CABT-B11822

antibody from Creative Diagnostics

Targeting: ZFHX3 ATBF1, C16orf47, FLJ26184, ZNF927

Western blot (Recommended by provider)

ELISA (Recommended by provider)

Immunocytochemistry (Recommended by provider)

Antibody Data

Product number

CABT-B11822

Provider

Creative Diagnostics

Product name

Mouse anti-Human ZFHX3 monoclonal antibody, clone 4C2

Antibody type

Monoclonal

Description

This gene encodes a transcription factor with multiple homeodomains and zinc finger motifs, and regulates myogenic and neuronal differentiation. The encoded protein suppresses expression of the alpha-fetoprotein gene by binding to an AT-rich enhancer motif. The protein has also been shown to negatively regulate c-Myb, and transactivate the cell cycle inhibitor cyclin-dependent kinase inhibitor 1A (also known as p21CIP1). This gene is reported to function as a tumor suppressor in several cancers, and sequence variants of this gene are also associated with atrial fibrillation. Multiple transcript variants expressed from alternate promoters and encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]

Reactivity

Human

Host

Mouse

Conjugate

Unconjugated

Isotype

IgG

Antibody clone number

4C2

Vial size

100 _g

Storage

Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.