Antibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations [0]
Submit
Validation data
Reference
Comment
Report error
- Product number
- 309701 - Provider product page
- Provider
- BioLegend
- Product name
- Purified anti-human CD282 (TLR2)
- Antibody type
- Monoclonal
- Antigen
- Human TLR2-transfected CHO cells
- Description
- Toll-like receptors are type I transmembrane signaling receptors which are critical for the innate host defense to pathogens. Toll-like receptor 2 (TLR2), known as CD282, has been identified as a receptor that is central to the innate immune system's response to lipoproteins of Gram-negative bacteria and Gram-positive bacteria, as well as a receptor for peptidoglycan and lipoteichoic acid and other bacterial cell membrane products. The TL2.1 antibody is useful for blocking studies. It has been reported to block TLR2 agonist-induced cellular activation.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 25 µg
- Concentration
- 0.5 mg/ml
- Storage
- The antibody solution should be stored undiluted at 4°C.
Submitted references Monocytes differentiated with GM-CSF and IL-15 initiate Th17 and Th1 responses that are contact-dependent and mediated by IL-15.
Bovine monocyte TLR2 receptors differentially regulate the intracellular fate of Mycobacterium avium subsp. paratuberculosis and Mycobacterium avium subsp. avium.
Vibrio vulnificus IlpA-induced cytokine production is mediated by Toll-like receptor 2.
High-mobility group box 1 activates integrin-dependent homing of endothelial progenitor cells.
Harris KM
Journal of leukocyte biology 2011 Oct;90(4):727-34
Journal of leukocyte biology 2011 Oct;90(4):727-34
Bovine monocyte TLR2 receptors differentially regulate the intracellular fate of Mycobacterium avium subsp. paratuberculosis and Mycobacterium avium subsp. avium.
Weiss DJ, Souza CD, Evanson OA, Sanders M, Rutherford M
Journal of leukocyte biology 2008 Jan;83(1):48-55
Journal of leukocyte biology 2008 Jan;83(1):48-55
Vibrio vulnificus IlpA-induced cytokine production is mediated by Toll-like receptor 2.
Goo SY, Han YS, Kim WH, Lee KH, Park SJ
The Journal of biological chemistry 2007 Sep 21;282(38):27647-58
The Journal of biological chemistry 2007 Sep 21;282(38):27647-58
High-mobility group box 1 activates integrin-dependent homing of endothelial progenitor cells.
Chavakis E, Hain A, Vinci M, Carmona G, Bianchi ME, Vajkoczy P, Zeiher AM, Chavakis T, Dimmeler S
Circulation research 2007 Feb 2;100(2):204-12
Circulation research 2007 Feb 2;100(2):204-12
No comments: Submit comment
No validations: Submit validation data