HPA024153

antibody from Atlas Antibodies

Targeting: CHKA CHK, CKI

Western blot (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

HPA024153

Provider

Atlas Antibodies

Proper citation

Atlas Antibodies Cat#HPA024153, RRID:AB_1846664

Product name

Anti-CHKA

Antibody type

Polyclonal

Description

Polyclonal Antibody against Human CHKA, Gene description: choline kinase alpha, Alternative Gene Names: CHK, CKI, Validated applications: IHC, WB, Uniprot ID: P35790, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Reactivity

Human

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

100 µl

Concentration

0.1 mg/ml

Storage

Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Handling

The antibody solution should be gently mixed before use.

References

Submitted references

Consideration of Metabolite Efflux in Radiolabelled Choline Kinetics

Li Y, Inglese M, Dubash S, Barnes C, Brickute D, Braga M, Wang N, Beckley A, Heinzmann K, Allott L, Lu H, Chen C, Fu R, Carroll L, Aboagye E
Pharmaceutics 2021;13(8):1246

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Novel Non-Congeneric Derivatives of the Choline Kinase Alpha Inhibitor ICL-CCIC-0019

Wang N, Brickute D, Braga M, Barnes C, Lu H, Allott L, Aboagye E
Pharmaceutics 2021;13(7):1078

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Spatial heterogeneity of radiolabeled choline positron emission tomography in tumors of patients with non-small cell lung cancer: first-in-patient evaluation of [18F]fluoromethyl-(1,2-2H4)-choline

Dubash S, Inglese M, Mauri F, Kozlowski K, Trivedi P, Arshad M, Challapalli A, Barwick T, Al-Nahhas A, Stanbridge R, Lewanski C, Berry M, Bowen F, Aboagye E
Theranostics 2020;10(19):8677-8690

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De novo phosphatidylcholine synthesis is required for autophagosome membrane formation and maintenance during autophagy

Andrejeva G, Gowan S, Lin G, Wong Te Fong A, Shamsaei E, Parkes H, Mui J, Raynaud F, Asad Y, Vizcay-Barrena G, Nikitorowicz-Buniak J, Valenti M, Howell L, Fleck R, Martin L, Kirkin V, Leach M, Chung Y
Autophagy 2019;16(6):1044-1060

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Imaging and Tissue Biomarkers of Choline Metabolism in Diffuse Adult Glioma: 18F-Fluoromethylcholine PET/CT, Magnetic Resonance Spectroscopy, and Choline Kinase α

Grech-Sollars M, Ordidge K, Vaqas B, Davies C, Vaja V, Honeyfield L, Camp S, Towey D, Mayers H, Peterson D, O’Neill K, Roncaroli F, Barwick T, Waldman A
Cancers 2019;11(12):1969

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Evaluation of the combination of the dual m-TORC1/2 inhibitor vistusertib (AZD2014) and paclitaxel in ovarian cancer models

Wong Te Fong A, Thavasu P, Gagrica S, Swales K, Leach M, Cosulich S, Chung Y, Banerji U
Oncotarget 2017;8(69):113874-113884

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Overexpression of CHKA contributes to tumor progression and metastasis and predicts poor prognosis in colorectal carcinoma

Hu L, Wang R, Cai J, Feng D, Yang G, Xu Q, Zhai Y, Zhang Y, Zhou W, Cai Q
Oncotarget 2016;7(41):66660-66678

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The novel choline kinase inhibitor ICL-CCIC-0019 reprograms cellular metabolism and inhibits cancer cell growth

Trousil S, Kaliszczak M, Schug Z, Nguyen Q, Tomasi G, Favicchio R, Brickute D, Fortt R, Twyman F, Carroll L, Kalusa A, Navaratnam N, Adejumo T, Carling D, Gottlieb E, Aboagye E
Oncotarget 2016;7(24):37103-37120