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Learn16668-1-AP
antibody from Proteintech Group
Targeting: CD40LG
CD154, CD40L, gp39, hCD40L, HIGM1, IMD3, TNFSF5, TRAP
Western blot
ELISAAntibody data
- Antibody Data
- Antigen structure
- References [19]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
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- Product number
- 16668-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#16668-1-AP, RRID:AB_2076318
- Product name
- CD40L/CD154 antibody
- Antibody type
- Polyclonal
- Description
- CD40L/CD154 antibody (Cat. #16668-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Intranasal CD40-targeted recombinant MERS-CoV S1 protein is superior to intramuscular immunization in eliciting systemic and mucosal immune responses in mice.
CD40LG Downregulation in Lung Adenocarcinoma: A Prognostic Biomarker Linked to Immune Cell Infiltration and Survival Outcomes.
From Wound Dressing to Tissue Regeneration: Bilayer Medicated Patches for Personalized Treatments of Chronic Wounds.
Porphyromonas gingivalis LPS-stimulated BMSC-derived exosome promotes osteoclastogenesis via miR-151-3p/PAFAH1B1.
Spheroid culture to select theoretical therapeutic drugs in intravascular large B-cell lymphoma.
Activation of V-Domain Immunoglobulin Suppressor of T-Cell Activation by Baloxavir Marboxil Ameliorates Systemic Lupus Erythematosus through Inhibiting Lysophosphatidylcholine/CD40 Ligand.
Liquiritigenin attenuates thrombosis by inhibiting P2Y(12)R-mediated Src/PLCγ2 signaling and cytoplasmic Ca(2+) mobilization in platelets.
Effects of Rhaponticum carthamoides (Willd.) Iljin on endothelial dysfunction and the inflammatory response in type 2 diabetes mellitus mice.
Glycosylation-Engineered Platelet Membrane-Coated Interleukin 10 Nanoparticles for Targeted Inhibition of Vascular Restenosis.
In vivo transfection of cytokine genes into tumor cells using a synthetic vehicle promotes antitumor immune responses in a visceral tumor model.
Bone Homeostasis Modulating Orthopedic Adhesive for the Closed-Loop Management of Osteoporotic Fractures.
Vascular restenosis reduction with platelet membrane coated nanoparticle directed M2 macrophage polarization.
Compression loading of osteoclasts attenuated microRNA-146a-5p expression, which promotes angiogenesis by targeting adiponectin.
Role of miR-145-5p/ CD40 in the inflammation and apoptosis of HUVECs induced by PM(2.5).
Promoting the activation of T cells with glycopolymer-modified dendritic cells by enhancing cell interactions.
YAP1 is essential for osteoclastogenesis through a TEADs-dependent mechanism.
PKCβII-mediated cross-talk of TRPV1/CB2 modulates the glucocorticoid-induced osteoclast overactivity.
C-reactive protein promotes atherosclerosis by increasing LDL transcytosis across endothelial cells.
TNF-α promotes early atherosclerosis by increasing transcytosis of LDL across endothelial cells: crosstalk between NF-κB and PPAR-γ.
Khan MY, Aljehani ND, Abdulal RH, Ghazwani A, Alsulaiman RM, Eyouni M, Shebbo S, Basabrain M, Sanki MA, Alsharef AA, Abdulaal WH, Albukhari A, Qadri I, Alluhaybi KA, Altorki T, Alhabbab R, Alghanmi M, Zawawi A, Abujamel TS, Algaissi A, Thulasi Raman SN, Alfaleh MA, Alghamdi BS, Azhari AA, Li X, Mahmoud AB, Hashem AM
Vaccine 2026 Jan 1;69:127975
Vaccine 2026 Jan 1;69:127975
CD40LG Downregulation in Lung Adenocarcinoma: A Prognostic Biomarker Linked to Immune Cell Infiltration and Survival Outcomes.
Tang P, Zhang R, Zhang Y, Ao Y, Wang Y, Wang G, Wang W, Xu J, Hu F, Zhu G
Journal of Cancer 2025;16(13):3884-3896
Journal of Cancer 2025;16(13):3884-3896
From Wound Dressing to Tissue Regeneration: Bilayer Medicated Patches for Personalized Treatments of Chronic Wounds.
Bernardoni S, Campodoni E, Vicinelli G, Saqawa M, Bonvicini F, Pulze L, Baranzini N, Costantini G, Montesi M, Gentilomi GA, Grimaldi A, Sandri M
ACS applied materials & interfaces 2025 Jun 18;17(24):35240-35261
ACS applied materials & interfaces 2025 Jun 18;17(24):35240-35261
Porphyromonas gingivalis LPS-stimulated BMSC-derived exosome promotes osteoclastogenesis via miR-151-3p/PAFAH1B1.
Dong JC, Liao Y, Zhou W, Sun MJ, Zhang HY, Li Y, Song ZC
Oral diseases 2025 Jan;31(1):206-216
Oral diseases 2025 Jan;31(1):206-216
Spheroid culture to select theoretical therapeutic drugs in intravascular large B-cell lymphoma.
Takai M, Shimada K, Furukawa K, Yamaga Y, Yoshiyama S, Kagaya Y, Suzuki T, Hayashi K, Shimada S, Karube K, Kiyoi H
Cancer science 2025 Jan;116(1):214-225
Cancer science 2025 Jan;116(1):214-225
Activation of V-Domain Immunoglobulin Suppressor of T-Cell Activation by Baloxavir Marboxil Ameliorates Systemic Lupus Erythematosus through Inhibiting Lysophosphatidylcholine/CD40 Ligand.
Luo Z, Zhang T, Wang P, Yuan D, Jin S, Di J, Ma R, Yang L, Wang X, Liu J
Chemical research in toxicology 2025 Jan 20;38(1):193-205
Chemical research in toxicology 2025 Jan 20;38(1):193-205
Liquiritigenin attenuates thrombosis by inhibiting P2Y(12)R-mediated Src/PLCγ2 signaling and cytoplasmic Ca(2+) mobilization in platelets.
Cheng L, Yu T, Xue H, Xiang S
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Dec;149:157553
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Dec;149:157553
Effects of Rhaponticum carthamoides (Willd.) Iljin on endothelial dysfunction and the inflammatory response in type 2 diabetes mellitus mice.
Nan G, Wang B, Lv X, Wang W, Luo Z, Yang G, Ding R, Wang J, Lin R, Wang H
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156134
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156134
Glycosylation-Engineered Platelet Membrane-Coated Interleukin 10 Nanoparticles for Targeted Inhibition of Vascular Restenosis.
Li F, Rong Z, Chen T, Wang P, Di X, Ni L, Liu C
International journal of nanomedicine 2023;18:5011-5030
International journal of nanomedicine 2023;18:5011-5030
In vivo transfection of cytokine genes into tumor cells using a synthetic vehicle promotes antitumor immune responses in a visceral tumor model.
Watanabe S, Takagi A, Yuba E, Kojima C, Dei N, Matsumoto A, Tanikawa J, Kawamura T, De Silva NH, Izawa T, Akazawa T, Kanegi R, Hatoya S, Inaba T, Sugiura K
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Nov;37(11):e23228
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Nov;37(11):e23228
Bone Homeostasis Modulating Orthopedic Adhesive for the Closed-Loop Management of Osteoporotic Fractures.
Liu C, Liu W, Qi B, Fan L, Liu S, Yang Q, Yang Y, Yang S, Zhang Y, Wei X, Zhu L
Small (Weinheim an der Bergstrasse, Germany) 2023 Nov;19(48):e2302704
Small (Weinheim an der Bergstrasse, Germany) 2023 Nov;19(48):e2302704
Vascular restenosis reduction with platelet membrane coated nanoparticle directed M2 macrophage polarization.
Li F, Rong Z, Zhang R, Niu S, Di X, Ni L, Liu C
iScience 2022 Oct 21;25(10):105147
iScience 2022 Oct 21;25(10):105147
Compression loading of osteoclasts attenuated microRNA-146a-5p expression, which promotes angiogenesis by targeting adiponectin.
Wang Y, Zheng Y, Li W
Science China. Life sciences 2022 Jan;65(1):151-166
Science China. Life sciences 2022 Jan;65(1):151-166
Role of miR-145-5p/ CD40 in the inflammation and apoptosis of HUVECs induced by PM(2.5).
Zhang X, Qi W, Shi Y, Li X, Yin J, Huo C, Zhang R, Zhao W, Ye J, Zhou L, Ye L
Toxicology 2021 Dec;464:152993
Toxicology 2021 Dec;464:152993
Promoting the activation of T cells with glycopolymer-modified dendritic cells by enhancing cell interactions.
Yu L, Feng R, Zhu L, Hao Q, Chu J, Gu Y, Luo Y, Zhang Z, Chen G, Chen H
Science advances 2020 Nov;6(47)
Science advances 2020 Nov;6(47)
YAP1 is essential for osteoclastogenesis through a TEADs-dependent mechanism.
Zhao L, Guan H, Song C, Wang Y, Liu C, Cai C, Zhu H, Liu H, Zhao L, Xiao J
Bone 2018 May;110:177-186
Bone 2018 May;110:177-186
PKCβII-mediated cross-talk of TRPV1/CB2 modulates the glucocorticoid-induced osteoclast overactivity.
Bellini G, Torella M, Manzo I, Tortora C, Luongo L, Punzo F, Colacurci N, Nobili B, Maione S, Rossi F
Pharmacological research 2017 Jan;115:267-274
Pharmacological research 2017 Jan;115:267-274
C-reactive protein promotes atherosclerosis by increasing LDL transcytosis across endothelial cells.
Bian F, Yang X, Zhou F, Wu PH, Xing S, Xu G, Li W, Chi J, Ouyang C, Zhang Y, Xiong B, Li Y, Zheng T, Wu D, Chen X, Jin S
British journal of pharmacology 2014 May;171(10):2671-84
British journal of pharmacology 2014 May;171(10):2671-84
TNF-α promotes early atherosclerosis by increasing transcytosis of LDL across endothelial cells: crosstalk between NF-κB and PPAR-γ.
Zhang Y, Yang X, Bian F, Wu P, Xing S, Xu G, Li W, Chi J, Ouyang C, Zheng T, Wu D, Zhang Y, Li Y, Jin S
Journal of molecular and cellular cardiology 2014 Jul;72:85-94
Journal of molecular and cellular cardiology 2014 Jul;72:85-94
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse small intestine tissue were subjected to SDS PAGE followed by western blot with 16668-1-AP(CD40LG antibody) at dilution of 1:1000
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human spleen using 16668-1-AP(CD40LG antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The CD154 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human CD154. This antibody recognizes human,mouse,rat antigen. The CD154 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
