TU13

Western blot (Data presented on provider website)

ELISA (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

28034-1-AP

Provider

Proteintech Group

Product name

FADS2-Specific antibody

Antibody type

Polyclonal

Description

FADS2-Specific antibody (Cat. #28034-1-AP) is a rabbit polyclonal antibody that shows reactivity with Human, Mouse and has been validated for the following applications: IHC, WB, ELISA.

Reactivity

Human, Mouse

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

20ul, 150ul

References

Submitted references

Investigating the Role of Lactate-Related Genes in Radiotherapy Resistance of Lung Cancer by Integrated Bioinformatics and Experiment Validation.

Li Q, Shen L, Yang Y, Tai G, Zhu Q, Liu C, Ge Q, Yi Q
Journal of Cancer 2025;16(11):3296-3313

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Roseburia hominis enriched by baicalin reverses the non-response to metformin via upregulating linolenic acid metabolism.

Miao Z, Long J, Huang B, Yan D, Wang A
iScience 2025 Nov 21;28(11):113892

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Breaking the synergism of iron overload and miR-122 to rescue lipid accumulation and peroxidation in MASLD.

Tang Y, Gao Z, Yang J, Li C, Wang W, Wu C, Wu M, Li M, Wu H, Sun Y, Zhang H, Chai Y, Xie F, Qian J, Shen H, Wang D
Pharmacological research 2025 May;215:107728

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Comparing Soy and Milk Protein Regulation of Hepatic Omega-3 Fatty Acid Biosynthesis.

Gonzalez-Soto M, Woods SE, MacLeod BW, Smorenburg JN, DesOrmeaux GJ, Holloway GP, Rotarescu RD, Green MR, Metherel AH, Mutch DM
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Jul 15;39(13):e70805

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Metabolic Interplay in Acute Lung Injury: PARK7 Integrates FADS1/2-Dependent PUFA Metabolism and H3K14 Lactylation to Attenuate Endothelial Ferroptosis and Dysfunction.

Xu J, Wang Y, Mao W, Wei T, Li Y, Song J, Zhang C, Chen X, Chen C, Xu Q, Wu X, Song Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Dec;12(46):e08725

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Zeb1 mediates EMT/plasticity-associated ferroptosis sensitivity in cancer cells by regulating lipogenic enzyme expression and phospholipid composition.

Schwab A, Rao Z, Zhang J, Gollowitzer A, Siebenkäs K, Bindel N, D'Avanzo E, van Roey R, Hajjaj Y, Özel E, Armstark I, Bereuter L, Su F, Grander J, Bonyadi Rad E, Groenewoud A, Engel FB, Bell GW, Henry WS, Angeli JPF, Stemmler MP, Brabletz S, Koeberle A, Brabletz T
Nature cell biology 2024 Sep;26(9):1470-1481

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Polyamine Pathway Inhibitor DENSPM Suppresses Lipid Metabolism in Pheochromocytoma Cell Line.

Ghayee HK, Costa KA, Xu Y, Hatch HM, Rodriguez M, Straight SC, Bustamante M, Yu F, Smagulova F, Bowden JA, Tevosian SG
International journal of molecular sciences 2024 Sep 18;25(18)

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Identification of Ferroptosis-Related Gene in Age-Related Macular Degeneration Using Machine Learning.

Zhu M, Yu J
Immunity, inflammation and disease 2024 Dec;12(12):e70059

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E3 ubiquitin ligase Siah1 aggravates NAFLD through Scp2 ubiquitination.

Zhu Z, Hu X, Liu K, Li J, Fan K, Wang H, Wang L, He L, Ma Y, Guan R, Wang Z
International immunopharmacology 2023 Nov;124(Pt A):110897

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The Effects of Early-Life Stress on Liver Transcriptomics and the Protective Role of EPA in a Mouse Model of Early-Life-Stress-Induced Adolescent Depression.

Zhao J, Ye L, Liu Z, Wu J, Deng D, An L, Bai S, Yang L, Liu B, Shi Y, Liu Z, Zhang R
International journal of molecular sciences 2023 Aug 23;24(17)

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FADS2-dependent fatty acid desaturation dictates cellular sensitivity to ferroptosis and permissiveness for hepatitis C virus replication.

Yamane D, Hayashi Y, Matsumoto M, Nakanishi H, Imagawa H, Kohara M, Lemon SM, Ichi I
Cell chemical biology 2022 May 19;29(5):799-810.e4

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Multimodal Metabolic Imaging Reveals Pigment Reduction and Lipid Accumulation in Metastatic Melanoma.

Lee HJ, Chen Z, Collard M, Chen F, Chen JG, Wu M, Alani RM, Cheng JX
BME frontiers 2021;2021:9860123

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Sorafenib kills liver cancer cells by disrupting SCD1-mediated synthesis of monounsaturated fatty acids via the ATP-AMPK-mTOR-SREBP1 signaling pathway.

Liu G, Kuang S, Cao R, Wang J, Peng Q, Sun C
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Sep;33(9):10089-10103