511002

antibody from BioLegend
Targeting: IL12B CLMF, CLMF2, IL-12B, NKSF, NKSF2
Provider product page for 511002
ELISA

Antibody data

Product number
511002 - Provider product page
Provider
BioLegend
Proper citation
BioLegend Cat#511002, RRID:AB_2211913
Product name
Purified anti-human IL-12 (p70)
Antibody type
Monoclonal
Antigen
IL-12 (p70)
Description
Bioactive IL-12 is a potent regulator of cell-mediated immune responses and key mediator of Th1 cell development. Bioactive IL-12 is secreted by activated B lymphocytes, dendritic cells and macrophages as a 70 kD heterodimeric glycoprotein comprised of disulfide-bonded 35 kD and 40 kD subunits. The disulfide-linked p40 homodimer can bind to IL-12 receptors and antagonize the activities of bioactive IL-12. The 7B12 antibody reacts with human IL-12 p70 heterodimer, but shows no reactivity with IL-12 p35 or p40 monomer. The 7B12 has high affinity to human IL-12 p70 heterodimer.
Reactivity
Human
Host
Mouse
Conjugate
Unconjugated
Isotype
IgG
Vial size
500 µg
Concentration
0.5 mg/ml
Storage
The antibody solution should be stored undiluted at 4°C.
IL12B protein structure - 511002 shown in red.