Antibody data
- Antibody Data
- Antigen structure
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- Product number
- 508803 - Provider product page
- Provider
- BioLegend
- Proper citation
- BioLegend Cat#508803, RRID:AB_315530
- Product name
- LEAF™ Purified anti-human IL-12/IL-23 p40 [C8.6]
- Antibody type
- Monoclonal
- Antigen
- COS-expressed p40 subunit of human IL-12
- Description
- The C8.6 antibody reacts with human IL-12 p40 subunit of the IL-12 p70 heterodimer and IL-23 p40 subunit of the IL-23 p19/p40, as well as p40 monomer and homodimer. The C8.6 antibody has been reported to strongly inhibit different biological activities of IL-12, (e.g., IFN-gamma induction, mitogenic effects on PHA blasts, and enhancement of NK cell-mediated cytotoxicity). The C8.6 antibody can neutralize the bioactivity of natural or recombinant IL-12.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 50 µg
- Concentration
- 1 mg/ml
- Storage
- The antibody solution should be stored undiluted at 4 °C. This LEAF™ solution contains no preservative; handle under aseptic conditions.
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