Antibody data
- Antibody Data
- Antigen structure
- References [42]
- Comments [0]
- Validations [0]
Submit
Validation data
Reference
Comment
Report error
- Product number
- 66406-1-Ig - Provider product page
- Provider
- Proteintech Group
- Product name
- CD80/B7-1 antibody
- Antibody type
- Monoclonal
- Description
- CD80/B7-1 antibody (Cat. #66406-1-Ig) is a mouse monoclonal antibody that shows reactivity with human, mouse, pig and has been validated for the following applications: IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Porcine
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- 1E2F10
- Vial size
- 20ul, 150ul
Submitted references Vimentin, inversely correlating with infiltration of CD8 + T lymphocytes, promotes nuclear translocation of PD-L1 in esophageal squamous cell carcinoma.
Tumor associated antigens combined with carbon dots for inducing durable antitumor immunity.
Botulinum toxin type A inhibits M1 macrophage polarization by deactivation of JAK2/STAT1 and IκB/NFκB pathway and contributes to scar alleviation in aseptic skin wound healing.
Podocyte SIRPα reduction aggravates lupus nephritis via promoting T cell inflammatory responses.
Co-targeting CD47 and VEGF elicited potent anti-tumor effects in gastric cancer.
TPX2 influences the regulation of macrophage polarization via the NF-κB pathway in lung adenocarcinoma.
Prednisone combined with Dihydroartemisinin attenuates systemic lupus erythematosus by regulating M1/M2 balance through the MAPK signaling pathway.
Distinctive multicellular immunosuppressive hubs confer different intervention strategies for left- and right-sided colon cancers.
Corosolic acid attenuates platelet-derived growth factor signaling in macrophages and smooth muscle cells of pulmonary arterial hypertension.
Myeloid-derived growth factor ameliorates dextran sodium sulfate-induced colitis by regulating macrophage polarization.
Noninvasive Transdermal Administration of mRNA Vaccines Encoding Multivalent Neoantigens Effectively Inhibits Melanoma Growth.
Comprehensive molecular characterization of long-term glioblastoma survivors.
Hinokitiol as a modulator of TLR4 signaling and apoptotic pathways in atopic dermatitis.
NIR-Actuated Targeted Janus Nanomotors Remodel Immunosuppressive Tumor Microenvironment for Augmented Cancer Immunotherapy.
Metal-polyphenol networks-modified tantalum plate for craniomaxillofacial reconstruction.
Blockade of C5a receptor unleashes tumor-associated macrophage antitumor response and enhances CXCL9-dependent CD8(+) T cell activity.
Neutrophil peptide 1 accelerates the clearance of degenerative axons during Wallerian degeneration by activating macrophages after peripheral nerve crush injury.
Near Infrared Responsive Gold Nanorods Attenuate Osteoarthritis Progression by Targeting TRPV1.
Activation of GABA receptor attenuates intestinal inflammation by modulating enteric glial cells function through inhibiting NF-κB pathway.
In vivo transfection of cytokine genes into tumor cells using a synthetic vehicle promotes antitumor immune responses in a visceral tumor model.
The involvement of Th1 cell differentiation in the anti-tumor effect of purified polysaccharide from Sanghuangporus vaninii in colorectal cancer via multi-omics analysis.
CTLA4 depletes T cell endogenous and trogocytosed B7 ligands via cis-endocytosis.
Macrophages and derived-TNF-α promote lipopolysaccharide-induced upregulation of endogenous β-glucuronidase in the epithelial cells of the bile duct: A possible facilitator of hepatolithiasis formation.
Five EMT-related genes signature predicts overall survival and immune environment in microsatellite instability-high gastric cancer.
Special issue "The advance of solid tumor research in China": Multi-omics analysis based on 1311 clear cell renal cell carcinoma samples identifies a glycolysis signature associated with prognosis and treatment response.
T cell-mediated targeted delivery of tadalafil regulates immunosuppression and polyamine metabolism to overcome immune checkpoint blockade resistance in hepatocellular carcinoma.
Converting bacteria into autologous tumor vaccine via surface biomineralization of calcium carbonate for enhanced immunotherapy.
TM9SF4 Is a Crucial Regulator of Inflammation and ER Stress in Inflammatory Bowel Disease.
Effect of Platycodon grandiflorus Polysaccharide on M1 Polarization Induced by Autophagy Degradation of SOCS1/2 Proteins in 3D4/21 Cells.
N-acetylcysteine attenuates atherosclerosis progression in aging LDL receptor deficient mice with preserved M2 macrophages and increased CD146.
Surface Coating of Pulmonary siRNA Delivery Vectors Enabling Mucus Penetration, Cell Targeting, and Intracellular Radical Scavenging for Enhanced Acute Lung Injury Therapy.
Effect of B7-H4 downregulation induced by Toxoplasma gondii infection on dysfunction of decidual macrophages contributes to adverse pregnancy outcomes.
ILT4 inhibition prevents TAM- and dysfunctional T cell-mediated immunosuppression and enhances the efficacy of anti-PD-L1 therapy in NSCLC with EGFR activation.
Injectable shear-thinning polylysine hydrogels for localized immunotherapy of gastric cancer through repolarization of tumor-associated macrophages.
TRPV1 alleviates osteoarthritis by inhibiting M1 macrophage polarization via Ca(2+)/CaMKII/Nrf2 signaling pathway.
Comprehensive analysis of prognostic immune-related genes and drug sensitivity in cervical cancer.
Mutual antagonism between indoleamine 2,3-dioxygenase 1 and nuclear factor E2-related factor 2 regulates the maturation status of DCs in liver fibrosis.
The Overexpression of CD80 and ISG15 Are Associated with the Progression and Metastasis of Breast Cancer by a Meta-Analysis Integrating Three Microarray Datasets.
A significant role of transcription factors E2F in inflammation and tumorigenesis of nasopharyngeal carcinoma.
CCL8 enhances sensitivity of cutaneous squamous cell carcinoma to photodynamic therapy by recruiting M1 macrophages.
The LncRNA MALAT1 regulates CD80 transcription via the NF-κB signaling pathway in the A549 cell line.
Knockdown of LncRNA MALAT1 contributes to cell apoptosis via regulating NF-κB/CD80 axis in neonatal respiratory distress syndrome.
Liang Y, He S, Liu Q, Liu T, Tan Y, Peng T, Huang C, Lu X, Zheng S
Biochimica et biophysica acta. Molecular cell research 2024 Oct;1871(7):119781
Biochimica et biophysica acta. Molecular cell research 2024 Oct;1871(7):119781
Tumor associated antigens combined with carbon dots for inducing durable antitumor immunity.
Liu H, Zhang T, Zheng M, Xie Z
Journal of colloid and interface science 2024 Nov;673:594-606
Journal of colloid and interface science 2024 Nov;673:594-606
Botulinum toxin type A inhibits M1 macrophage polarization by deactivation of JAK2/STAT1 and IκB/NFκB pathway and contributes to scar alleviation in aseptic skin wound healing.
Zou YP, Shan XF, Qiu JX, Wang LN, Xiang RL, Cai ZG
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 May;174:116468
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 May;174:116468
Podocyte SIRPα reduction aggravates lupus nephritis via promoting T cell inflammatory responses.
Qian B, Lu R, Mao S, Chen Y, Yang M, Zhang W, Zhang M, Zhu D, Liu Z, Zen K, Li L
Cell reports 2024 May 28;43(5):114249
Cell reports 2024 May 28;43(5):114249
Co-targeting CD47 and VEGF elicited potent anti-tumor effects in gastric cancer.
Zhang K, Xu Y, Chang X, Xu C, Xue W, Ding D, Nie M, Cai H, Xu J, Zhan L, Han J, Cai T, Ju D, Feng L, Zhang X, Yin K
Cancer immunology, immunotherapy : CII 2024 Mar 27;73(4):75
Cancer immunology, immunotherapy : CII 2024 Mar 27;73(4):75
TPX2 influences the regulation of macrophage polarization via the NF-κB pathway in lung adenocarcinoma.
Wang L, Zhang H, Li Y, Li L
Life sciences 2024 Mar 1;340:122437
Life sciences 2024 Mar 1;340:122437
Prednisone combined with Dihydroartemisinin attenuates systemic lupus erythematosus by regulating M1/M2 balance through the MAPK signaling pathway.
Chen Y, Tao T, Liang Z, Chen X, Xu Y, Zhang T, Zhou D
Molecular immunology 2024 Jun;170:144-155
Molecular immunology 2024 Jun;170:144-155
Distinctive multicellular immunosuppressive hubs confer different intervention strategies for left- and right-sided colon cancers.
Liu B, Li S, Cheng Y, Song P, Xu M, Li Z, Shao W, Xin J, Fu Z, Gu D, Du M, Zhang Z, Wang M
Cell reports. Medicine 2024 Jun 18;5(6):101589
Cell reports. Medicine 2024 Jun 18;5(6):101589
Corosolic acid attenuates platelet-derived growth factor signaling in macrophages and smooth muscle cells of pulmonary arterial hypertension.
Yamamura A, Fujiwara M, Kawade A, Amano T, Hossain A, Nayeem MJ, Kondo R, Suzuki Y, Inoue Y, Hayashi H, Suzuki S, Sato M, Yamamura H
European journal of pharmacology 2024 Jun 15;973:176564
European journal of pharmacology 2024 Jun 15;973:176564
Myeloid-derived growth factor ameliorates dextran sodium sulfate-induced colitis by regulating macrophage polarization.
Yang Y, Zhao C, Yang Z, Du C, Chang Z, Wen X, Zhang X, Liu Y, Hu L, Gao Z
Journal of molecular medicine (Berlin, Germany) 2024 Jul;102(7):875-886
Journal of molecular medicine (Berlin, Germany) 2024 Jul;102(7):875-886
Noninvasive Transdermal Administration of mRNA Vaccines Encoding Multivalent Neoantigens Effectively Inhibits Melanoma Growth.
Hou Y, Wang Z, Chen Z, Shuai L, Pei Y, Sun B, Jiang Y, Wang H
ACS biomaterials science & engineering 2024 Jul 8;10(7):4587-4600
ACS biomaterials science & engineering 2024 Jul 8;10(7):4587-4600
Comprehensive molecular characterization of long-term glioblastoma survivors.
Xu H, Chen X, Sun Y, Hu X, Zhang X, Wang Y, Tang Q, Zhu Q, Song K, Chen H, Sheng X, Yao Y, Zhuang D, Chen L, Mao Y, Qin Z
Cancer letters 2024 Jul 1;593:216938
Cancer letters 2024 Jul 1;593:216938
Hinokitiol as a modulator of TLR4 signaling and apoptotic pathways in atopic dermatitis.
Tai LR, Chiang YF, Huang KC, Chen HY, Ali M, Hsia SM
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Jan;170:116026
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Jan;170:116026
NIR-Actuated Targeted Janus Nanomotors Remodel Immunosuppressive Tumor Microenvironment for Augmented Cancer Immunotherapy.
Zhou X, Ma E, Zhang Y, Xing Y, Xu W, Chen L, Zhou H, Zhang X, Jiang C, Xu K, Wang H, Zheng S
Advanced healthcare materials 2024 Jan;13(2):e2302272
Advanced healthcare materials 2024 Jan;13(2):e2302272
Metal-polyphenol networks-modified tantalum plate for craniomaxillofacial reconstruction.
Wei Z, Shen Z, Deng H, Kuang T, Wang J, Gu Z
Scientific reports 2024 Jan 10;14(1):1023
Scientific reports 2024 Jan 10;14(1):1023
Blockade of C5a receptor unleashes tumor-associated macrophage antitumor response and enhances CXCL9-dependent CD8(+) T cell activity.
Luan X, Lei T, Fang J, Liu X, Fu H, Li Y, Chu W, Jiang P, Tong C, Qi H, Fu Y
Molecular therapy : the journal of the American Society of Gene Therapy 2024 Feb 7;32(2):469-489
Molecular therapy : the journal of the American Society of Gene Therapy 2024 Feb 7;32(2):469-489
Neutrophil peptide 1 accelerates the clearance of degenerative axons during Wallerian degeneration by activating macrophages after peripheral nerve crush injury.
Kou Y, Yuan Y, Li Q, Xie W, Xu H, Han N
Neural regeneration research 2024 Aug 1;19(8):1822-1827
Neural regeneration research 2024 Aug 1;19(8):1822-1827
Near Infrared Responsive Gold Nanorods Attenuate Osteoarthritis Progression by Targeting TRPV1.
Li W, Lv Z, Wang P, Xie Y, Sun W, Guo H, Jin X, Liu Y, Jiang R, Fei Y, Tan G, Jiang H, Wang X, Liu Z, Wang Z, Xu N, Gong W, Wu R, Shi D
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Apr;11(16):e2307683
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Apr;11(16):e2307683
Activation of GABA receptor attenuates intestinal inflammation by modulating enteric glial cells function through inhibiting NF-κB pathway.
Deng Z, Li D, Yan X, Lan J, Han D, Fan K, Chang J, Ma Y
Life sciences 2023 Sep 15;329:121984
Life sciences 2023 Sep 15;329:121984
In vivo transfection of cytokine genes into tumor cells using a synthetic vehicle promotes antitumor immune responses in a visceral tumor model.
Watanabe S, Takagi A, Yuba E, Kojima C, Dei N, Matsumoto A, Tanikawa J, Kawamura T, De Silva NH, Izawa T, Akazawa T, Kanegi R, Hatoya S, Inaba T, Sugiura K
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Nov;37(11):e23228
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Nov;37(11):e23228
The involvement of Th1 cell differentiation in the anti-tumor effect of purified polysaccharide from Sanghuangporus vaninii in colorectal cancer via multi-omics analysis.
Qu Y, Yang H, Li S, Li L, Li Y, Wang D
International journal of biological macromolecules 2023 May 15;237:123927
International journal of biological macromolecules 2023 May 15;237:123927
CTLA4 depletes T cell endogenous and trogocytosed B7 ligands via cis-endocytosis.
Xu X, Dennett P, Zhang J, Sherrard A, Zhao Y, Masubuchi T, Bui JD, Chen X, Hui E
The Journal of experimental medicine 2023 Jul 3;220(7)
The Journal of experimental medicine 2023 Jul 3;220(7)
Macrophages and derived-TNF-α promote lipopolysaccharide-induced upregulation of endogenous β-glucuronidase in the epithelial cells of the bile duct: A possible facilitator of hepatolithiasis formation.
Yang Y, Wang Y, Wang C, Wu S, Yao D
Clinics and research in hepatology and gastroenterology 2023 Jan;47(1):102062
Clinics and research in hepatology and gastroenterology 2023 Jan;47(1):102062
Five EMT-related genes signature predicts overall survival and immune environment in microsatellite instability-high gastric cancer.
Zhang M, Cao C, Li X, Gu Q, Xu Y, Zhu Z, Xu D, Wei S, Chen H, Yang Y, Gao H, Yu L, Li J
Cancer medicine 2023 Jan;12(2):2075-2088
Cancer medicine 2023 Jan;12(2):2075-2088
Special issue "The advance of solid tumor research in China": Multi-omics analysis based on 1311 clear cell renal cell carcinoma samples identifies a glycolysis signature associated with prognosis and treatment response.
Tian X, Wang Y, Xu W, Tang H, Zhu S, Anwaier A, Liu W, Wang W, Zhu W, Su J, Qu Y, Zhang H, Ye D
International journal of cancer 2023 Jan 1;152(1):66-78
International journal of cancer 2023 Jan 1;152(1):66-78
T cell-mediated targeted delivery of tadalafil regulates immunosuppression and polyamine metabolism to overcome immune checkpoint blockade resistance in hepatocellular carcinoma.
Wang X, Zhang Q, Zhou J, Xiao Z, Liu J, Deng S, Hong X, Huang W, Cai M, Guo Y, Huang J, Wang Y, Lin L, Zhu K
Journal for immunotherapy of cancer 2023 Feb;11(2)
Journal for immunotherapy of cancer 2023 Feb;11(2)
Converting bacteria into autologous tumor vaccine via surface biomineralization of calcium carbonate for enhanced immunotherapy.
Guo L, Ding J, Zhou W
Acta pharmaceutica Sinica. B 2023 Dec;13(12):5074-5090
Acta pharmaceutica Sinica. B 2023 Dec;13(12):5074-5090
TM9SF4 Is a Crucial Regulator of Inflammation and ER Stress in Inflammatory Bowel Disease.
Xie M, Mak JWY, Yu H, Cheng CTY, Chan HCH, Chan TT, Lau LHS, Wong MTL, Ko WH, Jiang L, Yao X
Cellular and molecular gastroenterology and hepatology 2022;14(2):245-270
Cellular and molecular gastroenterology and hepatology 2022;14(2):245-270
Effect of Platycodon grandiflorus Polysaccharide on M1 Polarization Induced by Autophagy Degradation of SOCS1/2 Proteins in 3D4/21 Cells.
Li L, Chen X, Lv M, Cheng Z, Liu F, Wang Y, Zhou A, Liu J, Zhao X
Frontiers in immunology 2022;13:934084
Frontiers in immunology 2022;13:934084
N-acetylcysteine attenuates atherosclerosis progression in aging LDL receptor deficient mice with preserved M2 macrophages and increased CD146.
Zhu Q, Xiao Y, Jiang M, Liu X, Cui Y, Hao H, Flaker GC, Liu Q, Zhou S, Liu Z
Atherosclerosis 2022 Sep;357:41-50
Atherosclerosis 2022 Sep;357:41-50
Surface Coating of Pulmonary siRNA Delivery Vectors Enabling Mucus Penetration, Cell Targeting, and Intracellular Radical Scavenging for Enhanced Acute Lung Injury Therapy.
Zhu J, Guo M, Cui Y, Meng Y, Ding J, Zeng W, Zhou W
ACS applied materials & interfaces 2022 Feb 2;14(4):5090-5100
ACS applied materials & interfaces 2022 Feb 2;14(4):5090-5100
Effect of B7-H4 downregulation induced by Toxoplasma gondii infection on dysfunction of decidual macrophages contributes to adverse pregnancy outcomes.
Cui L, Wang Y, Ren L, Li Z, Jiang Y, Wang C, Liu X, Ren Y, Hu X
Parasites & vectors 2022 Dec 13;15(1):464
Parasites & vectors 2022 Dec 13;15(1):464
ILT4 inhibition prevents TAM- and dysfunctional T cell-mediated immunosuppression and enhances the efficacy of anti-PD-L1 therapy in NSCLC with EGFR activation.
Chen X, Gao A, Zhang F, Yang Z, Wang S, Fang Y, Li J, Wang J, Shi W, Wang L, Zheng Y, Sun Y
Theranostics 2021;11(7):3392-3416
Theranostics 2021;11(7):3392-3416
Injectable shear-thinning polylysine hydrogels for localized immunotherapy of gastric cancer through repolarization of tumor-associated macrophages.
Yang Y, Yang Y, Chen M, Chen J, Wang J, Ma Y, Qian H
Biomaterials science 2021 Sep 28;9(19):6597-6608
Biomaterials science 2021 Sep 28;9(19):6597-6608
TRPV1 alleviates osteoarthritis by inhibiting M1 macrophage polarization via Ca(2+)/CaMKII/Nrf2 signaling pathway.
Lv Z, Xu X, Sun Z, Yang YX, Guo H, Li J, Sun K, Wu R, Xu J, Jiang Q, Ikegawa S, Shi D
Cell death & disease 2021 May 18;12(6):504
Cell death & disease 2021 May 18;12(6):504
Comprehensive analysis of prognostic immune-related genes and drug sensitivity in cervical cancer.
Pi YN, Guo JN, Lou G, Cui BB
Cancer cell international 2021 Dec 1;21(1):639
Cancer cell international 2021 Dec 1;21(1):639
Mutual antagonism between indoleamine 2,3-dioxygenase 1 and nuclear factor E2-related factor 2 regulates the maturation status of DCs in liver fibrosis.
Mo C, Xie S, Zhong W, Zeng T, Huang S, Lai Y, Deng G, Zhou C, Yan W, Chen Y, Huang S, Gao L, Lv Z
Free radical biology & medicine 2020 Nov 20;160:178-190
Free radical biology & medicine 2020 Nov 20;160:178-190
The Overexpression of CD80 and ISG15 Are Associated with the Progression and Metastasis of Breast Cancer by a Meta-Analysis Integrating Three Microarray Datasets.
Li Y, Bai W, Zhang L
Pathology oncology research : POR 2020 Jan;26(1):443-452
Pathology oncology research : POR 2020 Jan;26(1):443-452
A significant role of transcription factors E2F in inflammation and tumorigenesis of nasopharyngeal carcinoma.
Liu P, Zhang X, Li Z, Wei L, Peng Q, Liu C, Wu Y, Yan Q, Ma J
Biochemical and biophysical research communications 2020 Apr 16;524(4):816-824
Biochemical and biophysical research communications 2020 Apr 16;524(4):816-824
CCL8 enhances sensitivity of cutaneous squamous cell carcinoma to photodynamic therapy by recruiting M1 macrophages.
Ji J, Wang P, Zhou Q, Zhu L, Zhang H, Zhang Y, Zheng Z, Bhatta AK, Zhang G, Wang X
Photodiagnosis and photodynamic therapy 2019 Jun;26:235-243
Photodiagnosis and photodynamic therapy 2019 Jun;26:235-243
The LncRNA MALAT1 regulates CD80 transcription via the NF-κB signaling pathway in the A549 cell line.
Juan C, Mao Y, Wang Q, Cao Q, Chen Y, Zhou G
Biochemical and biophysical research communications 2018 Sep 10;503(3):1674-1681
Biochemical and biophysical research communications 2018 Sep 10;503(3):1674-1681
Knockdown of LncRNA MALAT1 contributes to cell apoptosis via regulating NF-κB/CD80 axis in neonatal respiratory distress syndrome.
Juan C, Wang Q, Mao Y, Cao Q, Li S, Qiao C, Zhang D, Zhou G
The international journal of biochemistry & cell biology 2018 Nov;104:138-148
The international journal of biochemistry & cell biology 2018 Nov;104:138-148
No comments: Submit comment
No validations: Submit validation data