67912-1-Ig

antibody from Proteintech Group

Targeting: NR1I2 BXR, ONR1, PAR2, PXR, SXR

Western blot (Data presented on provider website)

ELISA (Data presented on provider website)

Antibody Data

Product number

67912-1-Ig

Provider

Proteintech Group

Product name

PXR antibody

Antibody type

Monoclonal

Description

PXR antibody (Cat. #67912-1-Ig) is a mouse monoclonal antibody that shows reactivity with Human, Mouse, Rat and has been validated for the following applications: WB, ELISA.

Reactivity

Human, Mouse, Rat

Host

Mouse

Conjugate

Unconjugated

Isotype

IgG

Antibody clone number

1G3A7

Vial size

20ul, 150ul

References

Submitted references

Pregnane X Receptor Activation in Liver Macrophages Protects against Endotoxin-Induced Liver Injury.

Zhao T, Zhong G, Wang Y, Cao R, Song S, Li Y, Wan G, Sun H, Huang M, Bi H, Jiang Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 May;11(19):e2308771

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Bacteroides dorei BDX-01 alleviates DSS-induced experimental colitis in mice by regulating intestinal bile salt hydrolase activity and the FXR-NLRP3 signaling pathway.

Sun X, Chen Z, Yu L, Zeng W, Sun B, Fan H, Bai Y
Frontiers in pharmacology 2023;14:1205323

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Metabolic characteristics of voriconazole - Induced liver injury in rats.

Du Q, Teng M, Yang L, Meng C, Qiu Y, Wang C, Chen J, Wang T, Chen S, Luo Y, Sun J, Dong Y
Chemico-biological interactions 2023 Sep 25;383:110693

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Pregnane X receptor activation alleviates renal fibrosis in mice via interacting with p53 and inhibiting the Wnt7a/β-catenin signaling.

Ming WH, Luan ZL, Yao Y, Liu HC, Hu SY, Du CX, Zhang C, Zhao YH, Huang YZ, Sun XW, Qiao RF, Xu H, Guan YF, Zhang XY
Acta pharmacologica Sinica 2023 Oct;44(10):2075-2090

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Resveratrol attenuates efavirenz-induced hepatic steatosis and hypercholesterolemia in mice by inhibiting pregnane X receptor activation and decreasing inflammation.

Miao X, Ye H, Cui X, Guo X, Su F
Nutrition research (New York, N.Y.) 2023 Nov;119:119-131

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Panaxytriol upregulates CYP3A4 expression through the interaction between nuclear regulators and DNA response elements.

Yan J, Gu Q, Meng C, Liu J, Liu F, Xia C
Journal of ethnopharmacology 2023 Jun 28;310:116398

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Type 1 diabetes and diet-induced obesity predispose C57BL/6J mice to PM(2.5)-induced lung injury: a comparative study.

Chen S, Li M, Zhang R, Ye L, Jiang Y, Jiang X, Peng H, Wang Z, Guo Z, Chen L, Zhang R, Niu Y, Aschner M, Li D, Chen W
Particle and fibre toxicology 2023 Apr 17;20(1):10

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Panaxytriol upregulates CYP3A4 expression based on the interaction of PXR, CAR, HSP90α, and RXRα.

Zhang L, Yan J, Liu J, Meng C, Liu F, Xia C
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Jul;101:154097

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CD36 and DGAT2 facilitate the lipid-lowering effect of chitooligosaccharides via fatty acid intake and triglyceride synthesis signaling.

Shen X, Liang X, Ji X, You J, Zhuang X, Song Y, Yin H, Zhao M, Zhao L
Food & function 2021 Sep 20;12(18):8681-8693