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- Antibody Data
- Antigen structure
- References [5]
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- Product number
- BAF3485 - Provider product page
- Provider
- R&D Systems
- Product name
- Human/Primate Angiopoietin-like Protein 4/ANGPTL4 Biotinylated Antibody
- Antibody type
- Polyclonal
- Description
- Antigen Affinity-purified. Detects human ANGPTL4 in ELISAs and Western blots. In sandwich immunoassays, less than 0.2% cross-reactivity with recombinant human (rh) ANGPTL3, rhAngiopoietin-1, -2, -3, and -4 is observed.In Western blots, approximately 1% cross-reactivity with rhANGPLT4 N-terminal Fragment is observed.
- Reactivity
- Human, Simian
- Host
- Goat
- Conjugate
- Biotin
- Antigen sequence
Q9BY76- Isotype
- IgG
- Vial size
- 50 ug
- Concentration
- LYOPH
- Storage
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Submitted references Regulation of angiopoietin-like 4 and lipoprotein lipase in human adipose tissue.
Plasma angiopoietin-like 4 is related to phospholipid transfer protein activity in diabetic and non-diabetic subjects: role of enhanced low grade inflammation.
Effect of diet-induced weight loss on angiopoietin-like protein 4 and adipose tissue lipid metabolism in overweight and obese humans.
Short-chain fatty acids stimulate angiopoietin-like 4 synthesis in human colon adenocarcinoma cells by activating peroxisome proliferator-activated receptor γ.
Caloric restriction and exercise increase plasma ANGPTL4 levels in humans via elevated free fatty acids.
Dijk W, Schutte S, Aarts EO, Janssen IMC, Afman L, Kersten S
Journal of clinical lipidology 2018 May - Jun;12(3):773-783
Journal of clinical lipidology 2018 May - Jun;12(3):773-783
Plasma angiopoietin-like 4 is related to phospholipid transfer protein activity in diabetic and non-diabetic subjects: role of enhanced low grade inflammation.
Gruppen EG, Kersten S, Dullaart RPF
Lipids in health and disease 2018 Mar 27;17(1):60
Lipids in health and disease 2018 Mar 27;17(1):60
Effect of diet-induced weight loss on angiopoietin-like protein 4 and adipose tissue lipid metabolism in overweight and obese humans.
van der Kolk BW, Vink RG, Jocken JWE, Roumans NJT, Goossens GH, Mariman ECM, van Baak MA, Blaak EE
Physiological reports 2018 Jul;6(13):e13735
Physiological reports 2018 Jul;6(13):e13735
Short-chain fatty acids stimulate angiopoietin-like 4 synthesis in human colon adenocarcinoma cells by activating peroxisome proliferator-activated receptor γ.
Alex S, Lange K, Amolo T, Grinstead JS, Haakonsson AK, Szalowska E, Koppen A, Mudde K, Haenen D, Al-Lahham S, Roelofsen H, Houtman R, van der Burg B, Mandrup S, Bonvin AM, Kalkhoven E, Müller M, Hooiveld GJ, Kersten S
Molecular and cellular biology 2013 Apr;33(7):1303-16
Molecular and cellular biology 2013 Apr;33(7):1303-16
Caloric restriction and exercise increase plasma ANGPTL4 levels in humans via elevated free fatty acids.
Kersten S, Lichtenstein L, Steenbergen E, Mudde K, Hendriks HF, Hesselink MK, Schrauwen P, Müller M
Arteriosclerosis, thrombosis, and vascular biology 2009 Jun;29(6):969-74
Arteriosclerosis, thrombosis, and vascular biology 2009 Jun;29(6):969-74
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