Tissue expressionAmygdalaBasal gangliaCerebellumCerebral cortexChoroid plexusHippocampal formationHypothalamusMedulla oblongataMidbrainOlfactory bulbPonsSpinal cordThalamusWhite matterRetinaAdrenal glandParathyroid glandPituitary glandThyroid glandLungEsophagusSalivary glandTongueColonDuodenumRectumSmall intestineStomachGallbladderLiverPancreasKidneyUrinary bladderEpididymisProstateSeminal vesicleTestisBreastCervixEndometriumFallopian tubeOvaryPlacentaVaginaHeart muscleSkeletal muscleSmooth muscleAdipose tissueSkinAppendixBone marrowLymph nodeSpleenThymusTonsil02468101214
Cell line expressionAF22GAMGSH-SY5YU-138 MGU-251 MGU-87 MGHTCEpiHTERT-RPE1OE19CACO-2Hep G2CAPAN-2HEK 293NTERA-2RPTEC TERT1RT4PC-3SuSaA-431HaCaTSK-MEL-30WM-115A549HBEC3-KTSCLC-21HAN3-CABEWOEFO-21HeLaHTERT-HME1MCF7SiHaSK-BR-3T-47dHUVEC TERT2TIMEHSkMCASC diffASC TERT1BJBJ hTERT+BJ hTERT+ SV40 Large T+BJ hTERT+ SV40 Large T+ RasG12VFHDF/TERT166HBF TERT88HHSteCLHCN-M2RH-30U-2 OSU-2197DaudiHDLM-2HTEC/SVTERT24-BJURKATKarpas-707MOLT-4REHRPMI-8226U-266/70U-266/84U-698HAP1HELHL-60HMC-1K-562NB-4THP-1U-937024681012
Protein structure

ADRA1B

Adrenoceptor alpha 1B
 
Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1B-adrenergic receptor, which induces neoplastic transformation when transfected into NIH 3T3 fibroblasts and other cell lines. Thus, this normal cellular gene is identified as a protooncogene. This gene comprises 2 exons and a single large intron of at least 20 kb that interrupts the coding region. [provided by RefSeq, Jul 2008]
More gene data

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                        519 antibodies from 38 providers.

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                        2 antibodies
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                        17 antibodies
                        St John's Laboratory
                        4 antibodies
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                        16 antibodies
                        Cusabio Biotech Co., Ltd
                        3 antibodies
                        NovoPro Bioscience Inc.
                        6 antibodies
                        Boster Biological Technology
                        2 antibodies
                        Aviva Systems Biology
                        5 antibodies
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                        8 antibodies
                        Abcepta
                        8 antibodies
                        Abnova Corporation
                        7 antibodies
                        NSJ Bioreagents
                        2 antibodies
                        Bioworld Technology, Inc
                        1 antibody
                        Enzo Life Sciences
                        1 antibody
                        Antibodies.com
                        6 antibodies
                        Everest Biotech
                        2 antibodies
                        Affinity Biosciences
                        1 antibody
                        FineTest Biotech
                        1 antibody
                        Abbkine Scientific Co.Ltd.
                        1 antibody
                        GeneTex
                        5 antibodies
                        R&D Systems
                        8 antibodies
                        ProSci
                        6 antibodies
                        Atlas Antibodies
                        1 antibody
                        Abbexa
                        8 antibodies
                        Creative Biolabs
                        4 antibodies
                        MyBioSource
                        8 antibodies
                        Leading Biology
                        8 antibodies
                        Abbiotec
                        1 antibody
                        RabMAbs
                        1 antibody
                        United States Biological
                        71 antibodies
                        MilliporeSigma / Merck KGaA
                        4 antibodies
                        RayBiotech, Inc.
                        4 antibodies
                        GenWay
                        2 antibodies
                        Creative Diagnostics
                        3 antibodies