Antibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Immunocytochemistry [1]
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Validation data
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- Product number
- ABIN500308 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-TANK-Binding Kinase 1 (TBK1) (C-Term) antibody
- Antibody type
- Polyclonal
- Antigen
- Peptide from C-term of human NAK / TBK1 (Cat. No. 2351P)
- Description
- Peptide affinity chromatography
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Epitope
- C-Term
- Isotype
- IgG
- Vial size
- 0.1 mg
- Storage
- Store at 2 - 8°C for up to one month or (in aliquots) at -20°C for longer.
- Handling
- Avoid repeated freezing and thawing.
Submitted references Endocrine orchestration of cardiovascular, gastrointestinal and hypothalamic control.
The intracellular form of notch blocks transforming growth factor beta-mediated growth arrest in Mv1Lu epithelial cells.
Deficiency of T2K leads to apoptotic liver degeneration and impaired NF-kappaB-dependent gene transcription.
NAK is an IkappaB kinase-activating kinase.
NF-kappaB activation by a signaling complex containing TRAF2, TANK and TBK1, a novel IKK-related kinase.
Angelone T, Quintieri AM, Amodio N, Cerra MC
Current medicinal chemistry 2011;18(32):4976-86
Current medicinal chemistry 2011;18(32):4976-86
The intracellular form of notch blocks transforming growth factor beta-mediated growth arrest in Mv1Lu epithelial cells.
Rao P, Kadesch T
Molecular and cellular biology 2003 Sep;23(18):6694-701
Molecular and cellular biology 2003 Sep;23(18):6694-701
Deficiency of T2K leads to apoptotic liver degeneration and impaired NF-kappaB-dependent gene transcription.
Bonnard M, Mirtsos C, Suzuki S, Graham K, Huang J, Ng M, ItiƩ A, Wakeham A, Shahinian A, Henzel WJ, Elia AJ, Shillinglaw W, Mak TW, Cao Z, Yeh WC
The EMBO journal 2000 Sep 15;19(18):4976-85
The EMBO journal 2000 Sep 15;19(18):4976-85
NAK is an IkappaB kinase-activating kinase.
Tojima Y, Fujimoto A, Delhase M, Chen Y, Hatakeyama S, Nakayama K, Kaneko Y, Nimura Y, Motoyama N, Ikeda K, Karin M, Nakanishi M
Nature 2000 Apr 13;404(6779):778-82
Nature 2000 Apr 13;404(6779):778-82
NF-kappaB activation by a signaling complex containing TRAF2, TANK and TBK1, a novel IKK-related kinase.
Pomerantz JL, Baltimore D
The EMBO journal 1999 Dec 1;18(23):6694-704
The EMBO journal 1999 Dec 1;18(23):6694-704
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Immunocytochemistry of NAK in MOLT4 cells with AP30575PU-N at 10 ?g/ml.