Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [3]
- Flow cytometry [2]
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Validation data
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- Product number
- 10-3026 - Provider product page
- Provider
- ABEOMICS Inc.
- Product name
- Anti-TLR2 Antibody
- Antibody type
- Monoclonal
- Description
- TLR2 (Toll-Like Receptors 2) is a member of the TLR (Toll-like receptor) family that plays a fundamental role in pathogen recognition and activation of innate immunity. TLR2 forms heterodimers with TLR1 and TLR6, which is the initial step in a cascade of events leading to significant innate immune responses, development of adaptive immunity to pathogens and protection from immune sequelae related to infection with these pathogens. TLR2 also interacts with a large number of non-TLR molecules, allowing for recognition of a great number and variety of PAMPs (pathogen-associated molecular patterns). TLR2 expression has been detected in immune cells, endothelial, and epithelial cells.
- Reactivity
- Human, Mouse
- Host
- Mouse
- Conjugate
- Unconjugated
- Antigen sequence
A partial length recombinant TLR2 p
rotein (amino acids 180-420) was us
ed as the immunogen for this antibo
dy.- Isotype
- IgG
- Antibody clone number
- ABM3A87
- Vial size
- 100 µg
- Concentration
- 0.5 mg/ml
- Storage
- Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeat freez thawing
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Supportive validation
- Submitted by
- ABEOMICS Inc. (provider)
- Main image
- Experimental details
- Western blot analysis of TLR2. Anti- TLR2 antibody (Clone: ABM3A87) was used at 2 µg/ml on mouse embryonic liver lysate.
- Protocol
- Protocol
Supportive validation
- Submitted by
- ABEOMICS Inc. (provider)
- Main image
- Experimental details
- Immunohistochemical analysis of TLR2 in human prostate tissue using TLR2 antibody (Clone: ABM3A87) at 5 µg/ml.
- Protocol
- Protocol
- Submitted by
- ABEOMICS Inc. (provider)
- Main image
- Experimental details
- Immunohistochemical analysis of TLR2 in human Colon tissue using TLR2 antibody (Clone: ABM3A87) at 10 µg/ml.
- Protocol
- Protocol
- Submitted by
- ABEOMICS Inc. (provider)
- Main image
- Experimental details
- Immunohistochemical analysis of TLR2 in Renal Cell Carcinoma using TLR2 antibody (Clone: ABM3A87) at 5 µg/ml.
- Protocol
- Protocol
Supportive validation
- Submitted by
- ABEOMICS Inc. (provider)
- Main image
- Experimental details
- Intracellular flow analysis of TLR2 in PBMC (Monocytes) using 0.5 µg/10^6 cells of TLR2 antibody (Clone: ABM3A87). Green represents isotype control; red represents anti-TLR2 antibody. Goat anti-Mouse PE conjugate was used as secondary.
- Protocol
- Protocol
- Submitted by
- ABEOMICS Inc. (provider)
- Main image
- Experimental details
- Intracellular flow analysis of TLR2 in THP-1 cells using 0.5 µg/10^6 cells of TLR2 antibody (Clone: ABM3A87). Green represents isotype control; red represents anti-TLR2 antibody. Goat anti-Mouse PE conjugate was used as secondary antibody.
- Protocol
- Protocol