MAB1905

antibody from Abnova Corporation

Targeting: ITK EMT, LYK, PSCTK2

Western blot (Recommended by provider)

Immunoprecipitation (Recommended by provider)

Antibody Data

Product number

MAB1905

Provider

Abnova Corporation

Proper citation

Abnova Corporation Cat#MAB1905, RRID:AB_1679200

Product name

Itk monoclonal antibody, clone 2F12

Antibody type

Monoclonal

Antigen

Recombinant protein corresponding to N-terminus of mouse Itk.

Description

Mouse monoclonal antibody raised against partial recombinant Itk.

Reactivity

Human, Mouse

Host

Mouse

Isotype

IgG

Vial size

100 μg

Storage

Store at -20°C.Aliquot to avoid repeated freezing and thawing.

References

Submitted references

Biochemical interactions integrating Itk with the T cell receptor-initiated signaling cascade.

Bunnell SC, Diehn M, Yaffe MB, Findell PR, Cantley LC, Berg LJ
The Journal of biological chemistry 2000 Jan 21;275(3):2219-30

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Regulated association between the tyrosine kinase Emt/Itk/Tsk and phospholipase-C gamma 1 in human T lymphocytes.

Perez-Villar JJ, Kanner SB
Journal of immunology (Baltimore, Md. : 1950) 1999 Dec 15;163(12):6435-41

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T cell receptor-initiated calcium release is uncoupled from capacitative calcium entry in Itk-deficient T cells.

Liu KQ, Bunnell SC, Gurniak CB, Berg LJ
The Journal of experimental medicine 1998 May 18;187(10):1721-7