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- References [7]
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- Validations
- Western blot [1]
- Immunocytochemistry [1]
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- Product number
- 21196-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#21196-1-AP, RRID:AB_10732957
- Product name
- EYA3 antibody
- Antibody type
- Polyclonal
- Description
- EYA3 antibody (Cat. #21196-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references miR-342-5p downstream to Notch enhances arterialization of endothelial cells in response to shear stress by repressing MYC.
Merkel Cell Carcinoma Sensitivity to EZH2 Inhibition Is Mediated by SIX1 Derepression.
Both a hypoxia-inducible EYA3 and a histone acetyltransferase p300 function as coactivators of SIX5 to mediate tumorigenesis and cancer progression.
The EYA3 tyrosine phosphatase activity promotes pulmonary vascular remodeling in pulmonary arterial hypertension.
Analysis of EYA3 Phosphorylation by Src Kinase Identifies Residues Involved in Cell Proliferation.
WDR1 is a novel EYA3 substrate and its dephosphorylation induces modifications of the cellular actin cytoskeleton.
Structure-activity relationships of benzbromarone metabolites and derivatives as EYA inhibitory anti-angiogenic agents.
Zhang X, Sun J, Zhang P, Wen T, Wang R, Liang L, Yang Z, Li J, Zhang J, Che B, Feng X, Liu X, Han H, Yan X
Molecular therapy. Nucleic acids 2023 Jun 13;32:343-358
Molecular therapy. Nucleic acids 2023 Jun 13;32:343-358
Merkel Cell Carcinoma Sensitivity to EZH2 Inhibition Is Mediated by SIX1 Derepression.
Gartin AK, Frost TC, Cushman CH, Leeper BA, Gokhale PC, DeCaprio JA
The Journal of investigative dermatology 2022 Oct;142(10):2783-2792.e15
The Journal of investigative dermatology 2022 Oct;142(10):2783-2792.e15
Both a hypoxia-inducible EYA3 and a histone acetyltransferase p300 function as coactivators of SIX5 to mediate tumorigenesis and cancer progression.
Yang C, Liu H
Annals of translational medicine 2022 Jul;10(13):752
Annals of translational medicine 2022 Jul;10(13):752
The EYA3 tyrosine phosphatase activity promotes pulmonary vascular remodeling in pulmonary arterial hypertension.
Wang Y, Pandey RN, York AJ, Mallela J, Nichols WC, Hu YC, Molkentin JD, Wikenheiser-Brokamp KA, Hegde RS
Nature communications 2019 Sep 12;10(1):4143
Nature communications 2019 Sep 12;10(1):4143
Analysis of EYA3 Phosphorylation by Src Kinase Identifies Residues Involved in Cell Proliferation.
Ionescu AE, Mentel M, Munteanu CVA, Sima LE, Martin EC, Necula-Petrareanu G, Szedlacsek SE
International journal of molecular sciences 2019 Dec 13;20(24)
International journal of molecular sciences 2019 Dec 13;20(24)
WDR1 is a novel EYA3 substrate and its dephosphorylation induces modifications of the cellular actin cytoskeleton.
Mentel M, Ionescu AE, Puscalau-Girtu I, Helm MS, Badea RA, Rizzoli SO, Szedlacsek SE
Scientific reports 2018 Feb 13;8(1):2910
Scientific reports 2018 Feb 13;8(1):2910
Structure-activity relationships of benzbromarone metabolites and derivatives as EYA inhibitory anti-angiogenic agents.
Pandey RN, Wang TS, Tadjuidje E, McDonald MG, Rettie AE, Hegde RS
PloS one 2013;8(12):e84582
PloS one 2013;8(12):e84582
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- L02 cells were subjected to SDS PAGE followed by western blot with 21196-1-AP(EYA3 antibody) at dilution of 1:500
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of Hela cells, using EYA3 antibody 21196-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
- Sample type
- cell line
