Antibody data
- Antibody Data
- Antigen structure
- References [8]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- 15607-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#15607-1-AP, RRID:AB_11182178
- Product name
- PXR antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated PXR antibody (Cat. #15607-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Constitutive Androstane Receptor-Mediated Inhibition of Metformin on Phase II Metabolic Enzyme SULT2A1.
A high-throughput cell-based gaussia luciferase reporter assay for measurement of CYP1A1, CYP2B6, and CYP3A4 induction.
Proteases Activate Pregnancy Neutrophils by a Protease-Activated Receptor 1 Pathway: Epigenetic Implications for Preeclampsia.
Protease Amplification of the Inflammatory Response Induced by Commensal Bacteria: Implications for Racial Disparity in Term and Preterm Birth.
Constitutive androstane receptor weakens the induction of panaxytriol on CYP3A4 by repressing the activation of pregnane X receptor.
Poly(ADP-ribosyl)ated PXR is a critical regulator of acetaminophen-induced hepatotoxicity.
Gancao (Glycyrrhizae Radix) provides the main contribution to Shaoyao-Gancao decoction on enhancements of CYP3A4 and MDR1 expression via pregnane X receptor pathway in vitro.
Retinoic acid induces macrophage cholesterol efflux and inhibits atherosclerotic plaque formation in apoE-deficient mice.
Hu X, Li M, Zhang C, Pang S
International journal of endocrinology 2021;2021:8867218
International journal of endocrinology 2021;2021:8867218
A high-throughput cell-based gaussia luciferase reporter assay for measurement of CYP1A1, CYP2B6, and CYP3A4 induction.
Li H, Wang YG, Ma ZC, Yun-Hang G, Ling S, Teng-Fei C, Guang-Ping Z, Gao Y
Xenobiotica; the fate of foreign compounds in biological systems 2021 Jul;51(7):752-763
Xenobiotica; the fate of foreign compounds in biological systems 2021 Jul;51(7):752-763
Proteases Activate Pregnancy Neutrophils by a Protease-Activated Receptor 1 Pathway: Epigenetic Implications for Preeclampsia.
Walsh SW, Nugent WH, Al Dulaimi M, Washington SL, Dacha P, Strauss JF 3rd
Reproductive sciences (Thousand Oaks, Calif.) 2020 Nov;27(11):2115-2127
Reproductive sciences (Thousand Oaks, Calif.) 2020 Nov;27(11):2115-2127
Protease Amplification of the Inflammatory Response Induced by Commensal Bacteria: Implications for Racial Disparity in Term and Preterm Birth.
Walsh SW, Nugent WH, Alam SMK, Washington SL, Teves M, Jefferson KK, Strauss JF 3rd
Reproductive sciences (Thousand Oaks, Calif.) 2020 Jan;27(1):246-259
Reproductive sciences (Thousand Oaks, Calif.) 2020 Jan;27(1):246-259
Constitutive androstane receptor weakens the induction of panaxytriol on CYP3A4 by repressing the activation of pregnane X receptor.
Hu Q, Yao N, Wu J, Liu M, Liu F, Zhang H, Xiong Y, Xia C
Biochemical pharmacology 2019 Jan;159:32-39
Biochemical pharmacology 2019 Jan;159:32-39
Poly(ADP-ribosyl)ated PXR is a critical regulator of acetaminophen-induced hepatotoxicity.
Wang C, Xu W, Zhang Y, Huang D, Huang K
Cell death & disease 2018 Jul 26;9(8):819
Cell death & disease 2018 Jul 26;9(8):819
Gancao (Glycyrrhizae Radix) provides the main contribution to Shaoyao-Gancao decoction on enhancements of CYP3A4 and MDR1 expression via pregnane X receptor pathway in vitro.
Feng D, Tang T, Fan R, Luo J, Cui H, Wang Y, Gan P
BMC complementary and alternative medicine 2018 Dec 29;18(1):345
BMC complementary and alternative medicine 2018 Dec 29;18(1):345
Retinoic acid induces macrophage cholesterol efflux and inhibits atherosclerotic plaque formation in apoE-deficient mice.
Zhou W, Lin J, Chen H, Wang J, Liu Y, Xia M
The British journal of nutrition 2015 Aug 28;114(4):509-18
The British journal of nutrition 2015 Aug 28;114(4):509-18
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Supportive validation
- Submitted by
- Proteintech Group (provider)
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- Experimental details
- The PXR antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human PXR. This antibody recognizes human,mouse,rat antigen. The PXR antibody has been validated for the following applications: ELISA, WB analysis.