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ADRA1B
Adrenoceptor alpha 1BAlpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1B-adrenergic receptor, which induces neoplastic transformation when transfected into NIH 3T3 fibroblasts and other cell lines. Thus, this normal cellular gene is identified as a protooncogene. This gene comprises 2 exons and a single large intron of at least 20 kb that interrupts the coding region. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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| LSBio |  LS-C402150 |
Polyclonal |
WB
EL
IHC
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| Invitrogen Antibodies | AAR-018-200UL |
Polyclonal |
WB
ICC
IHC
FC
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| antibodies-online | ABIN1742133 |
1 references | Polyclonal |
WB
ICC
FC
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| OriGene | TA328701 |
Polyclonal |
WB
ICC
IHC
FC
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| Proteintech Group | 22419-1-AP |
3 references | Polyclonal |
WB
EL
FC
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