18374-1-AP

antibody from Proteintech Group

Targeting: ANGPTL4 ARP4, FIAF, HFARP, NL2, PGAR, pp1158

Provider product page for 18374-1-AP

Western blot

ELISA

Immunocytochemistry

Immunoprecipitation

Immunohistochemistry

Antibody data

Antibody Data
Antigen structure
References [27]
Comments [0]
Validations
Western blot [1]
Immunocytochemistry [1]

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Product number: 18374-1-AP - Provider product page
Provider: Proteintech Group
Product name: ANGPTL4 antibody
Antibody type: Polyclonal
Description: ANGPTL4 antibody (Cat. #18374-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
Reactivity: Human, Mouse
Host: Rabbit
Conjugate: Unconjugated
Isotype: IgG
Vial size: 20ul, 150ul

ANGPTL4 protein structure - 18374-1-AP shown in red.

Submitted references Knockdown of ANGPTL4 inhibits adipogenesis of preadipocyte via autophagy.

Ling M, Qian H, Guo H
In vitro cellular & developmental biology. Animal 2024 Mar;60(3):258-265

Resistant starch intake facilitates weight loss in humans by reshaping the gut microbiota.

Li H, Zhang L, Li J, Wu Q, Qian L, He J, Ni Y, Kovatcheva-Datchary P, Yuan R, Liu S, Shen L, Zhang M, Sheng B, Li P, Kang K, Wu L, Fang Q, Long X, Wang X, Li Y, Ye Y, Ye J, Bao Y, Zhao Y, Xu G, Liu X, Panagiotou G, Xu A, Jia W
Nature metabolism 2024 Mar;6(3):578-597

Renal lipid accumulation and aging linked to tubular cells injury via ANGPTL4.

Wang X, Chang HC, Gu X, Han W, Mao S, Lu L, Jiang S, Ding H, Han S, Qu X, Bao Z
Mechanisms of ageing and development 2024 Jun;219:111932

Egr-1 is a key regulator of the blood-brain barrier damage induced by meningitic Escherichia coli.

Yang R, Wang X, Liu H, Chen J, Tan C, Chen H, Wang X
Cell communication and signaling : CCS 2024 Jan 17;22(1):44

Identification of crucial anoikis-related genes as novel biomarkers and potential therapeutic targets for lung adenocarcinoma via bioinformatic analysis and experimental verification.

Wu J, Zhang Y, You G, Guo W, Wang Y, Li J, Tan R, Fu X, Tang Y, Zan J, Su J
Aging 2024 Feb 9;16(3):2887-2907

Angiopoietin-like 4 Is a Critical Regulator of Fibroblasts during Pulmonary Fibrosis Development.

Saito S, Kitabatake M, Ouji-Sageshima N, Ogawa T, Oda A, Nishimura T, Nishioka T, Fushimi S, Hara A, Shichino S, Kumamoto M, Hontsu S, Kawaguchi T, Ueha S, Sawabata N, Muro S, Matsushima K, Ito T
American journal of respiratory cell and molecular biology 2023 Sep;69(3):328-339

High glucose-induced IL-7/IL-7R upregulation of dermal fibroblasts inhibits angiogenesis in a paracrine way in delayed diabetic wound healing.

Gao R, Zhou P, Li Y, Li Q
Journal of cell communication and signaling 2023 Sep;17(3):1023-1038

Adipocytes promote pancreatic cancer migration and invasion through fatty acid metabolic reprogramming.

Cai Z, Li Y, Ma M, Wang L, Wang H, Liu M, Jiang C
Oncology reports 2023 Jul;50(1)

N-acetylglucosamine-bearing polymers mimicking O-GlcNAc-modified proteins elicit anti-fibrotic activities in myofibroblasts and activated stellate cells.

Ise H, Araki Y, Song I, Akatsuka G
Glycobiology 2023 Jan 8;33(1):17-37

Angiopoietin-like 4 induces head and neck squamous cell carcinoma cell migration through the NRP1/ABL1/PXN pathway.

Hefni E, Menon D, Ma T, Asiedu EB, Sultan A, Meiller T, Schneider A, Sodhi A, Montaner S
Cellular signalling 2023 Aug;108:110697

ANGPTL4 regulates the osteogenic differentiation of periodontal ligament stem cells.

Xu L, Wang C, Li Y, Wang Y, Fu B, Yang G
Functional & integrative genomics 2022 Oct;22(5):769-781

Angiopoietin-like 4 promotes glucose metabolism by regulating glucose transporter expression in colorectal cancer.

Mizuno S, Seishima R, Yamasaki J, Hattori K, Ogiri M, Matsui S, Shigeta K, Okabayashi K, Nagano O, Li L, Kitagawa Y
Journal of cancer research and clinical oncology 2022 Jun;148(6):1351-1361

ManNAc protects against podocyte pyroptosis via inhibiting mitochondrial damage and ROS/NLRP3 signaling pathway in diabetic kidney injury model.

Gao Y, Ma Y, Xie D, Jiang H
International immunopharmacology 2022 Jun;107:108711

Integrative Proteomic and Phosphoproteomic Analyses of Hypoxia-Treated Pulmonary Artery Smooth Muscle Cells.

Luo A, Hao R, Zhou X, Jia Y, Tang H
Proteomes 2022 Jun 28;10(3)

Allobaculum Involves in the Modulation of Intestinal ANGPTLT4 Expression in Mice Treated by High-Fat Diet.

Zheng Z, Lyu W, Ren Y, Li X, Zhao S, Yang H, Xiao Y
Frontiers in nutrition 2021;8:690138

Expression of ANGPTL4 in Nucleus Pulposus Tissues Is Associated with Intervertebral Disc Degeneration.

Liu FJ, Xie LY, Li HZ, Cao SN, Chen YZ, Bin-Shi, Wang DD
Disease markers 2021;2021:3532716

Baicalein Enhances the Effect of Acarbose on the Improvement of Nonalcoholic Fatty Liver Disease Associated with Prediabetes via the Inhibition of De Novo Lipogenesis.

Xing Y, Ren X, Li X, Sui L, Shi X, Sun Y, Quan C, Xiu Z, Dong Y
Journal of agricultural and food chemistry 2021 Sep 1;69(34):9822-9836

Banxia Baizhu Tianma decoction attenuates obesity-related hypertension.

Jiang YH, Zhang P, Tao Y, Liu Y, Cao G, Zhou L, Yang CH
Journal of ethnopharmacology 2021 Feb 10;266:113453

Decreased ANGPTL4 impairs endometrial angiogenesis during peri-implantation period in patients with recurrent implantation failure.

Li M, Hu J, Yao L, Gao M
Journal of cellular and molecular medicine 2020 Sep;24(18):10730-10743

Angiopoietin-Like Protein 4 (ANGPTL4) Induces Retinal Pigment Epithelial Barrier Breakdown by Activating Signal Transducer and Activator of Transcription 3 (STAT3): Evidence from ARPE-19 Cells Under Hypoxic Condition and Diabetic Rats.

Yang X, Cao J, Du Y, Gong Q, Cheng Y, Su G
Medical science monitor : international medical journal of experimental and clinical research 2019 Sep 8;25:6742-6754

LncRNA HAND2-AS1 promotes liver cancer stem cell self-renewal via BMP signaling.

Wang Y, Zhu P, Luo J, Wang J, Liu Z, Wu W, Du Y, Ye B, Wang D, He L, Ren W, Wang J, Sun X, Chen R, Tian Y, Fan Z
The EMBO journal 2019 Sep 2;38(17):e101110

Angiopoietin-like 4 binds neuropilins and cooperates with VEGF to induce diabetic macular edema.

Sodhi A, Ma T, Menon D, Deshpande M, Jee K, Dinabandhu A, Vancel J, Lu D, Montaner S
The Journal of clinical investigation 2019 Nov 1;129(11):4593-4608

The long non-coding RNA PVT1 represses ANGPTL4 transcription through binding with EZH2 in trophoblast cell.

Xu Y, Lian Y, Zhang Y, Huang S, Zuo Q, Yang N, Chen Y, Wu D, Sun L
Journal of cellular and molecular medicine 2018 Feb;22(2):1272-1282

ANGPTL4 promotes the progression of cutaneous melanoma to brain metastasis.

Izraely S, Ben-Menachem S, Sagi-Assif O, Meshel T, Marzese DM, Ohe S, Zubrilov I, Pasmanik-Chor M, Hoon DSB, Witz IP
Oncotarget 2017 Sep 29;8(44):75778-75796

Hypoxia-induced angiopoietin-like protein 4 as a clinical biomarker and treatment target for human prostate cancer.

Hata S, Nomura T, Iwasaki K, Sato R, Yamasaki M, Sato F, Mimata H
Oncology reports 2017 Jul;38(1):120-128

ANGPTL4-αvβ3 interaction counteracts hypoxia-induced vascular permeability by modulating Src signalling downstream of vascular endothelial growth factor receptor 2.

Gomez Perdiguero E, Liabotis-Fontugne A, Durand M, Faye C, Ricard-Blum S, Simonutti M, Augustin S, Robb BM, Paques M, Valenzuela DM, Murphy AJ, Yancopoulos GD, Thurston G, Galaup A, Monnot C, Germain S
The Journal of pathology 2016 Dec;240(4):461-471

An integrated genomic approach identifies persistent tumor suppressive effects of transforming growth factor-β in human breast cancer.

Sato M, Kadota M, Tang B, Yang HH, Yang YA, Shan M, Weng J, Welsh MA, Flanders KC, Nagano Y, Michalowski AM, Clifford RJ, Lee MP, Wakefield LM
Breast cancer research : BCR 2014 Jun 2;16(3):R57

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Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: HEK-293 cells were subjected to SDS PAGE followed by western blot with 18374-1-AP(ANGPTL4 antibody) at dilution of 1:1000
Sample type: cell line

Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: The ANGPTL4 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human ANGPTL4. This antibody recognizes human, mouse antigen. The ANGPTL4 antibody has been validated for the following applications: ELISA, WB, IHC, IF analysis.
Appendix: 18374-1-AP.pdf

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