Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- HPA014658 - Provider product page
- Provider
- Atlas Antibodies
- Proper citation
- Atlas Antibodies Cat#HPA014658, RRID:AB_1850428
- Product name
- Anti-ARHGEF11
- Antibody type
- Polyclonal
- Description
- Polyclonal Antibody against Human ARHGEF11, Gene description: Rho guanine nucleotide exchange factor (GEF) 11, Alternative Gene Names: GTRAP48, KIAA0380, PDZ-RHOGEF, Validated applications: IHC, WB, Uniprot ID: O15085, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µl
- Concentration
- 0.3 mg/ml
- Storage
- Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Handling
- The antibody solution should be gently mixed before use.
Submitted references Oncogenic Gαq activates RhoJ through PDZ-RhoGEF
Gα(s) directly drives PDZ-RhoGEF signaling to Cdc42.
Protumoral bone marrow-derived cells migrate via Gβγ-dependent signaling pathways and exhibit a complex repertoire of RhoGEFs
Cervantes-Villagrana R, Color-Aparicio V, Castillo-Kauil A, García-Jiménez I, Beltrán-Navarro Y, Reyes-Cruz G, Vázquez-Prado J
International Journal of Molecular Sciences 2023;24(21):15734
International Journal of Molecular Sciences 2023;24(21):15734
Gα(s) directly drives PDZ-RhoGEF signaling to Cdc42.
Castillo-Kauil A, García-Jiménez I, Cervantes-Villagrana RD, Adame-García SR, Beltrán-Navarro YM, Gutkind JS, Reyes-Cruz G, Vázquez-Prado J
The Journal of biological chemistry 2020 Dec 11;295(50):16920-16928
The Journal of biological chemistry 2020 Dec 11;295(50):16920-16928
Protumoral bone marrow-derived cells migrate via Gβγ-dependent signaling pathways and exhibit a complex repertoire of RhoGEFs
Cervantes-Villagrana R, Color-Aparicio V, Reyes-Cruz G, Vázquez-Prado J
Journal of Cell Communication and Signaling 2019;13(2):179-191
Journal of Cell Communication and Signaling 2019;13(2):179-191
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Enhanced validation
- Submitted by
- Atlas Antibodies (provider)
- Enhanced method
- Recombinant expression validation
- Main image
- Experimental details
- Western blot analysis in control (vector only transfected HEK293T lysate) and ARHGEF11 over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa) in mammalian HEK293T cells, LY404959).
- Sample type
- Human
- Protocol
- Protocol