Antibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
Reference
Comment
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- Product number
- 12648-1-AP - Provider product page

- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#12648-1-AP, RRID:AB_2161890
- Product name
- PDE9A antibody
- Antibody type
- Polyclonal
- Description
- PDE9A antibody (Cat. #12648-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Hederagenin Attenuates Cardiac Remodeling by Targeting Phosphodiesterase 9A.
NEURL1 acts as a candidate suppressor in bladder cancer by down-regulating PDE9A.
E3 ubiquitin ligase CHIP facilitates cAMP and cGMP signalling cross-talk by polyubiquitinating PDE9A.
A novel phosphodiesterase 9A inhibitor LW33 protects against ischemic stroke through the cGMP/PKG/CREB pathway.
Chen L, Zhou X, You Y, Chen J, Peng B, Deng Y, Ji S, Yang Y, Chen X, Liu H, Yang S, Kwan HY, Jin W, Zhang L, Wang Y, Zhao X, Liu Y
Phytotherapy research : PTR 2026 May;40(5):2710-2729
Phytotherapy research : PTR 2026 May;40(5):2710-2729
NEURL1 acts as a candidate suppressor in bladder cancer by down-regulating PDE9A.
Qiu Y, Ruan H, Ji D, Cao N
In vitro cellular & developmental biology. Animal 2025 Jun;61(6):681-693
In vitro cellular & developmental biology. Animal 2025 Jun;61(6):681-693
E3 ubiquitin ligase CHIP facilitates cAMP and cGMP signalling cross-talk by polyubiquitinating PDE9A.
Hao X, Hu Z, Li M, Zhang S, Tang M, Hao C, Qi S, Liang Y, Almeida MF, Smith K, Zuo C, Feng Y, Guo M, Ma D, Li S, Wang Z, Sun Y, Deng Z, Mao C, Xia Z, Jiang Y, Gao Y, Xu Y, Schisler JC, Shi C
The EMBO journal 2025 Feb;44(4):1249-1273
The EMBO journal 2025 Feb;44(4):1249-1273
A novel phosphodiesterase 9A inhibitor LW33 protects against ischemic stroke through the cGMP/PKG/CREB pathway.
You JY, Liu XW, Bao YX, Shen ZN, Wang Q, He GY, Lu J, Zhang JG, Chen JW, Liu PQ
European journal of pharmacology 2022 Jun 15;925:174987
European journal of pharmacology 2022 Jun 15;925:174987
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- mouse skeletal muscle tissue were subjected to SDS PAGE followed by western blot with 12648-1-AP(PDE9A antibody) at dilution of 1:400
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- The PDE9A antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human PDE9A. This antibody recognizes human, mouse, rat antigen. The PDE9A antibody has been validated for the following applications: ELISA, WB, IHC analysis.