Antibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
Submit
Validation data
Reference
Comment
Report error
- Product number
- ABIN359109 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Pyruvate Kinase, Liver and RBC (PKLR) (N-Term) antibody
- Antibody type
- Polyclonal
- Description
- Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Epitope
- N-Term
- Vial size
- 0.4 mL
- Storage
- Store the antibody undiluted at 2-8°C for one month or (in aliquots) at-20°C for longer.
- Handling
- Avoid repeated freezing and thawing.
Submitted references Liver pyruvate kinase polymorphisms are associated with type 2 diabetes in northern European Caucasians.
PKLR- GBA region shows almost complete linkage disequilibrium over 70 kb in a set of worldwide populations.
Structure and function of human erythrocyte pyruvate kinase. Molecular basis of nonspherocytic hemolytic anemia.
Congenital insensitivity to pain with anhidrosis (CIPA): novel mutations of the TRKA (NTRK1) gene, a putative uniparental disomy, and a linkage of the mutant TRKA and PKLR genes in a family with CIPA and pyruvate kinase deficiency.
Wang H, Chu W, Das SK, Ren Q, Hasstedt SJ, Elbein SC
Diabetes 2002 Sep;51(9):2861-5
Diabetes 2002 Sep;51(9):2861-5
PKLR- GBA region shows almost complete linkage disequilibrium over 70 kb in a set of worldwide populations.
Mateu E, Pérez-Lezaun A, Martínez-Arias R, Andrés A, Vallés M, Bertranpetit J, Calafell F
Human genetics 2002 Jun;110(6):532-44
Human genetics 2002 Jun;110(6):532-44
Structure and function of human erythrocyte pyruvate kinase. Molecular basis of nonspherocytic hemolytic anemia.
Valentini G, Chiarelli LR, Fortin R, Dolzan M, Galizzi A, Abraham DJ, Wang C, Bianchi P, Zanella A, Mattevi A
The Journal of biological chemistry 2002 Jun 28;277(26):23807-14
The Journal of biological chemistry 2002 Jun 28;277(26):23807-14
Congenital insensitivity to pain with anhidrosis (CIPA): novel mutations of the TRKA (NTRK1) gene, a putative uniparental disomy, and a linkage of the mutant TRKA and PKLR genes in a family with CIPA and pyruvate kinase deficiency.
Indo Y, Mardy S, Miura Y, Moosa A, Ismail EA, Toscano E, Andria G, Pavone V, Brown DL, Brooks A, Endo F, Matsuda I
Human mutation 2001 Oct;18(4):308-18
Human mutation 2001 Oct;18(4):308-18
No comments: Submit comment
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- WB
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- IHC