FNab04219

antibody from FineTest Biotech

Targeting: IL12B CLMF, CLMF2, IL-12B, NKSF, NKSF2

Western blot

ELISA

Antibody data

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Validation data

Product number: FNab04219 - Provider product page
Provider: FineTest Biotech
Product name: IL12B antibody
Antibody type: Polyclonal
Antigen: Recombinant protein fragment
Description: Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. Associates with IL23A to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis.
Reactivity: Human
Host: Rabbit
Conjugate: Unconjugated
Antigen sequence: interleukin 12B
Epitope: IgG
Isotype: IgG
Vial size: 100¦Ìg
Concentration: Immunogen affinity purified
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
Handling: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)

IL12B protein structure - FNab04219 shown in red.