TBX10

This gene encodes a member of the T-box family of transcription factors. These transcription factors share a DNA-binding domain called the T-box, and play a role in several developmental processes including early embryonic cell fate and organogenesis. The encoded protein is a member of the T-box 1 subfamily. Mutations in this gene are thought to be a cause of isolated cleft lip with or without cleft palate. [provided by RefSeq, Nov 2010]

Description

T-box transcription factor 10

Tissue specificity

Tissue enriched (intestine)

Subcell location

Nucleoplasm, Cytosol

Predicted location

Intracellular

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins
Transcription factors

Chromosome

11 (67631303 - 67639560)

Ensembl ID

ENSG00000167800  (ver. 103.38)

Orthologs

-

UniProt

O75333

neXtProt

NX_O75333

Human splice variants

Protein structure