MAB7821

antibody from R&D Systems

Targeting: IL22 IL-21, IL-22, IL-D110, IL-TIF, ILTIF, MGC79382, MGC79384, TIFa, TIFIL-23, zcyto18

Blocking/Neutralizing (Recommended by provider)

Antibody Data

Product number

MAB7821

Provider

R&D Systems

Product name

Anti-Human IL-22 Monoclonal Antibody (Clone 142928)

Antibody type

Monoclonal

Antigen

E. coli-derived recombinant human IL-22, Ala34-Ile179

Description

Protein A or G purified from hybridoma culture supernatant

Reactivity

Human

Host

Mouse

Antigen sequence

Q9GZX6


Isotype

IgG

Vial size

500 µg

References

Submitted references

Interleukin-22 suppresses the growth of A498 renal cell carcinoma cells via regulation of STAT1 pathway.

Zhang F, Shang D, Zhang Y, Tian Y
PloS one 2011;6(5):e20382

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TH17 cytokines induce human airway smooth muscle cell migration.

Chang Y, Al-Alwan L, Risse PA, Roussel L, Rousseau S, Halayko AJ, Martin JG, Hamid Q, Eidelman DH
The Journal of allergy and clinical immunology 2011 Apr;127(4):1046-53.e1-2

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Overrepresentation of IL-17A and IL-22 producing CD8 T cells in lesional skin suggests their involvement in the pathogenesis of psoriasis.

Res PC, Piskin G, de Boer OJ, van der Loos CM, Teeling P, Bos JD, Teunissen MB
PloS one 2010 Nov 24;5(11):e14108

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IL-17 amplifies human contact hypersensitivity by licensing hapten nonspecific Th1 cells to kill autologous keratinocytes.

Pennino D, Eyerich K, Scarponi C, Carbone T, Eyerich S, Nasorri F, Garcovich S, Traidl-Hoffmann C, Albanesi C, Cavani A
Journal of immunology (Baltimore, Md. : 1950) 2010 May 1;184(9):4880-8