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- Antigen structure
- References [12]
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- Validations
- Western blot [1]
- Flow cytometry [1]
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- Product number
- 12837-2-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#12837-2-AP, RRID:AB_2244279
- Product name
- CD247 antibody
- Antibody type
- Polyclonal
- Description
- CD247 antibody (Cat. #12837-2-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references m6A-Modified Nucleotide Bases Improve Translation of In Vitro-Transcribed Chimeric Antigen Receptor (CAR) mRNA in T Cells.
Fibroblast Activation Protein-Targeted CAR-T Cells Induce Apoptosis in Murine Cardiac Myofibroblasts.
ANKRD55 is a key regulator of T cell inflammation in multiple sclerosis.
Efficacy and safety evaluation of cross-reactive Fibroblast activation protein scFv-based CAR-T cells.
Targeting overexpressed antigens in glioblastoma via CAR T cells with computationally designed high-affinity protein binders.
Three-gene signature revealing the dynamics of lymphocyte infiltration in subchondral bone during osteoarthritis progression.
Cell volume controlled by LRRC8A-formed volume-regulated anion channels fine-tunes T cell activation and function.
Bruton tyrosine kinase inhibitors preserve anti-CD19 chimeric antigen receptor T-cell functionality and reprogram tumor micro-environment in B-cell lymphoma.
Targeting protein tyrosine phosphatases for CDK6-induced immunotherapy resistance.
Distinct immune and inflammatory response patterns contribute to the identification of poor prognosis and advanced clinical characters in bladder cancer patients.
The Transferrin Receptor-Directed CAR for the Therapy of Hematologic Malignancies.
Liver sinusoidal endothelial cell-mediated CD8 T cell priming depends on co-inhibitory signal integration over time.
Lao N, Li S, Ainciburu M, Barron N
International journal of molecular sciences 2026 Jan 13;27(2)
International journal of molecular sciences 2026 Jan 13;27(2)
Fibroblast Activation Protein-Targeted CAR-T Cells Induce Apoptosis in Murine Cardiac Myofibroblasts.
Li H, Zheng Q, Jiang Y, Yang L, Li S, Yang P, Yin G, Sun L
Cardiovascular therapeutics 2025;2025:7230505
Cardiovascular therapeutics 2025;2025:7230505
ANKRD55 is a key regulator of T cell inflammation in multiple sclerosis.
Wu C, Jiang M, Yang X, Liu Y, Huang B, Guo Y, Cao R, Cui Z, Deng G, Wang W, Guo M, Lin Z, Fan J, Zhang LM, Di Cesare Mannelli L, Pang T, Wang C, Zhang CJ
The Journal of clinical investigation 2025 Oct 15;135(20)
The Journal of clinical investigation 2025 Oct 15;135(20)
Efficacy and safety evaluation of cross-reactive Fibroblast activation protein scFv-based CAR-T cells.
Niu W, Wang B, Zhang Y, Wang C, Cao J, Li J, He Y, Lei P
Frontiers in immunology 2024;15:1433679
Frontiers in immunology 2024;15:1433679
Targeting overexpressed antigens in glioblastoma via CAR T cells with computationally designed high-affinity protein binders.
Xia Z, Jin Q, Long Z, He Y, Liu F, Sun C, Liao J, Wang C, Wang C, Zheng J, Zhao W, Zhang T, Rich JN, Zhang Y, Cao L, Xie Q
Nature biomedical engineering 2024 Dec;8(12):1634-1650
Nature biomedical engineering 2024 Dec;8(12):1634-1650
Three-gene signature revealing the dynamics of lymphocyte infiltration in subchondral bone during osteoarthritis progression.
Luo S, Liu Z, Zhang J, Chen Y, Lei Y, Gao X, Liu C, Chen Y, Liu C, Yan P, Chen Y, Li H, Zhao C, Wang H, Wang K, Wang C, Tian R, Yang P
International immunopharmacology 2024 Aug 20;137:112431
International immunopharmacology 2024 Aug 20;137:112431
Cell volume controlled by LRRC8A-formed volume-regulated anion channels fine-tunes T cell activation and function.
Wang Y, Sun Z, Ping J, Tang J, He B, Chang T, Zhou Q, Yuan S, Tang Z, Li X, Lu Y, He R, He X, Liu Z, Yin L, Wu N
Nature communications 2023 Nov 4;14(1):7075
Nature communications 2023 Nov 4;14(1):7075
Bruton tyrosine kinase inhibitors preserve anti-CD19 chimeric antigen receptor T-cell functionality and reprogram tumor micro-environment in B-cell lymphoma.
Luo W, Li C, Wu J, Tang L, Wang X, Zhang Y, Wu Z, Huang Z, Xu J, Kang Y, Xiong W, Deng J, Hu Y, Mei H
Cytotherapy 2023 Jul;25(7):739-749
Cytotherapy 2023 Jul;25(7):739-749
Targeting protein tyrosine phosphatases for CDK6-induced immunotherapy resistance.
Gao X, Wu Y, Chick JM, Abbott A, Jiang B, Wang DJ, Comte-Walters S, Johnson RH, Oberholtzer N, Nishimura MI, Gygi SP, Mehta A, Guttridge DC, Ball L, Mehrotra S, Sicinski P, Yu XZ, Wang H
Cell reports 2023 Apr 25;42(4):112314
Cell reports 2023 Apr 25;42(4):112314
Distinct immune and inflammatory response patterns contribute to the identification of poor prognosis and advanced clinical characters in bladder cancer patients.
Chang Z, Li R, Zhang J, An L, Zhou G, Lei M, Deng J, Yang R, Song Z, Zhong W, Qi D, Duan X, Li S, Sun B, Wu W
Frontiers in immunology 2022;13:1008865
Frontiers in immunology 2022;13:1008865
The Transferrin Receptor-Directed CAR for the Therapy of Hematologic Malignancies.
Guo Z, Zhang Y, Fu M, Zhao L, Wang Z, Xu Z, Zhu H, Lan X, Shen G, He Y, Lei P
Frontiers in immunology 2021;12:652924
Frontiers in immunology 2021;12:652924
Liver sinusoidal endothelial cell-mediated CD8 T cell priming depends on co-inhibitory signal integration over time.
Kaczmarek J, Homsi Y, van Üüm J, Metzger C, Knolle PA, Kolanus W, Lang T, Diehl L
PloS one 2014;9(6):e99574
PloS one 2014;9(6):e99574
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Jurkat cells were subjected to SDS PAGE followed by western blot with 12837-2-AP(CD247 antibody) at dilution of 1:500
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The CD247 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human CD247. This antibody recognizes human,mouse,rat antigen. The CD247 antibody has been validated for the following applications: ELISA, WB, IHC, FC analysis.
