66591-1-Ig

antibody from Proteintech Group

Targeting: FASN FAS, SDR27X1

Western blot (Data presented on provider website)

ELISA (Data presented on provider website)

Immunocytochemistry (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

66591-1-Ig

Provider

Proteintech Group

Product name

FASN antibody

Antibody type

Monoclonal

Description

FASN antibody (Cat. #66591-1-Ig) is a mouse monoclonal antibody that shows reactivity with Human and has been validated for the following applications: IF, IHC, WB, ELISA.

Reactivity

Human

Host

Mouse

Conjugate

Unconjugated

Isotype

IgG

Antibody clone number

1B6E4

Vial size

20ul, 150ul

References

Submitted references

Let-7a-5p abrogates progression of papillary thyroid carcinoma cells by decreasing nuclear receptor subfamily 6 group a member 1-mediated lipogenesis.

Zhao T, Sun J, Lu X, Liu L, Chen L, Zhao W, Zhou B
Journal of biochemical and molecular toxicology 2024 Jan;38(1):e23572

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TC2N inhibits distant metastasis and stemness of breast cancer via blocking fatty acid synthesis.

Hao XL, Lv YF, Li DF, Bai FH, Gong J, Pan GQ, Su LX, Wang YL, Fu WL, Liu B, Huang L, Yan D, Tan QL, Liu JY, Guo QN
Journal of translational medicine 2024 Jan 2;22(1):6

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PEDV inhibits HNRNPA3 expression by miR-218-5p to enhance cellular lipid accumulation and promote viral replication.

Shi X, Zhang Q, Yang N, Wang Q, Zhang Y, Xu X
mBio 2024 Feb 14;15(2):e0319723

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Role of Gltp in Maturation of Oligodendrocytes Under the Regulation of Nkx2.2.

Zhang C, Chen Z, Zhang D, Wang X, Qiu M, Tan Z
Molecular neurobiology 2023 Sep;60(9):4897-4908

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Ubiquitin specific peptidase 38 promotes the progression of gastric cancer through upregulation of fatty acid synthase.

Zheng Z, Shang Y, Xu R, Yan X, Wang X, Cai J, Bai Z, Liu X, Yin J, Zhang J, Zhang Z
American journal of cancer research 2022;12(6):2686-2696

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CRISPR Cas9-mediated ablation of pyruvate carboxylase gene in colon cancer cell line HT-29 inhibits growth and migration, induces apoptosis and increases sensitivity to 5-fluorouracil and glutaminase inhibitor.

Ngamkham J, Siritutsoontorn S, Saisomboon S, Vaeteewoottacharn K, Jitrapakdee S
Frontiers in oncology 2022;12:966089

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Derepression of the USP22-FASN axis by p53 loss under oxidative stress drives lipogenesis and tumorigenesis.

Han Z, Liu M, Xie Y, Zeng K, Zhan Z, Chen Y, Wang L, Chen X, Luo Y, Zeng Y, Zhan H, Lin Y, Zhang K, Zhu X, Liu S, Luo X, Zhou A
Cell death discovery 2022 Nov 4;8(1):445

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SIRT1/mTOR pathway-mediated autophagy dysregulation promotes Pb-induced hepatic lipid accumulation in HepG2 cells.

Zhao Y, Mao A, Zhang R, Guan S, Lu J
Environmental toxicology 2022 Mar;37(3):549-563

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Herb-sourced emodin inhibits angiogenesis of breast cancer by targeting VEGFA transcription.

Zou G, Zhang X, Wang L, Li X, Xie T, Zhao J, Yan J, Wang L, Ye H, Jiao S, Xiang R, Shi Y
Theranostics 2020;10(15):6839-6853

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OGDHL silencing promotes hepatocellular carcinoma by reprogramming glutamine metabolism.

Dai W, Xu L, Yu X, Zhang G, Guo H, Liu H, Song G, Weng S, Dong L, Zhu J, Liu T, Guo C, Shen X
Journal of hepatology 2020 May;72(5):909-923

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Feeding induces cholesterol biosynthesis via the mTORC1-USP20-HMGCR axis.

Lu XY, Shi XJ, Hu A, Wang JQ, Ding Y, Jiang W, Sun M, Zhao X, Luo J, Qi W, Song BL
Nature 2020 Dec;588(7838):479-484