67211-1-Ig

antibody from Proteintech Group

Targeting: TBK1 NAK

Western blot (Data presented on provider website)

ELISA (Data presented on provider website)

Antibody Data

Product number

67211-1-Ig

Provider

Proteintech Group

Product name

TBK1 antibody

Antibody type

Monoclonal

Description

TBK1 antibody (Cat. #67211-1-Ig) is a mouse monoclonal antibody that shows reactivity with Human, Mouse, Rat and has been validated for the following applications: WB,ELISA.

Reactivity

Human, Mouse, Rat

Host

Mouse

Conjugate

Unconjugated

Isotype

IgG

Antibody clone number

2D7B1

Vial size

20ul, 150ul

References

Submitted references

Porcine deltacoronavirus nsp5 antagonizes type I interferon signaling by cleaving IFIT3.

Huang H, Lei X, Zhao C, Qin Y, Li Y, Zhang X, Li C, Lan T, Zhao B, Sun W, Lu H, Jin N
Journal of virology 2024 Feb 20;98(2):e0168223

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Neutrophil Extracellular Traps Regulate Surgical Brain Injury by Activating the cGAS-STING Pathway.

Li B, Xu L, Wang Z, Shi Q, Cui Y, Fan W, Wu Q, Tong X, Yan H
Cellular and molecular neurobiology 2024 Apr 18;44(1):36

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FEN1 inhibitor SC13 promotes CAR-T cells infiltration into solid tumours through cGAS-STING signalling pathway.

Dong Y, Wang Y, Yin X, Zhu H, Liu L, Zhang M, Chen J, Wang A, Huang T, Hu J, Liang J, Guo Z, He L
Immunology 2023 Nov;170(3):388-400

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TRAF7 negatively regulates the RLR signaling pathway by facilitating the K48-linked ubiquitination of TBK1.

Huang JP, Yang YX, Chen T, Wang DD, Li J, Xu LG
Virologica Sinica 2023 Jun;38(3):419-428

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STING deficiency protects against wasp venom-induced acute kidney injury.

Lv Y, Lu L, Yu F, Gao Z, Yuan H, Hu F
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2023 Jul;72(7):1427-1440

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Functional Characterization of a Familial ALS-Associated Missense TBK1 (p-Arg573Gly) Mutation in Patient-Derived Lymphoblasts.

Porras G, Ruiz S, Maestro I, Borrego-Hernández D, Redondo AG, Martínez A, Martín-Requero Á
International journal of molecular sciences 2023 Feb 2;24(3)

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Metformin promotes cGAS/STING signaling pathway activation by blocking AKT phosphorylation in gastric cancer.

Shen Q, Yang L, Li C, Wang T, Lv J, Liu W, Lin Y, Yin Y, Tao K
Heliyon 2023 Aug;9(8):e18954

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Naringin protects against inflammation and apoptosis induced by intestinal ischemia-reperfusion injury through deactivation of cGAS-STING signaling pathway.

Gu L, Wang F, Wang Y, Sun D, Sun Y, Tian T, Meng Q, Yin L, Xu L, Lu X, Peng J, Lin Y, Sun P
Phytotherapy research : PTR 2023 Aug;37(8):3495-3507

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Development of Orally Bioavailable Amidobenzimidazole Analogues Targeting Stimulator of Interferon Gene (STING) Receptor.

Chen NN, Zhang H, Zhu QS, Zeng T, Dai W, Zhou YL, Xin GF, Wu BD, Gong SJ, Jiang ZY, You QD, Xu XL
Journal of medicinal chemistry 2023 Apr 27;66(8):5584-5610

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Nuclear translocation of cGAS orchestrates VEGF-A-mediated angiogenesis.

Luo J, Lu C, Chen Y, Wu X, Zhu C, Cui W, Yu S, Li N, Pan Y, Zhao W, Yang Q, Yang X
Cell reports 2023 Apr 25;42(4):112328

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Macrophage SCAP Contributes to Metaflammation and Lean NAFLD by Activating STING-NF-κB Signaling Pathway.

Huang X, Yao Y, Hou X, Wei L, Rao Y, Su Y, Zheng G, Ruan XZ, Li D, Chen Y
Cellular and molecular gastroenterology and hepatology 2022;14(1):1-26

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Identification of highly specific antibodies for Serine/threonine-protein kinase TBK1 for use in immunoblot, immunoprecipitation and immunofluorescence.

Alshafie W, Fotouhi M, Shlaifer I, Ayoubi R, Edwards AM, Durcan TM, McPherson PS, Laflamme C
F1000Research 2022;11:977

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Swine Acute Diarrhea Syndrome Coronavirus Nucleocapsid Protein Antagonizes Interferon-β Production via Blocking the Interaction Between TRAF3 and TBK1.

Zhou Z, Sun Y, Xu J, Tang X, Zhou L, Li Q, Lan T, Ma J
Frontiers in immunology 2021;12:573078

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IFI16 promotes cervical cancer progression by upregulating PD-L1 in immunomicroenvironment through STING-TBK1-NF-kB pathway.

Cai H, Yan L, Liu N, Xu M, Cai H
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Mar;123:109790